T Pederson

Summary

Publications

  1. pmc The plurifunctional nucleolus
    T Pederson
    Worcester Foundation for Biomedical Research and Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester Foundation Campus, 222 Maple Avenue, Shrewsbury, MA 01545, USA
    Nucleic Acids Res 26:3871-6. 1998
  2. ncbi request reprint Thinking about a nuclear matrix
    T Pederson
    Worcester Foundation for Biomedical Research, Shrewsbury, MA 01545, USA
    J Mol Biol 277:147-59. 1998
  3. pmc Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs
    S H Mayrand
    Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Nucleic Acids Res 18:3307-18. 1990
  4. ncbi request reprint Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites
    S V Yarovoi
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, MA 01605, USA
    Gene 275:73-81. 2001
  5. pmc Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells
    J C Politz
    Worcester Foundation for Biomedical Research, University of Massachusetts Medical Center, Worcester Foundation Campus, Shrewsbury, MA 01545, USA
    Proc Natl Acad Sci U S A 95:6043-8. 1998
  6. ncbi request reprint Evidence for an association between U1 RNA and interspersed repeat single-copy RNAs in the cytoplasm of sea urchin eggs
    S Ruzdijic
    Cell Bilogy Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Development 101:107-16. 1987
  7. ncbi request reprint Movement and localization of RNA in the cell nucleus
    T Pederson
    Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01605, USA
    FASEB J 13:S238-42. 1999
  8. pmc Half a century of "the nuclear matrix"
    T Pederson
    Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    Mol Biol Cell 11:799-805. 2000
  9. ncbi request reprint Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells
    J C Politz
    Department of Biochemistry and Molecular Biology, Biomedical Imaging Center, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    Curr Biol 9:285-91. 1999
  10. pmc The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins
    J R Patton
    Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Proc Natl Acad Sci U S A 85:747-51. 1988

Collaborators

Detail Information

Publications13

  1. pmc The plurifunctional nucleolus
    T Pederson
    Worcester Foundation for Biomedical Research and Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester Foundation Campus, 222 Maple Avenue, Shrewsbury, MA 01545, USA
    Nucleic Acids Res 26:3871-6. 1998
    ..The plurifunctional nucleolus concept has a strong footing in contemporary data and adds a new perspective to our current picture of the spatial-functional design of the cell nucleus...
  2. ncbi request reprint Thinking about a nuclear matrix
    T Pederson
    Worcester Foundation for Biomedical Research, Shrewsbury, MA 01545, USA
    J Mol Biol 277:147-59. 1998
    ..Important new clues are now coming in from promising contemporary lines of research that report on nuclear structure in living cells...
  3. pmc Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs
    S H Mayrand
    Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Nucleic Acids Res 18:3307-18. 1990
    ....
  4. ncbi request reprint Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites
    S V Yarovoi
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, MA 01605, USA
    Gene 275:73-81. 2001
    ..Both of these observed intranuclear localizations have relevance to the potential applications of this system...
  5. pmc Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells
    J C Politz
    Worcester Foundation for Biomedical Research, University of Massachusetts Medical Center, Worcester Foundation Campus, Shrewsbury, MA 01545, USA
    Proc Natl Acad Sci U S A 95:6043-8. 1998
    ..These results demonstrate that oligos can move about within the nucleus at rates comparable to those in aqueous solution and further suggest that this is true for large ribonucleoprotein complexes as well...
  6. ncbi request reprint Evidence for an association between U1 RNA and interspersed repeat single-copy RNAs in the cytoplasm of sea urchin eggs
    S Ruzdijic
    Cell Bilogy Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Development 101:107-16. 1987
    ..These results raise the possibility that maternal interspersed RNAs include unprocessed pre-messenger RNA molecules in arrested complexes with splicing cofactors...
  7. ncbi request reprint Movement and localization of RNA in the cell nucleus
    T Pederson
    Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01605, USA
    FASEB J 13:S238-42. 1999
    ..The methods we have developed and these initial results represent the first major step toward a comprehensive understanding of RNA traffic in the cell nucleus...
  8. pmc Half a century of "the nuclear matrix"
    T Pederson
    Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    Mol Biol Cell 11:799-805. 2000
    ....
  9. ncbi request reprint Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells
    J C Politz
    Department of Biochemistry and Molecular Biology, Biomedical Imaging Center, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    Curr Biol 9:285-91. 1999
    ....
  10. pmc The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins
    J R Patton
    Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Proc Natl Acad Sci U S A 85:747-51. 1988
    ....
  11. pmc Fluorescent RNA cytochemistry: tracking gene transcripts in living cells
    T Pederson
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 377 Plantation Street, Worcester, MA 01605, USA
    Nucleic Acids Res 29:1013-6. 2001
    ....
  12. pmc Signal recognition particle components in the nucleolus
    J C Politz
    Department of Biochemistry, University of Massachusetts Medical School, 377 Plantation Street, Suite 337, Worcester, MA 01605, USA
    Proc Natl Acad Sci U S A 97:55-60. 2000
    ..Our findings support the notion that the nucleolus is the site of assembly and/or interaction between the family of ribonucleoproteins involved in protein synthesis, in addition to ribosomes themselves...
  13. pmc Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA
    S H Mayrand
    Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545
    Proc Natl Acad Sci U S A 90:7764-8. 1993
    ..These results indicate that the participation of C hnRNP proteins in pre-spliceosome assembly is coupled to a dynamic cycle of their phosphorylation and dephosphorylation...