Jodi L Pawluski

Summary

Publications

  1. doi Chronic fluoxetine treatment and maternal adversity differentially alter neurobehavioral outcomes in the rat dam
    Jodi L Pawluski
    School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Behav Brain Res 228:159-68. 2012
  2. doi Effects of stress early in gestation on hippocampal neurogenesis and glucocorticoid receptor density in pregnant rats
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, The Netherlands University of Liege, GIGA Neurosciences, 1 Avenue de l Hôpital Bat B36, B 4000 Liege, Belgium Department of Biological Sciences, Ohio University, Athens, OH, USA Electronic address
    Neuroscience 290:379-88. 2015
  3. doi Pregnancy or stress decrease complexity of CA3 pyramidal neurons in the hippocampus of adult female rats
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, The Netherlands
    Neuroscience 227:201-10. 2012
  4. doi Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Neuroscience 220:131-41. 2012
  5. doi Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function
    Jodi L Pawluski
    Early Human Experience Unit, Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    Psychoneuroendocrinology 37:1019-28. 2012
  6. doi Stress and the pregnant female: Impact on hippocampal cell proliferation, but not affective-like behaviors
    Jodi L Pawluski
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Horm Behav 59:572-80. 2011
  7. pmc Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence
    Ine Rayen
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e24003. 2011
  8. doi Reproductive experience alters corticosterone and CBG levels in the rat dam
    Jodi L Pawluski
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
    Physiol Behav 96:108-14. 2009
  9. doi Developmental fluoxetine exposure facilitates sexual behavior in female offspring
    Ine Rayen
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Psychopharmacology (Berl) 231:123-33. 2014
  10. ncbi Maternal care affects male and female offspring working memory and stress reactivity
    Cindy K Barha
    Department of Psychology and Brain Research Centre, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Physiol Behav 92:939-50. 2007

