T Pincus

Summary

Publications

  1. ncbi request reprint RAPID3-an index of physical function, pain, and global status as "vital signs" to improve care for people with chronic rheumatic diseases
    Theodore Pincus
    New York University School of Medicine, New York, NY, USA
    Bull NYU Hosp Jt Dis 67:211-25. 2009
  2. pmc Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, Finland
    Arthritis Res Ther 12:R42. 2010
  3. doi request reprint Decline of mean initial prednisone dosage from 10.3 to 3.6 mg/day to treat rheumatoid arthritis between 1980 and 2004 in one clinical setting, with long-term effectiveness of dosages less than 5 mg/day
    Theodore Pincus
    Department of Rheumatology, Room 1608, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Arthritis Care Res (Hoboken) 65:729-36. 2013
  4. ncbi request reprint Pragmatic and scientific advantages of MDHAQ/ RAPID3 completion by all patients at all visits in routine clinical care
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Bull NYU Hosp Jt Dis 70:30-6. 2012
  5. ncbi request reprint MDHAQ/RAPID3 can provide a roadmap or agenda for all rheumatology visits when the entire MDHAQ is completed at all patient visits and reviewed by the doctor before the encounter
    Theodore Pincus
    Division of Rheumatology, NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, New York 10003, USA
    Bull NYU Hosp Jt Dis 70:177-86. 2012
  6. ncbi request reprint Treat-to-target: not as simple as it appears
    Theodore Pincus
    Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 1003, USA
    Clin Exp Rheumatol 30:S10-20. 2012
  7. ncbi request reprint An evidence-based medical visit for patients with rheumatoid arthritis based on standard, quantitative scientific data from a patient MDHAQ and physician report
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, New York 100003, USA
    Bull NYU Hosp Jt Dis 70:73-94. 2012
  8. pmc Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study
    Antonio Naranjo
    Hospital de Gran Canaria Dr, Negrin, University of Las Palmas de Gran Canaria, Barranco de la Ballena s n 35011, Spain
    Arthritis Res Ther 10:R30. 2008
  9. pmc Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA study
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, and Medcare Oy, Hämeentie 1, 44100 Aanekoski, Finland
    Arthritis Res Ther 11:R7. 2009
  10. ncbi request reprint Are excellent systematic reviews of clinical trials useful for patient care?
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Nat Clin Pract Rheumatol 4:294-5. 2008

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint RAPID3-an index of physical function, pain, and global status as "vital signs" to improve care for people with chronic rheumatic diseases
    Theodore Pincus
    New York University School of Medicine, New York, NY, USA
    Bull NYU Hosp Jt Dis 67:211-25. 2009
    ..RAPID3 vital signs can contribute to this synthesis toward improved quality, outcomes, and documentation of rheumatology care...
  2. pmc Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, Finland
    Arthritis Res Ther 12:R42. 2010
    ..Recent reports suggest that the use of biologic agents offers potential for reduced work disability rates, but the conclusions are based on surrogate disease activity measures derived from studies primarily from Western countries...
  3. doi request reprint Decline of mean initial prednisone dosage from 10.3 to 3.6 mg/day to treat rheumatoid arthritis between 1980 and 2004 in one clinical setting, with long-term effectiveness of dosages less than 5 mg/day
    Theodore Pincus
    Department of Rheumatology, Room 1608, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Arthritis Care Res (Hoboken) 65:729-36. 2013
    ..To analyze prednisone treatment from 1980-2004 in 308 patients with rheumatoid arthritis (RA), including 75 monitored over 4-8 years and 73 monitored over >8 years, for initial dose, long-term doses and effectiveness, and adverse events...
  4. ncbi request reprint Pragmatic and scientific advantages of MDHAQ/ RAPID3 completion by all patients at all visits in routine clinical care
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Bull NYU Hosp Jt Dis 70:30-6. 2012
    ..All rheumatologists may include MDHAQ/RAPID3 in all patients in the infrastructure of clinical care...
  5. ncbi request reprint MDHAQ/RAPID3 can provide a roadmap or agenda for all rheumatology visits when the entire MDHAQ is completed at all patient visits and reviewed by the doctor before the encounter
    Theodore Pincus
    Division of Rheumatology, NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, New York 10003, USA
    Bull NYU Hosp Jt Dis 70:177-86. 2012
    ....
  6. ncbi request reprint Treat-to-target: not as simple as it appears
    Theodore Pincus
    Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 1003, USA
    Clin Exp Rheumatol 30:S10-20. 2012
    ....
  7. ncbi request reprint An evidence-based medical visit for patients with rheumatoid arthritis based on standard, quantitative scientific data from a patient MDHAQ and physician report
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, New York 100003, USA
    Bull NYU Hosp Jt Dis 70:73-94. 2012
    ..Quantitative data from patients and doctors on an evidence-based visit can advance rheumatology clinical care and clinical science...
