Manuel Gasco

Summary

Affiliation: Universidad Peruana Cayetano Heredia
Country: Peru

Publications

  1. ncbi Effect of chronic treatment with three varieties of Lepidium meyenii (Maca) on reproductive parameters and DNA quantification in adult male rats
    M Gasco
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 39:151-8. 2007
  2. ncbi Dose-response effect of Red Maca (Lepidium meyenii) on benign prostatic hyperplasia induced by testosterone enanthate
    M Gasco
    Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Phytomedicine 14:460-4. 2007
  3. ncbi Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Lima, Peru
    Fertil Steril 89:1461-7. 2008
  4. ncbi Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats
    Carla Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    J Ethnopharmacol 103:448-54. 2006
  5. ncbi Dose-response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats
    Francisco Chung
    Department of Biological and Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    J Ethnopharmacol 98:143-7. 2005
  6. ncbi Lepidium meyenii (Maca) reversed the lead acetate induced -- damage on reproductive function in male rats
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Food Chem Toxicol 44:1114-22. 2006
  7. pmc Role of maca (Lepidium meyenii) consumption on serum interleukin-6 levels and health status in populations living in the Peruvian Central Andes over 4000 m of altitude
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430 Lima 31, Lima, Peru
    Plant Foods Hum Nutr 68:347-51. 2013
  8. doi High serum zinc and serum testosterone levels were associated with excessive erythrocytosis in men at high altitudes
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Endocrine 40:472-80. 2011
  9. ncbi Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia
    Gustavo F Gonzales
    Biological and Physiological Sciences, Cayetano Heredia University, Lima, Peru
    Asian J Androl 9:245-51. 2007
  10. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006

