An in vivo comparison of the potential for extravertebral cement leak after vertebroplasty and kyphoplastyFrank M Phillips
University of Chicago Spine Center, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 27:2173-8; discussion 2178-9. 2002
..A prospective in vivo study was conducted during the performance of kyphoplasty for the treatment of osteoporotic vertebral compression fractures, comparing extravertebral contrast extravasation with kyphoplasty and vertebroplasty...
- Managing chronic pain of spinal origin after lumbar surgery: the role of decompressive surgery
Frank M Phillips
University of Chicago Spine Center, Section of Orthopaedic Surgery, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 27:2547-53; discussion 2554. 2002
..A literature review was conducted...
- Minimally invasive treatments of osteoporotic vertebral compression fractures
Frank M Phillips
University of Chicago Spine Center, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 28:S45-53. 2003
..A literature review of experiences with vertebroplasty and kyphoplasty for treating symptomatic, osteoporotic vertebral compression fractures (VCFs)...
- A prospective, randomized, double-blind study evaluating the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after spinal arthrodesis
Kern Singh
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 30:2477-83. 2005
..Parallel design, prospective, double-blind, randomized, controlled trial composed of two independent groups treated with a continuous infusion catheter (saline vs. Marcaine) placed into the iliac crest bone graft (ICBG) site...
- Biomechanics of posterior dynamic stabilizing device (DIAM) after facetectomy and discectomy
Frank M Phillips
Rush University Medical Center, 1725 W. Harrison Street, Chicago, IL 60612, USA
Spine J 6:714-22. 2006
..05). Interestingly, the DIAM device did not reduce the increased axial rotation motion observed after discectomy. These biomechanical effects must be considered when evaluating the clinical applications of the DIAM...
Effect of the Total Facet Arthroplasty System after complete laminectomy-facetectomy on the biomechanics of implanted and adjacent segmentsFrank M Phillips
Rush University Medical Center, Chicago, IL, USA
Spine J 9:96-102. 2009
..The Total Facet Arthroplasty System (TFAS) is a motion-restoring implant suggested as an alternative to rigid fixation after complete facetectomy...
- Index and adjacent level kinematics after cervical disc replacement and anterior fusion: in vivo quantitative radiographic analysis
Daniel K Park
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA
Spine (Phila Pa 1976) 36:721-30. 2011
..Prospective, randomized trial...
- Minimally invasive techniques for the treatment of osteoporotic vertebral fractures
Neil A Manson
Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, Illinois, USA
Instr Course Lect 56:273-85. 2007
..Recently, vertebral augmentation during spinal decompression and instrumented fusion for burst fracture with neurologic insult has been reported to be successful...
- A comparison of perioperative costs and outcomes in patients with and without workers' compensation claims treated with minimally invasive or open transforaminal lumbar interbody fusion
Miguel A Pelton
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 37:1914-9. 2012
..A nonrandomized, nonblinded prospective review...
- Factors affecting reoperations after anterior cervical discectomy and fusion within and outside of a Federal Drug Administration investigational device exemption cervical disc replacement trial
Kern Singh
Department of Orthopedic Surgery, Rush University Medical Center, 1611 West Harrison St, Chicago, IL 60612, USA
Spine J 12:372-8. 2012
..8% (5/276), 5.8% (14/242), 1.9% (2/103), 11% (15/136), and 1.2% (2/164) (mean = 4.34%) in patients receiving the cervical TDR. The rate of reoperation within 2 years after ACDF seems unusually high...
- Congenital lumbar spinal stenosis: a prospective, control-matched, cohort radiographic analysis
Kern Singh
Department of Orthopedic Surgery, Rush University Medical Center, 1725 West Harrison Street, Chicago, IL 60612, USA
Spine J 5:615-22. 2005
..Identification of the presence of congenital stenosis should increase the treating surgeon's awareness of the potential need for multilevel treatment...
- Repeat use of human recombinant bone morphogenetic protein-2 for second level lumbar arthrodesis
Kern Singh
Department of Orthopedic Surgery, Rush University, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 36:192-6. 2011
..Prospective randomized controlled animal model...
- Transduced bovine articular chondrocytes affect the metabolism of cocultured nucleus pulposus cells in vitro: implications for chondrocyte transplantation into the intervertebral disc
Yejia Zhang
Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA
Spine 30:2601-7. 2005
..If applied to the treatment of disc degeneration, this strategy could provide the disc with not only metabolically active chondrocytes but also promote matrix replenishment by stimulating native NP cells...
- Early radiographic and clinical results of balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures
Frank M Phillips
The University of Chicago Spine Center, Chicago, Illinois, USA
Spine (Phila Pa 1976) 28:2260-5; discussion 2265-7. 2003
..A prospective consecutive cohort study of clinical and radiographic outcomes after kyphoplasty for treatment of osteoporotic vertebral compression fractures...
