Mary F Lopez

Summary

Affiliation: PerkinElmer Life and Analytical Sciences

Publications

  1. ncbi A novel, high-throughput workflow for discovery and identification of serum carrier protein-bound peptide biomarker candidates in ovarian cancer samples
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Wellesley, MA 02481 4008, USA
    Clin Chem 53:1067-74. 2007
  2. ncbi High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, MA 02118, USA
    Clin Chem 51:1946-54. 2005
  3. ncbi High-content proteomics: fluorescence multiplexing using an integrated, high-sensitivity, multiwavelength charge-coupled device imaging system
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, 549 Albany Street, Boston, MA 02118, USA
    Proteomics 3:1109-16. 2003
  4. ncbi Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, MA 02118, USA
    Electrophoresis 25:2557-63. 2004
  5. ncbi Proteomic analysis of mitochondrial proteins
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, Massachusetts 02118, USA
    Int Rev Neurobiol 61:31-48. 2004
  6. pmc Proteomic analysis of synovial fluid from the osteoarthritic knee: comparison with transcriptome analyses of joint tissues
    Susan Y Ritter
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:981-92. 2013
  7. ncbi Performance validation of an improved Xenon-arc lamp-based CCD camera system for multispectral imaging in proteomics
    Elaine Scrivener
    PerkinElmer Life and Analytical Sciences, Seer Green, UK
    Proteomics 5:4354-66. 2005
  8. ncbi A robust biomarker discovery pipeline for high-performance mass spectrometry data
    Wayne G Fisher
    Division of Translational Research, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Bioinform Comput Biol 5:1023-45. 2007
  9. ncbi Proteomic patterns for classification of ovarian cancer and CTCL serum samples utilizing peak pairs indicative of post-translational modifications
    Chenwei Liu
    Clinical Proteomics Reference Laboratory, Gaithersburg, MD, USA
    Proteomics 7:4045-52. 2007
  10. ncbi SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness
    Jeffrey S Friedman
    The Scripps Research Institute, Department of Molecular and Experimental Medicine, MEM131, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
    Blood 104:2565-73. 2004

Collaborators

Detail Information

Publications13

  1. ncbi A novel, high-throughput workflow for discovery and identification of serum carrier protein-bound peptide biomarker candidates in ovarian cancer samples
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Wellesley, MA 02481 4008, USA
    Clin Chem 53:1067-74. 2007
    ..To use mass spectrometry (MS) of serum proteins for early detection, a seamless workflow is needed that provides an opportunity for rapid profiling along with direct identification of the underpinning ions...
  2. ncbi High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, MA 02118, USA
    Clin Chem 51:1946-54. 2005
    ....
  3. ncbi High-content proteomics: fluorescence multiplexing using an integrated, high-sensitivity, multiwavelength charge-coupled device imaging system
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, 549 Albany Street, Boston, MA 02118, USA
    Proteomics 3:1109-16. 2003
    ..The ProXPRESS maximizes the efficiency of experimental strategies that require flexibility and multicolor fluorescence detection...
  4. ncbi Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, MA 02118, USA
    Electrophoresis 25:2557-63. 2004
    ....
  5. ncbi Proteomic analysis of mitochondrial proteins
    Mary F Lopez
    PerkinElmer Life and Analytical Sciences, Boston, Massachusetts 02118, USA
    Int Rev Neurobiol 61:31-48. 2004
  6. pmc Proteomic analysis of synovial fluid from the osteoarthritic knee: comparison with transcriptome analyses of joint tissues
    Susan Y Ritter
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:981-92. 2013
    ..We undertook this study to perform a proteomic analysis of knee SF from OA patients and control subjects and to compare the results to microarray expression data from cartilage and synovium...
  7. ncbi Performance validation of an improved Xenon-arc lamp-based CCD camera system for multispectral imaging in proteomics
    Elaine Scrivener
    PerkinElmer Life and Analytical Sciences, Seer Green, UK
    Proteomics 5:4354-66. 2005
    ..The instrument is unique in its capabilities of scanning large areas at high resolution and providing accurate selectable illumination over the UV/visible spectral range, thus maximizing the efficiency of dye multiplexing protocols...
  8. ncbi A robust biomarker discovery pipeline for high-performance mass spectrometry data
    Wayne G Fisher
    Division of Translational Research, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Bioinform Comput Biol 5:1023-45. 2007
    ..While the generalizability of these markers is currently unknown, we have demonstrated the ability of our analytical package to extract biomarker candidates from high-performance mass spectral data...
  9. ncbi Proteomic patterns for classification of ovarian cancer and CTCL serum samples utilizing peak pairs indicative of post-translational modifications
    Chenwei Liu
    Clinical Proteomics Reference Laboratory, Gaithersburg, MD, USA
    Proteomics 7:4045-52. 2007
    ..This simple peak picking technique could be used to guide identification of important peak pairs involved in the disease process...
  10. ncbi SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness
    Jeffrey S Friedman
    The Scripps Research Institute, Department of Molecular and Experimental Medicine, MEM131, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
    Blood 104:2565-73. 2004
    ....
  11. ncbi Protein micro- and macroarrays: digitizing the proteome
    Mary F Lopez
    Proteome Systems, 14 Gill St, Woburn, MA 01801, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 787:19-27. 2003
    ..The rapid growth of proteomics and the active climate for new technology is driving a new generation of companies and academic efforts that are developing novel protein microarray techniques for the future...
  12. ncbi An improved formulation of SYPRO Ruby protein gel stain: comparison with the original formulation and with a ruthenium II tris (bathophenanthroline disulfonate) formulation
    Kiera N Berggren
    Proteomics Section, Molecular Probes, Inc, Eugene, OR 97402, USA
    Proteomics 2:486-98. 2002
    ..An additional benefit of the improved formulation is that it permits staining of proteins in isoelectric focusing gels, without the requirement for caustic acids...
  13. ncbi Applied proteomics: mitochondrial proteins and effect on function
    Mary F Lopez
    Proteome Systems, Woburn, MA 01801, USA
    Circ Res 90:380-9. 2002
    ..Future efforts will focus on linking genomic array information to actual protein levels in mitochondria...