Ewa Bien

Summary

Country: Poland

Publications

  1. ncbi [Soft tissue sarcomas of the parameningeal region in children--own observations]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 11:319-23. 2007
  2. ncbi [Genitourinary soft tissue sarcomas located outside bladder and prostate in children treated according to the CWS-96 protocol--report from the Polish Paediatric Solid Tumours Study Group]
    Ewa Bien
    Ośrodki Polskiej Pediatrycznej Grupy Guzów Litych
    Med Wieku Rozwoj 9:507-15. 2005
  3. ncbi [Cardio-vascular disorders at the time of diagnosis of malignant solid tumours in children--own experiences]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku
    Med Wieku Rozwoj 9:551-9. 2005
  4. ncbi [Clinical characteristics and therapy outcome in children with stage IV Hodgkin's lymphoma--the experience of two oncological centres]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 10:631-8. 2006
  5. ncbi Serum level of soluble interleukin-2 receptor alpha correlates with the clinical course and activity of Wilms' tumour and soft tissue sarcomas in children
    E Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Biomarkers 12:203-13. 2007
  6. ncbi Sarcomas in children with neurofibromatosis type 1-poor prognosis despite aggressive combined therapy in four patients treated in a single oncological institution
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University, 7 Debinki Street, 80 211 Gdansk, Poland
    Childs Nerv Syst 23:1147-53. 2007
  7. ncbi Serum soluble interleukin 2 receptor alpha in human cancer of adults and children: a review
    E Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Biomarkers 13:1-26. 2008
  8. ncbi [Therapeutic difficulties in soft tissue sarcoma occurring in children with neurofibromatosis type 1 - own observations]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, Gdańsku, Poland
    Med Wieku Rozwoj 12:477-84. 2008
  9. ncbi Poor-risk high-grade gliomas in three survivors of childhood acute lymphoblastic leukaemia--an overview of causative factors and possible therapeutic options
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211 Gdansk, Poland
    Childs Nerv Syst 25:619-26. 2009
  10. ncbi Pre-treatment serum levels of interleukin-10, interleukin-12 and their ratio predict response to therapy and probability of event-free and overall survival in childhood soft tissue sarcomas, Hodgkin's lymphomas and acute lymphoblastic leukemias
    Ewa Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211 Gdansk, Poland
    Clin Biochem 42:1144-57. 2009

