Affiliation: Adam Mickiewicz University
Szczuka E, Kaznowski A, Bosacka K, Strzemieczna E. Antimicrobial resistance and presence of ileS-2 gene encoding mupirocin resistance in clinical isolates of methicillin-resistant Staphylococcus sp. Folia Microbiol (Praha). 2009;54:153-6 pubmed publisher
..aureus strains. Thirty-nine % of S. aureus strains were resistant only to beta-lactams. None of the MRSA strains carried ileS-2 gene; this gene was found in two strains of S. epidermidis. ..
Szczuka E, Grabska K, Kaznowski A. In Vitro Activity of Rifampicin Combined with Daptomycin or Tigecycline on Staphylococcus haemolyticus Biofilms. Curr Microbiol. 2015;71:184-9 pubmed publisher
..125 to 2Â Âµg/ml. These results indicated that the tigecycline/rifampicin combination was more effective against ica-independent biofilm, formed by S. haemolyticus strains, than the daptomycin/rifampicin combination. ..
Szczuka E, Krajewska M, Lijewska D, Bosacka K, Kaznowski A. Diversity of staphylococcal cassette chromosome mec elements in nosocomial multiresistant Staphylococcus haemolyticus isolates. J Appl Genet. 2016;57:543-547 pubmed
..However, ccr sequence analysis does not allow the identification of a new allotype, based on a cut-off value of 85 % identity. The ccr genes in the S. haemolitycus strain showed ?96 % sequence identity to the ccrAB2 genes. ..
Szczuka E, Krzyminska S, Bogucka N, Kaznowski A. Multifactorial mechanisms of the pathogenesis of methicillin-resistant Staphylococcus hominis isolated from bloodstream infections. Antonie Van Leeuwenhoek. 2018;111:1259-1265 pubmed publisher
..The results indicate that the pathogenicity of S. hominis may be multifactorial, involving adhesion, invasion and the activity of extracellular toxins, which cause damage to the host epithelium. ..
Szczuka E, Makowska N, Bosacka K, SÅ‚otwiÅ„ska A, Kaznowski A. Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus hominis strains isolated from clinical specimens. Folia Microbiol (Praha). 2016;61:143-7 pubmed publisher
..These studies indicated that resistance to MLSB in S. hominis is mostly based on the ribosomal target modification mechanism mediated by erm genes, mainly the erm(C), and enzymatic drug inactivation mediated by lnu(A). ..