Sylvain Pitre

Summary

Publications

  1. pmc PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs
    Sylvain Pitre
    School of Computer Science, Carleton University, Ottawa, Canada
    BMC Bioinformatics 7:365. 2006
  2. pmc Binding site prediction for protein-protein interactions and novel motif discovery using re-occurring polypeptide sequences
    Adam Amos-Binks
    School of Computer Science, Carleton University, Ottawa, ON K1S5B6, Canada
    BMC Bioinformatics 12:225. 2011
  3. pmc Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae
    Katayoun Omidi
    Department of Biology, Carleton University, Ottawa, Ontario, Canada Ottawa Institute of Systems Biology, Carleton University, Ottawa, Ontario, Canada
    PLoS ONE 9:e87248. 2014
  4. ncbi request reprint Recent advances in protein-protein interaction prediction: experimental and computational methods
    Matthew Jessulat
    Carleton University, Department of Biology, 209 Nesbitt Building, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada
    Expert Opin Drug Discov 6:921-35. 2011
  5. pmc Computational approaches toward the design of pools for the in vitro selection of complex aptamers
    Xuemei Luo
    School of Computer Science, Carleton University, Ottawa, Ontario K1S5B6, Canada
    RNA 16:2252-62. 2010
  6. ncbi request reprint Computational methods for predicting protein-protein interactions
    Sylvain Pitre
    School of Computer Science, Carleton University, 5304 Herzberg Building, 1125 Colonel By Drive, K1S 5B6, Ottawa, Ontario, Canada
    Adv Biochem Eng Biotechnol 110:247-67. 2008

Collaborators

Detail Information

Publications6

  1. pmc PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs
    Sylvain Pitre
    School of Computer Science, Carleton University, Ottawa, Canada
    BMC Bioinformatics 7:365. 2006
    ..Consequently there is a growing need for the development of computational tools that are capable of effectively identifying such interactions...
  2. pmc Binding site prediction for protein-protein interactions and novel motif discovery using re-occurring polypeptide sequences
    Adam Amos-Binks
    School of Computer Science, Carleton University, Ottawa, ON K1S5B6, Canada
    BMC Bioinformatics 12:225. 2011
    ..PIPE-Sites operates at high specificity and requires only the sequences of query proteins and a database of known binary interactions with no binding site data, making it applicable to binding site prediction at the proteome-scale...
  3. pmc Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae
    Katayoun Omidi
    Department of Biology, Carleton University, Ottawa, Ontario, Canada Ottawa Institute of Systems Biology, Carleton University, Ottawa, Ontario, Canada
    PLoS ONE 9:e87248. 2014
    ..Collectively, we report that the activity of Pph3p and Psy2p further connects NHEJ repair to cell cycle progression. ..
  4. ncbi request reprint Recent advances in protein-protein interaction prediction: experimental and computational methods
    Matthew Jessulat
    Carleton University, Department of Biology, 209 Nesbitt Building, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada
    Expert Opin Drug Discov 6:921-35. 2011
    ..We expect to see a growing number of similar techniques capable of large-scale PPI predictions...
  5. pmc Computational approaches toward the design of pools for the in vitro selection of complex aptamers
    Xuemei Luo
    School of Computer Science, Carleton University, Ottawa, Ontario K1S5B6, Canada
    RNA 16:2252-62. 2010
    ..We show that using our computationally designed DNA pool greatly improves access to highly complex sequence structures for SELEX experiments (without losing our ability to select for common one-way and two-way junction sequences)...
  6. ncbi request reprint Computational methods for predicting protein-protein interactions
    Sylvain Pitre
    School of Computer Science, Carleton University, 5304 Herzberg Building, 1125 Colonel By Drive, K1S 5B6, Ottawa, Ontario, Canada
    Adv Biochem Eng Biotechnol 110:247-67. 2008
    ..For comparison, the conventional large-scale approaches to predict PPIs are also briefly discussed. The chapter concludes with a discussion of the limitations of both experimental and computational methods of determining PPIs...