Aldona Dembinska-Kiec

Summary

Country: Poland

Publications

  1. ncbi request reprint Apo E isoforms, insulin output and plasma lipid levels in essential hypertension
    A Dembinska-Kiec
    Collegium Medicum, Jagiellonian University, Cracow, Poland
    Eur J Clin Invest 28:95-9. 1998
  2. doi request reprint Antioxidant phytochemicals against type 2 diabetes
    Aldona Dembinska-Kiec
    Department of Clinical Biochemistry, The Jagiellonian University Collegium Medicum, Kopernika 15A, Krakow 31 501, Poland
    Br J Nutr 99:ES109-17. 2008
  3. ncbi request reprint The selected pathophysiological aspects of PPARs activation
    B Kiec-Wilk
    Department of Clinical Biochemistry, Medical College Jagiellonian University, Kopernika 15A, 30 504 Krakow, Poland
    J Physiol Pharmacol 56:149-62. 2005
  4. ncbi request reprint Correlation of the -3826A >G polymorphism in the promoter of the uncoupling protein 1 gene with obesity and metabolic disorders in obese families from southern Poland
    B Kiec-Wilk
    Department of Clinical Biochemistry, Medical College, Jagiellonian University, Out patient Clinic of Obesity and Lipid Disorders, Krakow, Poland
    J Physiol Pharmacol 53:477-90. 2002
  5. ncbi request reprint Proangiogenic activity of beta-carotene is coupled with the activation of endothelial cell chemotaxis
    A Dembinska-Kiec
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Kopernika 15A, 31 501 Krakow, Poland
    Biochim Biophys Acta 1740:222-39. 2005
  6. ncbi request reprint Analysis of candidate genes in Polish families with obesity
    Małgorzata Malczewska-Malec
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Krakow, Poland
    Clin Chem Lab Med 42:487-93. 2004
  7. pmc Modulatory effect of high saturated fat diet-induced metabolic disturbances on angiogenic response in hepatocyte RXRα knockout mice
    Urszula Razny
    Department of Clinical Biochemistry, Medical College, Jagiellonian University, Kopernika 15A, PL 31 501 Krakow, Poland
    Pharmacol Rep 62:1078-89. 2010
  8. ncbi request reprint The TNF-alpha gene NcoI polymorphism at position -308 of the promoter influences insulin resistance, and increases serum triglycerides after postprandial lipaemia in familiar obesity
    Iwona Wybranska
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Krakow, Kopernika, Poland
    Clin Chem Lab Med 41:501-10. 2003
  9. ncbi request reprint An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis
    Tomasz Stompor
    Department of Nephrology, Coronary Artery Disease, and Clinical Biochemistry, Medical Faculty, Jagiellonian University, Cracow, Poland
    Am J Kidney Dis 41:203-11. 2003
  10. ncbi request reprint Metabolic effects of the HIV protease inhibitor--saquinavir in differentiating human preadipocytes
    Monika Bociaga-Jasik
    Chair of Gastroenterology, Hepatology and Infectious Diseases, Department of Infectious Diseases, Jagiellonian University, Collegium Medicum, Sniadeckich 5, PL 31 501 Krakow, Poland
    Pharmacol Rep 65:937-50. 2013

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Apo E isoforms, insulin output and plasma lipid levels in essential hypertension
    A Dembinska-Kiec
    Collegium Medicum, Jagiellonian University, Cracow, Poland
    Eur J Clin Invest 28:95-9. 1998
    ....
  2. doi request reprint Antioxidant phytochemicals against type 2 diabetes
    Aldona Dembinska-Kiec
    Department of Clinical Biochemistry, The Jagiellonian University Collegium Medicum, Kopernika 15A, Krakow 31 501, Poland
    Br J Nutr 99:ES109-17. 2008
    ....
  3. ncbi request reprint The selected pathophysiological aspects of PPARs activation
    B Kiec-Wilk
    Department of Clinical Biochemistry, Medical College Jagiellonian University, Kopernika 15A, 30 504 Krakow, Poland
    J Physiol Pharmacol 56:149-62. 2005
    ..This paper reviews evidences and hypotheses about the new pathophysiological aspects of PPARs activation...
