David Pickar

Summary

Publications

  1. ncbi request reprint Effect size of symptom status in withdrawal of typical antipsychotics and subsequent clozapine treatment in patients with treatment-resistant schizophrenia
    David Pickar
    Gabriel Pharma, Cabin John, MD 20818, USA
    Am J Psychiatry 160:1133-8. 2003
  2. ncbi request reprint Pharmacogenomics of psychiatric drug treatment
    David Pickar
    Gabriel Pharma, 6500 Seven Locks Road, Cabin John, MD 20818, USA
    Psychiatr Clin North Am 26:303-21, vii. 2003
  3. pmc Pharmacotherapy of schizophrenic patients: preponderance of off-label drug use
    David Pickar
    Gabriel Sciences, LLC, Cabin John, Maryland, USA
    PLoS ONE 3:e3150. 2008
  4. ncbi request reprint Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo
    Igor Elman
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuropsychopharmacology 27:293-300. 2002
  5. ncbi request reprint Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia
    Rob Nicolson
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Psychiatry 160:490-5. 2003
  6. ncbi request reprint Autonomic activity in relation to symptom ratings and reaction time in unmedicated patients with schizophrenia
    Theodore P Zahn
    Laboratory of Brain and Cognition, National Institutes of Health, Bldg 10 Rm 4C104, MSC 1366, Bethesda, MD 20892 1366, USA
    Schizophr Res 79:257-70. 2005

Research Grants

  1. Genetic Screen for Antipsychotic Drug Response
    David Pickar; Fiscal Year: 2005

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Effect size of symptom status in withdrawal of typical antipsychotics and subsequent clozapine treatment in patients with treatment-resistant schizophrenia
    David Pickar
    Gabriel Pharma, Cabin John, MD 20818, USA
    Am J Psychiatry 160:1133-8. 2003
    ..This study examines the effect size of symptom exacerbation during drug washout with placebo and the effects of drug washout on the efficacy of subsequent drug treatment...
  2. ncbi request reprint Pharmacogenomics of psychiatric drug treatment
    David Pickar
    Gabriel Pharma, 6500 Seven Locks Road, Cabin John, MD 20818, USA
    Psychiatr Clin North Am 26:303-21, vii. 2003
    ....
  3. pmc Pharmacotherapy of schizophrenic patients: preponderance of off-label drug use
    David Pickar
    Gabriel Sciences, LLC, Cabin John, Maryland, USA
    PLoS ONE 3:e3150. 2008
    ..These data are consistent with the recognition of the therapeutic limitations of both first and second generation antipsychotic drugs...
  4. ncbi request reprint Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo
    Igor Elman
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuropsychopharmacology 27:293-300. 2002
    ..Our data suggest that both risperidone and clozapine elevate plasma NE levels via enhanced neurotransmitter spillover, with risperidone producing a smaller effect...
  5. ncbi request reprint Parental schizophrenia spectrum disorders in childhood-onset and adult-onset schizophrenia
    Rob Nicolson
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Psychiatry 160:490-5. 2003
    ..In this study, the rates of schizophrenia spectrum disorders among parents of patients with childhood-onset and adult-onset schizophrenia and parents of community comparison subjects were compared...
  6. ncbi request reprint Autonomic activity in relation to symptom ratings and reaction time in unmedicated patients with schizophrenia
    Theodore P Zahn
    Laboratory of Brain and Cognition, National Institutes of Health, Bldg 10 Rm 4C104, MSC 1366, Bethesda, MD 20892 1366, USA
    Schizophr Res 79:257-70. 2005
    ..This paper explores further the role of autonomic activity in the pathogenesis of schizophrenia by relating differences in the autonomic variables among patients to symptom ratings and RT...

Research Grants1

  1. Genetic Screen for Antipsychotic Drug Response
    David Pickar; Fiscal Year: 2005
    ..This work has the potential of impacting the individual patient with schizophrenia as well as broader needs in related health care delivery. ..