Paolo Piaggi

Summary

Publications

  1. doi request reprint Adaptive filtering and random variables coefficient for analyzing functional magnetic resonance imaging data
    Paolo Piaggi
    Department of Energy and Systems Engineering, University of Pisa, Largo Lucio Lazzarino, Pisa, 56122, Italy
    Int J Neural Syst 23:1350011. 2013
  2. pmc Artificial neural networks in the outcome prediction of adjustable gastric banding in obese women
    Paolo Piaggi
    Department of Electrical Systems and Automation, University of Pisa, Pisa, Italy
    PLoS ONE 5:e13624. 2010
  3. pmc Lower energy expenditure predicts long-term increases in weight and fat mass
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    J Clin Endocrinol Metab 98:E703-7. 2013
  4. doi request reprint Patients with differentiated thyroid cancer who underwent radioiodine thyroid remnant ablation with low-activity ¹³¹I after either recombinant human TSH or thyroid hormone therapy withdrawal showed the same outcome after a 10-year follow-up
    Eleonora Molinaro
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, World Health Organization Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders, University of Pisa, 56100 Pisa, Italy
    J Clin Endocrinol Metab 98:2693-700. 2013
  5. pmc Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Hum Genet 133:1431-41. 2014
  6. pmc Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona
    Diabetes 62:4043-51. 2013
  7. pmc A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Phoenix, AZ, USA and
    Hum Mol Genet 24:2985-96. 2015
  8. pmc Overfeeding over 24 hours does not activate brown adipose tissue in humans
    Mathias Schlögl
    MD, Obesity and Diabetes Clinical Research Section, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, 4212 North 16th Street Fifth Floor, Phoenix, AZ 85016
    J Clin Endocrinol Metab 98:E1956-60. 2013
  9. doi request reprint Innovative approach to interpret the variability of biomarkers after ultra-endurance exercise: the multifactorial analysis
    Cristina Vassalle
    CNR Clinical Physiology Institute, Pisa, Italy
    Biomark Med 8:881-91. 2014
  10. pmc Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Diabetologia 57:1382-90. 2014