  4. ncbi request reprint Correlation of the -3826A >G polymorphism in the promoter of the uncoupling protein 1 gene with obesity and metabolic disorders in obese families from southern Poland
    B Kiec-Wilk
    Department of Clinical Biochemistry, Medical College, Jagiellonian University, Out patient Clinic of Obesity and Lipid Disorders, Krakow, Poland
    J Physiol Pharmacol 53:477-90. 2002
    ....
  5. ncbi request reprint Proangiogenic activity of beta-carotene is coupled with the activation of endothelial cell chemotaxis
    A Dembinska-Kiec
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Kopernika 15A, 31 501 Krakow, Poland
    Biochim Biophys Acta 1740:222-39. 2005
    ..We conclude that beta-carotene in the physiological concentration range stimulates early steps of angiogenesis by the activation of cellular migration as well as matrix reorganization and decrease of cell adhesion...
  6. ncbi request reprint Analysis of candidate genes in Polish families with obesity
    Małgorzata Malczewska-Malec
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Krakow, Poland
    Clin Chem Lab Med 42:487-93. 2004
    ..We conclude that the polymorphisms we investigated were weakly correlated with obesity but significantly modified the risk factors of the metabolic syndrome...
  7. pmc Modulatory effect of high saturated fat diet-induced metabolic disturbances on angiogenic response in hepatocyte RXRα knockout mice
    Urszula Razny
    Department of Clinical Biochemistry, Medical College, Jagiellonian University, Kopernika 15A, PL 31 501 Krakow, Poland
    Pharmacol Rep 62:1078-89. 2010
    ..These results argue for independent participation of dyslipidemia and hyperleptinemia in pathology of angiogenic response associating metabolic syndrome...
  8. ncbi request reprint The TNF-alpha gene NcoI polymorphism at position -308 of the promoter influences insulin resistance, and increases serum triglycerides after postprandial lipaemia in familiar obesity
    Iwona Wybranska
    Department of Clinical Biochemistry, The Jagiellonian University Medical College, Krakow, Kopernika, Poland
    Clin Chem Lab Med 41:501-10. 2003
    ....
  9. ncbi request reprint An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis
    Tomasz Stompor
    Department of Nephrology, Coronary Artery Disease, and Clinical Biochemistry, Medical Faculty, Jagiellonian University, Cracow, Poland
    Am J Kidney Dis 41:203-11. 2003
    ....
  10. ncbi request reprint Metabolic effects of the HIV protease inhibitor--saquinavir in differentiating human preadipocytes
    Monika Bociaga-Jasik
    Chair of Gastroenterology, Hepatology and Infectious Diseases, Department of Infectious Diseases, Jagiellonian University, Collegium Medicum, Sniadeckich 5, PL 31 501 Krakow, Poland
    Pharmacol Rep 65:937-50. 2013
    ..The iatrogenic, HIV-related lipodystrophy is associated with development of the significant metabolic and cardiovascular complications. The underlying mechanisms of antiretroviral (ARV) drugs are not completely explored...
  11. ncbi request reprint An association between body mass index and markers of inflammation: is obesity the proinflammatory state in patients on peritoneal dialysis?
    Tomasz Stompor
    Department of Nephrology, Jagiellonian University, Krakow, Poland
    Perit Dial Int 23:79-83. 2003
  12. ncbi request reprint An analysis of the link between polymorphisms of the beta2 and beta3 adrenergic receptor gene and metabolic parameters among Polish Caucasians with familial obesity
    Małgorzata Malczewska-Malec
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Krakow Poland
    Med Sci Monit 9:CR225-34. 2003
    ..The aim of this study was to evaluate the influence of beta2 (Gln27>Glu) and beta3 (Trp64>Arg) adrenoreceptor gene polymorphisms on BMI and carbohydrate-lipid metabolism in Polish obese families...
