M T Pellecchia

Summary

Publications

  1. ncbi request reprint The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurology 64:1810-2. 2005
  2. doi request reprint Observational study of sleep-related disorders in Italian patients with Parkinson's disease: usefulness of the Italian version of Parkinson's disease sleep scale
    M T Pellecchia
    Department of Neurological Sciences, University of Naples, Federico II, Naples, Italy
    Neurol Sci 33:689-94. 2012
  3. ncbi request reprint Parkinsonism and essential tremor in a family with pseudo-dominant inheritance of PARK2: an FP-CIT SPECT study
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University Federico II, Napoli, Italy
    Mov Disord 22:559-63. 2007
  4. pmc Growth hormone stimulation tests in the differential diagnosis of Parkinson's disease
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy
    Clin Med Res 4:322-5. 2006
  5. ncbi request reprint Stimulation of growth hormone release in multiple system atrophy, Parkinson's disease and idiopathic cerebellar ataxia
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurol Sci 22:79-80. 2001
  6. ncbi request reprint Imaging of dopaminergic dysfunction with [123I]FP-CIT SPECT in early-onset parkin disease
    A Varrone
    Biostructure and Bioimaging Institute, National Research Council, Via S Pansini, 5, 80131, Napoli, Italy
    Neurology 63:2097-103. 2004
  7. doi request reprint Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism
    Sabina Pappata
    Institute of Biostructure and Bioimaging, CNR, Naples, Italy
    Neurology 77:1357-62. 2011
  8. ncbi request reprint Excitatory and inhibitory mechanisms in Wilson's disease: investigation with magnetic motor cortex stimulation
    A Perretti
    Department of Neurological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, Italy
    J Neurol Sci 192:35-40. 2001
  9. ncbi request reprint Unawareness of dyskinesias in Parkinson's and Huntington's diseases
    C Vitale
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurol Sci 22:105-6. 2001
  10. ncbi request reprint Adult-onset familial laryngeal abductor paralysis, cerebellar ataxia, and pure motor neuropathy
    F Barbieri
    Department of Neurological Sciences, Federico II University, Naples, Italy
    Neurology 56:1412-4. 2001

