E M J Peters

Summary

Publications

  1. ncbi Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance
    Eva M J Peters
    Department of Internal Medicine, Psychosomatics, Biomedical Research Center, Universitätsmedizin Charité, Campus Virchow Klinikum, Berlin, Germany
    J Invest Dermatol 126:1937-47. 2006
  2. ncbi Neurotrophins act as neuroendocrine regulators of skin homeostasis in health and disease
    E M J Peters
    Cutaneous Psychoneuroimmunology, Internal Medicine Psychosomatics, Charite Universitatsmedizin Berlin, Berlin, Germany
    Horm Metab Res 39:110-24. 2007
  3. ncbi Control of human hair growth by neurotrophins: brain-derived neurotrophic factor inhibits hair shaft elongation, induces catagen, and stimulates follicular transforming growth factor beta2 expression
    Eva M J Peters
    Department of Internal Medicine, Biomedical Research Center, University Medicine Charité, Campus Virchow Hospital, Berlin, Germany
    J Invest Dermatol 124:675-85. 2005
  4. pmc p75 Neurotrophin Receptor-Mediated Signaling Promotes Human Hair Follicle Regression (Catagen)
    Eva M J Peters
    Biomedical Research Center, Room No 2 0549, Charité Campus Virchow Hospital, Augustenburger Platz 1, D 13353 Berlin, Germany
    Am J Pathol 168:221-34. 2006
  5. doi Skin and hair follicle innervation in experimental models: a guide for the exact and reproducible evaluation of neuronal plasticity
    Sven Hendrix
    Institute for Cell Biology and Neurobiology, Center for Anatomy, Charite Universitatsmedizin, Berlin, Germany
    Exp Dermatol 17:214-27. 2008
  6. ncbi Neuronal plasticity and neuroregeneration in the skin -- the role of inflammation
    S Hendrix
    Institute of Cell Biology and Neurobiology, Center for Anatomy, Charite Universitatsmedizin Berlin, Charitépl 1, D 10098 Berlin, Germany
    J Neuroimmunol 184:113-26. 2007
  7. ncbi Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
    Ricarda A Joachim
    Center of Internal Medicine and Dermatology, Charite, University Medicine Berlin, Campus Virchow, Berlin, Germany
    J Mol Med (Berl) 85:1369-78. 2007
  8. ncbi Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
    Petra C Arck
    Biomedizinisches Forschungszentrum, Campus Virchow Klinikum, Charite University Medicine, Augustenburger Platz 1, 13353 Berlin, Germany
    J Mol Med (Berl) 83:386-96. 2005
  9. ncbi Topical minoxidil counteracts stress-induced hair growth inhibition in mice
    Petra Clara Arck
    Department of Internal Medicine, Charite, Humboldt University, Berlin, Germany
    Exp Dermatol 12:580-90. 2003
  10. ncbi Nerve growth factor and its precursor differentially regulate hair cycle progression in mice
    Eva M J Peters
    Biomedical Research Center, Department of Internal Medicine, Psychosomatics, University Medicine Berlin Charite, Berlin, Germany
    J Histochem Cytochem 54:275-88. 2006