  8. pmc Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study
    Antonio Naranjo
    Hospital de Gran Canaria Dr, Negrin, University of Las Palmas de Gran Canaria, Barranco de la Ballena s n 35011, Spain
    Arthritis Res Ther 10:R30. 2008
    ....
  9. pmc Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA study
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, and Medcare Oy, Hämeentie 1, 44100 Aanekoski, Finland
    Arthritis Res Ther 11:R7. 2009
    ....
  10. ncbi request reprint Are excellent systematic reviews of clinical trials useful for patient care?
    Theodore Pincus
    Department of Medicine, Division of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Nat Clin Pract Rheumatol 4:294-5. 2008
  11. pmc Efficacy of prednisone 1-4 mg/day in patients with rheumatoid arthritis: a randomised, double-blind, placebo controlled withdrawal clinical trial
    T Pincus
    Department of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Ann Rheum Dis 68:1715-20. 2009
    ....
  12. ncbi request reprint Can RAPID3, an index without formal joint counts or laboratory tests, serve to guide rheumatologists in tight control of rheumatoid arthritis in usual clinical care?
    Theodore Pincus
    New York University School of Medicine, New York, NY 10003, USA
    Bull NYU Hosp Jt Dis 67:254-66. 2009
    ..RAPID3 provides a feasible, informative quantitative index for busy clinical settings...
  13. doi request reprint Patient questionnaires in rheumatoid arthritis: advantages and limitations as a quantitative, standardized scientific medical history
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:735-43, vii. 2009
    ..Patient questionnaires are useful to monitor patient status in usual clinical care, with almost no effort on the part of the physician and staff if distributed by the receptionist in the infrastructure of office practice...
  14. doi request reprint RAPID3, an index to assess and monitor patients with rheumatoid arthritis, without formal joint counts: similar results to DAS28 and CDAI in clinical trials and clinical care
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:773-8, viii. 2009
    ..In all rheumatic diseases RAPID3 is able to provide a baseline quantitative value, and to quantitatively monitor and document improvement or worsening over time...
  15. doi request reprint Complex measures and indices for clinical research compared with simple patient questionnaires to assess function, pain, and global estimates as rheumatology "vital signs" for usual clinical care
    Theodore Pincus
    Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East, 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:779-86, ix. 2009
    ..Differences between complex measures for research and simple questionnaires designed for usual clinical care might be more widely recognized, to promote quantitative measurement in the infrastructure of usual rheumatology care...
  16. doi request reprint The HAQ compared with the MDHAQ: "keep it simple, stupid" (KISS), with feasibility and clinical value as primary criteria for patient questionnaires in usual clinical care
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:787-98, ix. 2009
    ..Both the HAQ and MDHAQ involve 2 sides of one sheet of paper, and are completed by patients in 5 to 10 minutes. The HAQ requires 42 seconds to score, compared with 5 to 10 seconds for RAPID3 on the MDHAQ...
  17. ncbi request reprint Should an order to "monitor long-term vital signs," including mortality outcomes, be as routine as an order for a laboratory test in patients with rheumatic diseases?
    T Pincus
    New York University School of Medicine, New York, USA
    Clin Exp Rheumatol 26:S21-4. 2008
    ....
  18. ncbi request reprint Limitations of a quantitative swollen and tender joint count to assess and monitor patients with rheumatoid arthritis
    Theodore Pincus
    New York University School of Medicine, New York, NY, USA
    Bull NYU Hosp Jt Dis 66:216-23. 2008
    ..It may be suggested that a careful qualitative joint count, supplemented by quantitative patient self-report questionnaire scores, may be more than adequate to monitor and document changes in patient status in busy clinical settings...
  19. ncbi request reprint Can a Multi-Dimensional Health Assessment Questionnaire (MDHAQ) and Routine Assessment of Patient Index Data (RAPID) scores be informative in patients with all rheumatic diseases?
    Theodore Pincus
    NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
    Best Pract Res Clin Rheumatol 21:733-53. 2007
    ....
  20. ncbi request reprint A three-page Standard Protocol to Evaluate Rheumatoid Arthritis (SPERA) for efficient capture of essential data from patients and health professionals in standard clinical care and clinical research
    Theodore Pincus
    NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
    Best Pract Res Clin Rheumatol 21:677-85. 2007
    ..The SPERA is presented not as an optimal format but rather as an example of a possible approach to develop a common format for core clinical data to be collected in standard clinical care...
