Julio Rubio

Summary

Affiliation: Universidad Peruana Cayetano Heredia
Country: Peru

Publications

  1. ncbi Lepidium meyenii (Maca) reversed the lead acetate induced -- damage on reproductive function in male rats
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Food Chem Toxicol 44:1114-22. 2006
  2. ncbi Aqueous and hydroalcoholic extracts of Black Maca (Lepidium meyenii) improve scopolamine-induced memory impairment in mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    Food Chem Toxicol 45:1882-90. 2007
  3. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006
  4. ncbi Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Lima, Peru
    Fertil Steril 89:1461-7. 2008
  5. ncbi Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats
    Carla Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    J Ethnopharmacol 103:448-54. 2006
  6. ncbi Dose-response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats
    Francisco Chung
    Department of Biological and Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    J Ethnopharmacol 98:143-7. 2005
  7. pmc Lepidium meyenii (Maca) increases litter size in normal adult female mice
    Ana C Ruiz-Luna
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:16. 2005
  8. pmc Red maca (Lepidium meyenii) reduced prostate size in rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:5. 2005
  9. doi Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
    Karina Paola Leiva
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Peru
    Toxicol Mech Methods 21:495-502. 2011
  10. doi Effects of different varieties of Maca (Lepidium meyenii) on bone structure in ovariectomized rats
    Carla Gonzales
    Biological and Physiological Science Department, Universidad Peruana Cayetano Heredia, Lima, Peru
    Forsch Komplementmed 17:137-43. 2010

Collaborators

Detail Information

Publications18

  1. ncbi Lepidium meyenii (Maca) reversed the lead acetate induced -- damage on reproductive function in male rats
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Food Chem Toxicol 44:1114-22. 2006
    ..Maca prevented LA-induced spermatogenic disruption in rats and it may become in a potential treatment of male infertility associated with lead exposure...
  2. ncbi Aqueous and hydroalcoholic extracts of Black Maca (Lepidium meyenii) improve scopolamine-induced memory impairment in mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    Food Chem Toxicol 45:1882-90. 2007
    ..Black Maca extracts inhibited AChE activity, whereas MAO activity was not affected. These results indicate that Black Maca improves scopolamine-induced memory deficits...
  3. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006
    ..Maca is a cultivated plant and different cultivars are described according to the color of the hypocotyls...
  4. ncbi Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Lima, Peru
    Fertil Steril 89:1461-7. 2008
    ..To evaluate the effect of different fractions of Black Maca (Lepidium meyenii), obtained from the hydroalcoholic extract, on spermatogenesis...
  5. ncbi Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats
    Carla Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    J Ethnopharmacol 103:448-54. 2006
    ..In conclusion, there were differences in the biological response of the three ecotypes of Maca (Yellow, Red and Black). Black Maca appeared to have more beneficial effect on sperm counts and epididymal sperm motility...
  6. ncbi Dose-response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats
    Francisco Chung
    Department of Biological and Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    J Ethnopharmacol 98:143-7. 2005
    ..2 g dry Maca hypocotyls/kg...
  7. pmc Lepidium meyenii (Maca) increases litter size in normal adult female mice
    Ana C Ruiz-Luna
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:16. 2005
    ..The present study was aimed to investigate the effects of Maca on several fertility parameters of female mice at reproductive age...
  8. pmc Red maca (Lepidium meyenii) reduced prostate size in rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:5. 2005
    ..The absolute content of glucosinolates in Maca hypocotyls is relatively higher than that reported in other cruciferous crops. Therefore, Maca may have proapoptotic and anti-proliferative effects in the prostate...
  9. doi Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate
    Karina Paola Leiva
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Peru
    Toxicol Mech Methods 21:495-502. 2011
    ..EEP showed an antioxidant activity similar to that of AA. EEP prevented LA-induced spermatogenic disruption in rats and its antioxidant activity could explain its capacity to reverse the damage produced by LA on spermatogenesis...
  10. doi Effects of different varieties of Maca (Lepidium meyenii) on bone structure in ovariectomized rats
    Carla Gonzales
    Biological and Physiological Science Department, Universidad Peruana Cayetano Heredia, Lima, Peru
    Forsch Komplementmed 17:137-43. 2010
    ..This study was designed to determine the effect of different varieties of maca (Lepidium meyenii) on bone structure in ovariectomized (OVX) rats...
  11. doi Dose-response effect of black maca (Lepidium meyenii) in mice with memory impairment induced by ethanol
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Toxicol Mech Methods 21:628-34. 2011
    ..Correlation analyses showed that the effect of BM a dose-dependent behavior. Finally, BM improved experimental memory impairment induced by ethanol in a dose-response manner due, in part, to its content of polyphenolic compounds...
  12. ncbi Effect of alcoholic extract of Lepidium meyenii (Maca) on testicular function in male rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    Asian J Androl 5:349-52. 2003
    ..To evaluate the effect of the alcoholic extract of Lepidium meyenii (Maca) on the spermatogenesis in male rats...
  13. pmc Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Environ Health 7:59. 2008
    ..We performed a cross-sectional study of associations between dialkylphosphate metabolites of organophosphates and semen quality among pesticide applicators in Majes (Arequipa), Peru...
  14. ncbi Semen quality and reproductive sex hormone levels in Peruvian pesticide sprayers
    Sandra Yucra
    Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Occup Environ Health 12:355-61. 2006
    ..These findings provide further evidence that occupational exposures to OP pesticides adversely affect semen quality and sex hormones...
  15. pmc Chronic mountain sickness score was related with health status score but not with hemoglobin levels at high altitudes
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru
    Respir Physiol Neurobiol 188:152-60. 2013
    ..Health status score was significantly higher in subjects without CMS. In conclusion, elevated hemoglobin levels were not associated with elevated CMS clinical score...
  16. doi High serum zinc and serum testosterone levels were associated with excessive erythrocytosis in men at high altitudes
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Endocrine 40:472-80. 2011
    ..In conclusion, higher serum testosterone levels and Zn levels were associated with EE, and low scores of signs/symptoms of CMS were associated with higher Zn and nitric oxide levels...
  17. ncbi [Maca (Lepidium meyenii Walp), a review of its biological properties]
    Gustavo F Gonzales
    Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Peru Med Exp Salud Publica 31:100-10. 2014
    ..Although experimental studies have shown that maca has diverse beneficial effects, more clinical studies are needed to confirm these results. ..
  18. ncbi Effect of letrozole at 2.5 mg or 5.0 mg/day on ovarian stimulation with gonadotropins in women undergoing intrauterine insemination
    Luis Noriega-Portella
    PRANOR, Group of Assisted Reproduction, Universidad Peruana Cayetano Heredia, Lima, Peru
    Fertil Steril 90:1818-25. 2008
    ..To determine the effect of combined therapy of letrozole (2.5 mg or 5.0 mg) with recombinant follicle-stimulating hormone (FSH) in comparison with the administration of recombinant FSH alone in an intrauterine insemination (IUI) program...