Research Topics
| R L RosalesSummaryAffiliation: University of Santo Tomas Country: Philippines Publications
| Collaborators |
Detail Information
Publications
Pharmacology of botulinum toxin: differences between type A preparationsR L Rosales
Department of Neurology and Psychiatry Research Center for Health Sciences, University of Santo Tomas and The Center for Movement Disorders, St Lukes Medical Center, Manila, Philippines
Eur J Neurol 13:2-10. 2006..Atrophy of extrafusal muscle fibers of injected and remote muscles do not differ between the BoNTA preparations...
Evidence-based systematic review on the efficacy and safety of botulinum toxin-A therapy in post-stroke spasticityR L Rosales
Department of Neurology and Psychiatry, University of Santo Tomas, Manila, Philippines
J Neural Transm 115:617-23. 2008..In this article, we summarized the data of randomized, placebo-controlled, double- blind trials and conducted a meta-analysis to assess if BoNTA is an adequate treatment for spasticity following stroke...
On muscle spindles, dystonia and botulinum toxinR L Rosales
Department of Neurology and Psychiatry, University of Santo Tomas, Sampaloc, Metro Manila, Philippines
Eur J Neurol 17:71-80. 2010..Thus, in dystonia, overactivity of muscles and increased spindle sensitivity are germane to botulinum toxin targets of action...
The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part I): muscle afferent block versus botulinum toxin-A in cervical and limb dystoniasRaymond L Rosales
Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
Int J Neurosci 121:35-43. 2011..However, because MAB is a more cost-effective alternative that can be given repeatedly, it has been used in the XDP population while awaiting funds for BoNT type-A and/or for selecting muscles for injection as a test drug...
The broadening application of chemodenervation in X-linked dystonia-parkinsonism (Part II): an open-label experience with botulinum toxin-A (Dysport®) injections for oromandibular, lingual, and truncal-axial dystoniasRaymond L Rosales
Department of Neurology and Psychiatry, University of Santo Tomas Hospital, Manila, Philippines
Int J Neurosci 121:44-56. 2011..Thus, BoNT-A injection working protocols may be adopted in XDP dystonia that adheres to cost minimization (e.g., lower dose end per selected muscle), while achieving some benefit, and potentially reduce the adverse event profile...
Cilostazol: a pilot study on safety and clinical efficacy in neuropathies of diabetes mellitus type 2 (ASCEND)Raymond L Rosales
Department of Neurology and Psychiatry, Faculty of Medicine and Surgery, The University of Santo Tomas Hospital, Manila, Philippines
Angiology 62:625-35. 2011..Diabetic polyneuropathy may have vascular and metabolic components in its pathophysiologic mechanism. Cilostazol, aside from its antiplatelet and vasodilatory properties, may increase nerve blood flow and potentially improve neuropathy...
What's the "catch" in upper-limb post-stroke spasticity: expanding the role of botulinum toxin applicationsRaymond L Rosales
Department of Neurology and Psychiatry, University of Santo Tomas, Manila 1008, Philippines
Parkinsonism Relat Disord 17:S3-10. 2011....
