G F Gonzales

Summary

Affiliation: Universidad Peruana Cayetano Heredia
Country: Peru

Publications

  1. pmc Lepidium meyenii (Maca) increases litter size in normal adult female mice
    Ana C Ruiz-Luna
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:16. 2005
  2. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006
  3. ncbi Update on the impact of Chlamydia trachomatis infection on male fertility
    G F Gonzales
    Department of Biological and Physiological Sciences and Laboratories of Investigation and Development, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 36:1-23. 2004
  4. ncbi Cycloheximide prevents production of arresting, a fraction of 30-50 kDa obtained from seminiferous tubule conditioned medium
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Asian J Androl 6:359-64. 2004
  5. pmc Red maca (Lepidium meyenii) reduced prostate size in rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:5. 2005
  6. ncbi Stillbirth rates in Peruvian populations at high altitude
    Gustavo F Gonzales
    High Altitude Research Institute, Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Gynaecol Obstet 100:221-7. 2008
  7. pmc Arterial oxygen saturation in healthy newborns delivered at term in Cerro de Pasco (4340 m) and Lima (150 m)
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Av, Honorio Delgado 430, Urb, Ingenieria, Lima, Peru, PO Box 1843, Lima, Peru
    Reprod Biol Endocrinol 3:46. 2005
  8. ncbi Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia
    Gustavo F Gonzales
    Biological and Physiological Sciences, Cayetano Heredia University, Lima, Peru
    Asian J Androl 9:245-51. 2007
  9. ncbi Medicinal plants from Peru: a review of plants as potential agents against cancer
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Anticancer Agents Med Chem 6:429-44. 2006
  10. ncbi Peruvian contributions to the study on human reproduction at high altitude: from the chronicles of the Spanish conquest to the present
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura High Altitude Research Institute and Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 31, Peru
    Respir Physiol Neurobiol 158:172-9. 2007

Collaborators

Detail Information

Publications57

  1. pmc Lepidium meyenii (Maca) increases litter size in normal adult female mice
    Ana C Ruiz-Luna
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:16. 2005
    ..The present study was aimed to investigate the effects of Maca on several fertility parameters of female mice at reproductive age...
  2. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006
    ..Maca is a cultivated plant and different cultivars are described according to the color of the hypocotyls...
  3. ncbi Update on the impact of Chlamydia trachomatis infection on male fertility
    G F Gonzales
    Department of Biological and Physiological Sciences and Laboratories of Investigation and Development, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 36:1-23. 2004
    ..There is still controversial results. In future studies, function of the seminal vesicles and evaluation of the antioxidant capacity should be taken into account when role of C. trachomatis infection on male fertility is assessed...
  4. ncbi Cycloheximide prevents production of arresting, a fraction of 30-50 kDa obtained from seminiferous tubule conditioned medium
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Asian J Androl 6:359-64. 2004
    ..To evaluate the effect of a protein synthesis inhibitor cycloheximide on arresting activity in spermatogenesis and sperm count in male rats...
  5. pmc Red maca (Lepidium meyenii) reduced prostate size in rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:5. 2005
    ..The absolute content of glucosinolates in Maca hypocotyls is relatively higher than that reported in other cruciferous crops. Therefore, Maca may have proapoptotic and anti-proliferative effects in the prostate...
  6. ncbi Stillbirth rates in Peruvian populations at high altitude
    Gustavo F Gonzales
    High Altitude Research Institute, Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Gynaecol Obstet 100:221-7. 2008
    ..To compare the stillbirth rates in 4 cities at different altitudes in Peru...
  7. pmc Arterial oxygen saturation in healthy newborns delivered at term in Cerro de Pasco (4340 m) and Lima (150 m)
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Av, Honorio Delgado 430, Urb, Ingenieria, Lima, Peru, PO Box 1843, Lima, Peru
    Reprod Biol Endocrinol 3:46. 2005
    ....
  8. ncbi Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia
    Gustavo F Gonzales
    Biological and Physiological Sciences, Cayetano Heredia University, Lima, Peru
    Asian J Androl 9:245-51. 2007
    ..To determine the effect of two different extracts of red maca in male rats...
