A Pezzini

Summary

Publications

  1. Giossi A, Mardighian D, Caria F, Poli L, De Giuli V, Costa P, et al. Arterial tortuosity in patients with spontaneous cervical artery dissection. Neuroradiology. 2017;59:571-575 pubmed publisher
    ..This might have potential implications for better understanding of the pathophysiology of the disease as well as clinical utility in evaluation, prognostication, and decision-making of affected individuals. ..
  2. request reprint
    Pezzini A, Del Zotto E, Archetti S, Negrini R, Bani P, Albertini A, et al. Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke. 2002;33:664-9 pubmed
    ..Our results are consistent with the hypothesis that increased plasma homocysteine levels and the TT MTHFR genotype may represent risk factors for sCAD. In contrast, their role in atherothrombotic strokes remains a contentious issue. ..
  3. request reprint
    Pezzini A, Grassi M, Del Zotto E, Bazzoli E, Archetti S, Assanelli D, et al. Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults. Stroke. 2004;35:438-42 pubmed
    ..This finding may help in determining an individual's predisposition to stroke and more targeted preventive interventions. ..
  4. request reprint
    Pezzini A, Grassi M, Del Zotto E, Archetti S, Spezi R, Vergani V, et al. Cumulative effect of predisposing genotypes and their interaction with modifiable factors on the risk of ischemic stroke in young adults. Stroke. 2005;36:533-9 pubmed
    ..These data suggest a gene-dose effect of the examined prothrombotic and proatherogenic gene variants and a synergistic effect of these polymorphisms and modifiable risk factors in the pathogenesis of cerebral ischemia in young adults. ..
  5. request reprint
    Pezzini A, Grassi M, Del Zotto E, Giossi A, Monastero R, Dalla Volta G, et al. Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect. Stroke. 2007;38:3145-51 pubmed
    ..22 for TT genotype) as compared with controls. Migraine may act as mediator in the methylenetetrahydrofolate reductase-ischemic stroke pathway with a more prominent effect in the subgroup of patients with spontaneous artery dissection. ..
  6. request reprint
    Pezzini A, Grassi M, Zotto E, Giossi A, Volonghi I, Costa P, et al. Do common prothrombotic mutations influence the risk of cerebral ischaemia in patients with patent foramen ovale? Systematic review and meta-analysis. Thromb Haemost. 2009;101:813-7 pubmed
    ..Addition of common prothrombotic genetic variants to standard initial screening may contribute to stratifying PFO-associated stroke patients at different risk of ischaemic events and targeting secondary prevention strategies. ..
  7. request reprint
    Pezzini A, Del Zotto E, Volonghi I, Giossi A, Costa P, Padovani A. Cerebral amyloid angiopathy: a common cause of cerebral hemorrhage. Curr Med Chem. 2009;16:2498-513 pubmed
    ..The present paper summarizes epidemiologic and clinical aspects of CAA, and highlights the presumed pathomechanisms of amyloid deposition in both sporadic and hereditary forms. ..
  8. Pezzini A, Grassi M, Del Zotto E, Lodigiani C, Ferrazzi P, Spalloni A, et al. Common genetic markers and prediction of recurrent events after ischemic stroke in young adults. Neurology. 2009;73:717-23 pubmed publisher
    ..The NRI was also significant (NRI = 0.172, test z = 2.17). Addition of common genetic variants to traditional risk factors may be an effective method for discriminating young stroke patients at different risk of future ischemic events. ..
  9. Pezzini A, Drera B, Del Zotto E, Ritelli M, Carletti M, Tomelleri G, et al. Mutations in TGFBR2 gene cause spontaneous cervical artery dissection. J Neurol Neurosurg Psychiatry. 2011;82:1372-4 pubmed publisher
    ....

