R Jeroen Pasterkamp

Summary

Publications

  1. ncbi request reprint Semaphorin junction: making tracks toward neural connectivity
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Curr Opin Neurobiol 13:79-89. 2003
  2. pmc Expression patterns of semaphorin7A and plexinC1 during rat neural development suggest roles in axon guidance and neuronal migration
    R Jeroen Pasterkamp
    Solomon H Snyder Department of Neuroscience and Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, 1001 PCTB, 725 North Wolfe Street, Baltimore, MD 21205, USA
    BMC Dev Biol 7:98. 2007
  3. pmc MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function
    Alicia L Degano
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell Neurosci 42:243-54. 2009
  4. ncbi request reprint MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell Neurosci 31:52-69. 2006
  5. ncbi request reprint R-Ras fills another GAP in semaphorin signalling
    R Jeroen Pasterkamp
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Trends Cell Biol 15:61-4. 2005
  6. ncbi request reprint Semaphorin 7A promotes axon outgrowth through integrins and MAPKs
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Nature 424:398-405. 2003
  7. ncbi request reprint MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion
    Jonathan R Terman
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Cell 109:887-900. 2002
  8. ncbi request reprint Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin
    Kazuhiro Suzuki
    Department of Molecular Immunology and CREST Program of JST, Research Institute for Microbial Diseases, Osaka University, 3 1 Yamada oka, Suita, Osaka 565 0871, Japan
    Nature 446:680-4. 2007
  9. ncbi request reprint MICAL flavoprotein monooxygenases: structure, function and role in semaphorin signaling
    Sharon M Kolk
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Adv Exp Med Biol 600:38-51. 2007
  10. ncbi request reprint Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively
    Isabelle Chabbert-de Ponnat
    INSERM U448, Faculty of Medicine, 8 rue du General Sarrail, 94010 Creteil Cedex, France
    Int Immunol 17:439-47. 2005

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Semaphorin junction: making tracks toward neural connectivity
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Curr Opin Neurobiol 13:79-89. 2003
    ..Our understanding of the intracellular signal transduction machinery linking semaphorins to actin dynamics is limited; however, recent advances provide a more comprehensive view of the molecular basis of neuronal semaphorin signaling...
  2. pmc Expression patterns of semaphorin7A and plexinC1 during rat neural development suggest roles in axon guidance and neuronal migration
    R Jeroen Pasterkamp
    Solomon H Snyder Department of Neuroscience and Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, 1001 PCTB, 725 North Wolfe Street, Baltimore, MD 21205, USA
    BMC Dev Biol 7:98. 2007
    ..To gain further insight into the function(s) of Sema7A and plexinC1 during neural development, we present here a detailed analysis of Sema7A and plexinC1 expression in the developing rat nervous system...
  3. pmc MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function
    Alicia L Degano
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell Neurosci 42:243-54. 2009
    ..These findings have broad implications for the role of MECP2 in neurodevelopment and RTT, given the critical role of the semaphorins in the formation of neural circuits...
  4. ncbi request reprint MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell Neurosci 31:52-69. 2006
    ..These results implicate MICALs in neuronal regeneration and support the possibility of employing EGCG to attenuate Sema3-mediated axon repulsion in the injured spinal cord...
  5. ncbi request reprint R-Ras fills another GAP in semaphorin signalling
    R Jeroen Pasterkamp
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Trends Cell Biol 15:61-4. 2005
    ..These results indicate that plexins not only bind to but also regulate directly the activity of some of their downstream effectors...
  6. ncbi request reprint Semaphorin 7A promotes axon outgrowth through integrins and MAPKs
    R Jeroen Pasterkamp
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Nature 424:398-405. 2003
    ....
  7. ncbi request reprint MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion
    Jonathan R Terman
    Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Cell 109:887-900. 2002
    ..These results suggest a novel role for oxidoreductases in repulsive neuronal guidance...
  8. ncbi request reprint Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin
    Kazuhiro Suzuki
    Department of Molecular Immunology and CREST Program of JST, Research Institute for Microbial Diseases, Osaka University, 3 1 Yamada oka, Suita, Osaka 565 0871, Japan
    Nature 446:680-4. 2007
    ..These findings not only identify a function of Sema7A as an effector molecule in T-cell-mediated inflammation, but also reveal a mechanism of integrin-mediated immune regulation...
  9. ncbi request reprint MICAL flavoprotein monooxygenases: structure, function and role in semaphorin signaling
    Sharon M Kolk
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Adv Exp Med Biol 600:38-51. 2007
    ..This review summarizes our current understanding of MICALs, with an emphasis on their role in semaphorin signaling...
  10. ncbi request reprint Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively
    Isabelle Chabbert-de Ponnat
    INSERM U448, Faculty of Medicine, 8 rue du General Sarrail, 94010 Creteil Cedex, France
    Int Immunol 17:439-47. 2005
    ..Together these results suggest that sCD100 plays a critical role in the regulation of antigen-presenting cell migration and functions via a tightly regulated process of receptor expression...
  11. doi request reprint Getting connected in the dopamine system
    Dianne M A Van den Heuvel
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Prog Neurobiol 85:75-93. 2008
    ....
  12. doi request reprint Semaphorin signaling: progress made and promises ahead
    Yeping Zhou
    Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, Utrecht, The Netherlands
    Trends Biochem Sci 33:161-70. 2008
    ..These discoveries could lead to therapeutic advances in axonal regeneration, cancer and other diseases...
  13. pmc Semaphorins in axon regeneration: developmental guidance molecules gone wrong?
    R Jeroen Pasterkamp
    Department of Pharmacology and Anatomy, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Philos Trans R Soc Lond B Biol Sci 361:1499-511. 2006
    ....