  13. ncbi request reprint Renal transplantation ameliorates the progression of arterial stiffness in patients treated with peritoneal dialysis
    Tomasz Stompor
    Department of Nephrology, Jagiellonian University, Cracow, Poland
    Perit Dial Int 25:492-6. 2005
  14. ncbi request reprint beta-Carotene stimulates chemotaxis of human endothelial progenitor cells
    Beata Kiec-Wilk
    Department of Clinical Biochemistry, Medical College, Jagiellonian University, Krakow, Poland
    Clin Chem Lab Med 43:488-98. 2005
    ....
  15. pmc Increased nitric oxide availability attenuates high fat diet metabolic alterations and gene expression associated with insulin resistance
    Urszula Razny
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Kopernika 15a Street, 31 501 Cracow, Poland
    Cardiovasc Diabetol 10:68. 2011
    ..The purpose of this study was to investigate the effect of high fat diet on metabolism in mice with decreased (eNOS-/-) and increased (DDAH overexpressed) NO bioavailability...
  16. ncbi request reprint [Humanin and its derivatives as peptides with potential antiapoptotic and confirmed neuroprotective activities]
    Barbara Zapała
    Katedra i Zakład Biochemii Klinicznej, Uniwersytet Jagiellonski, Collegium Medicum, Krakow
    Przegl Lek 68:372-7. 2011
    ..The in vivo studies suggest that humanin may protect against cognitive impairment, also due to ischemia/reperfusion injury...
  17. doi request reprint Influence of fatty acids on mitochondrial metabolism of adipocyte progenitors and endothelial cells
    Anna Knapp
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Krakow, Poland
    Arch Physiol Biochem 118:128-34. 2012
    ..Objective: We investigated the effect of FFAs on the mitochondrial function in different cell populations under stress conditions...
  18. ncbi request reprint Leptin-induced differentiation of HUVEC
    Anna Polus
    Department of Clinical Chemistry, The Jagiellonian University Medical College, Krakow, Poland
    Acta Cardiol 59:229-30. 2004
  19. ncbi request reprint The microarray expression analysis identifies BAX as a mediator of beta-carotene effects on apoptosis
    Marek Bodzioch
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Nutr Cancer 51:226-35. 2005
    ..However, beta-carotene-induced expression changes of BAX and other BCL2 pathway genes did not lead to the predicted induction of apoptosis in the A375 cells...
  20. ncbi request reprint Mitochondrial function and apoptosis of peripheral mononuclear cells (PBMCs) in the HIV infected patients
    Monika Bociaga-Jasik
    Chair of Gastroenterology, Hepatology and Infectious Diseases, Department of Infectious Diseases Jagiellonian University, Collegium Medicum, Sniadeckich 5, 31 531 Krakow, Poland
    Curr HIV Res 11:263-70. 2013
    ....
  21. ncbi request reprint Insulin resistance and lipids in hypertensive women on hormone replacement therapy
    Kalina Kawecka-Jaszcz
    I Cardiac Department, Jagiellonian University, Medical College, Krakow, Poland
    Blood Press 11:28-34. 2002
    ..In conclusion, combined percutaneous HRT may reduce the lipid-depended cardiovascular risk in postmenopausal women with arterial hypertension...
  22. ncbi request reprint Regulation of platelet adhesion by oxidized lipoproteins and oxidized phospholipids
    Jadwiga Hartwich
    Department of Clinical Biochemistry, Jagiellonian University Collegium Medicum Kraków, Poland
    Platelets 13:141-51. 2002
    ..The effect of okadaic acid on CD36 and CD41 argue for the participation of phosphorylation-dependent reorganization of cellular trafficking and microtubule organization by ox-PAPC...
  23. ncbi request reprint Role of microRNAs in endothelial cell pathophysiology
    Teresa Staszel
    Genetic Diagnostics and Nutrigenomics Unit, Department of Clinical Biochemistry, Jagiellonian University, Medical College, Krakow, Poland
    Pol Arch Med Wewn 121:361-6. 2011
    ..Studies show that miRNA expression analysis can be used in the diagnosis and treatment of various diseases; however, additional research is needed before it is used in routine clinical setting...