Collaborators

Detail Information

Publications27

  1. doi Chronic fluoxetine treatment and maternal adversity differentially alter neurobehavioral outcomes in the rat dam
    Jodi L Pawluski
    School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Behav Brain Res 228:159-68. 2012
    ....
  2. doi Effects of stress early in gestation on hippocampal neurogenesis and glucocorticoid receptor density in pregnant rats
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, The Netherlands University of Liege, GIGA Neurosciences, 1 Avenue de l Hôpital Bat B36, B 4000 Liege, Belgium Department of Biological Sciences, Ohio University, Athens, OH, USA Electronic address
    Neuroscience 290:379-88. 2015
    ..01). This work adds to our understanding of how stress and reproductive state affect plasticity in the female hippocampus. ..
  3. doi Pregnancy or stress decrease complexity of CA3 pyramidal neurons in the hippocampus of adult female rats
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6200 MD Maastricht, The Netherlands
    Neuroscience 227:201-10. 2012
    ..This work shows that both repeated restraint stress and pregnancy affect dendritic morphology by decreasing complexity of CA3, but not CA1, neurons in the hippocampus...
  4. doi Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring
    J L Pawluski
    School for Mental Health and Neuroscience, Department of Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Neuroscience 220:131-41. 2012
    ..Together, these results highlight a marked sex difference in the long-term effect of developmental exposure to SSRI medications that may differentially alter the capacity of the hippocampus to respond to stress...
  5. doi Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function
    Jodi L Pawluski
    Early Human Experience Unit, Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    Psychoneuroendocrinology 37:1019-28. 2012
    ..To address this, prenatal exposure to SSRIs and maternal mood were examined in relation to neonatal and infant levels of cortisol and its binding protein, corticosteroid-binding globulin (CBG)...
  6. doi Stress and the pregnant female: Impact on hippocampal cell proliferation, but not affective-like behaviors
    Jodi L Pawluski
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Horm Behav 59:572-80. 2011
    ..Understanding how stress affects the female during different reproductive states will aid in improving the health and well being of the mother and child...
  7. pmc Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence
    Ine Rayen
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e24003. 2011
    ..This research provides important evidence on the long-term effect of fluoxetine exposure during development in a model of maternal adversity...
  8. doi Reproductive experience alters corticosterone and CBG levels in the rat dam
    Jodi L Pawluski
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada
    Physiol Behav 96:108-14. 2009
    ....
  9. doi Developmental fluoxetine exposure facilitates sexual behavior in female offspring
    Ine Rayen
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Psychopharmacology (Berl) 231:123-33. 2014
    ....
  10. ncbi Maternal care affects male and female offspring working memory and stress reactivity
    Cindy K Barha
    Department of Psychology and Brain Research Centre, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Physiol Behav 92:939-50. 2007
    ..Male offspring of low licking/grooming dams showed a flattened corticosterone response to stress. Thus variations in maternal care differentially affect working memory and stress reactivity in male and female offspring...
  11. ncbi First reproductive experience persistently affects spatial reference and working memory in the mother and these effects are not due to pregnancy or 'mothering' alone
    Jodi L Pawluski
    Program in Neuroscience, Department of Psychology and Brain Research Center, University of British Columbia, 2136 West Mall, Vancouver, BC, V6T 1Z4 Canada
    Behav Brain Res 175:157-65. 2006
    ..Clearly the combination of first pregnancy and first mothering experience has a significant impact on hippocampus-dependent learning and memory performance in the mother...
  12. doi Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring
    Ine Rayen
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Psychoneuroendocrinology 38:1618-29. 2013
    ..These results provide important evidence for the long-term impact of maternal adversity and maternal fluoxetine use on the development of primary endocrinology systems in juvenile and adult male offspring. ..
  13. pmc Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring
    Liesbeth Knaepen
    Department of Anesthesiology Pain Management, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 8:e57608. 2013
    ..Thus, developmental fluoxetine exposure normalizes the long-term effects of maternal adversity on post-operative pain in offspring and these effects may be due, in part, to the involvement of the HPA system...
  14. doi Endocrine regulation of cognition and neuroplasticity: our pursuit to unveil the complex interaction between hormones, the brain, and behaviour
    Liisa A M Galea
    Department of Psychology, Program in Neuroscience, University of British Columbia, Vancouver, Canada
    Can J Exp Psychol 62:247-60. 2008
    ..It is of the upmost importance to investigate the effects on neuroplasticity and behaviour in both the male and the female, particularly when modelling diseases that exhibit sex differences in incidence, etiology or treatment...
  15. ncbi Hippocampal morphology is differentially affected by reproductive experience in the mother
    Jodi L Pawluski
    Program in Neuroscience, Department of Psychology and Brain Research Center, University of British Columbia, 2136 West Mall, Vancouver, BC, V6T 1Z4, Canada
    J Neurobiol 66:71-81. 2006
    ..These findings point to the effect of reproductive experience and offspring on plasticity in the hippocampus, an area not traditionally associated with motherhood...
  16. doi Neonatal S100B protein levels after prenatal exposure to selective serotonin reuptake inhibitors
    Jodi L Pawluski
    Department of Pediatrics, University of British Columbia, Vancouver, Canada
    Pediatrics 124:e662-70. 2009
    ..This study investigated neonatal S100B levels as a biomarker of prenatal selective serotonin reuptake inhibitor (SSRI) exposure...
  17. doi Everyday life memory deficits in pregnant women
    Carrie Cuttler
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Can J Exp Psychol 65:27-37. 2011
    ..The predominant use of laboratory tests may explain the myriad of previous failures to detect objective deficits in pregnant women's memory...
  18. doi Offspring-exposure reduces depressive-like behaviour in the parturient female rat
    Jodi L Pawluski
    Program in Neuroscience, Department of Psychology and Brain Research Center, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Behav Brain Res 197:55-61. 2009
    ..Further research is needed to determine the extent of these changes and the neural and hormonal correlates of these events...
  19. doi Perinatal maternal stress and serotonin signaling: effects on pain sensitivity in offspring
    Liesbeth Knaepen
    Department of Anesthesiology Pain Management, University Pain Center Maastricht, Maastricht University Medical Center, Universiteitssingel 50, 6229 ER Maastricht, Maastricht, The Netherlands School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Dev Psychobiol 56:885-96. 2014
    ..This review sheds light on the effect of perinatal maternal stress and treatment with SSRIs on offspring pain sensitivity, in relation to the developing HPA system and 5-HT signaling...
  20. doi ERalpha, but not ERbeta, mediates the expression of sexual behavior in the female rat
    Christine A Mazzucco
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC V6T 1Z4, Canada
    Behav Brain Res 191:111-7. 2008
    ..5mg dose resulted in reduced levels of proceptivity and receptivity, suggesting that ERbeta modulates ERalpha's ability to elicit receptive and proceptive sexual behavior...
  21. pmc Fluoxetine dose and administration method differentially affect hippocampal plasticity in adult female rats
    Jodi L Pawluski
    GIGA Neurosciences, University of Liege, 1 Avenue de l Hopital, Bâtiment B36, 4000 Liege, Belgium School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, The Netherlands Department of Biological Sciences, Irvine Hall, Ohio University, Athens, OH 45701, USA
    Neural Plast 2014:123026. 2014
    ..These data suggest that the administration method and dose of fluoxetine can differentially affect hippocampal plasticity in the adult female rat...
  22. doi Perinatal selective serotonin reuptake inhibitor exposure: impact on brain development and neural plasticity
    Jodi L Pawluski
    Department of Neuroscience, School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands j pawluski maastrichtuniversity nl
    Neuroendocrinology 95:39-46. 2012
    ..This minireview will highlight emerging evidence from clinical and preclinical studies investigating the impact of perinatal SSRI exposure on brain development and neural plasticity...
  23. ncbi Gonadal hormone modulation of hippocampal neurogenesis in the adult
    Liisa A M Galea
    Program in Neuroscience, Department of Psychology and Brain Research Centre, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada
    Hippocampus 16:225-32. 2006
    ..Clearly, more work needs to be done to elucidate the effects of gonadal hormones on neurogenesis in the DG of both male and female rodents...
  24. doi Altered emotionality, hippocampus-dependent performance and expression of NMDA receptor subunit mRNAs in chronically stressed mice
    João Costa-Nunes
    Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Stress 17:108-16. 2014
    ..Thus, stress-induced aberrations in both hippocampal-dependent performance and emotional abnormalities are associated with alterations in hippocampal mRNA NR2A levels and the NR2A/NR2B ratio and not with mRNA expression of NR2B or NR1...
  25. doi Developmental exposure to SSRIs, in addition to maternal stress, has long-term sex-dependent effects on hippocampal plasticity
    Ine Rayen
    School for Mental Health and Neuroscience, Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands
    Psychopharmacology (Berl) 232:1231-44. 2015
    ....
  26. pmc Long-term corticosterone exposure decreases insulin sensitivity and induces depressive-like behaviour in the C57BL/6NCrl mouse
    Eva L Van Donkelaar
    School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 9:e106960. 2014
    ....
  27. ncbi Reproductive experience differentially affects spatial reference and working memory performance in the mother
    Jodi L Pawluski
    Program in Neuroscience, Department of Psychology and Brain Research Center, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada V6T 1Z4
    Horm Behav 49:143-9. 2006
    ....