Collaborators

Detail Information

Publications29

  1. doi request reprint Adaptive filtering and random variables coefficient for analyzing functional magnetic resonance imaging data
    Paolo Piaggi
    Department of Energy and Systems Engineering, University of Pisa, Largo Lucio Lazzarino, Pisa, 56122, Italy
    Int J Neural Syst 23:1350011. 2013
    ..non-neural regions. As a result, adaptive filtering plus RV coefficient showed a greater suppression of PN and higher connectivity in neural regions, representing a novel effective approach to analyze fMRI data...
  2. pmc Artificial neural networks in the outcome prediction of adjustable gastric banding in obese women
    Paolo Piaggi
    Department of Electrical Systems and Automation, University of Pisa, Pisa, Italy
    PLoS ONE 5:e13624. 2010
    ....
  3. pmc Lower energy expenditure predicts long-term increases in weight and fat mass
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85016, USA
    J Clin Endocrinol Metab 98:E703-7. 2013
    ..The relevance of the contribution of energy expenditure (EE) and substrate oxidation to weight change has not been fully confirmed...
  4. doi request reprint Patients with differentiated thyroid cancer who underwent radioiodine thyroid remnant ablation with low-activity ¹³¹I after either recombinant human TSH or thyroid hormone therapy withdrawal showed the same outcome after a 10-year follow-up
    Eleonora Molinaro
    Unit of Endocrinology, Department of Clinical and Experimental Medicine, World Health Organization Collaborating Center for the Study and Treatment of Thyroid Diseases and Other Endocrine and Metabolic Disorders, University of Pisa, 56100 Pisa, Italy
    J Clin Endocrinol Metab 98:2693-700. 2013
    ..No long-term follow-up data are available for differentiated thyroid carcinoma (DTC) patients prepared with either exogenous or endogenous TSH and treated with low-activity (1.1 GBq [30 mCi]) radioiodine (¹³¹I)...
  5. pmc Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Hum Genet 133:1431-41. 2014
    ..2 %, p = 0.002), increased food intake (β = 676 kcal/day, p = 0.007) and decreased energy expenditure (β = -53.4 kcal/day, p = 0.054). Common and rare variation in MC4R contributes to obesity in American Indians...
  6. pmc Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona
    Diabetes 62:4043-51. 2013
    ..AFT may influence daily energy balance, is reduced in obese individuals, and predicts future weight gain in these subjects. Once central adiposity develops, a blunting of AFT may occur that then contributes to further weight gain...
  7. pmc A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Phoenix, AZ, USA and
    Hum Mol Genet 24:2985-96. 2015
    ..78, P = 0.03) and 30-min plasma insulin concentrations (β = 0.78, P = 1.1 × 10(-4)). Variation in PFKFB2 appears to reduce PFKFB2 expression in adipose and kidney tissues, and thereby increase risk for adiposity and DN. ..
  8. pmc Overfeeding over 24 hours does not activate brown adipose tissue in humans
    Mathias Schlögl
    MD, Obesity and Diabetes Clinical Research Section, National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, 4212 North 16th Street Fifth Floor, Phoenix, AZ 85016
    J Clin Endocrinol Metab 98:E1956-60. 2013
    ..Human brown adipose tissue (BAT) is activated with cold exposure, but it is unknown whether overfeeding activates BAT...
  9. doi request reprint Innovative approach to interpret the variability of biomarkers after ultra-endurance exercise: the multifactorial analysis
    Cristina Vassalle
    CNR Clinical Physiology Institute, Pisa, Italy
    Biomark Med 8:881-91. 2014
    ..MFA was used to estimate the associations among groups of parameters in order to identify concurrent changes in many different biochemical variables...
  10. pmc Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure
    Yunhua L Muller
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Diabetologia 57:1382-90. 2014
    ..Rare mutations in GCK cause MODY. We investigated whether common variation (minor allele frequency ≥0.01) in GCK is associated with metabolic traits and type 2 diabetes...
  11. doi request reprint Singular spectrum analysis and adaptive filtering enhance the functional connectivity analysis of resting state fMRI data
    Paolo Piaggi
    Department of Energy and Systems Engineering, University of Pisa, Largo Lucio Lazzarino, Pisa, 56122, Italy
    Int J Neural Syst 24:1450010. 2014
    ....
  12. doi request reprint Prevalence of left ventricular hypertrophy and determinants of left ventricular mass in obese women
    Guido Salvetti
    Obesity Centre at the Endocrinology Unit, University of Pisa, Pisa, Italy
    High Blood Press Cardiovasc Prev 19:33-9. 2012
    ..Obesity is frequently associated with left ventricular hypertrophy (LVH), a condition leading to an increased cardiovascular risk...
  13. doi request reprint Rehabilitative orbital decompression for Graves' orbitopathy: risk factors influencing the new onset of diplopia in primary gaze, outcome, and patients' satisfaction
    Roberto Rocchi
    Unit of Endocrinology, Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    Thyroid 22:1170-5. 2012
    ..Moreover, we investigated the results in terms of proptosis reduction, and the long-term subjective satisfaction of patients treated with OD with regard to their appearance and ocular function...
  14. doi request reprint Elevated level of serum carbohydrate antigen 19.9 as predictor of mortality in patients with advanced medullary thyroid cancer
    Rossella Elisei
    Endocrine UnitDepartment of Clinical and Experimental MedicineDepartment of SurgicalMedical, Molecular Pathology, University of Pisa, Pisa, Italy andClinical Chemistry LaboratoryAzienda Ospedaliero Universitaria Pisana, Pisa, Italy
    Eur J Endocrinol 173:297-304. 2015
    ..Recently, we observed an aggressive MTC with high levels of serum carbohydrate antigen 19.9 (Ca 19.9) and a rapid evolution to death...
  15. pmc Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP
    Anup K Nair
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 445 North 5th Street, Phoenix, AZ, 85004, USA
    Diabetologia 57:2334-8. 2014
    ..We assessed the replication of the seven lead single nucleotide polymorphisms (SNPs) and evaluated these loci for additional signals in American Indians...
  16. doi request reprint The different requirement of L-T4 therapy in congenital athyreosis compared with adult-acquired hypothyroidism suggests a persisting thyroid hormone resistance at the hypothalamic-pituitary level