Collaborators

Detail Information

Publications44

  1. ncbi [Soft tissue sarcomas of the parameningeal region in children--own observations]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 11:319-23. 2007
    ..Soft tissue sarcomas (STS) non-Hodgkin's lymphomas and less frequently nasopharyngeal carcinomas are the most common malignancies located in the parameningeal region in children...
  2. ncbi [Genitourinary soft tissue sarcomas located outside bladder and prostate in children treated according to the CWS-96 protocol--report from the Polish Paediatric Solid Tumours Study Group]
    Ewa Bien
    Ośrodki Polskiej Pediatrycznej Grupy Guzów Litych
    Med Wieku Rozwoj 9:507-15. 2005
    ..Analysis of therapy efficacy in non-bladder/prostate genitourinary sarcomas in children treated from I'1997 to VI'2003 with CWS-96 protocol in Poland...
  3. ncbi [Cardio-vascular disorders at the time of diagnosis of malignant solid tumours in children--own experiences]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku
    Med Wieku Rozwoj 9:551-9. 2005
    ..The aim of the study was to evaluate the frequency and characteristics of cardiological and vascular disorders in the initial phase of malignant solid tumors in children...
  4. ncbi [Clinical characteristics and therapy outcome in children with stage IV Hodgkin's lymphoma--the experience of two oncological centres]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 10:631-8. 2006
    ..THE AIM of the study was to analyze the initial symptoms, course and results of oncological therapy in children with stage IV of Hodgkin's disease...
  5. ncbi Serum level of soluble interleukin-2 receptor alpha correlates with the clinical course and activity of Wilms' tumour and soft tissue sarcomas in children
    E Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Biomarkers 12:203-13. 2007
    ..Thus, sIL-2Ralpha determination may be of some value in the diagnostics and treatment monitoring of childhood WT and SA...
  6. ncbi Sarcomas in children with neurofibromatosis type 1-poor prognosis despite aggressive combined therapy in four patients treated in a single oncological institution
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University, 7 Debinki Street, 80 211 Gdansk, Poland
    Childs Nerv Syst 23:1147-53. 2007
    ..Patients with neurofibromatosis type 1 (NF1) are predisposed to developing soft tissue sarcomas (STS)...
  7. ncbi Serum soluble interleukin 2 receptor alpha in human cancer of adults and children: a review
    E Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Biomarkers 13:1-26. 2008
    ....
  8. ncbi [Therapeutic difficulties in soft tissue sarcoma occurring in children with neurofibromatosis type 1 - own observations]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, Gdańsku, Poland
    Med Wieku Rozwoj 12:477-84. 2008
    ..CONCLUSION: basing on our own observations STS in NF1 seems to have poor prognosis in spite of combined therapy. Since early diagnosis is essential, children with NF1 should remain under the care of the oncologist...
  9. ncbi Poor-risk high-grade gliomas in three survivors of childhood acute lymphoblastic leukaemia--an overview of causative factors and possible therapeutic options
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211 Gdansk, Poland
    Childs Nerv Syst 25:619-26. 2009
    ..Although many predisposing factors exist (including systemic or intrathecal chemotherapy, young age, brain infiltration and genetic predispositions), cranial irradiation appears to be the strongest one...
  10. ncbi Pre-treatment serum levels of interleukin-10, interleukin-12 and their ratio predict response to therapy and probability of event-free and overall survival in childhood soft tissue sarcomas, Hodgkin's lymphomas and acute lymphoblastic leukemias
    Ewa Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211 Gdansk, Poland
    Clin Biochem 42:1144-57. 2009
    ..Deregulated serum IL-10, IL-12 and their reciprocal balance have been stated in malignancies of adults. In children with cancer the issue has not been investigated so far...
  11. ncbi Angiosarcoma in children - still uncontrollable oncological problem. The report of the Polish Paediatric Rare Tumours Study
    E Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Gdansk
    Eur J Cancer Care (Engl) 18:411-20. 2009
    ..Complete primary excision is unfeasible, even in seemingly local stages. The response to chemotherapy is poor and the large number of metastatic recurrences suggests a need for systemic therapy modifications...
  12. ncbi [Analysis of factors influencing treatment results in children with soft tissue head and neck sarcomas - in the material of the Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologiii Endokrynologii Akademii Medycznej w Gdańsku, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 12:1074-81. 2008
    ....
  13. ncbi [Malignant vascular tumours in children -- report from the Polish Pediatric Rare Tumors Study]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 8:145-58. 2004
    ..Malignant vascular tumours represent a rare group of neoplasms, usually treated according to protocols for soft tissue sarcomas...
  14. ncbi Retrospective multi-institutional study on hemangiopericytoma in Polish children
    Ewa Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Pediatr Int 51:19-24. 2009
    ..Pediatric hemangiopericytoma (HPC) is an extremely rare vascular tumor with little data available on its clinical course and management...
  15. ncbi [Diagnostic and prognostic significance of serum soluble interleukin 2 receptor in children with malignancies]
    Ewa Bien
    Kliniki Pediatrii, Hematologii, Onkologii i Endokrynologii oraz, Akademii Medycznej w Gdansku
    Wiad Lek 59:10-5. 2006
    ..The significance of sIL-2R as a marker of pediatric malignancies activity has not been evaluated so far. The aim of the study was to determine the clinical role of sIL-2R in diagnostics and prognosis in children with neoplasms...