- Cervical disc replacement in patients with and without previous adjacent level fusion surgery: a prospective study
Frank M Phillips
Rush University Medical Center, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 34:556-65. 2009
..Prospective 6-center study. OBJECTIVE.: To evaluate outcomes of cervical disc replacement performed adjacent to a prior cervical fusion...
- Open vertebral cement augmentation combined with lumbar decompression for the operative management of thoracolumbar stenosis secondary to osteoporotic burst fractures
Kern Singh
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA
J Spinal Disord Tech 18:413-9. 2005
..Although clinically successful, this technique warrants careful patient selection...
- In vivo BMP-7 (OP-1) enhancement of osteoporotic vertebral bodies in an ovine model
Frank M Phillips
Rush University Medical Center, 1725 W Harrison Street, Suite 1063, Chicago, IL 60612, USA
Spine J 6:500-6. 2006
..The mechanism of action of the bone morphogenetic protein (BMP) family theoretically makes these molecules candidates for rapidly enhancing local bone structure...
- Gene therapy for spinal fusion
Frank M Phillips
Rush University Medical Center, 1725 West Harrison Street, Suite 1063, Chicago, IL 60612, USA
Spine J 5:250S-258S. 2005
..Considerable research is required to identify gene therapy techniques and vectors with acceptable safety profiles and high fusion rates...
- Minimally invasive techniques for the treatment of osteoporotic vertebral fractures
Neil A Manson
Rush University Medical Center, 1725 West Harrison Street, Suite 1063, Chicago, IL 60612, USA
J Bone Joint Surg Am 88:1862-72. 2006
- Cervical disc replacement
Frank M Phillips
Rush University Medical Center, Chicago, IL 60062, USA
Spine (Phila Pa 1976) 30:S27-33. 2005
..Review article...
- Minimally invasive spine surgery
J Alex Seldomridge
Department of Orthopaedic Surgery, Rush University, Chicago, Illinois, USA
Am J Orthop 34:224-32; discussion 232. 2005
..Here we summarize the rationale for the trend toward spinal MIS and highlight the more common procedures...
- Radiographic criteria for placement of translaminar facet screws
Frank M Phillips
Rush Presbyterian St Luke s Medical Center, 1725 West Harrison Street, Suite 1063, Chicago, IL 60612, USA
Spine J 4:465-7. 2004
..Accurate placement of translaminar facet screws (TLFSs) requires identification of the posterior spinal elements, and the facet joints in particular, which may be facilitated by intra-operative fluoroscopy...
- The relationship of intrapsoas nerves during a transpsoas approach to the lumbar spine: anatomic study
Daniel K Park
Rush University Medical Center, Chicago, IL 60612, USA
J Spinal Disord Tech 23:223-8. 2010
..A cadaveric study...
- A prospective, randomized, double-blind study of the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after posterior spinal arthrodesis: a minimum of 4-year follow-up
Kern Singh
Rush University Medical Center, Department of Orthopaedic Surgery, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 32:2790-6. 2007
..Parallel design, prospective, double-blinded, randomized, controlled trial composed of 2 independent groups treated with a continuous infusion catheter (saline vs. Marcain) placed into the iliac crest bone graft site (ICBG)...
- Minimally invasive treatments of osteoporotic vertebral compression fractures: vertebroplasty and kyphoplasty
Frank M Phillips
University of Chicago Spine Center, Chicago, Illinois, USA
Instr Course Lect 52:559-67. 2003
..Kyphoplasty allows for low-pressure cement injection and affords the opportunity to correct spinal deformity. Further study is required to define the precise indications, timing, and relative merits of these techniques...
The action of resveratrol, a phytoestrogen found in grapes, on the intervertebral discXin Li
Department of Biochemistry, Section of Rheumatology, Rush University Medical Center, Chicago, IL 60612, USA
Spine (Phila Pa 1976) 33:2586-95. 2008
..Basic science, biologic study...
- Effect of supplemental translaminar facet screw fixation on the stability of stand-alone anterior lumbar interbody fusion cages under physiologic compressive preloads
Frank M Phillips
Department of Orthopaedic Surgery, Rush Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA
Spine 29:1731-6. 2004
....
- Intradiscal electrothermal therapy used to manage chronic discogenic low back pain: new directions and interventions
F Todd Wetzel
Section of Orthopaedic Surgery and Rehabilitation and Anesthesia and Critical Care, University of Chicago Spine Center, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 27:2621-6. 2002
..Retrospective literature review...
- Intertransverse lumbar interbody fusion
Frank M Phillips
University of Chicago Spine Center, Section of Orthopaedic Surgery, Chicago, Illinois 60640, USA
Spine (Phila Pa 1976) 27:E37-41. 2002
..Cadaver dissection and case reports were used to describe a novel technique of lumbar interbody arthrodesis that accesses the intervertebral disc through a posterolateral intertransverse process approach...