  9. ncbi Medicinal plants from Peru: a review of plants as potential agents against cancer
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Anticancer Agents Med Chem 6:429-44. 2006
    ..In addition, this review will discuss areas requiring future study and the inherent limitations in their experimental use as anti-cancer agents...
  10. ncbi Peruvian contributions to the study on human reproduction at high altitude: from the chronicles of the Spanish conquest to the present
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura High Altitude Research Institute and Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 31, Peru
    Respir Physiol Neurobiol 158:172-9. 2007
    ..Clearly, antiquity and genetics are important components in determining survival and quality of life at high altitude...
  11. ncbi Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)
    G F Gonzales
    Instituto de Investigaciones de la Altura, and Departamento de Ciencias Biológicas y Fisiológicas, Facultad de Ciencas y Filosofia, Universidad Peruana Cayetano Heredia, PO Box 1843, Lima, Peru
    J Endocrinol 180:87-95. 2004
    ..49 +/- 43.67x10(6) sperm). In conclusion, treatment of rats with Maca at high altitude prevented high altitude-induced spermatogenic disruption...
  12. ncbi Effect of alcoholic extract of Lepidium meyenii (Maca) on testicular function in male rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    Asian J Androl 5:349-52. 2003
    ..To evaluate the effect of the alcoholic extract of Lepidium meyenii (Maca) on the spermatogenesis in male rats...
  13. ncbi Effect of neonatal administration of an antidopaminergic drug (metoclopramide) on sexual behavior of male rats
    G F Gonzales
    Instituto de Investigaciones de la Altura and Department of Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Arch Androl 45:137-42. 2000
    ..01). There is strong evidence that metoclopramide neonatally administered inhibits male sexual behavior in adult rats. Dopamine may be implicated in the process of neonatal brain sexual differentiation...
  14. ncbi Function of seminal vesicles and their role on male fertility
    G F Gonzales
    Department of Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Asian J Androl 3:251-8. 2001
    ..In conclusion, the function of seminal vesicle is important for fertility. Parameters as sperm motility, sperm chromatin stability, and immuno-protection may be changed in case of its hypofunction...
  15. ncbi Lepidium meyenii (Maca) improved semen parameters in adult men
    G F Gonzales
    Department of Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Asian J Androl 3:301-3. 2001
    ..The present study was designed to determine the effect of a 4-month oral treatment with tablets of Lepidium meyenii (Maca) on seminal analysis in nine adult normal men aged 24-44 years old...
  16. ncbi Effect of Lepidium meyenii (maca) roots on spermatogenesis of male rats
    G F Gonzales
    Department of Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Asian J Androl 3:231-3. 2001
    ..To determine the effect of oral administration of an aqueous extract from the roots of Lepidium meyenii (maca) on spermatogenesis in adult male rats...
  17. ncbi True corrected seminal fructose level: a better marker of the function of seminal vesicles in infertile men
    G F Gonzales
    Instituto de Investigaciones de la Altura and Department of Physiological Sciences, Universidad Peruana Cayetano Heredia, P O 1843, Lima, Peru
    Int J Androl 24:255-60. 2001
    ..05; p: NS). In conclusion, true corrected fructose measurement relates with sperm motility in cases of asthenozoospermia. Asthenozoospermia improves with clomiphene treatment if seminal vesicle function improves after treatment...
  18. ncbi Adrenopause or decline of serum adrenal androgens with age in women living at sea level or at high altitude
    G F Gonzales
    Department of Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PO Box 1843, Lima, Peru
    J Endocrinol 173:95-101. 2002
    ..0001). In conclusion, adrenopause is attained earlier and is of greater magnitude at high altitude than at sea level...
  19. ncbi Basal serum testosterone as an indicator of response to clomiphene treatment in human epididymis, seminal vesicles and prostate
    G F Gonzales
    Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 34:308-16. 2002
    ..An absence of response was observed in cases with history of STD/leukocytospermia or hypoandrogenism...
  20. ncbi Low pulse oxygen saturation in post-menopausal women at high altitude is related to a high serum testosterone/estradiol ratio
    G F Gonzales
    Department of Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, and Hospital Nacional Cayetano Heredia, Lima, Peru
    Int J Gynaecol Obstet 71:147-54. 2000
    ..The present study was designed to determine if low pulse oxygen saturation (SpO(2)) in post-menopausal women at high altitude was related to high serum testosterone/estradiol (T/E(2)) ratio...
