L F Pemberton

Summary

Publications

  1. pmc Nuclear import of the TATA-binding protein: mediation by the karyopherin Kap114p and a possible mechanism for intranuclear targeting
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 145:1407-17. 1999
  2. pmc A nuclear import pathway for a protein involved in tRNA maturation
    J S Rosenblum
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 139:1655-61. 1997
  3. pmc A novel nuclear import pathway for the transcription factor TFIIS
    M Albertini
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    J Cell Biol 143:1447-55. 1998
  4. pmc Nuclear import and the evolution of a multifunctional RNA-binding protein
    J S Rosenblum
    Laboratory of Cell Biology, Howard Hughes Medical Institute and Rockefeller University, New York, New York 10021, USA
    J Cell Biol 143:887-99. 1998
  5. pmc A distinct and parallel pathway for the nuclear import of an mRNA-binding protein
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 139:1645-53. 1997
  6. pmc Characterization of the Wtm proteins, a novel family of Saccharomyces cerevisiae transcriptional modulators with roles in meiotic regulation and silencing
    L F Pemberton
    Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    Mol Cell Biol 17:4830-41. 1997
  7. ncbi request reprint Transport routes through the nuclear pore complex
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021, USA
    Curr Opin Cell Biol 10:392-9. 1998
  8. pmc Disruption of the nucleoporin gene NUP133 results in clustering of nuclear pore complexes
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021
    Proc Natl Acad Sci U S A 92:1187-91. 1995
  9. pmc Nuclear import of histone H2A and H2B is mediated by a network of karyopherins
    N Mosammaparast
    Center for Cell Signaling, Department of Microbiology, Health Sciences Center, University of Virginia, 22908, USA
    J Cell Biol 153:251-62. 2001

Collaborators

Detail Information

Publications9

  1. pmc Nuclear import of the TATA-binding protein: mediation by the karyopherin Kap114p and a possible mechanism for intranuclear targeting
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 145:1407-17. 1999
    ..This suggests a mechanism where, once in the nucleus, TBP is preferentially released from Kap114p at the promoter of genes to be transcribed. In this fashion Kap114p may play a role in the intranuclear targeting of TBP...
  2. pmc A nuclear import pathway for a protein involved in tRNA maturation
    J S Rosenblum
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 139:1655-61. 1997
    ..In addition, through its association with ribosomal proteins, Sxm1p may have a role in coordinating ribosome biogenesis with tRNA processing...
  3. pmc A novel nuclear import pathway for the transcription factor TFIIS
    M Albertini
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    J Cell Biol 143:1447-55. 1998
    ..Hence Kap119p is a novel karyopherin that is responsible for the import of the transcription elongation factor TFIIS...
  4. pmc Nuclear import and the evolution of a multifunctional RNA-binding protein
    J S Rosenblum
    Laboratory of Cell Biology, Howard Hughes Medical Institute and Rockefeller University, New York, New York 10021, USA
    J Cell Biol 143:887-99. 1998
    ..As such, the yeast and human La proteins are imported using different sequence motifs and dissimilar karyopherins. Our results are consistent with an intermingling of the nuclear import and evolution of La...
  5. pmc A distinct and parallel pathway for the nuclear import of an mRNA-binding protein
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York 10021, USA
    J Cell Biol 139:1645-53. 1997
    ..Thus, at least two parallel pathways function in the import of mRNA-binding proteins, suggesting the need for the coordination of these pathways...
  6. pmc Characterization of the Wtm proteins, a novel family of Saccharomyces cerevisiae transcriptional modulators with roles in meiotic regulation and silencing
    L F Pemberton
    Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    Mol Cell Biol 17:4830-41. 1997
    ..These data suggested that Wtm1p and Wtm2p are repressors and that Wtm3p has different effects on transcription at different loci...
  7. ncbi request reprint Transport routes through the nuclear pore complex
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021, USA
    Curr Opin Cell Biol 10:392-9. 1998
    ..However, the mechanisms of transport, particularly the role of Ran, remain poorly understood...
  8. pmc Disruption of the nucleoporin gene NUP133 results in clustering of nuclear pore complexes
    L F Pemberton
    Laboratory of Cell Biology, Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021
    Proc Natl Acad Sci U S A 92:1187-91. 1995
    ..We speculate that the gene product of NUP133, Nup133p, may functionally overlap with the NUP145 gene product, Nup145p, and that these proteins may be involved in maintaining the position of the NPC within the nuclear envelope...
  9. pmc Nuclear import of histone H2A and H2B is mediated by a network of karyopherins
    N Mosammaparast
    Center for Cell Signaling, Department of Microbiology, Health Sciences Center, University of Virginia, 22908, USA
    J Cell Biol 153:251-62. 2001
    ..These data suggest that the import of H2A and H2B is mediated by a network of Kaps, in which Kap114p may play the major role...