- Potential use of Sox9 gene therapy for intervertebral degenerative disc disease
Ronjon Paul
Molecular Oncology Laboratory and the Spine Center, Department of Surgery, University of Chicago Medical Center, Chicago, Illinois 60640, USA
Spine 28:755-63. 2003
..In a rabbit model, sustained Sox9 production preserved the histologic appearance of the nucleus pulposus cells in vivo. These findings suggest a potential role for Sox9 gene therapy in the treatment of human degenerative disc disease...
- The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Alexander R Vaccaro
Department of Orthopaedic Surgery, Thomas Jefferson University and the Rothman Institute, 925 Chestnut Street, 5 th Floor, Philadelphia, Pennsylvania, PA 19107, USA
Spine J 8:457-65. 2008
..Previous clinical studies involving patients with degenerative spondylolisthesis have reported that the efficacy and safety of OP-1 Putty is comparable to that of autograft at both 1- and 2-year follow-up...
- Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: a reappraisal of the vertebral venous system
Rob J M Groen
Department of Neurosurgery, University Hospital Groningen, Grongingen, The Netherlands
Spine (Phila Pa 1976) 29:1465-71. 2004
....
- Vertebral augmentation and the limits of interpreting complications reported in the food and drug administration manufacturer and user facility device experience database
Isador H Lieberman
Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
J Vasc Interv Radiol 15:1193-6. 2004
- Static versus dynamic plating for multilevel anterior cervical discectomy and fusion
Christian M DuBois
St Croix Orthopaedics, 1991 Northwestern Avenue, South Stillwater, MN 55105, USA
Spine J 7:188-93. 2007
..To date these proposed benefits have been largely theoretical and there are no studies confirming any benefits over more traditional static plates...
- Editorial: are spine biologics the future in spinal surgery?
Howard S An
Spine J 5:207S-208S. 2005
- Restoring geometric and loading alignment of the thoracic spine with a vertebral compression fracture: effects of balloon (bone tamp) inflation and spinal extension
Ioannis N Gaitanis
Department of Veterans Affairs, Edward Hines Jr. Veterans Affairs Hospital, 5th Avenue and Roosevelt Road, P.O. Box 5000 (151, Hines, IL 60141, USA
Spine J 5:45-54. 2005
....
- Interbody cage devices
Thomas A Zdeblick
Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconsin, USA
Spine 28:S2-7. 2003
..CONCLUSION: Interbody cages are a useful technique for achieving spinal fusion and have been shown to have an acceptable clinical success rate in appropriately selected patients...
- Minimally invasive fusion: summary statement
Richard D Guyer
Spine 28:S44. 2003
..In other words, minimal invasion should not equate to minimally effective...
- Biologic treatment for intervertebral disc degeneration: summary statement
Frank M Phillips
Spine 28:S99. 2003
..Preliminary studies using these strategies have confirmed their ability to replenish essential disc matrix components that are known to decrease with disc degeneration...
- Compressive preload improves the stability of anterior lumbar interbody fusion cage constructs
Avinash G Patwardhan
Musculoskeletal Biomechanics Laboratory, Department of Veterans Affairs, Edward J Hines Veterans Affairs Hospital, Hines, Illinois 60141, USA
J Bone Joint Surg Am 85:1749-56. 2003
..This study tested the hypothesis that the ability of the cages to reduce the segmental motions in flexion and extension is significantly affected by the magnitude of the externally applied compressive preload...
- The use of bone morphogenetic protein in lumbar spine surgery
Jeffrey A Rihn
Department of Orthopaedic Surgery, The Rothman Institute, Thomas Jefferson University Hospital, 925 Chestnut Street, 5th Floor, Philadelphia, PA 19107, USA
J Bone Joint Surg Am 90:2014-25. 2008
- The argument for noninstrumented posterolateral fusion for patients with spinal stenosis and degenerative spondylolisthesis
Frank M Phillips
Spine 29:170-2. 2004
- Osteoporotic spinal deformity: a biomechanical rationale for the clinical consequences and treatment of vertebral body compression fractures
Hansen A Yuan
Department of Orthopaedic and Neurologic Surgery, State University of New York Syracuse Medical Center, Syracuse, NY 13202, USA
J Spinal Disord Tech 17:236-42. 2004
..Balloon kyphoplasty, the minimally invasive technique of reduction and internal fixation of osteopenic vertebral body compression fractures that addresses pain and spinal deformity, is discussed...
- L5-S1 laparoscopic anterior interbody fusion
Constantine T Frantzides
Minimally Invasive Surgery Center, Department of Surgery, Evanston Northwestern Healthcare and Northwestern University, Evanston, Illinois 60201, USA
JSLS 10:488-92. 2006
..We evaluated our experience with laparoscopic L5-S1 anterior lumbar interbody fusion (ALIF)...
- Summary statement: biologics for spine fusion
Jonathan N Grauer
Spine J 5:259S. 2005
- The future of spinal fusion
Howard An
Orthopedics 29:683-4. 2006