  21. ncbi request reprint Quantitative measures of rheumatic diseases for clinical research versus standard clinical care: differences, advantages and limitations
    Theodore Pincus
    NYU Hospital for Joint Diseases, New York, NY 10003, USA
    Best Pract Res Clin Rheumatol 21:601-28. 2007
    ..More attention to measures for use in standard care could improve care and outcomes for patients with rheumatic diseases...
  22. ncbi request reprint A proposed continuous quality improvement approach to assessment and management of patients with rheumatoid arthritis without formal joint counts, based on quantitative routine assessment of patient index data (RAPID) scores on a multidimensional health a
    Theodore Pincus
    NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
    Best Pract Res Clin Rheumatol 21:789-804. 2007
    ..01-2), 'moderate severity' (2.01-4), and 'high severity' (>4). RAPID scoring is feasible in standard clinical care to support continuous quality improvement...
  23. ncbi request reprint Patient questionnaires and formal education as more significant prognostic markers than radiographs or laboratory tests for rheumatoid arthritis mortality--limitations of a biomedical model to predict long-term outcomes
    Theodore Pincus
    NYU Hospital for Joint Diseases, New York, 301 East 17th Street, New York, New York 10003, USA
    Bull NYU Hosp Jt Dis 65:S29-36. 2007
  24. ncbi request reprint Quantitative measurement of patient status in the regular care of patients with rheumatic diseases over 25 years as a continuous quality improvement activity, rather than traditional research
    T Pincus
    New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 25:69-81. 2007
    ..The latter cycles remain under study as ongoing CQI activities...
  25. doi request reprint An index of only patient-reported outcome measures, routine assessment of patient index data 3 (RAPID3), in two abatacept clinical trials: similar results to disease activity score (DAS28) and other RAPID indices that include physician-reported measures
    T Pincus
    NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Rheumatology (Oxford) 47:345-9. 2008
    ....
  26. ncbi request reprint Pain, function, and RAPID scores: vital signs in chronic diseases, analogous to pulse and temperature in acute diseases and blood pressure and cholesterol in long-term health
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, NYU Medical Center, New York, NY, USA
    Bull NYU Hosp Jt Dis 66:155-65. 2008
    ....
  27. ncbi request reprint Visual analog scales in formats other than a 10 centimeter horizontal line to assess pain and other clinical data
    Theodore Pincus
    NYU Hospital for Joint Diseases, New York, New York 10003, USA
    J Rheumatol 35:1550-8. 2008
    ....
  28. ncbi request reprint RAPID3 (Routine Assessment of Patient Index Data 3), a rheumatoid arthritis index without formal joint counts for routine care: proposed severity categories compared to disease activity score and clinical disease activity index categories
    Theodore Pincus
    New York University Hospital for Joint Diseases, New York, New York 10003, USA
    J Rheumatol 35:2136-47. 2008
    ....
  29. doi request reprint How to collect an MDHAQ to provide rheumatology vital signs (function, pain, global status, and RAPID3 scores) in the infrastructure of rheumatology care, including some misconceptions regarding the MDHAQ
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York University School of Medicine, New York, NY, USA
    Rheum Dis Clin North Am 35:799-812, x. 2009
    ..Patient questionnaires designed for usual clinical care, such as the MDHAQ, save time and improve the quality and documentation of the visit for the patient and the physician...
  30. doi request reprint Quantitative recording of physician clinical estimates, beyond a global estimate and formal joint count, in usual care: applying the scientific method, using a simple one-page worksheet
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:813-7, x. 2009
    ..All changes in medications are recorded. A template is available for a formal 42 joint count. The worksheet requires fewer than 15 seconds and has proven of considerable value in clinical care...
  31. doi request reprint Clues on the MDHAQ to identify patients with fibromyalgia and similar chronic pain conditions
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:865-9, xii. 2009
    ..Data from the MDHAQ provide clues to the presence of fibromyalgia/chronic pain conditions, including patients with inflammatory diseases who also have concomitant fibromyalgia/chronic pain conditions...
  32. doi request reprint RAPID3 (Routine Assessment of Patient Index Data) on an MDHAQ (Multidimensional Health Assessment Questionnaire): agreement with DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index) activity categories, scored in five versus more than
    Theodore Pincus
    New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Arthritis Care Res (Hoboken) 62:181-9. 2010
    ....
  33. ncbi request reprint Are patient questionnaire scores as "scientific" as laboratory tests for rheumatology clinical care?
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, NYU Langone Medical Center, New York, New York 10003, USA
    Bull NYU Hosp Jt Dis 68:130-9. 2010
    ..Advances in therapy require laboratory science, but patient questionnaires provide optimal "scientific" data for clinical care...