  24. doi request reprint Evidence for potential functionality of nuclearly-encoded humanin isoforms
    Marek Bodzioch
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Kopernika 15A, 31 501 Krakow, Poland
    Genomics 94:247-56. 2009
    ..Cytoprotection against the STS-induced apoptosis conferred by the polymorphic HN5 variant, in which threonine in position 13 is replaced with isoleucine, is reduced compared to the wild type HN5 peptide...
  25. ncbi request reprint Genetic factors in hypertension. Angiotensin-converting enzyme polymorphism
    Danuta Czarnecka
    First Cardiac Department, Medical College, Jagiellonian University, Cracow, Poland
    Kardiol Pol 61:1-10; discussion 11. 2004
    ....
  26. ncbi request reprint Modulation of the human preadipocyte mitochondrial activity by beta-carotene
    Agnieszka Sliwa
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Krakow, Poland
    Acta Biochim Pol 59:39-41. 2012
    ..We conclude, that BC, the known antioxidant may decrease oxidative phosphorylation capacity of mitochondria...
  27. doi request reprint Lipoprotein profile, plasma ischemia modified albumin and LDL density change in the course of postprandial lipemia. Insights from the LIPGENE study
    Jadwiga Hartwich
    Department of Clinical Biochemistry, Jagiellonian University School of Medicine, Krakow, Poland
    Scand J Clin Lab Invest 70:201-8. 2010
    ..No expected associations between measures of central adiposity (waist, WHR), adipose tissue insulin resistance (Adipo-IR), and postprandial responses of TG, TC, LDL-C, HDL-C, LDLdens and IMA/Alb ratio were found in subgroup analysis...
  28. ncbi request reprint Evaluation of genetic predisposition to insulin resistance by nutrient-induced insulin output ratio (NIOR)
    Iwona Wybranska
    Department of Clinical Biochemistry, The Jagiellonian University, Medical College, Krakow, Poland
    Clin Chem Lab Med 45:1124-32. 2007
    ..The aim of this study was to identify correlation between the risk originating from gene variation and diet-dependent development of insulin resistance...
  29. doi request reprint Variants of the adiponectin gene and type 2 diabetes in a Polish population
    Magdalena Szopa
    Department of Metabolic Diseases, Medical College, Jagiellonian University, 15 Kopernika Street, 31 501, Krakow, Poland
    Acta Diabetol 46:317-22. 2009
    ..391G>A and +276G>T were independently associated with T2DM. Finally, we conclude that the adiponectin gene polymorphisms are associated with T2DM and prediabetic quantitative traits in Polish Caucasians...
  30. pmc Apoptosis-related gene expression in glioblastoma (LN-18) and medulloblastoma (Daoy) cell lines
    Iwona Wybranska
    Department of Genetic Diagnostics and Nutrigenomics, Chair of Clinical Biochemistry, The Jagiellonian University, Medical College, Krakow, Poland
    Hum Cell 26:137-48. 2013
    ..These results provided a novel molecular characterization of important human cancer cell lines, which might provide a useful research tool for investigating the experimental model of the CNS cell. ..
  31. ncbi request reprint Trends and dynamics of changes in calcification score over the 1-year observation period in patients on peritoneal dialysis
    Tomasz P Stompór
    Department of Nephrology, Medical Faculty, Jagiellonian University, Cracow, Poland
    Am J Kidney Dis 44:517-28. 2004
    ....
  32. pmc Impaired leptin activity in New Zealand Obese mice: model of angiogenesis
    Lukasz Wator
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Kopernika 15A, 31 501, Cracow, Poland
    Genes Nutr 3:177-80. 2008
    ..Changes in leptin concentration were not accompanied by significant angiogenic response. This lack of leptin activity and impaired signal transduction at the molecular level suggests malfunction of the leptin receptor in NZO mice...
