Daniela Pohl

Summary

Publications

  1. ncbi request reprint Paediatric multiple sclerosis and acute disseminated encephalomyelitis in Germany: results of a nationwide survey
    Daniela Pohl
    Department of Paediatrics and Paediatric Neurology, Georg August University, Robert Koch Strasse 40, 37075, Gottingen, Germany
    Eur J Pediatr 166:405-12. 2007
  2. doi request reprint Epidemiology, immunopathogenesis and management of pediatric central nervous system inflammatory demyelinating conditions
    Daniela Pohl
    Children s Hospital of Eastern Switzerland, St Gallen, Switzerland
    Curr Opin Neurol 21:366-72. 2008
  3. ncbi request reprint High seroprevalence of Epstein-Barr virus in children with multiple sclerosis
    D Pohl
    Brauweg 19, 37073 Goettingen, Germany
    Neurology 67:2063-5. 2006
  4. ncbi request reprint Common infectious agents in multiple sclerosis: a case-control study in children
    Bernd Krone
    Department of Virology, Georg August University Goettingen, Germany
    Mult Scler 14:136-9. 2008
  5. ncbi request reprint Pediatric multiple sclerosis: detection of clinically silent lesions by multimodal evoked potentials
    Daniela Pohl
    Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Germany
    J Pediatr 149:125-7. 2006
  6. ncbi request reprint Tau, phospho-tau, and S-100B in the cerebrospinal fluid of children with multiple sclerosis
    Kevin Rostasy
    Department of Pediatrics and Pediatric Neurology, Georg August University, Gottingen, Germany
    J Child Neurol 20:822-5. 2005
  7. pmc Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
    Kevin C O'Connor
    Center for Neurologic Diseases, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA
    Nat Med 13:211-7. 2007
  8. ncbi request reprint Differential diagnosis and evaluation in pediatric multiple sclerosis
    Jin S Hahn
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA
    Neurology 68:S13-22. 2007
  9. ncbi request reprint Treatment of early onset multiple sclerosis with subcutaneous interferon beta-1a
    Daniela Pohl
    Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Robert Koch Strasse 40, 37075 Germany E mail
    Neurology 64:888-90. 2005
  10. ncbi request reprint Diagnosing paediatric multiple sclerosis versus acute disseminated encephalomyelitis
    Daniela Pohl
    Dev Med Child Neurol 49:884. 2007

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Paediatric multiple sclerosis and acute disseminated encephalomyelitis in Germany: results of a nationwide survey
    Daniela Pohl
    Department of Paediatrics and Paediatric Neurology, Georg August University, Robert Koch Strasse 40, 37075, Gottingen, Germany
    Eur J Pediatr 166:405-12. 2007
    ..With an estimated minimum of 50 new cases per year, the incidence of paediatric MS in Germany is much more frequent than previously believed...
  2. doi request reprint Epidemiology, immunopathogenesis and management of pediatric central nervous system inflammatory demyelinating conditions
    Daniela Pohl
    Children s Hospital of Eastern Switzerland, St Gallen, Switzerland
    Curr Opin Neurol 21:366-72. 2008
    ..This review discusses characteristics of these disorders with focus on epidemiology and treatment of acute disseminated encephalomyelitis, neuromyelitis optica and multiple sclerosis...
  3. ncbi request reprint High seroprevalence of Epstein-Barr virus in children with multiple sclerosis
    D Pohl
    Brauweg 19, 37073 Goettingen, Germany
    Neurology 67:2063-5. 2006
    ..6% vs 72.1% in controls, p = 0.001) but did not display serologic evidence for a recent EBV infection. EBV antibody concentrations of pediatric patients with MS were significantly higher vs controls...
  4. ncbi request reprint Common infectious agents in multiple sclerosis: a case-control study in children
    Bernd Krone
    Department of Virology, Georg August University Goettingen, Germany
    Mult Scler 14:136-9. 2008
    ..Additional investigations, however, make it highly unlikely that a relevant number of children have experienced infections with HSV-2. In general this study supports and emphasizes a complex infectious and immunologic background of MS...
  5. ncbi request reprint Pediatric multiple sclerosis: detection of clinically silent lesions by multimodal evoked potentials
    Daniela Pohl
    Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Germany
    J Pediatr 149:125-7. 2006
    ..In 46% of 85 childhood patients with MS, spatial dissemination was detected by EP before the second clinical attack. EP may constitute an important tool for earlier diagnosis of pediatric MS...
  6. ncbi request reprint Tau, phospho-tau, and S-100B in the cerebrospinal fluid of children with multiple sclerosis
    Kevin Rostasy
    Department of Pediatrics and Pediatric Neurology, Georg August University, Gottingen, Germany
    J Child Neurol 20:822-5. 2005
    ..These data indicate that axonal injury is not restricted to adult multiple sclerosis but can already occur in children with multiple sclerosis...
  7. pmc Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
    Kevin C O'Connor
    Center for Neurologic Diseases, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA
    Nat Med 13:211-7. 2007
    ..MOG-specific autoantibodies were identified in a subset of ADEM but only rarely in adult-onset MS cases, indicating that MOG is a more prominent target antigen in ADEM than MS...
  8. ncbi request reprint Differential diagnosis and evaluation in pediatric multiple sclerosis
    Jin S Hahn
    Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA
    Neurology 68:S13-22. 2007
    ..The evaluation is determined by the clinical and neuroradiologic presentation. A minimal diagnostic battery is proposed. More expanded evaluations are indicated for specific or atypical clinical presentations...
  9. ncbi request reprint Treatment of early onset multiple sclerosis with subcutaneous interferon beta-1a
    Daniela Pohl
    Department of Pediatrics and Pediatric Neurology, Georg August University Goettingen, Robert Koch Strasse 40, 37075 Germany E mail
    Neurology 64:888-90. 2005
    ..Laboratory abnormalities included asymptomatic leukopenia (27%) and elevated hepatic transaminases (35%). Treatment with IFNbeta-1a was safe and well tolerated in the majority of children and adolescents...
  10. ncbi request reprint Diagnosing paediatric multiple sclerosis versus acute disseminated encephalomyelitis
    Daniela Pohl
    Dev Med Child Neurol 49:884. 2007
  11. ncbi request reprint Myelin oligodendrocyte gene polymorphisms and childhood multiple sclerosis
    Andreas Ohlenbusch
    Abteilung P├Ądiatrie, Schwerpunkt Neuropadiatrie, Georg August Universitat, 37075 Gottingen, Germany
    Pediatr Res 52:175-9. 2002
    ..A putative C1q binding site in the C"-D loop of the Ig superfamily motif encompasses R66. In conclusion, the polymorphisms observed do not provide evidence to support a significant role for MOG in multiple sclerosis susceptibility...