  21. ncbi Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men
    G F Gonzales
    Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 34:367-72. 2002
    ..In conclusion, treatment with Maca improved sexual desire...
  22. ncbi Dose-response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats
    Francisco Chung
    Department of Biological and Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    J Ethnopharmacol 98:143-7. 2005
    ..2 g dry Maca hypocotyls/kg...
  23. doi Tropaeolum tuberosum (Mashua) reduces testicular function: effect of different treatment times
    I Cárdenas-Valencia
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 40:352-7. 2008
    ..Finally, mashua reduces testicular function after one spermatogenic cycle by reducing spermatid and sperm number, DSP and epididymal sperm transit time...
  24. ncbi Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men
    G F Gonzales
    Instituto de Investigaciones de la Altura, and Department of Biological and Physiological Sciences Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, PO 1843, Lima, Peru
    J Endocrinol 176:163-8. 2003
    ..In conclusion, treatment with Maca does not affect serum reproductive hormone levels...
  25. doi Effect of red maca (Lepidium meyenii) on prostate zinc levels in rats with testosterone-induced prostatic hyperplasia
    C Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 44:362-9. 2012
    ..Also, this experimental model could be used as accurately assay to determine the effect of maca obtained under different conditions and/or the effect of different products based on maca...
  26. doi Aromatase activity after a short-course of letrozole administration in adult men at sea level and at high altitude (with or without excessive erythrocytosis)
    G F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Horm Metab Res 44:140-5. 2012
    ..In conclusion, higher serum testosterone levels in men with excessive erythrocytosis were associated with an increased rate of conversion from DHEAS to testosterone rather than to a lower aromatase activity...
  27. ncbi Effect of Black maca (Lepidium meyenii) on one spermatogenic cycle in rats
    G F Gonzales
    Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 38:166-72. 2006
    ..Testicular testosterone was not affected after 7 days treatment with Black maca. In conclusion, Black maca affects sperm count as early as 1 day after beginning of treatment...
  28. ncbi Dose-response effect of Red Maca (Lepidium meyenii) on benign prostatic hyperplasia induced by testosterone enanthate
    M Gasco
    Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Phytomedicine 14:460-4. 2007
    ..In conclusion, Red Maca administered orally in rats seems to exert an inhibitory effect at a level post DHT conversion, on the BPH-induced experimentally, although a direct measure of reductase action would still be required...
  29. ncbi Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats
    Carla Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    J Ethnopharmacol 103:448-54. 2006
    ..In conclusion, there were differences in the biological response of the three ecotypes of Maca (Yellow, Red and Black). Black Maca appeared to have more beneficial effect on sperm counts and epididymal sperm motility...
  30. doi Resistance of sperm motility to serum testosterone in men with excessive erythrocytosis at high altitude
    G F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Horm Metab Res 44:987-92. 2012
    ..In conclusion, low sperm motility was observed in men with EE despite elevated serum testosterone levels suggesting a resistance of sperm motility...
  31. ncbi Effect of high altitude exposure on spermatogenesis and epididymal sperm count in male rats
    M Gasco
    Department of Biological and Physiological Sciences, Laboratory of Investigation and Development, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 35:368-74. 2003
    ..In conclusion, high altitude exposure affects spermatogenesis, particularly onset of mitosis and spermiation. This in turn affects epididymal sperm count...
  32. ncbi Effect of chronic treatment with three varieties of Lepidium meyenii (Maca) on reproductive parameters and DNA quantification in adult male rats
    M Gasco
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 39:151-8. 2007
    ..In conclusion, Yellow and Black Maca increased epididymal sperm count after 84 days of treatment without affecting DSP. Maca seems to act as a modulator of sperm count at the reproductive tract level...
  33. doi Evaluation of different doses of mashua (Tropaeolum tuberosum) on the reduction of sperm production, motility and morphology in adult male rats
    J Leiva-Revilla
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 44:205-12. 2012
    ..Finally, lower doses mashua reduces sperm number and quality (motility and morphology), and these adverse effects on male reproductive system may be reversible after 24 days after cessation of the treatment...
  34. doi Antagonistic effect of Lepidium meyenii (red maca) on prostatic hyperplasia in adult mice
    G F Gonzales
    Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 40:179-85. 2008
    ..The reduction in prostatic stroma area by RM was 1.42 times. RM has an anti-hyperplastic effect on the prostate of adult mice when hyperplasia was induced with TE acting first at prostatic stromal level...
