Katherine A Peebles

Summary

Publications

  1. pmc Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer
    Felicita Baratelli
    UCLA Lung Cancer Research Program of the Jonsson Comprehensive Cancer Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Los Angeles, CA 90095, USA
    J Transl Med 6:38. 2008
  2. ncbi request reprint Inflammation and lung carcinogenesis: applying findings in prevention and treatment
    Katherine A Peebles
    David Geffen School of Medicine at UCLA, Division of Pulmonary and Critical Care Medicine and Hospitalists, Department of Medicine, UCLA Lung Cancer Research Program, CA, USA
    Expert Rev Anticancer Ther 7:1405-21. 2007
  3. pmc Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment
    Jay M Lee
    Division of Cardiothoracic Surgery, Department of Surgery, UCLA Lung Cancer Research Program, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Crit Rev Oncol Hematol 66:208-17. 2008
  4. pmc The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer
    Saswati Hazra
    UCLA Lung Cancer Research Program, Division of Pulmonary and Critical Care Medicine and Hospitalists, Department of Medicine, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    PPAR Res 2008:790568. 2008
  5. ncbi request reprint Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1
    Katherine A Peebles
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver 80262, USA
    Carcinogenesis 24:651-7. 2003
  6. ncbi request reprint Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia
    Katherine A Peebles
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, Denver, Colorado 80215, USA
    Mol Carcinog 46:887-900. 2007
  7. pmc EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells
    Ming Liu
    Lung Cancer Research Program, Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California 90095, USA
    Am J Respir Cell Mol Biol 37:578-88. 2007

Collaborators

Detail Information

Publications7

  1. pmc Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer
    Felicita Baratelli
    UCLA Lung Cancer Research Program of the Jonsson Comprehensive Cancer Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Los Angeles, CA 90095, USA
    J Transl Med 6:38. 2008
    ..These results have provided the rationale to generate a clinical grade adenoviral vector encoding CCL-21 for ex vivo transduction of human DC in order to assess intratumoral administration in late stage human lung cancer...
  2. ncbi request reprint Inflammation and lung carcinogenesis: applying findings in prevention and treatment
    Katherine A Peebles
    David Geffen School of Medicine at UCLA, Division of Pulmonary and Critical Care Medicine and Hospitalists, Department of Medicine, UCLA Lung Cancer Research Program, CA, USA
    Expert Rev Anticancer Ther 7:1405-21. 2007
    ..These newly discovered molecular mechanisms in the pathogenesis of lung cancer provide novel opportunities for targeted therapy and prevention in lung cancer...
  3. pmc Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment
    Jay M Lee
    Division of Cardiothoracic Surgery, Department of Surgery, UCLA Lung Cancer Research Program, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Crit Rev Oncol Hematol 66:208-17. 2008
    ..The understanding of molecular mechanisms involved in inflammation and lung carcinogenesis provide insight for new drug development that target reversible, non-mutational events in the chemoprevention and treatment of lung cancer...
  4. pmc The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer
    Saswati Hazra
    UCLA Lung Cancer Research Program, Division of Pulmonary and Critical Care Medicine and Hospitalists, Department of Medicine, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    PPAR Res 2008:790568. 2008
    ..Understanding the mechanisms underlying these effects may be helpful for designing anticancer therapies. This article summarizes recent research on the relationship between (PPARgamma), TZDs, and the COX-2/PGE2 pathways in lung cancer...
  5. ncbi request reprint Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1
    Katherine A Peebles
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver 80262, USA
    Carcinogenesis 24:651-7. 2003
    ..The PDI superfamily has multiple cellular roles including chaperoning assembled glycoproteins, regulating the activities of transcription factors, and regulating disulfide bond formation...
  6. ncbi request reprint Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia
    Katherine A Peebles
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, Denver, Colorado 80215, USA
    Mol Carcinog 46:887-900. 2007
    ....
  7. pmc EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells
    Ming Liu
    Lung Cancer Research Program, Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California 90095, USA
    Am J Respir Cell Mol Biol 37:578-88. 2007
    ..These findings emphasize the central role of EGFR signaling in COX-2 induction by TGF-beta1 and suggest that inhibition of EGFR signaling should be investigated further for lung cancer prevention...