  16. ncbi [Malignant neoplasms localised in the parameningeal region in children treated at two Polish oncological centres-diagnostic and therapeutic dilemmas]
    Ewa Bieań
    Klinika Pediatrii, Hematologii, Onkologie i Endokrynologii AM w Gdańsku
    Med Wieku Rozwoj 9:449-61. 2005
    ..In two of them (with MTM) the direct cause of death was myelosupressive, gastrotoxic and infectious complications of antitumour therapy. One child still undergoes treatment for MTM relapse...
  17. ncbi [Complications in children cured from Hodgkin's disease]
    Teresa Stachowicz-Stencel
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 10:613-21. 2006
    ..THE AIM of the study was to evaluate the incidence of pulmonary complications in children cured from Hodgkin's disease (HD)...
  18. ncbi [Solid tumours of the vertebral column and spinal cord in children. Reasons and consequences of diagnostic delay]
    Elzbieta Drozynska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 8:183-91. 2004
    ..Such localisation of neoplastic disease creates problems, connected with the risk of irreversible damage of neurological functions. It is essential to make a proper diagnosis very early...
  19. ncbi [Clinical significance of erythrocyte sedimentation rate, C-reactive protein and serum lactate dehydrogenase levels in the diagnosis, prognosis and treatment monitoring of children suffering from cancer]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 8:1081-9. 2004
    ..Moreover, the pre-treatment LDH level appeared to have an important role in prognosis of the overall survival rate...
  20. ncbi [Malignant pelvic neoplasms in children treated in two Polish oncology centres]
    Teresa Stachowicz-Stencel
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 8:159-68. 2004
    ..Extensive diagnostic and therapeutic dilemmas appear in children With primary malignant neoplasms located in the minor pelvis...
  21. ncbi [Soft tissue sarcomas of bladder and prostate in children treated according to the CWS-96 protocol--report of the Polish Paediatric Solid Tumours Study Group]
    Teresa Stachowicz-Stencel
    Ośrodki Polskiej Pediatrycznej Grupy Guzów Litych Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku
    Med Wieku Rozwoj 9:495-506. 2005
    ..analysis of the course, outcome and therapy complications in bladder/prostate soft tissue sarcomas (STS) in children treated from I'1997 to II'2003 according to CWS-96 protocol in Poland...
  22. ncbi [Second neoplasms in children with solid tumours in the years 1992-2007. Experiences of Gdańsk medical academy]
    Joanna Stefanowicz
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii Akademia Medyczna w Gdańsku, ul M Curie Skłodowskiej 3a, Gdansk, Poland
    Med Wieku Rozwoj 12:1141-7. 2008
    ..The aim of the study was to assess the frequency of a second neoplasm and its clinical course in children treated in Gdańsk in the years 1992-2007...
  23. ncbi The serum levels of soluble interleukin-2 receptor alpha and lactate dehydrogenase but not of B2-microglobulin correlate with selected clinico-pathological prognostic factors and response to therapy in childhood soft tissue sarcomas
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211, Gdansk, Poland
    J Cancer Res Clin Oncol 136:293-305. 2010
    ....
  24. ncbi [Neurologic symptoms in the course of neuroblastoma in children. Own observations]
    Katarzyna Połczyńska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku
    Med Wieku Rozwoj 9:477-86. 2005
    ....
  25. ncbi [Diagnostic and therapeutic difficulties in soft tissue sarcomas localized in nonparameningeal head and neck region--own experiences]
    Teresa Stachowicz-Stencel
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii Akademii Medycznej w Gdańsku
    Med Wieku Rozwoj 9:487-94. 2005
    ..The aim of the study was to analyze the reasons for disappointing results of oncological therapy in children with MTM treated between 1992 and 2004...
  26. ncbi Thymic carcinoma in children: a report from the Polish Pediatric Rare Tumors Study
    Teresa Stachowicz-Stencel
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University, Gdansk, Poland
    Pediatr Blood Cancer 54:916-20. 2010
    ..They are usually at an advanced stage when diagnosed and have both high recurrence and poor survival rates. In this report, the aim is to explore our experience in the treatment of thymic carcinomas in Polish children...
  27. ncbi Factors predicting survival in childhood malignant and intermediate vascular tumors : retrospective analysis of the Polish and German cooperative paediatric soft tissue sarcoma study groups and review of the literature
    Ewa Bien
    Department of Paediatrics, Medical University of Gdansk, Gdansk, Poland
    Ann Surg Oncol 17:1878-89. 2010
    ..The rarity of malignant and intermediate vascular tumors in children means that little is known about their clinical course, optimal treatment, and variables predicting survival...
  28. ncbi [Initial results of the treatment of six patients with high risk neuroblastoma in the years 2002--2006]
    Elzbieta Drozynska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 11:325-30. 2007
    ..Aim of the study was the evaluation of treatment results after using new methods of therapy...
  29. ncbi Neuroblastoma and opsoclonus-myoclonus-ataxia syndrome--clinical and pathological characteristics
    Joanna Stefanowicz
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Folia Neuropathol 46:176-85. 2008
    ..Opsoclonus-myoclonus-ataxia (OMA) syndrome is the most common paraneoplastic neurological syndrome in childhood...
  30. ncbi Multiple primary cranio-spinal tumours in a 13-year-old female with neurofibromatosis type 2 management strategy
    Teresa Stachowicz-Stencel
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, Gdansk, Poland
    Childs Nerv Syst 27:175-8. 2011
    ..Herein, we report one case of NF2 treated with multivariate chemotherapy...