  34. ncbi request reprint Beyond RAPID3 - practical use of the MDHAQ to improve doctor-patient communication
    Theodore Pincus
    New York University School of Medicine, New York, NY, USA
    Bull NYU Hosp Jt Dis 68:223-31. 2010
    ..routine Assessment of Patient Index Data 3 (RAPID3) scores are recorded in the medical record and entered into a flowsheet, which also includes other MDHAQ scores, laboratory tests, and medications...
  35. ncbi request reprint Underestimation of the efficacy, effectiveness, tolerability, and safety of weekly low-dose methotrexate in information presented to physicians and patients
    T Pincus
    Department of Medicine, Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 28:S68-79. 2010
    ....
  36. doi request reprint RAPID3 (Routine Assessment of Patient Index Data 3) severity categories and response criteria: Similar results to DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index) in the RAPID 1 (Rheumatoid Arthritis Prevention of Structural Damag
    Theodore Pincus
    New York University School of Medicine and New York University Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Arthritis Care Res (Hoboken) 63:1142-9. 2011
    ....
  37. ncbi request reprint The clinical efficacy of 3 mg/day prednisone in patients with rheumatoid arthritis: evidence from a randomized, double-blind, placebo-controlled withdrawal clinical trial
    T Pincus
    Department of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 29:S73-6. 2011
    ..No meaningful adverse events were reported, as anticipated. These data document statistically significant differences between the efficacy of 1-4 mg prednisone vs. placebo in only 31 patients, which may suggest a robust treatment effect...
  38. ncbi request reprint Long-term prednisone in doses of less than 5 mg/day for treatment of rheumatoid arthritis: personal experience over 25 years
    T Pincus
    Department of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 29:S130-8. 2011
    ..Further clinical trials and long-term observational studies are needed to develop optimal treatment strategies for patients with RA with low-dose prednisone...
  39. doi request reprint Proposed severity and response criteria for Routine Assessment of Patient Index Data (RAPID3): results for categories of disease activity and response criteria in abatacept clinical trials
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    J Rheumatol 38:2565-71. 2011
    ..RAPID3 is correlated significantly with DAS28, but calculated in 5-10 seconds on a Multidimensional Health Assessment Questionnaire (MDHAQ), compared to 114 seconds for DAS28...
  40. doi request reprint Laboratory tests to assess patients with rheumatoid arthritis: advantages and limitations
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:731-4, vi-vii. 2009
    ..Physicians and patients would benefit from an improved understanding of the limitations of laboratory tests in diagnosis and management of patients with RA...
  41. doi request reprint Criterion contamination of depression scales in patients with rheumatoid arthritis: the need for interpretation of patient questionnaires (as all clinical measures) in the context of all information about the patient
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York University School of Medicine, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:861-4, xi-xii. 2009
    ..The BDI was revised in 1996, as the Beck Depression Inventory-II (BDI-II), to eliminate the items reflecting somatic disease...
  42. doi request reprint Quality control of a medical history: improving accuracy with patient participation, supported by a four-page version of the multidimensional health assessment questionnaire (MDHAQ)
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:851-60, xi. 2009
    ..This procedure engenders a more accurate patient history with no effort on the part of the physician, saving time for the physician and improving the quality of the medical record...
  43. doi request reprint Flowsheets that include MDHAQ physical function, pain, global, and RAPID3 scores, laboratory tests, and medications to monitor patients with all rheumatic diseases: an electronic database for an electronic medical record
    Theodore Pincus
    Division of Rheumatology, NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:829-42, x-xi. 2009
    ..Flowsheets are presented for patients with rheumatologic diagnoses other than rheumatoid arthritis to illustrate the value of the multidimensional health assessment questionnaire and RAPID3 scores in an electronic database for an EMR...
  44. doi request reprint A multi-dimensional health assessment questionnaire (MDHAQ) and routine assessment of patient index data (RAPID3) scores are informative in patients with all rheumatic diseases
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:819-27, x. 2009
    ..The MDHAQ is useful in rheumatic diseases, to improve management documentation and outcomes. MDHAQ data for physical function, pain, global status, and RAPID3 scores appear preferable to no quantitative data...
  45. doi request reprint Complexities in assessment of rheumatoid arthritis: absence of a single gold standard measure
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:687-97, v. 2009
    ..Further elucidation of these differences may be informative in efforts to advance quantitative scientific patient assessment and management in rheumatic diseases, with improved patient outcomes...
  46. doi request reprint A Standard Protocol to Evaluate Rheumatoid Arthritis (SPERA) for efficient capture of essential data from a patient and a health professional in a uniform "scientific" format
    Theodore Pincus
    Division of Rheumatology, Department of Medicine, NYU Hospital for Joint Diseases, New York University School of Medicine, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:843-50, xi. 2009
    ..The SPERA is presented as an example of a possible approach to develop a uniform common format for collecting core data in usual clinical care...