Locale

Collaborators

Detail Information

Publications9

  1. Giossi A, Mardighian D, Caria F, Poli L, De Giuli V, Costa P, et al. Arterial tortuosity in patients with spontaneous cervical artery dissection. Neuroradiology. 2017;59:571-575 pubmed publisher
    ..This might have potential implications for better understanding of the pathophysiology of the disease as well as clinical utility in evaluation, prognostication, and decision-making of affected individuals. ..
  2. request reprint
    Pezzini A, Del Zotto E, Archetti S, Negrini R, Bani P, Albertini A, et al. Plasma homocysteine concentration, C677T MTHFR genotype, and 844ins68bp CBS genotype in young adults with spontaneous cervical artery dissection and atherothrombotic stroke. Stroke. 2002;33:664-9 pubmed
    ..Our results are consistent with the hypothesis that increased plasma homocysteine levels and the TT MTHFR genotype may represent risk factors for sCAD. In contrast, their role in atherothrombotic strokes remains a contentious issue. ..
  3. request reprint
    Pezzini A, Grassi M, Del Zotto E, Bazzoli E, Archetti S, Assanelli D, et al. Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults. Stroke. 2004;35:438-42 pubmed
    ..This finding may help in determining an individual's predisposition to stroke and more targeted preventive interventions. ..
  4. request reprint
    Pezzini A, Grassi M, Del Zotto E, Archetti S, Spezi R, Vergani V, et al. Cumulative effect of predisposing genotypes and their interaction with modifiable factors on the risk of ischemic stroke in young adults. Stroke. 2005;36:533-9 pubmed
    ..These data suggest a gene-dose effect of the examined prothrombotic and proatherogenic gene variants and a synergistic effect of these polymorphisms and modifiable risk factors in the pathogenesis of cerebral ischemia in young adults. ..
  5. request reprint
    Pezzini A, Grassi M, Del Zotto E, Giossi A, Monastero R, Dalla Volta G, et al. Migraine mediates the influence of C677T MTHFR genotypes on ischemic stroke risk with a stroke-subtype effect. Stroke. 2007;38:3145-51 pubmed
    ..22 for TT genotype) as compared with controls. Migraine may act as mediator in the methylenetetrahydrofolate reductase-ischemic stroke pathway with a more prominent effect in the subgroup of patients with spontaneous artery dissection. ..
  6. request reprint
    Pezzini A, Grassi M, Zotto E, Giossi A, Volonghi I, Costa P, et al. Do common prothrombotic mutations influence the risk of cerebral ischaemia in patients with patent foramen ovale? Systematic review and meta-analysis. Thromb Haemost. 2009;101:813-7 pubmed
    ..Addition of common prothrombotic genetic variants to standard initial screening may contribute to stratifying PFO-associated stroke patients at different risk of ischaemic events and targeting secondary prevention strategies. ..
  7. request reprint
    Pezzini A, Del Zotto E, Volonghi I, Giossi A, Costa P, Padovani A. Cerebral amyloid angiopathy: a common cause of cerebral hemorrhage. Curr Med Chem. 2009;16:2498-513 pubmed
    ..The present paper summarizes epidemiologic and clinical aspects of CAA, and highlights the presumed pathomechanisms of amyloid deposition in both sporadic and hereditary forms. ..
  8. Pezzini A, Grassi M, Del Zotto E, Lodigiani C, Ferrazzi P, Spalloni A, et al. Common genetic markers and prediction of recurrent events after ischemic stroke in young adults. Neurology. 2009;73:717-23 pubmed publisher
    ..The NRI was also significant (NRI = 0.172, test z = 2.17). Addition of common genetic variants to traditional risk factors may be an effective method for discriminating young stroke patients at different risk of future ischemic events. ..
  9. Pezzini A, Drera B, Del Zotto E, Ritelli M, Carletti M, Tomelleri G, et al. Mutations in TGFBR2 gene cause spontaneous cervical artery dissection. J Neurol Neurosurg Psychiatry. 2011;82:1372-4 pubmed publisher
    ....