  33. ncbi request reprint [Growth factors and cytokines (TGFBeta, bFGF and IGF-1) and cardiac left ventricular hypertrophy in hypertension]
    Beata Kiec-Wilk
    Zaklad Biochemii Klinicznej Katedry Biochemii Klinicznej, Collegium Medicum, Uniwersytet Jagiellonski, Krakow
    Kardiol Pol 64:S586-90. 2006
    ..Discussed growth factors and cytokines and cell signalling pathways related to them might in future appear as targets for therapeutic intervention...
  34. ncbi request reprint The effect of the plasma n-3/n-6 polyunsaturated fatty acid ratio on the dietary LDL phenotype transformation - insights from the LIPGENE study
    Jadwiga Hartwich
    Dept Clinical Biochemistry, Jagiellonian University School of Medicine, Krakow, Poland
    Clin Nutr 28:510-5. 2009
    ..LDL phenotype B is associated with obesity, insulin resistance, hypertriglyceridemia and oxidative stress. The effect of plasma n-3/n-6 PUFA ratio on LDL phenotype transformation was investigated...
  35. pmc Hepatocyte RXR alpha deletion in mice leads to inhibition of angiogenesis
    Urszula Razny
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Kopernika 15a Street, 31 501, Cracow, Poland
    Genes Nutr 4:69-72. 2009
    ..Our results suggest that impaired fatty acid metabolism in liver (hRXRalpha-deficient mice) leads to impaired angiogenesis due to lipotoxicity and promotion of adipogenesis...
  36. ncbi request reprint A724A polymorphism of sarco(endo)plasmic reticulum Ca2+-ATPase 2 (SERCA2) in hypertensive patients
    Beata Kiec-Wilk
    Clinical Biochemistry Department, Medical College Jagiellonian University, Krakow, Poland
    Clin Chem Lab Med 45:467-70. 2007
    ..The aim of this study was to screen for mutations in the ATP2A2 gene, in hypertensive patients compared to healthy controls...
  37. ncbi request reprint Peripheral blood concentrations of TGFβ1, IGF-1 and bFGF and remodelling of the left ventricle and blood vessels in hypertensive patients
    Beata Kiec-Wilk
    Clinical Biochemistry, Jagiellonian University Medical College, Krakow, Poland
    Kardiol Pol 68:996-1002. 2010
    ..Studies performed on animal models as well as clinical trials on aetiology of left ventricular hypertrophy (LVH), documented elevated level of both mRNA and proteins of TGFβ1 and IGF-1...
  38. ncbi request reprint Selected growth factors in peritoneal dialysis: their relationship to markers of inflammation, dialysis adequacy, residual renal function, and peritoneal membrane transport
    Tomasz Stompor
    Department of Nephrology, Jagiellonian University, Krakow, Poland
    Perit Dial Int 22:670-6. 2002
    ..The potential link between the above substances and dialysis adequacy was also explored...
  39. ncbi request reprint 17beta-estradiol- and lipopolysaccharide-induced changes in nitric oxide, tumor necrosis factor-alpha and vascular endothelial growth factor release from RAW 264.7 macrophages
    Agnieszka Tomaszewska
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Cracow, Poland
    Gynecol Obstet Invest 56:152-9. 2003
    ..A concentration-dependent inhibitory effect of 17betaE(2) on NO and TNFalpha release was observed at low physiological concentrations, whereas the VEGF gene expression and protein levels were upregulated by 17betaE(2) in RAW 264.7 cells...
  40. pmc Connexin 43 and metabolic effect of fatty acids in stressed endothelial cells
    Beata Kiec-Wilk
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Krakow, Poland
    Genes Nutr 7:257-63. 2012
    ....
  41. ncbi request reprint Dexamethasone inhibits TNF-alpha synthesis more effectively in Alzheimer's disease patients than in healthy individuals
    Tomasz Dziedzic
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Dement Geriatr Cogn Disord 16:283-6. 2003
    ..These results suggest that cytokine synthesis in AD patients could be regulated by glucocorticoids in a different way than in nondemented subjects...