  47. ncbi request reprint A proposed approach to recognise "near-remission" quantitatively without formal joint counts or laboratory tests: a patient self-report questionnaire routine assessment of patient index data (RAPID) score as a guide to a "continuous quality
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 24:S-60-5; quiz S-66-73. 2006
    ....
  48. ncbi request reprint An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in
    T Pincus
    Division of Rheumatology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Arthritis Rheum 48:625-30. 2003
    ....
  49. pmc Work disability in early rheumatoid arthritis: higher rates but better clinical status in Finland compared with the US
    C P Chung
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 4500, USA
    Ann Rheum Dis 65:1653-7. 2006
    ..To analyse and compare work disability attributed to rheumatoid arthritis in two cohorts of patients with early disease: one in the US and the other in Finland...
  50. pmc Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities
    Y Yazici
    Brooklyn Heights Arthritis Associates, Long Island College Hospital, Brooklyn, NY, USA
    Ann Rheum Dis 64:207-11. 2005
    ..To analyse patients with rheumatoid arthritis, treated with methotrexate in a weekly academic rheumatology clinic over 13 years, for continuation of courses and reasons for discontinuation...
  51. ncbi request reprint A proposed 30-45 minute 4 page standard protocol to evaluate rheumatoid arthritis (SPERA) that includes measures of inflammatory activity, joint damage, and longterm outcomes
    T Pincus
    Vanderbilt University School of Medicine, Department of Medicine, Nashville, TN 37232 4500, USA
    J Rheumatol 26:473-80. 1999
    ..The SPERA is feasible to acquire most known relevant measures of activity, damage, and outcomes in RA in 30-45 min in usual clinical settings, to provide a complete database for analyses of longterm outcomes...
  52. ncbi request reprint Relative versus absolute goals of therapies for RA: ACR 20 or ACR 50 responses versus target values for "near remission" of DAS or single measures
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    Clin Exp Rheumatol 22:S50-6. 2004
    ..These findings suggest that absolute targets, including remission, may be realistic contemporary goals, with aggressive treatment strategies and more effective DMARDs and biologic agents...
  53. ncbi request reprint A 3-page standard protocol to evaluate rheumatoid arthritis (SPERA): efficient capture of essential data for clinical trials and observational studies
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S114-9. 2005
    ....
  54. pmc Are American College of Rheumatology 50% response criteria superior to 20% criteria in distinguishing active aggressive treatment in rheumatoid arthritis clinical trials reported since 1997? A meta-analysis of discriminant capacities
    C P Chung
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee 37232 4500, USA
    Ann Rheum Dis 65:1602-7. 2006
    ....
  55. ncbi request reprint Quantitative documentation of benefit/risk of new therapies for rheumatoid arthritis: patient questionnaires as an optimal measure in standard care
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    Clin Exp Rheumatol 22:S26-33. 2004
    ..We suggest that quantitative measurement may be incorporated into standard clinical care most easily and effectively by asking each patient to complete a simple 1-page questionnaire at each visit to a rheumatologist...
  56. ncbi request reprint Rheumatology function tests: quantitative physical measures to monitor morbidity and predict mortality in patients with rheumatic diseases
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S85-9. 2005
    ..Physical measures of function also were significant predictors of mortality in two cohorts of patients with RA, one monitored between 1973 and 1988, and a second between 1985 and 1990...
  57. ncbi request reprint Partial control of Core Data Set measures and Disease Activity Score (DAS) measures of inflammation does not prevent long-term joint damage: evidence from longitudinal observations over 5-20 years
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    Clin Exp Rheumatol 20:S42-7. 2002
    ....
  58. ncbi request reprint A practical guide to scoring a Multi-Dimensional Health Assessment Questionnaire (MDHAQ) and Routine Assessment of Patient Index Data (RAPID) scores in 10-20 seconds for use in standard clinical care, without rulers, calculators, websites or computers
    Theodore Pincus
    NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
    Best Pract Res Clin Rheumatol 21:755-87. 2007
    ..This chapter provides a brief tutorial designed to instruct rheumatologists and their staffs regarding how to use and score the MDHAQ and RAPID in standard clinical care...
  59. ncbi request reprint Time to score quantitative rheumatoid arthritis measures: 28-Joint Count, Disease Activity Score, Health Assessment Questionnaire (HAQ), Multidimensional HAQ (MDHAQ), and Routine Assessment of Patient Index Data (RAPID) scores
    Yusuf Yazici
    New York University Hospital for Joint Diseases, New York, New York 10003, USA
    J Rheumatol 35:603-9. 2008
    ..The measures studied were a 28-Joint Count, Disease Activity Score (DAS), Health Assessment Questionnaire (HAQ), Multidimensional HAQ (MDHAQ), and various Routine Assessment of Patient Index Data (RAPID) scores derived from the MDHAQ...