  31. ncbi [Does beta-2 microglobulin measurement play role in diagnostics of childhood malignancies?]
    Ewa Bien
    Kliniki Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademii Medycznej w Gdansku
    Wiad Lek 57:8-11. 2004
    ..Measurement of serum beta 2-M seems to have no clinical value in the diagnostics of pediatric malignant solid tumors...
  32. ncbi G-CSF therapy and catheter-related Gram-positive sepsis increase serum IL-2 receptor α level and may falsely suggest a relapse in children with soft tissue sarcomas unless serum beta2-microglobulin, lactate dehydrogenase and C-reactive protein levels are
    Ewa Bien
    Department of Pediatrics, Hematology, Oncology and Endocrinology, Medical University of Gdansk, 7 Debinki Street, 80 211 Gdansk, Poland
    Cytokine 55:347-52. 2011
    ..Determination of serum B2-M, LDH and CRP together with sIL-2Rα may help to distinguish between "real" relapse and "false" sIL-2Rα increase due to G-CSF administration or CVC-related sepsis...
  33. ncbi Brain metastases in paediatric patients: characteristics of a patient series and review of the literature
    Joanna Stefanowicz
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Poland
    Folia Neuropathol 49:271-81. 2011
    ..The autopsy examination can still be helpful in the final diagnosis of certain cases with atypical clinical presentations...
  34. ncbi [Neurofibromatosis type 1 in children. Experiences of the Gdansk Paediatric Oncohaematology Centre. Preliminary results]
    Danuta Sierota
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 11:307-12. 2007
    ..The aim of the study was assessment of the most frequent symptoms on the basis of long term observation of children with NF1 and presentation of implemented diagnostic and therapeutic procedures...
  35. ncbi Childhood rhabdomyosarcoma metastatic to bone marrow presenting with disseminated intravascular coagulation and acute tumour lysis syndrome: review of the literature apropos of two cases
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, 80 211 Gdansk, Poland
    Clin Exp Metastasis 27:399-407. 2010
    ..The prognosis in children with RMS metastatic to BM with signs of DIC or ATLS at admission depends on the response to chemotherapy, however generally it is highly disappointing...
  36. ncbi Deregulated systemic IL-10/IL-12 balance in advanced and poor prognosis paediatric soft tissue sarcomas
    Ewa Bien
    Department of Paediatrics, Haematology, Oncology and Endocrinology, Medical University of Gdansk, Gdansk, Poland
    Biomarkers 18:204-15. 2013
    ..Conclusion: Serum IL-10/IL-12 balance determination may facilitate to assess risk groups and prognosis in childhood STS...
  37. ncbi [Influence of surgery and radiotherapy on growth and pubertal development in children treated for brain tumour]
    Dorota Birkholz
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku
    Med Wieku Rozwoj 9:463-9. 2005
    ..The increasing number of childhood cancer survivors has resulted in a growing interest in the late effects, which depend on type of treatment. Frequently, a brain tumour and its therapy in children are endocrinologically devastating...
  38. ncbi [Rare tumours--are they really rare in the Polish children population?]
    Anna Balcerska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademii Medycznej w Gdansku
    Przegl Lek 61:57-61. 2004
    ....
  39. ncbi [Yesterday, today and tomorrow of antiangiogenic therapy]
    Elzbieta Adamkiewicz-Drozynska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii AM w Gdansku, ul Debinki 7, 80 211 Gdansk, Poland
    Med Wieku Rozwoj 12:995-1000. 2008
    ..The first clinical studies on metronomic chemotherapy in children, as well as the trials of combined antiangiogenic therapy and metronomic chemotherapy are presented...
  40. ncbi Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT)
    Ewa Bien
    Department of Pediatrics, Medical University, Gdansk, Poland
    Eur J Cancer 47:2347-52. 2011
    ..Pancreatoblastoma is a very rare malignant tumour typically occurring in the early years of life. Due to its rarity, standardised diagnostic and therapeutic guidelines are not available for pancreatoblastoma...
  41. ncbi Expression and significance of HER family receptors in neuroblastic tumors
    Ewa Izycka-Swieszewska
    Department of Pathomorphology, Medical University of Gdansk, ul Debinki 7, 80 211 Gdansk, Poland
    Clin Exp Metastasis 28:271-82. 2011
    ..Our study showed that the role of HER family members in NT biology is interrelated and complex but their expression level may present a novel prognostic factor for NT patients outcome...
  42. ncbi [Thymoma and thymic carcinoma--review of literature and clinical characteristics based on the Polish Paediatric Solid Tumours Study Group experience]
    Teresa Stachowicz-Stencel
    Ośrodki Onkologii i Chirurgii Dzieciecej PPGGL z Gdańska, Poland
    Med Wieku Rozwoj 11:313-8. 2007
    ..4. Further detailed analysis in all the cases of thymic carcinomas in children is recommended in order to estimate the optimal strategy of treatment...
  43. ncbi [Interleukin 2 receptor--the structure, function and clinical significance in malignant diseases of adults and children]
    Ewa Bien
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii Akademii Medycznej w Gdańsku
    Postepy Hig Med Dosw 57:669-83. 2003
    ..The authors review the role and clinical usefulness of soluble IL-2R alpha in neoplasms' diagnostics, prognosis and treatment monitoring both in adult patients and in children...
  44. ncbi Sonographic diagnosis and monitoring of localized langerhans cell histiocytosis of the skull
    Wojciech Kosiak
    Department of Paediatric, Haematology, Oncology, and Endocrinology, Medical University of Gdansk, Gdansk, Poland
    J Clin Ultrasound 41:134-9. 2013
    ..The aim of the study was to investigate the role of sonography (US) in the diagnosis and monitoring of bone lesions in children with localized LCH of the skull...