Matthew D Petroski

Summary

Publications

  1. ncbi Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, California 94080, USA
    J Biol Chem 282:29936-45. 2007
  2. ncbi The ubiquitin system, disease, and drug discovery
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, CA, 94080, USA
    BMC Biochem 9:S7. 2008
  3. ncbi Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology 156 29, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Mol Cell 11:1435-44. 2003
  4. ncbi In vitro reconstitution of SCF substrate ubiquitination with purified proteins
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Methods Enzymol 398:143-58. 2005
  5. ncbi Function and regulation of cullin-RING ubiquitin ligases
    Matthew D Petroski
    Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 6:9-20. 2005
  6. ncbi Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Cell 123:1107-20. 2005

Detail Information

Publications6

  1. ncbi Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, California 94080, USA
    J Biol Chem 282:29936-45. 2007
    ....
  2. ncbi The ubiquitin system, disease, and drug discovery
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, CA, 94080, USA
    BMC Biochem 9:S7. 2008
    ..PUBLICATION HISTORY : Republished from Current BioData's Targeted Proteins database (TPdb; http://www.targetedproteinsdb.com)...
  3. ncbi Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology 156 29, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Mol Cell 11:1435-44. 2003
    ..Our results reveal that a single multiubiquitin chain can sustain a physiological turnover rate, but that chain position plays an unexpectedly significant role in the rate of proteasomal proteolysis...
  4. ncbi In vitro reconstitution of SCF substrate ubiquitination with purified proteins
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Methods Enzymol 398:143-58. 2005
    ..Based on our experience in reconstituting Sic1 ubiquitination, we suggest some parameters to consider that should be generally applicable to the study of different SCF complexes and other ubiquitin ligases...
  5. ncbi Function and regulation of cullin-RING ubiquitin ligases
    Matthew D Petroski
    Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 6:9-20. 2005
    ..In this review, we focus on the composition, regulation and function of cullin-RING ligases, and describe how these enzymes can be characterized by a set of general principles...
  6. ncbi Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Cell 123:1107-20. 2005
    ..We propose that the acidic loop favorably positions K48 of a substrate-linked ubiquitin to attack SCF bound Cdc34 approximately ubiquitin thioester and thereby enables processive synthesis of K48-linked ubiquitin chains by SCF-Cdc34...