The mRNA expression of SATB1 and SATB2 in human breast cancerNeill Patani
Department of Breast Surgery, St, George s University of London, London, UK
Cancer Cell Int 9:18. 2009
..SATB2 mRNA expression is significantly associated with increasing tumour grade and poorer OS. These results are consistent with the notion that SATB1 acts as a 'master genome organizer' in human breast carcinogenesis...
Current management of DCIS: a reviewNeill Patani
The London Breast Institute, The Princess Grace Hospital, 45 Nottingham Place, London, W1U 5NY, UK
Breast Cancer Res Treat 111:1-10. 2008
..This article reviews the management strategies for DCIS in the context of recent randomized trials, including the role of sentinel lymph node biopsy, adjuvant radiotherapy and tamoxifen...
The clinical significance of sentinel lymph node micrometastasis in breast cancerNeill Patani
The London Breast Institute, The Princess Grace Hospital, 45 Nottingham Place, London W1U 5NY, UK
Breast Cancer Res Treat 114:393-402. 2009
..In this article we review the literature concerning axillary lymph node (ALN) MM, with particular reference to SLNB. The controversies regarding histopathological assessment, clinical relevance and management implications are discussed...
- Oncological outcome and patient satisfaction with skin-sparing mastectomy and immediate breast reconstruction: a prospective observational study
Sara Reefy
The London Breast Institute, The Princess Grace Hospital, London, UK
BMC Cancer 10:171. 2010
..In this study, the oncological outcome, post-operative morbidity and patients' satisfaction with SSM and IBR using the latissimus dorsi (LD) myocutaneous flap and/or breast prosthesis is evaluated...
- Clinical significance of sentinel lymph node isolated tumour cells in breast cancer
Neill Patani
The London Breast Institute, The Princess Grace Hospital, London, UK
Breast Cancer Res Treat 127:325-34. 2011
..Evidence supporting the routine analysis of deeper tissue sections by IHC is lacking and molecular technologies should be restricted to research purposes at present...
- Osteopontin expression profiles predict pathological and clinical outcome in breast cancer
Neill Patani
The London Breast Institute, The Princess Grace Hospital, London, UK
Anticancer Res 28:4105-10. 2008
..Osteopontin (OPN) overexpression in breast cancer has been associated with adverse pathological and clinical outcomes. In this study, the OPN expression profiles were examined in a cohort of breast cancer patients...
- Molecular evidence in support of the neoplastic and precursor nature of microglandular adenosis
Felipe C Geyer
Molecular Pathology Team, The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK
Histopathology 60:E115-30. 2012
..The aims of this study were to determine whether MGAs harbour genetic alterations and if any such genetic aberrations found in MGAs are similar to those found in matched invasive carcinomas...
- High TIMM17A expression is associated with adverse pathological and clinical outcomes in human breast cancer
Mohamed Salhab
St George s University of London, UK
Breast Cancer 19:153-60. 2012
..In this study, TIMM17A mRNA expression was evaluated in benign and malignant breast tissues and correlated with pathological and clinical outcomes...
- Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer
Neill Patani
Department of Breast Surgery, The London Breast Institute, The Princess Grace Hospital, London, UK
Anticancer Res 31:4115-25. 2011
....
- Tumour suppressor function of MDA-7/IL-24 in human breast cancer
Neill Patani
Department of Breast Surgery, The London Breast Institute, The Princess Grace Hospital, 42 52 Nottingham Place, W1U 5NY, London, UK
Cancer Cell Int 10:29. 2010
..Furthermore, mRNA expression of MDA-7 is assessed in a cohort of women with BC and correlated with established pathological parameters and clinical outcome...
- Sentinel lymph node micrometastasis in human breast cancer: an update
Mohamed Salhab
London Breast Institute, The Princess Grace Hospital, 45 Nottingham Place, London W1U 5NY, UK
Surg Oncol 20:e195-206. 2011
..The controversies regarding histopathological assessment, clinical relevance and management implications are also discussed...
- High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform
Maryou B K Lambros
Molecular Pathology Team, The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK
Lab Invest 91:1491-501. 2011
..In keeping with other highly sensitive assays, further refinement of this technique is necessary to reduce the number of false-positive results...
- Prognostic utility of glycosyltransferase expression in breast cancer
Neill Patani
The London Breast Institute, The Princess Grace Hospital, London, UK
Cancer Genomics Proteomics 5:333-40. 2008
....
- Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer
Neill Patani
Department of Breast Surgery, The London Breast Institute, The Princess Grace Hospital, London
J Carcinog 9:9. 2010
..However, paradoxical roles are reported. In this study, the level of mRNA expression of CHIP and LOX were assessed in normal and malignant breast tissue and correlated with clinico-pathological parameters...
- Ductal carcinoma in-situ: an update for clinical practice
Neill Patani
The London Breast Institute, The Princess Grace Hospital, London, UK
Surg Oncol 20:e23-31. 2011
..This article reviews current management strategies for DCIS in the context of recent randomized trials, including the role of sentinel lymph node biopsy (SLNB), adjuvant radiotherapy (RT) and endocrine treatment...
- Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer
Neill Patani
Department of Breast Surgery, The London Breast Institute, The Princess Grace Hospital, 42 52 Nottingham Place, W1U 5NY, London, England, UK
Cancer Cell Int 11:23. 2011
..abstract:..
- Direct evidence for concurrent morphological and genetic heterogeneity in an invasive ductal carcinoma of triple-negative phenotype
Neill Patani
The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK
J Clin Pathol 64:822-8. 2011
..The results provide additional direct evidence of intra-tumour genetic heterogeneity in breast cancer and demonstrate that morphologically distinct regions can be associated with distinct genetic aberrations...
- Oncological and aesthetic considerations of skin-sparing mastectomy
Neill Patani
London Breast Institute, The Princess Grace Hospital, London, W1U 5NY, UK
Breast Cancer Res Treat 111:391-403. 2008
..Controversies including the impact of radiotherapy (RT) on immediate breast reconstruction (IBR), preservation of the nipple-areola complex (NAC) and the role of endoscopic mastectomy are also considered...
- Osteopontin C mRNA expression is associated with a poor clinical outcome in human breast cancer
Neill Patani
Int J Cancer 122:2646. 2008
- Changes in breast cancer incidence rates
Neill Patani
Cancer Epidemiol Biomarkers Prev 17:742. 2008