  35. doi Serum testosterone levels and score of chronic mountain sickness in Peruvian men natives at 4340 m
    G F Gonzales
    Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 43:189-95. 2011
    ..Some symptoms of CMS as sleep disorders and paraesthesia were more related to high serum T level; cyanosis was more related to higher haemoglobin values. In conclusion, higher serum T levels were associated to higher scores of CMS...
  36. ncbi Transillumination to evaluate spermatogenesis: effect of testosterone enanthate in adult male rats
    A Almenara
    Instituto de Investigaciones de la Altura and Department of Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Arch Androl 46:21-7. 2001
    ....
  37. doi Effects of different varieties of Maca (Lepidium meyenii) on bone structure in ovariectomized rats
    Carla Gonzales
    Biological and Physiological Science Department, Universidad Peruana Cayetano Heredia, Lima, Peru
    Forsch Komplementmed 17:137-43. 2010
    ..This study was designed to determine the effect of different varieties of maca (Lepidium meyenii) on bone structure in ovariectomized (OVX) rats...
  38. ncbi Birth weight at high altitudes in Peru
    S Hartinger
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru
    Int J Gynaecol Obstet 93:275-81. 2006
    ..To determine whether birth weights are lower at high altitudes, and whether gestational age at birth and a population's length of residence mitigate the effect of high altitude...
  39. pmc High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Alberto Cazorla Tálleri Universidad Peruana Cayetano Heredia, Ave Honorio Delgado 430, Lima 31, Peru
    Am J Physiol Endocrinol Metab 296:E1319-25. 2009
    ..In conclusion, high androgen activity could be involved in the etiopathogeny of CMS. This evidence provides an opportunity to develop new therapeutic strategies...
  40. doi Birth weight charts for gestational age in 63,620 healthy infants born in Peruvian public hospitals at low and at high altitude
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Acta Paediatr 98:454-8. 2009
    ..To construct distribution curves for birth weight, length and head circumference using a large sample of infants born at low (150 m) and high (3000-4400 m) altitude...
  41. doi Lepidium meyenii (Maca): a plant from the highlands of Peru--from tradition to science
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura, and Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Forsch Komplementmed 16:373-80. 2009
    ..The exact mechanisms of action are still unclear, but so far research clearly indicates that various bioactive constituents contribute to the clinical effects reported...
  42. pmc Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Environ Health 7:59. 2008
    ..We performed a cross-sectional study of associations between dialkylphosphate metabolites of organophosphates and semen quality among pesticide applicators in Majes (Arequipa), Peru...
  43. pmc The Methyltetrahydro-{beta}-Carbolines in Maca (Lepidium meyenii)
    Gustavo F Gonzales
    Av Honorio Delgado 430, Lima 31, Peru
    Evid Based Complement Alternat Med 6:315-6. 2009
    ..We present evidence that MTCA is a natural constituent of Maca, and on consumption no toxicity is found. This suggests that, when consumed as multi-component, MTCA may loose its adversity as drug action...
  44. doi Hypocotyls of Lepidium meyenii (maca), a plant of the Peruvian highlands, prevent ultraviolet A-, B-, and C-induced skin damage in rats
    Cynthia Gonzales-Castañeda
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Photodermatol Photoimmunol Photomed 24:24-31. 2008
    ..Lepidium meyenii (maca) is a plant that grows exclusively in the Peruvian Central Andes, where ultraviolet radiation (UVR) is predominant. Objective: Determine if two extracts of maca can provide dermal protection against UVR...
  45. ncbi Mercury exposures in informal gold miners and relatives in southern Peru
    Jasmin Hurtado
    Department of Micdrobiology, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Av Honorio Delgado N 430 Lima 31, Apartado Postal 4314, Lima 100, Peru
    Int J Occup Environ Health 12:340-5. 2006
    ..5 microg/m3 (12-55) during amalgamation, and 12 microg/m3 (3-23) in the mining town. Smelters are highly contaminated with mercury, as are the people living around smelters...
  46. ncbi Lepidium meyenii (Maca) reversed the lead acetate induced -- damage on reproductive function in male rats
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Food Chem Toxicol 44:1114-22. 2006
    ..Maca prevented LA-induced spermatogenic disruption in rats and it may become in a potential treatment of male infertility associated with lead exposure...