  42. ncbi request reprint L-arginine supplementation does not inhibit neointimal formation after coronary stenting in human beings: an intravascular ultrasound study
    Dariusz Dudek
    Second Department of Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland
    Am Heart J 147:E12. 2004
    ..The aim of the study was to assess the influence of L-arginine administration on neointimal proliferation after coronary stenting in human beings...
  43. ncbi request reprint Expression of fucosyltransferases contributes to melanoma invasive phenotype
    Dorota Ciołczyk-Wierzbicka
    Department of Medical Biochemistry, Medical College, Jagiellonian University, M Kopernika 7, 31 034, Krakow, Poland
    Med Chem 3:418-24. 2007
    ..The results suggest that higher expression of fucosyltransferases (FUT-1, FUT-4) might be an important step in the formation of surface structures that facilitate metastasis of melanoma...
  44. ncbi request reprint Humanins, the neuroprotective and cytoprotective peptides with antiapoptotic and anti-inflammatory properties
    Barbara Zapała
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Kopernika 15A, PL31 501 Kraków, Poland
    Pharmacol Rep 62:767-77. 2010
    ..In vivo studies suggest that HN may also protect against cognitive impairment due to ischemia/reperfusion injury...
  45. ncbi request reprint Phospholamban gene mutations are not associated with hypertrophic cardiomyopathy in patients from southern Poland
    Paweł Petkow-Dimitrow
    2nd Department of Cardiology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Kardiol Pol 69:134-7. 2011
    ..Hypertrophic cardiomyopathy (HCM) is a genetic disease. The role of phospholamban (PLN) gene mutations is the development of HCM has not been established...
  46. pmc Angiogenesis in the New Zealand obese mouse model fed with high fat diet
    Adriana Balwierz
    Department of Clinical Biochemistry, Collegium Medicum, Jagiellonian University, Cracow, Poland
    Lipids Health Dis 8:13. 2009
    ..Aim of this study was to check the effect of high fat diet on changes in biochemical parameters as well as on process of angiogenesis in NZO mice...
  47. doi request reprint The CpG island methylation regulated expression of endothelial proangiogenic genes in response to β-carotene and arachidonic acid
    Beata Kiec-Wilk
    Department of Medical Biochemistry, Jagiellonian University Medical College, Krakow, Poland
    Nutr Cancer 63:1053-63. 2011
    ..However more research is necessary to confirm this hypothesis...
  48. ncbi request reprint Changes in common carotid artery intima-media thickness over 1 year in patients on peritoneal dialysis
    Tomasz Stompor
    Chair and Department of Nephrology, Jagiellonian University, 15c Kopernika Str, 31 501 Cracow, Poland
    Nephrol Dial Transplant 20:404-12. 2005
    ....
  49. ncbi request reprint Effects of oral L-arginine on the pulsatility indices of umbilical artery and middle cerebral artery in preterm labor
    Krzysztof Rytlewski
    Department of Gynecology and Obstetrics, Jagiellonian University Medical College, Krakow, Poland
    Eur J Obstet Gynecol Reprod Biol 138:23-8. 2008
    ..The objective of the study was the estimation of the influence of oral supplementation with low-dose l-arginine on feto-placental circulation in women with threatened preterm labor...
  50. ncbi request reprint Carotenoids: risk or benefit for health
    Aldona Dembinska-Kiec
    Department of Clinical Biochemistry, Jagiellonian University Medical College, Kopernika 15A, PL 31 501 Krakow, Poland
    Biochim Biophys Acta 1740:93-4. 2005
  51. ncbi request reprint Gender does not influence event-free survival in patients with ischaemic heart disease undergoing non-emergency coronary angiography. A single centre analysis
    Piotr Jankowski
    1st Department of Cardiology, Collegium Medicum Jagiellonian University, Cracow, Poland
    Kardiol Pol 65:475-84; discussion 485. 2007
    ..In addition, available data on the prognosis in this condition in men and women are also scarce...