Collaborators

Detail Information

Publications26

  1. ncbi request reprint The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurology 64:1810-2. 2005
    ..Only nine patients could be classified as classic or atypical PKAN, and intermediate phenotypes are described. Two patients presented with motor tics and obsessive-compulsive behavior suggestive of Tourette syndrome...
  2. doi request reprint Observational study of sleep-related disorders in Italian patients with Parkinson's disease: usefulness of the Italian version of Parkinson's disease sleep scale
    M T Pellecchia
    Department of Neurological Sciences, University of Naples, Federico II, Naples, Italy
    Neurol Sci 33:689-94. 2012
    ..Daytime sleepiness, depressive symptoms and disease severity correlate with sleep disturbances in Italian PD patients. The PDSS is a valid and reliable tool to evaluate sleep disturbances in Italian patients...
  3. ncbi request reprint Parkinsonism and essential tremor in a family with pseudo-dominant inheritance of PARK2: an FP-CIT SPECT study
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University Federico II, Napoli, Italy
    Mov Disord 22:559-63. 2007
    ..In 3 homozygotes and 1 heterozygote, a 2-year follow-up single photon emission computed tomography suggested no progression of nigrostriatal deficit...
  4. pmc Growth hormone stimulation tests in the differential diagnosis of Parkinson's disease
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University Federico II, Via Pansini 5, 80131 Naples, Italy
    Clin Med Res 4:322-5. 2006
    ..This review summarizes the results of several studies and discusses the validity of these tests in the differential diagnosis of parkinsonisms...
  5. ncbi request reprint Stimulation of growth hormone release in multiple system atrophy, Parkinson's disease and idiopathic cerebellar ataxia
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurol Sci 22:79-80. 2001
    ..We suggest that stimulation of GH release with GHRH-Arg rather than clonidine could differentiate MSA from IPD and ILOCA, but this hypothesis would need to be confirmed by further investigations...
  6. ncbi request reprint Imaging of dopaminergic dysfunction with [123I]FP-CIT SPECT in early-onset parkin disease
    A Varrone
    Biostructure and Bioimaging Institute, National Research Council, Via S Pansini, 5, 80131, Napoli, Italy
    Neurology 63:2097-103. 2004
    ..To investigate whether the presence of parkin gene mutations is associated with different nigrostriatal impairment than other early-onset parkinsonism...
  7. doi request reprint Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism
    Sabina Pappata
    Institute of Biostructure and Bioimaging, CNR, Naples, Italy
    Neurology 77:1357-62. 2011
    ..To characterize brain metabolic changes associated with mild cognitive impairment (MCI) in drug-naive patients with Parkinson disease (PD) using (18)F-fluorodeoxyglucose (FDG) and PET (FDG-PET)...
  8. ncbi request reprint Excitatory and inhibitory mechanisms in Wilson's disease: investigation with magnetic motor cortex stimulation
    A Perretti
    Department of Neurological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, Italy
    J Neurol Sci 192:35-40. 2001
    ..The CSP threshold was increased in seven patients, and CSP was absent in one. These results suggest an intracortical presynaptic motor dysfunction in WD...
  9. ncbi request reprint Unawareness of dyskinesias in Parkinson's and Huntington's diseases
    C Vitale
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurol Sci 22:105-6. 2001
    ..In PD the unawareness seems to be inversely related with severity of dyskinesias, while in HD it is directly related to disease duration and severity...
  10. ncbi request reprint Adult-onset familial laryngeal abductor paralysis, cerebellar ataxia, and pure motor neuropathy
    F Barbieri
    Department of Neurological Sciences, Federico II University, Naples, Italy
    Neurology 56:1412-4. 2001
    ..Neurophysiologic studies showed a pure motor neuropathy. The combined findings and the molecular analysis suggest a new familial disorder. Inheritance is most likely autosomal recessive, but X-linked transmission is also possible...
  11. doi request reprint The GH-IGF system in amyotrophic lateral sclerosis: correlations between pituitary GH secretion capacity, insulin-like growth factors and clinical features
    M T Pellecchia
    Department of Neurological Sciences and Molecular, Federico II University, Naples, Italy
    Eur J Neurol 17:666-71. 2010
    ..Our aim was to investigate the GH-IGF axis in patients with ALS and evaluate correlations between this endocrine system and clinical features...
  12. ncbi request reprint Physical therapy in Parkinson's disease: an open long-term rehabilitation trial
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Ed 17, Via Pansini 5, 80131, Naples, Italy
    J Neurol 251:595-8. 2004
    ..At 3-month follow-up clinical improvements were largely maintained. A sustained improvement of motor skills in PD patients can be achieved with a long-term comprehensive rehabilitation program...
  13. ncbi request reprint Possible gluten sensitivity in multiple system atrophy