    Brunella Bagattini
    Endocrinology SectionDepartment of Clinical and Experimental Medicine, University Hospital of Pisa, University of Pisa, Via Paradisa 2, Cisanello, Pisa 56124, Italy
    Eur J Endocrinol 171:615-21. 2014
    ..Levothyroxine (l-T4) is commonly employed to correct hormone deficiency in children with congenital hypothyroidism (CH) and in adult patients with iatrogenic hypothyroidism...
  17. pmc Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans
    Mathias Schlögl
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA Electronic address
    Appetite 90:154-9. 2015
    ..The relationship between food intake and irisin concentrations in humans is unclear...
  18. pmc Weight maintenance from young adult weight predicts better health outcomes
    Susanne B Votruba
    Obesity and Diabetes Clinical Research Section, NIDDK NIH DHHS, Phoenix, Arizona, USA
    Obesity (Silver Spring) 22:2361-9. 2014
    ..Defining groups of individuals within a larger population with similar patterns of weight change over time may provide insight into influences of weight stability or gain...
  19. doi request reprint The BRAF(V600E) mutation is an independent, poor prognostic factor for the outcome of patients with low-risk intrathyroid papillary thyroid carcinoma: single-institution results from a large cohort study
    Rossella Elisei
    Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy
    J Clin Endocrinol Metab 97:4390-8. 2012
    ..The aim of this study was to evaluate its prognostic significance in a large cohort of low-risk intrathyroid PTC...
  20. doi request reprint Serum insulin-like growth factor-1 concentrations are reduced in severely obese women and raise after weight loss induced by laparoscopic adjustable gastric banding
    Giulia Galli
    Endocrinology Unit, University Hospital of Pisa, Pisa, Italy
    Obes Surg 22:1276-80. 2012
    ..Obesity is associated with abnormalities of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis. The role of serum IGF-1 measurement for recognition of hypothalamic-pituitary diseases in obesity is still a matter of debate...
  21. pmc Abnormal T2-STIR Magnetic Resonance in Hypertrophic Cardiomyopathy: A Marker of Advanced Disease and Electrical Myocardial Instability
    Giancarlo Todiere
    Fondazione G Monasterio Regione Toscana National Research Council, Pisa, Italy
    PLoS ONE 9:e111366. 2014
    ..The aim of the current study was to evaluate the relationship between HyT2 and both a) markers of ventricular electrical instability and b) clinical and CMR parameters...
  22. pmc Fasting hyperglycemia predicts lower rates of weight gain by increased energy expenditure and fat oxidation rate
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section P P, M S T, C B, J K, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016 and Obesity Research Center, Endocrinology Unit P P, University Hospital of Pisa, Pisa, Italy, 56124
    J Clin Endocrinol Metab 100:1078-87. 2015
    ..One possible mechanism is via increased energy expenditure (EE)...
  23. doi request reprint The large majority of 1520 patients with indeterminate thyroid nodule at cytology have a favorable outcome, and a clinical risk score has a high negative predictive value for a more cumbersome cancer disease
    Teresa Rago
    Endocrinology Unit T R, M S, V L, M T, P V, University Hospital Department of Electric Systems and Automation P P Department of Oncology Section of Cytopathology Pathology 1 I M, R R and 3 F B and Department of Surgery P M, University of Pisa, 56124 Pisa, Italy
    J Clin Endocrinol Metab 99:3700-7. 2014
    ..Clinical management of patients with thyroid nodules indeterminate at fine-needle aspiration (FNA) cytology is still unsettled...
  24. pmc Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating
    Paolo Piaggi
    Obesity and Diabetes Clinical Research Section P P, M S T, J K, S B V, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016 and Obesity Research Center P P, Endocrinology Unit, University Hospital of Pisa, Pisa, Italy 56124
    J Clin Endocrinol Metab 100:3011-20. 2015
    ..Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake...
  25. pmc Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes
    Ke Huang
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona, USA
    Obesity (Silver Spring) 22:984-8. 2014
    ..The objective of this study was to identify coding variation that increases risk for T2D via an effect on a pre-diabetic trait...
  26. doi request reprint Progression of myocardial fibrosis assessed with cardiac magnetic resonance in hypertrophic cardiomyopathy
    Giancarlo Todiere
    Fondazione G Monasterio CNR Regione Toscana, Pisa, Italy
    J Am Coll Cardiol 60:922-9. 2012
    ..This study sought to assess the rate of progression of fibrosis by 2 consecutive cardiac magnetic resonance (CMR) examinations and its relation with clinical variables...
  27. doi request reprint Early subclinical increase in pulmonary water content in athletes performing sustained heavy exercise at sea level: ultrasound lung comet-tail evidence
    Alessandro Pingitore
    CNR Institute of Clinical Physiology, Scuola Superiore Sant Anna, Pisa, Italy
    Am J Physiol Heart Circ Physiol 301:H2161-7. 2011
    ..Hemodynamic changes are one of several potential factors contributing to the mechanisms of ULCs...
  28. doi request reprint Iodine fortification of vegetables improves human iodine nutrition: in vivo evidence for a new model of iodine prophylaxis
    Massimo Tonacchera
    Department of Clinical and Experimental Medicine, Section of Endocrinology, Research Center of Excellence AmbiSEN, University of Pisa, 56124 Pisa, Italy
    J Clin Endocrinol Metab 98:E694-7. 2013
    ..In most industrialized countries, excess consumption of salt has become recognized as a health risk. Therefore, biofortification of vegetables with iodine offers an excellent opportunity to increase iodine intake...
  29. doi request reprint Lymphocytic thyroiditis on histology correlates with serum thyroglobulin autoantibodies in patients with papillary thyroid carcinoma: impact on detection of serum thyroglobulin
    Francesco Latrofa
    Department of Endocrinology, University Hospital of Pisa, Via Cisanello 2, 56124, Pisa, Italy
    J Clin Endocrinol Metab 97:2380-7. 2012
    ..TgAb are due to a coexistent lymphocytic thyroiditis (LT) or the papillary thyroid carcinoma per se. TgAb assays are highly discordant...