  60. ncbi request reprint Morning stiffness in patients with early rheumatoid arthritis is associated more strongly with functional disability than with joint swelling and erythrocyte sedimentation rate
    Yusuf Yazici
    Brooklyn Heights Arthritis Associates, Long Island College Hospital, Brooklyn, New York, USA
    J Rheumatol 31:1723-6. 2004
    ..To compare the level of morning stiffness in a cohort of patients with early rheumatoid arthritis (RA), assessed on a self-report questionnaire, to levels of patient self-report scores and clinical and laboratory variables...
  61. ncbi request reprint Complexities in the quantitative assessment of patients with rheumatic diseases in clinical trials and clinical care
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S1-9. 2005
    ....
  62. ncbi request reprint Benefit/risk of therapies for rheumatoid arthritis: underestimation of the "side effects" or risks of RA leads to underestimation of the benefit/risk of therapies
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    Clin Exp Rheumatol 22:S2-11. 2004
    ..It appears that the benefit/risk ratio of therapies for RA has increased substantially over the last two decades, and the outlook for patients with RA is much better at this time than in previous years...
  63. ncbi request reprint Relative efficiencies of physician/assessor global estimates and patient questionnaire measures are similar to or greater than joint counts to distinguish adalimumab from control treatments in rheumatoid arthritis clinical trials
    Theodore Pincus
    New York University Hospital for Joint Diseases, New York, New York 10003, USA
    J Rheumatol 35:201-5. 2008
    ..To estimate relative efficiencies of the 7 rheumatoid arthritis (RA) Core Data Set measures to distinguish adalimumab from control treatments in 4 clinical trials...
  64. ncbi request reprint Patient questionnaires and formal education level as prospective predictors of mortality over 10 years in 97% of 1416 patients with rheumatoid arthritis from 15 United States private practices
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 4500, USA
    J Rheumatol 31:229-34. 2004
    ....
  65. ncbi request reprint Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, 203 Oxford House, Nashville, TN 37232 4500, USA
    Rheumatology (Oxford) 41:1346-56. 2002
    ..Documentation of improved long-term outcomes requires long-term observational data over 5-20 yr to supplement data from randomized controlled clinical trials over 6-24 months...
  66. doi request reprint A biopsychosocial model to complement a biomedical model: patient questionnaire data and socioeconomic status usually are more significant than laboratory tests and imaging studies in prognosis of rheumatoid arthritis
    Lauren McCollum
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and NYU Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:699-712, v. 2009
    ..Socioeconomic status may be regarded as a surrogate for the importance of patient actions, in addition to actions of health professionals, in the course and outcomes of rheumatic and other chronic diseases...
  67. doi request reprint Declines in erythrocyte sedimentation rates in patients with rheumatoid arthritis over the second half of the 20th century
    Benjamin Abelson
    NYU Hospital for Joint Diseases, New York, NY, USA
    J Rheumatol 36:1596-9. 2009
    ....
  68. ncbi request reprint Clinical evidence for osteoarthritis as an inflammatory disease
    T Pincus
    Division of Rheumatology, Vanderbilt University Medical Center, 203 Oxford House, Box 5, Nashville, TN 37232-4500, USA
    Curr Rheumatol Rep 3:524-34. 2001
    ..A recent crossover clinical trial indicated significantly greater efficacy of the NSAID, diclofenac/misoprostol, versus acetaminophen for most patients with OA...
  69. ncbi request reprint A multidimensional health assessment questionnaire (MDHAQ) for all patients with rheumatic diseases to complete at all visits in standard clinical care
    Theodore Pincus
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Bull NYU Hosp Jt Dis 65:150-60. 2007
    ..The MDHAQ is useful in all rheumatic diseases by saving time, documenting changes in status over long periods, and by improving rheumatology care and outcomes...
  70. doi request reprint Radiographic measures to assess patients with rheumatoid arthritis: advantages and limitations
    Yusuf Yazici
    Division of Rheumatology, Department of Medicine, New York University School of Medicine and New York University Hospital for Joint Diseases, Room 1608, 301 East 17th Street, New York, NY 10003, USA
    Rheum Dis Clin North Am 35:723-9, vi. 2009
    ..Whereas prevention of radiographic progression is certainly desirable, it appears that prevention of functional disability is far more important for successful patient outcomes...
  71. pmc Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and coronary atherosclerosis in patients with rheumatoid arthritis
    Cecilia P Chung
    Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232 6602, USA
    J Rheumatol 37:1633-8. 2010
    ....