Collaborators

Detail Information

Publications23

  1. ncbi Neuropeptide control mechanisms in cutaneous biology: physiological and clinical significance
    Eva M J Peters
    Department of Internal Medicine, Psychosomatics, Biomedical Research Center, Universitätsmedizin Charité, Campus Virchow Klinikum, Berlin, Germany
    J Invest Dermatol 126:1937-47. 2006
    ..Progress in this field will likely result in novel therapies for the management of diseases characterized by deregulated inflammation, tissue remodeling, angiogenesis, and neoplasm...
  2. ncbi Neurotrophins act as neuroendocrine regulators of skin homeostasis in health and disease
    E M J Peters
    Cutaneous Psychoneuroimmunology, Internal Medicine Psychosomatics, Charite Universitatsmedizin Berlin, Berlin, Germany
    Horm Metab Res 39:110-24. 2007
    ....
  3. ncbi Control of human hair growth by neurotrophins: brain-derived neurotrophic factor inhibits hair shaft elongation, induces catagen, and stimulates follicular transforming growth factor beta2 expression
    Eva M J Peters
    Department of Internal Medicine, Biomedical Research Center, University Medicine Charité, Campus Virchow Hospital, Berlin, Germany
    J Invest Dermatol 124:675-85. 2005
    ..Thus, human scalp hair follicles are both a source and target of bioregulation by BDNF, which invites to target TrkB-mediated signaling for therapeutic hair growth modulation...
  4. pmc p75 Neurotrophin Receptor-Mediated Signaling Promotes Human Hair Follicle Regression (Catagen)
    Eva M J Peters
    Biomedical Research Center, Room No 2 0549, Charité Campus Virchow Hospital, Augustenburger Platz 1, D 13353 Berlin, Germany
    Am J Pathol 168:221-34. 2006
    ....
  5. doi Skin and hair follicle innervation in experimental models: a guide for the exact and reproducible evaluation of neuronal plasticity
    Sven Hendrix
    Institute for Cell Biology and Neurobiology, Center for Anatomy, Charite Universitatsmedizin, Berlin, Germany
    Exp Dermatol 17:214-27. 2008
    ..Moreover, this method can be easily transferred to other densely innervated peripheral organs...
  6. ncbi Neuronal plasticity and neuroregeneration in the skin -- the role of inflammation
    S Hendrix
    Institute of Cell Biology and Neurobiology, Center for Anatomy, Charite Universitatsmedizin Berlin, Charitépl 1, D 10098 Berlin, Germany
    J Neuroimmunol 184:113-26. 2007
    ..Here, we review key studies on bilateral neuroimmune interactions in the skin under both healthy and disease conditions to provide a basis for future research on the role of inflammation in peripheral nerve regeneration...
  7. ncbi Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
    Ricarda A Joachim
    Center of Internal Medicine and Dermatology, Charite, University Medicine Berlin, Campus Virchow, Berlin, Germany
    J Mol Med (Berl) 85:1369-78. 2007
    ....
  8. ncbi Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
    Petra C Arck
    Biomedizinisches Forschungszentrum, Campus Virchow Klinikum, Charite University Medicine, Augustenburger Platz 1, 13353 Berlin, Germany
    J Mol Med (Berl) 83:386-96. 2005
    ..These results indicate that the cross-talk between SP and mast cell activation via NK-1R appears to be the most important pathway in the regulation of hair follicle cycling upon stress response...
  9. ncbi Topical minoxidil counteracts stress-induced hair growth inhibition in mice
    Petra Clara Arck
    Department of Internal Medicine, Charite, Humboldt University, Berlin, Germany
    Exp Dermatol 12:580-90. 2003
    ..This encourages one to explore clinically whether topical minoxidil is a safe and effective pharmacologic tool for the management of stress-associated telogen effluvium in humans...
  10. ncbi Nerve growth factor and its precursor differentially regulate hair cycle progression in mice
    Eva M J Peters
    Biomedical Research Center, Department of Internal Medicine, Psychosomatics, University Medicine Berlin Charite, Berlin, Germany
    J Histochem Cytochem 54:275-88. 2006
    ..This has important implications for the future design of specific neurotrophin receptor ligands as novel pharmaceuticals in the modification of tissue remodeling processes such as hair growth or wound healing...
  11. ncbi Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control
    Eva M J Peters
    Biomedical Research Center, Psychoneuroimmunology Research Group, Internal Medicine, Psychosomatics, University Medicine Berlin, Charité Virchow Campus, Germany
    Exp Dermatol 15:1-13. 2006
    ....
  12. ncbi Mast cell-driven skin inflammation is impaired in the absence of sensory nerves
    Frank Siebenhaar
    Department of Dermatology and Allergy, Allergie Centrum Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Allergy Clin Immunol 121:955-61. 2008
    ..However, little is known about the role of skin nerves and neuropeptides in the regulation of MC-mediated skin inflammation, and the contribution of MCs in neurogenic inflammation is still controversial...
  13. ncbi Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice
    Sanja Pavlovic
    Psycho Neuro Immunology, Center for Internal Medicine and Dermatology, Neuroscience Research Center, Charite University Medicine, Campus Mitte, Berlin, Germany
    J Invest Dermatol 128:434-46. 2008
    ....
  14. ncbi A guide to assessing damage response pathways of the hair follicle: lessons from cyclophosphamide-induced alopecia in mice
    Sven Hendrix
    Institute of Cell Biology and Neurobiology, Center of Anatomy, Charite, Humboldt University, Berlin, Germany
    J Invest Dermatol 125:42-51. 2005
    ....
  15. pmc Probing the effects of stress mediators on the human hair follicle: substance P holds central position
    Eva M J Peters
    Department of Dermatology, University Hospital Schleswig Holstein, University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Am J Pathol 171:1872-86. 2007
    ..The data obtained therewith allow one to sketch the first evidence-based biological explanation for how stress may trigger or aggravate telogen effluvium and alopecia areata...
  16. ncbi Developmental timing of hair follicle and dorsal skin innervation in mice
    Eva M J Peters
    Department of Dermatology, University Hospital Eppendorf, University of Hamburg, Hamburg D 20246, Germany
    J Comp Neurol 448:28-52. 2002
    ..This sequence of developing innervation consistently correlates with hair follicle development, indicating a close interdependence of neuronal and epithelial morphogenesis...
  17. ncbi Neurotrophins in skin biology and pathology
    Vladimir A Botchkarev
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Invest Dermatol 126:1719-27. 2006
    ....
  18. ncbi Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression
    Eva M J Peters
    Department of Dermatology, University Hospital Eppendorf, University of Hamburg, Germany
    J Histochem Cytochem 50:751-66. 2002
    ..In addition, differentiated c-Kit-IR melanocytes target the bulb, while non-c-Kit-IR melanoblasts invade the outer root sheath and bulge in fully developed hair follicles...
  19. ncbi Limitations of human occipital scalp hair follicle organ culture for studying the effects of minoxidil as a hair growth enhancer
    Markus Magerl
    Department of Biomedical Sciences, University of Bradford, Bradford, UK
    Exp Dermatol 13:635-42. 2004
    ....
  20. pmc Neuroimmunology of stress: skin takes center stage
    Petra C Arck
    Biomedical Research Center, Charite, University Medicine Berlin, Berlin, Germany
    J Invest Dermatol 126:1697-704. 2006
    ....
  21. ncbi Kit is expressed by epithelial cells in vivo
    Eva M J Peters
    Department of Dermatology, University Hospital Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
    J Invest Dermatol 121:976-84. 2003
    ..The expression of Kit in the most rapidly proliferating compartment of the hair follicle epithelium suggests intriguing, as yet unexplored new functions of Kit signaling in epithelial cell biology...
  22. ncbi Analysis of hair follicles in mutant laboratory mice
    John P Sundberg
    The Jackson Laboratory, Bar Harbor, Maine 04609 1500, USA
    J Investig Dermatol Symp Proc 10:264-70. 2005
    ..A variety of systematic approaches to analysis of the pilosebacous unit are provided here...
  23. ncbi Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata)
    Frank Siebenhaar
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Invest Dermatol 127:1489-97. 2007
    ..These data suggest that SP, NEP, and NK-1R serve as important regulators in the molecular signaling network modulating inflammatory response in autoimmune hair loss...