  47. ncbi Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Lima, Peru
    Fertil Steril 89:1461-7. 2008
    ..To evaluate the effect of different fractions of Black Maca (Lepidium meyenii), obtained from the hydroalcoholic extract, on spermatogenesis...
  48. ncbi Aqueous and hydroalcoholic extracts of Black Maca (Lepidium meyenii) improve scopolamine-induced memory impairment in mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    Food Chem Toxicol 45:1882-90. 2007
    ..Black Maca extracts inhibited AChE activity, whereas MAO activity was not affected. These results indicate that Black Maca improves scopolamine-induced memory deficits...
  49. ncbi Semen quality and reproductive sex hormone levels in Peruvian pesticide sprayers
    Sandra Yucra
    Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Occup Environ Health 12:355-61. 2006
    ..These findings provide further evidence that occupational exposures to OP pesticides adversely affect semen quality and sex hormones...
  50. ncbi Blood lead levels among police officers in Lima and Callao, 2004
    Wilfredo Mormontoy
    Departament of Statistics, Demography, Humanity and Social Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Hyg Environ Health 209:497-502. 2006
    ..This may be a consequence of the policy to eliminate leaded gasoline in Peru. However, it is still necessary to monitor this policy to ensure the elimination of lead in gasoline...
  51. pmc Maternal hemoglobin level and fetal outcome at low and high altitudes
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Physiol Regul Integr Comp Physiol 297:R1477-85. 2009
    ..Our data suggest, that maternal hemoglobin above 11 g/dl but below 13 g/dl is the area of minimal risk of poor adverse outcomes. Living at HA had an adverse effect independent of hemoglobin level...
  52. pmc Sperm chromatin stability and its relationship with fertilization rate after intracytoplasmic sperm injection (ICSI) in an assisted reproduction program
    Javier Garcia
    Laboratory of Assisted Reproduction, PRANOR Group of Assisted Reproduction, Instituto de Ginecología y Reproducción, Lima, Peru
    J Assist Reprod Genet 24:587-93. 2007
    ..Evaluate sperm chromatin stability and its relationship with the rate of fertilization after procedures of intracytoplasmic sperm injection (ICSI) in a program of assisted reproduction...
  53. ncbi Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice
    Eduardo Bustos-Obregon
    Faculty of Medicine, University of Chile, Independencia 1027 P O Box 70061, Santiago 7, Chile
    Asian J Androl 7:71-6. 2005
    ..To observe the effect of the aqueous extract of hypocotyls of the plant Lepidium meyenii (Maca) on spermatogenic damage induced by the organophosphate insecticide malathion in mice...
  54. ncbi Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis
    Luis G Valerio
    Division of Biotechnology and GRAS Notice Review, Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, Maryland 20740, USA
    Toxicol Rev 24:11-35. 2005
    ....
  55. ncbi Heart mitochondrial nitric oxide synthase is upregulated in male rats exposed to high altitude (4,340 m)
    Gustavo F Gonzales
    Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Junin 956, C1113AAD, Buenos Aires, Argentina
    Am J Physiol Heart Circ Physiol 288:H2568-73. 2005
    ..We conclude that high altitude triggers a physiological adaptive response that upregulates heart mtNOS activity and is associated in an opposed manner with the serum levels of testosterone and estradiol...
  56. ncbi Lead exposure and semen quality among traffic police in Arequipa, Peru
    Lynn Eibensteiner
    Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Int J Occup Environ Health 11:161-6. 2005
    ..The results should be interpreted cautiously since the numbers were small and the analysis was unable to control for all potential confounders due to incomplete data...
  57. ncbi Mitochondrial contribution to the molecular mechanism of heart acclimatization to chronic hypoxia: role of nitric oxide
    Tamara Zaobornyj
    Laboratory of Free Radical Biology, School of Pharmacy and Biochemistry, University of Buenos Aires, C1113AAD, Buenos Aires, Argentina
    Front Biosci 12:1247-59. 2007
    ..Along with classical parameters, we consider NO, specially that generated by mtNOS, mitochondrial respiratory chain, mitoK(ATP) channels, reactive oxygen species and control of gene expression by HIF-1...