Detail Information

Publications25

  1. ncbi Effect of chronic treatment with three varieties of Lepidium meyenii (Maca) on reproductive parameters and DNA quantification in adult male rats
    M Gasco
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Andrologia 39:151-8. 2007
    ..In conclusion, Yellow and Black Maca increased epididymal sperm count after 84 days of treatment without affecting DSP. Maca seems to act as a modulator of sperm count at the reproductive tract level...
  2. ncbi Dose-response effect of Red Maca (Lepidium meyenii) on benign prostatic hyperplasia induced by testosterone enanthate
    M Gasco
    Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Phytomedicine 14:460-4. 2007
    ..In conclusion, Red Maca administered orally in rats seems to exert an inhibitory effect at a level post DHT conversion, on the BPH-induced experimentally, although a direct measure of reductase action would still be required...
  3. ncbi Effect of different fractions from hydroalcoholic extract of Black Maca (Lepidium meyenii) on testicular function in adult male rats
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Lima, Peru
    Fertil Steril 89:1461-7. 2008
    ..To evaluate the effect of different fractions of Black Maca (Lepidium meyenii), obtained from the hydroalcoholic extract, on spermatogenesis...
  4. ncbi Effect of short-term and long-term treatments with three ecotypes of Lepidium meyenii (MACA) on spermatogenesis in rats
    Carla Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, P O Box 1843, Lima, Peru
    J Ethnopharmacol 103:448-54. 2006
    ..In conclusion, there were differences in the biological response of the three ecotypes of Maca (Yellow, Red and Black). Black Maca appeared to have more beneficial effect on sperm counts and epididymal sperm motility...
  5. ncbi Dose-response effects of Lepidium meyenii (Maca) aqueous extract on testicular function and weight of different organs in adult rats
    Francisco Chung
    Department of Biological and Physiological Sciences and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    J Ethnopharmacol 98:143-7. 2005
    ..2 g dry Maca hypocotyls/kg...
  6. ncbi Lepidium meyenii (Maca) reversed the lead acetate induced -- damage on reproductive function in male rats
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Food Chem Toxicol 44:1114-22. 2006
    ..Maca prevented LA-induced spermatogenic disruption in rats and it may become in a potential treatment of male infertility associated with lead exposure...
  7. pmc Role of maca (Lepidium meyenii) consumption on serum interleukin-6 levels and health status in populations living in the Peruvian Central Andes over 4000 m of altitude
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430 Lima 31, Lima, Peru
    Plant Foods Hum Nutr 68:347-51. 2013
    ..05). In conclusion, consumption of maca was associated with low serum IL-6 levels and in turn with better health status scores in the SF-20 survey and low chronic mountain sickness scores. ..
  8. doi High serum zinc and serum testosterone levels were associated with excessive erythrocytosis in men at high altitudes
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Endocrine 40:472-80. 2011
    ..In conclusion, higher serum testosterone levels and Zn levels were associated with EE, and low scores of signs/symptoms of CMS were associated with higher Zn and nitric oxide levels...
  9. ncbi Effect of two different extracts of red maca in male rats with testosterone-induced prostatic hyperplasia
    Gustavo F Gonzales
    Biological and Physiological Sciences, Cayetano Heredia University, Lima, Peru
    Asian J Androl 9:245-51. 2007
    ..To determine the effect of two different extracts of red maca in male rats...
  10. pmc Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    BMC Complement Altern Med 6:23. 2006
    ..Maca is a cultivated plant and different cultivars are described according to the color of the hypocotyls...
  11. doi Maternal hemoglobin concentration and adverse pregnancy outcomes at low and moderate altitudes in Peru
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Lima, Peru
    J Matern Fetal Neonatal Med 25:1105-10. 2012
    ..To identify associations of maternal hemoglobin (Hb) with perinatal outcomes at low and moderate altitudes in Peru...
  12. pmc Red maca (Lepidium meyenii) reduced prostate size in rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:5. 2005
    ..The absolute content of glucosinolates in Maca hypocotyls is relatively higher than that reported in other cruciferous crops. Therefore, Maca may have proapoptotic and anti-proliferative effects in the prostate...
  13. pmc Chronic mountain sickness score was related with health status score but not with hemoglobin levels at high altitudes
    Gustavo F Gonzales
    Instituto de Investigaciones de la Altura, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru
    Respir Physiol Neurobiol 188:152-60. 2013
    ..Health status score was significantly higher in subjects without CMS. In conclusion, elevated hemoglobin levels were not associated with elevated CMS clinical score...
  14. doi Association of hemoglobin values at booking with adverse maternal outcomes among Peruvian populations living at different altitudes
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Gynaecol Obstet 117:134-9. 2012
    ..To determine hemoglobin values associated with adverse maternal outcomes among Peruvian populations at different altitudes...
  15. ncbi Effect of alcoholic extract of Lepidium meyenii (Maca) on testicular function in male rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Postal Office 1843, Lima, Peru
    Asian J Androl 5:349-52. 2003
    ..To evaluate the effect of the alcoholic extract of Lepidium meyenii (Maca) on the spermatogenesis in male rats...
  16. doi Dose-response effect of black maca (Lepidium meyenii) in mice with memory impairment induced by ethanol
    Julio Rubio
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
    Toxicol Mech Methods 21:628-34. 2011
    ..Correlation analyses showed that the effect of BM a dose-dependent behavior. Finally, BM improved experimental memory impairment induced by ethanol in a dose-response manner due, in part, to its content of polyphenolic compounds...
  17. pmc Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters
    Sandra Yucra
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Environ Health 7:59. 2008
    ..We performed a cross-sectional study of associations between dialkylphosphate metabolites of organophosphates and semen quality among pesticide applicators in Majes (Arequipa), Peru...
  18. ncbi Semen quality and reproductive sex hormone levels in Peruvian pesticide sprayers
    Sandra Yucra
    Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Int J Occup Environ Health 12:355-61. 2006
    ..These findings provide further evidence that occupational exposures to OP pesticides adversely affect semen quality and sex hormones...
  19. doi A mixture of extracts from Peruvian plants (black maca and yacon) improves sperm count and reduced glycemia in mice with streptozotocin-induced diabetes
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences and Laboratory of Investigation and Development LID, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Toxicol Mech Methods 23:509-18. 2013
    ..In summary, streptozotocin-induced diabetes resulted in reduction in sperm counts and liver damage. These effects could be reduced with BM, yacon and the BM+yacon mixture...
  20. pmc Lepidium meyenii (Maca) increases litter size in normal adult female mice
    Ana C Ruiz-Luna
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru
    Reprod Biol Endocrinol 3:16. 2005
    ..The present study was aimed to investigate the effects of Maca on several fertility parameters of female mice at reproductive age...
  21. ncbi The transillumination technique as a method for the assessment of spermatogenesis using medicinal plants: the effect of extracts of black maca (Lepidium meyenii) and camu camu (Myrciaria dubia) on stages of the spermatogenic cycle in male rats
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Peru and
    Toxicol Mech Methods 23:559-65. 2013
    ..This technique is becoming increasingly a useful tool for assessment spermatogenesis...
  22. ncbi [Maternal hemoglobin in Peru: regional differences and its association with adverse perinatal outcomes]
    Gustavo F Gonzales
    Departamento de Ciencias Biológicas y Fisiológicas, Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Peru Med Exp Salud Publica 28:484-91. 2011
    ....
  23. pmc High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men
    Gustavo F Gonzales
    Laboratory of Endocrinology and Reproduction, Faculty of Sciences and Philosophy, Alberto Cazorla Tálleri Universidad Peruana Cayetano Heredia, Ave Honorio Delgado 430, Lima 31, Peru
    Am J Physiol Endocrinol Metab 296:E1319-25. 2009
    ..In conclusion, high androgen activity could be involved in the etiopathogeny of CMS. This evidence provides an opportunity to develop new therapeutic strategies...
  24. ncbi [Maca (Lepidium meyenii Walp), a review of its biological properties]
    Gustavo F Gonzales
    Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano Heredia, Lima, Peru
    Rev Peru Med Exp Salud Publica 31:100-10. 2014
    ..Although experimental studies have shown that maca has diverse beneficial effects, more clinical studies are needed to confirm these results. ..
  25. ncbi Correcting haemoglobin cut-offs to define anaemia in high-altitude pregnant women in Peru reduces adverse perinatal outcomes
    Gustavo F Gonzales
    Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Honorio Delgado 430, Lima 31, Peru
    Arch Gynecol Obstet 290:65-74. 2014
    ..To determine if correction of cut-offs of haemoglobin levels to define anaemia at high altitudes affects rates of adverse perinatal outcomes...