  72. ncbi request reprint Advantages and limitations of quantitative measures to assess rheumatoid arthritis: joint counts, radiographs, laboratory tests, and patient questionnaires
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    Bull NYU Hosp Jt Dis 64:32-9. 2006
    ..A multidimensional health assessment questionnaire is useful in all rheumatic diseases, with scoring templates and medical history information to save time for the rheumatologist and patient in standard care...
  73. ncbi request reprint Quantitative measures for assessing rheumatoid arthritis in clinical trials and clinical care
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Best Pract Res Clin Rheumatol 17:753-81. 2003
    ..The most simple and effective method of collecting important long-term data from patients in routine clinical care is through patient self-report questionnaires...
  74. pmc Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis
    Cecilia P Chung
    Department of Medicine, Vanderbilt University School of Medicine, 1161 21st Ave, Nashville, TN 37232, USA
    Arthritis Res Ther 8:R186. 2006
    ..15, 95% CI 1.02 to 1.29, P = 0.03). In conclusion, a higher Framingham risk score is independently associated with the presence of coronary calcification in patients with RA...
  75. ncbi request reprint Increased augmentation index in rheumatoid arthritis and its relationship to coronary artery atherosclerosis
    Ingrid Avalos
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2681, USA
    J Rheumatol 34:2388-94. 2007
    ..We examined the hypothesis that augmentation index and pulse wave velocity are increased in RA, and are related to coronary artery atherosclerosis...
  76. doi request reprint Quantitative data for care of patients with systemic lupus erythematosus in usual clinical settings: a patient Multidimensional Health Assessment Questionnaire and physician estimate of noninflammatory symptoms
    Anca Dinu Askanase
    Department of Medicine, Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    J Rheumatol 38:1309-16. 2011
    ....
  77. ncbi request reprint Clinical trials in rheumatic diseases: designs and limitations
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Rheum Dis Clin North Am 30:701-24, v-vi. 2004
    ..Therefore, long-term databases are needed to supplement clinical trials in analyzing results of therapy for rheumatoid arthritis...
  78. ncbi request reprint Quantitative measures and indices to assess rheumatoid arthritis in clinical trials and clinical care
    Theodore Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Rheum Dis Clin North Am 30:725-51, vi. 2004
    ..Therefore, the measures have been combined into pooled indices that can be applied to individual patients in clinical research and clinical care...
  79. ncbi request reprint Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosis
    Cecilia P Chung
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 6602, USA
    Atherosclerosis 196:756-63. 2008
    ..In conclusion, patients with RA have a higher prevalence of the metabolic syndrome than control subjects. Inflammation-associated metabolic syndrome is a mechanism that may contribute to increased coronary-artery atherosclerosis in RA...
  80. ncbi request reprint Patient questionnaires for clinical research and improved standard patient care: is it better to have 80% of the information in 100% of patients or 100% of the information in 5% of patients?
    Theodore Pincus
    J Rheumatol 32:575-7. 2005
  81. ncbi request reprint Urgent care and tight control of rheumatoid arthritis as in diabetes and hypertension: better treatments but a shortage of rheumatologists
    Theodore Pincus
    Arthritis Rheum 46:851-4. 2002
  82. ncbi request reprint A composite disease activity scale for clinical practice, observational studies, and clinical trials: the patient activity scale (PAS/PAS-II)
    Frederick Wolfe
    National Data Bank for Rheumatic Diseases, University of Kansas School of Medicine, Wichita, Kansas 67214, USA
    J Rheumatol 32:2410-5. 2005
    ..To develop and validate a composite patient self-report disease activity scale for use in clinical practice and in observational studies and clinical trials...
  83. ncbi request reprint Continuous indices of core data set measures in rheumatoid arthritis clinical trials: lower responses to placebo than seen with categorical responses with the American College of Rheumatology 20% criteria
    Theodore Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 4500, USA
    Arthritis Rheum 52:1031-6. 2005
    ....
  84. ncbi request reprint Guidelines for monitoring of methotrexate therapy: "evidence-based medicine" outside of clinical trials
    Theodore Pincus
    Arthritis Rheum 48:2706-9. 2003
  85. ncbi request reprint Contemporary disease modifying antirheumatic drugs (DMARD) in patients with recent onset rheumatoid arthritis in a US private practice: methotrexate as the anchor drug in 90% and new DMARD in 30% of patients
    Tuulikki Sokka
    Vanderbilt University, Nashville, Tennessee 37232, USA
    J Rheumatol 29:2521-4. 2002
    ....
  86. ncbi request reprint Development and validation of the health assessment questionnaire II: a revised version of the health assessment questionnaire
    Frederick Wolfe
    Arthritis Research Center Foundation, Wichita, Kansas, USA
    Arthritis Rheum 50:3296-305. 2004
    ..We undertook this study to develop and validate a revised version of the HAQ (the HAQ-II)...
