William D Phillips

Summary

Publications

  1. doi request reprint Effects of the ß2-Adrenoceptor Agonist, Albuterol, in a Mouse Model of Anti-MuSK Myasthenia Gravis
    Nazanin Ghazanfari
    Physiology and Bosch Institute, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 9:e87840. 2014
  2. pmc Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody
    Marco Morsch
    School of Medical Sciences Physiology and Bosch Institute, Anderson Stuart Bldg F13, University of Sydney, NSW 2006, Australia
    J Physiol 591:2747-62. 2013
  3. doi request reprint Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors
    Marco Morsch
    School of Medical Sciences Physiology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia
    Exp Neurol 237:286-95. 2012
  4. doi request reprint Muscle specific kinase: organiser of synaptic membrane domains
    Nazanin Ghazanfari
    Physiology and Bosch Institute, Anderson Stuart Bldg F13, The University of Sydney, Sydney, NSW 2006, Australia
    Int J Biochem Cell Biol 43:295-8. 2011

Collaborators

Detail Information

Publications4

  1. doi request reprint Effects of the ß2-Adrenoceptor Agonist, Albuterol, in a Mouse Model of Anti-MuSK Myasthenia Gravis
    Nazanin Ghazanfari
    Physiology and Bosch Institute, University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 9:e87840. 2014
    ..The results also demonstrate that it is possible for albuterol treatment to reduce whole-body weakness without necessarily reversing myasthenic impairment to the structure and function of the neuromuscular junction. ..
  2. pmc Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody
    Marco Morsch
    School of Medical Sciences Physiology and Bosch Institute, Anderson Stuart Bldg F13, University of Sydney, NSW 2006, Australia
    J Physiol 591:2747-62. 2013
    ..These results thus suggest that ongoing pyridostigmine treatment potentiates anti-MuSK-induced AChR loss by prolonging the activity of ACh in the synaptic cleft...
  3. doi request reprint Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors
    Marco Morsch
    School of Medical Sciences Physiology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006, Australia
    Exp Neurol 237:286-95. 2012
    ..Consequent reductions in endplate potential amplitudes culminated in failure of neuromuscular transmission...
  4. doi request reprint Muscle specific kinase: organiser of synaptic membrane domains
    Nazanin Ghazanfari
    Physiology and Bosch Institute, Anderson Stuart Bldg F13, The University of Sydney, Sydney, NSW 2006, Australia
    Int J Biochem Cell Biol 43:295-8. 2011
    ..The importance of MuSK as a synapse organiser is highlighted by cases of autoimmune myasthenia gravis in which MuSK autoantibodies can deplete MuSK from the postsynaptic membrane, leading to complete disassembly of the adult NMJ...