R L Rosales

Summary

Affiliation: University of Santo Tomas
Country: Philippines

Publications

  1. ncbi Pharmacology of botulinum toxin: differences between type A preparations
    R L Rosales
    Department of Neurology and Psychiatry Research Center for Health Sciences, University of Santo Tomas and The Center for Movement Disorders, St Lukes Medical Center, Manila, Philippines
    Eur J Neurol 13:2-10. 2006
  2. doi Evidence-based systematic review on the efficacy and safety of botulinum toxin-A therapy in post-stroke spasticity
    R L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Manila, Philippines
    J Neural Transm 115:617-23. 2008
  3. doi On muscle spindles, dystonia and botulinum toxin
    R L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Sampaloc, Metro Manila, Philippines
    Eur J Neurol 17:71-80. 2010
  4. doi The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part I): muscle afferent block versus botulinum toxin-A in cervical and limb dystonias
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
    Int J Neurosci 121:35-43. 2011
  5. doi The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part II): an open-label experience with botulinum toxin-A (Dysport®) injections for oromandibular, lingual, and truncal-axial dystonias
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
    Int J Neurosci 121:44-56. 2011
  6. doi Cilostazol: a pilot study on safety and clinical efficacy in neuropathies of diabetes mellitus type 2 (ASCEND)
    Raymond L Rosales
    Department of Neurology and Psychiatry, Faculty of Medicine and Surgery, The University of Santo Tomas Hospital, Manila, Philippines
    Angiology 62:625-35. 2011
  7. doi What's the "catch" in upper-limb post-stroke spasticity: expanding the role of botulinum toxin applications
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Manila 1008, Philippines
    Parkinsonism Relat Disord 17:S3-10. 2011

Detail Information

Publications7

  1. ncbi Pharmacology of botulinum toxin: differences between type A preparations
    R L Rosales
    Department of Neurology and Psychiatry Research Center for Health Sciences, University of Santo Tomas and The Center for Movement Disorders, St Lukes Medical Center, Manila, Philippines
    Eur J Neurol 13:2-10. 2006
    ..Atrophy of extrafusal muscle fibers of injected and remote muscles do not differ between the BoNTA preparations...
  2. doi Evidence-based systematic review on the efficacy and safety of botulinum toxin-A therapy in post-stroke spasticity
    R L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Manila, Philippines
    J Neural Transm 115:617-23. 2008
    ..In this article, we summarized the data of randomized, placebo-controlled, double- blind trials and conducted a meta-analysis to assess if BoNTA is an adequate treatment for spasticity following stroke...
  3. doi On muscle spindles, dystonia and botulinum toxin
    R L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Sampaloc, Metro Manila, Philippines
    Eur J Neurol 17:71-80. 2010
    ..Thus, in dystonia, overactivity of muscles and increased spindle sensitivity are germane to botulinum toxin targets of action...
  4. doi The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part I): muscle afferent block versus botulinum toxin-A in cervical and limb dystonias
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
    Int J Neurosci 121:35-43. 2011
    ..However, because MAB is a more cost-effective alternative that can be given repeatedly, it has been used in the XDP population while awaiting funds for BoNT type-A and/or for selecting muscles for injection as a test drug...
  5. doi The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part II): an open-label experience with botulinum toxin-A (Dysport®) injections for oromandibular, lingual, and truncal-axial dystonias
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
    Int J Neurosci 121:44-56. 2011
    ..Thus, BoNT-A injection working protocols may be adopted in XDP dystonia that adheres to cost minimization (e.g., lower dose end per selected muscle), while achieving some benefit, and potentially reduce the adverse event profile...
  6. doi Cilostazol: a pilot study on safety and clinical efficacy in neuropathies of diabetes mellitus type 2 (ASCEND)
    Raymond L Rosales
    Department of Neurology and Psychiatry, Faculty of Medicine and Surgery, The University of Santo Tomas Hospital, Manila, Philippines
    Angiology 62:625-35. 2011
    ..Diabetic polyneuropathy may have vascular and metabolic components in its pathophysiologic mechanism. Cilostazol, aside from its antiplatelet and vasodilatory properties, may increase nerve blood flow and potentially improve neuropathy...
  7. doi What's the "catch" in upper-limb post-stroke spasticity: expanding the role of botulinum toxin applications
    Raymond L Rosales
    Department of Neurology and Psychiatry, University of Santo Tomas, Manila 1008, Philippines
    Parkinsonism Relat Disord 17:S3-10. 2011
    ....