  87. ncbi request reprint Eligibility of patients in routine care for major clinical trials of anti-tumor necrosis factor alpha agents in rheumatoid arthritis
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Jyvaskyla, Finland
    Arthritis Rheum 48:313-8. 2003
    ....
  88. ncbi request reprint The assessment of rheumatoid arthritis and the acceptability of self-report questionnaires in clinical practice
    Frederick Wolfe
    National Data Bank for Rheumatic Diseases, University of Kansas School of Medicine, Wichita, Kansas, USA
    Arthritis Rheum 49:59-63. 2003
    ..To assess the acceptability of self-report questionnaires (SRQ) in clinical practice and to understand the value that rheumatologists give to various assessment methods in rheumatoid arthritis...
  89. ncbi request reprint Most patients receiving routine care for rheumatoid arthritis in 2001 did not meet inclusion criteria for most recent clinical trials or american college of rheumatology criteria for remission
    Tuulikki Sokka
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Rheumatol 30:1138-46. 2003
    ....
  90. ncbi request reprint Patients seen for standard rheumatoid arthritis care have significantly better articular, radiographic, laboratory, and functional status in 2000 than in 1985
    Theodore Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 4500, USA
    Arthritis Rheum 52:1009-19. 2005
    ..This study was undertaken to determine whether the clinical status of patients with rheumatoid arthritis (RA) has improved on average in recent years...
  91. ncbi request reprint Preliminary evaluation of a visual analog function scale for use in rheumatoid arthritis
    Frederick Wolfe
    Arthritis Research Center Foundation, University of Kansas School of Medicine, Wichita, KS 67214, USA
    J Rheumatol 32:1261-6. 2005
    ....
  92. ncbi request reprint Further development of a physical function scale on a MDHAQ [corrected] for standard care of patients with rheumatic diseases
    Theodore Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Rheumatol 32:1432-9. 2005
    ..3-0.5 units lower than HAQ scores...
  93. ncbi request reprint Why are only 50% of courses of anti-tumor necrosis factor agents continued for only 2 years in some settings? Need for longterm observations in standard care to complement clinical trials
    Theodore Pincus
    J Rheumatol 33:2372-5. 2006
  94. ncbi request reprint An index of patient reported outcomes (PRO-Index) discriminates effectively between active and control treatment in 4 clinical trials of adalimumab in rheumatoid arthritis
    Theodore Pincus
    Vanderbilt University Medical Center, 203 Oxford House, Nashville, TN 37232, USA
    J Rheumatol 33:2146-52. 2006
    ....
  95. ncbi request reprint Changes in Health Assessment Questionnaire disability scores over five years in patients with rheumatoid arthritis compared with the general population
    Tuulikki Sokka
    Jyvaskyla Central Hospital, Jyvaskyla, Finland
    Arthritis Rheum 54:3113-8. 2006
    ..To analyze longitudinal data over 5 years for changes in Health Assessment Questionnaire (HAQ) scores in patients with rheumatoid arthritis (RA) and age- and sex-matched controls from the general population...
  96. ncbi request reprint Shouldn't standard rheumatology clinical care be evidence-based rather than eminence-based, eloquence-based, or elegance-based?
    Theodore Pincus
    J Rheumatol 34:1-4. 2007
  97. ncbi request reprint N-of-1 trial of low-dose methotrexate and/or prednisolone in lieu of anti-CCP, MRI, or ultrasound, as first option in suspected rheumatoid arthritis?
    Theodore Pincus
    J Rheumatol 34:250-2. 2007
  98. ncbi request reprint Saving time and improving care with a multidimensional health assessment questionnaire: 10 practical considerations
    Theodore Pincus
    Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232 4500, USA
    J Rheumatol 33:448-54. 2006
  99. ncbi request reprint Quantitative measures to assess patients with rheumatic diseases: 2006 update
    Theodore Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Rheum Dis Clin North Am 32:29-36. 2006
  100. pmc QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries
    Tuulikki Sokka
    Arkisto Tutkijat, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
    Ann Rheum Dis 66:1491-6. 2007
    ..To conduct a cross-sectional review of non-selected consecutive outpatients with rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA...
  101. ncbi request reprint The disease activity score is not suitable as the sole criterion for initiation and evaluation of anti-tumor necrosis factor therapy in the clinic: discordance between assessment measures and limitations in questionnaire use for regulatory purposes
    Frederick Wolfe
    National Data Bank for Rheumatic Diseases, Wichita, Kansas 67214, USA
    Arthritis Rheum 52:3873-9. 2005
    ....