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurology 59:1114-5. 2002
  14. ncbi request reprint Clinical presentation and treatment of Wilson's disease: a single-centre experience
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Eur Neurol 50:48-52. 2003
    ..Our results suggest that D-penicillamine or a combination of D-penicillamine and zinc sulphate is a safe and effective long-term treatment in patients with WD...
  15. ncbi request reprint Pure unilateral hyperhidrosis after pontine infarct
    M T Pellecchia
    Department of Neurological Sciences, University Federico II, Naples, Italy
    Neurology 61:1305. 2003
  16. ncbi request reprint The arginine growth hormone stimulation test in bradykinetic-rigid parkinsonisms
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University of Naples Federico II, Naples, Italy
    Mov Disord 23:190-4. 2008
    ..Our results suggest that the impairment of the central mechanisms modulating GH release differs between PSP and MSA-P...
  17. ncbi request reprint Multiple system atrophy is distinguished from idiopathic Parkinson's disease by the arginine growth hormone stimulation test
    Maria Teresa Pellecchia
    Department of Neurological Sciences, University of Naples Federico II, Naples, Italy
    Ann Neurol 60:611-5. 2006
    ..Our aim was to evaluate the accuracy of the arginine growth hormone (GH) stimulation test in distinguishing between MSA and PD in large populations of patients...
  18. ncbi request reprint Reduced striatal [123 I]FP-CIT binding in SCA2 patients without parkinsonism
    Andrea Varrone
    Biostructure and Bioimaging Institute, National Research Council, Via S Pansini 5, 80131 Naples, Italy
    Ann Neurol 55:426-30. 2004
    ..Striatal DAT density of SCA2 patients correlated with the severity of cerebellar ataxia...
  19. ncbi request reprint Growth hormone response to arginine test distinguishes multiple system atrophy from Parkinson's disease and idiopathic late-onset cerebellar ataxia
    Maria Teresa Pellecchia
    Department of Neurological Sciences, Federico II University, 80131 Naples, Italy
    Clin Endocrinol (Oxf) 62:428-33. 2005
    ..This study aimed to evaluate GH response to three different GH stimulation tests in order to establish a reliable test to differentiate these degenerative disorders...
  20. doi request reprint Red flags for multiple system atrophy
    Martin Köllensperger
    Section for Clinical Neurobiology, Department of Neurology, Innsbruck Medical University, Austria
    Mov Disord 23:1093-9. 2008
    ..9 (+/-7.0) months earlier than with the Consensus criteria alone. We propose a combination of two out of six red flag categories as additional diagnostic criteria for probable MSA-P...
  21. ncbi request reprint Paradoxical response to apomorphine in a case of atypical parkinsonism
    Giulio Cicarelli
    Department of Neurological Sciences, Universita Federico II, Napoli, Italy
    Mov Disord 17:604-6. 2002
    ..We discuss possible pathogenetic mechanisms with regard to the literature and suggest the diagnosis of a striatonigral degeneration at an early stage...
  22. ncbi request reprint Hallervorden-Spatz syndrome resembling a typical Tourette syndrome
    Valentina Scarano
    Department of Neurological Sciences, Universita Federico II, Napoli, Italy
    Mov Disord 17:618-20. 2002
    ..It is recommended that, even in the case of slow progression, HSS should be considered in the differential diagnosis of TS-like disorders...
  23. doi request reprint PINK1 heterozygous rare variants: prevalence, significance and phenotypic spectrum
    Roberta Marongiu
    IRCCS CSS Mendel Institute, Rome, Italy
    Hum Mutat 29:565. 2008
    ..Hence, their significance should be kept distinct from that of homozygous/compound heterozygous mutations, that cause parkinsonism inherited in a mendelian fashion...
  24. ncbi request reprint Frontal dysfunction contributes to the genesis of hallucinations in non-demented Parkinsonian patients
    Dario Grossi
    Department of Psychology, Second University, Naples, Italy
    Int J Geriatr Psychiatry 20:668-73. 2005
    ..Hallucinations are significantly associated with dementia in PD, but little is known about possible distinctive cognitive features of non-demented PD patients who develop hallucinations...
  25. ncbi request reprint Twenty-four novel mutations in Wilson disease patients of predominantly Italian origin
    Maria Barbara Lepori
    Dipartimento di Scienze Biomediche e Biotecnologie, USC, Cagliari, Italy
    Genet Test 11:328-32. 2007
    ..Detection of new mutations in the ATP7B gene increases our capability of molecular analysis that is essential for early diagnosis and treatment of WD...
  26. ncbi request reprint Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians
    Daniele Ghezzi
    Unit of Molecular Neurogenetics, National Neurological Institute, Carlo Besta, Milan, Italy
    Eur J Hum Genet 13:748-52. 2005
    ..Our study suggests that haplogroup K might confer a lower risk for PD in Italians, corroborating the idea that the mitochondrial oxidative phosphorylation pathway is involved in the susceptibility to idiopathic PD...