Extracorporeal photopheresis affects co-stimulatory molecule expression and interleukin-10 production by dendritic cells in graft-versus-host disease patientsM Di Renzo
Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Italy
Clin Exp Immunol 151:407-13. 2008
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- Enhanced apoptosis of T cells in common variable immunodeficiency (CVID): role of defective CD28 co-stimulation
M Di Renzo
Division of Clinical Immunology, The Mount Sinai Medical Center, New York City, NY, USA
Clin Exp Immunol 120:503-11. 2000
..Defects of the CD28 receptor pathway, leading to cytokine deprivation and dysregulation of bcl-xL, could lead to poor T cell viability and some of the cellular defects observed in CVID...
Inhibition of maturation of human monocyte-derived dendritic cells in a patient with Mycobacterium avium infectionM Di Renzo
Department of Clinical Medicine and Immunological Sciences, Azienda Ospedaliera Universitaria Senese, U O di Medicina III, Policlinico Le Scotte, 53100 Siena, Italy
Int J Immunopathol Pharmacol 19:391-7. 2006
..Inhibition of DC maturation by the in vivo infection with Mycobacterium avium may be an immune-evasion mechanism used by the pathogen because incompletely matured DCs may not activate effector T cells efficiently in vivo...
- Iloprost treatment reduces TNF-alpha production and TNF-RII expression in critical limb ischemia patients without affecting IL6
M Di Renzo
Department of Clinical Medicine and Immunological Sciences, Section of Internal Medicine, Azienda Ospedaliera Universitaria Senese, Siena, Italy
Prostaglandins Leukot Essent Fatty Acids 73:405-10. 2005
..Our data show that iloprost may have anti-inflammatory effects in addition to the well-known vasodilatatory and anti-aggregant ones...
- Extracorporeal photopheresis affects interleukin (IL)-10 and IL-12 production by monocytes in patients with chronic graft-versus-host disease
M Di Renzo
Department of Internal Medicine and Immunology, University of Siena, 53100 Siena, Italy
Br J Dermatol 153:59-65. 2005
..Extracorporeal photopheresis (ECP) has recently been introduced as an alternative treatment for cases of cGVHD refractory to conventional immunosuppressive treatment, but its mechanism of action is not yet clear...
- [Hypogammaglobulinemia and thymoma (Good's syndrome): a case report and a literature review]
Michela Di Renzo
Dipartimento di Medicina Interna e Scienze Immunologiche, Sezione di Medicina III, Universita degli Studi di Siena
Ann Ital Med Int 20:58-61. 2005
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- Common variable immunodeficiency: a review
M Di Renzo
Department of Clinical Medicine and Immunological Sciences, Division of Internal Medicine, University of Siena, I 53100 Siena, Italy
Clin Exp Med 3:211-7. 2004
..Most patients are diagnosed as adults and delay in the recognition of the disease is common. Several T and B cell defects have been described, although the underlying cause is still unknown...
- Takayasu's arteritis: case report of a patient with recurrent subclavian steal syndrome
Michela Di Renzo
Dipartimento di Medicina Interna e Scienze Immunologiche, Policlinico Le Scotte, 53100, Siena, Italy
Heart Vessels 19:94-7. 2004
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- Thymoma and immunodeficiency
Michela Di Renzo
Department of Internal Medicine and Immunological Sciences, University of Siena, Siena, Italy
N Z Med J 117:U750. 2004
- ECP-treated lymphocytes of chronic graft-versus-host disease patients undergo apoptosis which involves both the Fas/FasL system and the Bcl-2 protein family
M Di Renzo
Department of Internal Medicine and Immunological Sciences, University of Siena, 53100 Siena, Italy
Arch Dermatol Res 295:175-82. 2003
..In conclusion, in patients affected by cGVHD, ECP induced apoptosis of lymphocytes with the involvement of both the Fas/FasL system and the Bcl-2 protein family...
- Enhanced apoptosis of peripheral blood mononuclear cells in cardiac transplanted patients undergoing chronic immunosuppressive treatment
M Di Renzo
Istituto di Semeiotica Medica, Policlinico Le Scotte, Viale Bracci, University of Siena, 53100 Siena, Italy
Transpl Immunol 10:269-75. 2002
..Our findings suggest that in cardiac transplanted patients PBMC undergo enhanced spontaneous apoptosis, which may contribute to prevent allograft rejection...
- Enhanced T cell apoptosis in common variable immunodeficiency: negative role of the fas/fasligand system and of the Bcl-2 family proteins and possible role of TNF-RS
M Di Renzo
Division of Clinical Immunology, The Mount Sinai Medical Center, 1425 Madison Avenue, New York City, New York, USA
Clin Exp Immunol 125:117-22. 2001
..Our data suggest that the increased expression of both TNF-Rs on T cells may be one of the mechanisms responsible for the accelerated T cell apoptosis in CVI...
Myelodysplasia and Good syndrome. A case reportM Di Renzo
U O di Medicina III, Policlinico Le Scotte, Viale Bracci 16, Siena, Italy
Clin Exp Med 8:171-3. 2008
..A bone marrow biopsy revealed a myelodysplastic syndrome. The patient started cyclosporine and the anaemia gradually improved, achieving transfusion independence...
