Charalambos D Partidos

Summary

Publications

  1. ncbi request reprint A synthetic HIV-1 Tat protein breaches the skin barrier and elicits Tat-neutralizing antibodies and cellular immunity
    Charalambos D Partidos
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, Strasbourg, France
    Eur J Immunol 34:3723-31. 2004
  2. pmc Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine
    Charalambos D Partidos
    Inviragen, Inc, Madison, 6502 Odana Rd, Madison, WI 53719, USA
    Vaccine 30:4638-43. 2012
  3. doi request reprint Immunomodulatory consequences of ODN CpG-polycation complexes
    Charalambos D Partidos
    CNRS UPR 9021, Institut de Biologie Moleculaire et Cellulaire, Strasbourg, France
    Methods 49:328-33. 2009
  4. pmc Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling
    Charalambos D Partidos
    Inviragen, Inc, Madison, 6502 Odana Rd, Madison, WI 53719, United States
    Vaccine 29:3067-73. 2011
  5. ncbi request reprint The binding affinity of double-stranded RNA motifs to HIV-1 Tat protein affects transactivation and the neutralizing capacity of anti-Tat antibodies elicited after intranasal immunization
    Charalambos D Partidos
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, Strasbourg, France
    Eur J Immunol 35:1521-9. 2005
  6. ncbi request reprint A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses
    Anne Sophie Beignon
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Vet Immunol Immunopathol 104:273-80. 2005
  7. ncbi request reprint Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses
    Davide Pantarotto
    Institut de Biologie Moleculaire et Cellulaire, UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, 15 rue Rene Descartes, 67084 Strasbourg, France
    Chem Biol 10:961-6. 2003
  8. ncbi request reprint Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties
    Alberto Bianco
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France
    J Am Chem Soc 127:58-9. 2005
  9. ncbi request reprint Modulation of immune responses with transcutaneously deliverable adjuvants
    Charalambos D Partidos
    UPR 9021, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, CNRS, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Vaccine 22:2385-90. 2004
  10. doi request reprint Immunogenicity and efficacy of chimeric dengue vaccine (DENVax) formulations in interferon-deficient AG129 mice
    Joseph N Brewoo
    Inviragen, Inc, Madison, WI, United States
    Vaccine 30:1513-20. 2012

Collaborators

Detail Information

Publications18

  1. ncbi request reprint A synthetic HIV-1 Tat protein breaches the skin barrier and elicits Tat-neutralizing antibodies and cellular immunity
    Charalambos D Partidos
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, Strasbourg, France
    Eur J Immunol 34:3723-31. 2004
    ..Transcutaneous immunization may be advantageous for the non-invasive delivery of other HIV candidate vaccine antigens...
  2. pmc Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine
    Charalambos D Partidos
    Inviragen, Inc, Madison, 6502 Odana Rd, Madison, WI 53719, USA
    Vaccine 30:4638-43. 2012
    ..These findings highlight the potential of the CHIKV/IRES vaccine to protect humans against not only CHIKV but also against ONNV-induced disease...
  3. doi request reprint Immunomodulatory consequences of ODN CpG-polycation complexes
    Charalambos D Partidos
    CNRS UPR 9021, Institut de Biologie Moleculaire et Cellulaire, Strasbourg, France
    Methods 49:328-33. 2009
    ..Overall, our findings together with published data support the view that for harnessing the beneficial effects of ODN CpGs a careful consideration has to be given depending on the target intervention...
  4. pmc Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling
    Charalambos D Partidos
    Inviragen, Inc, Madison, 6502 Odana Rd, Madison, WI 53719, United States
    Vaccine 29:3067-73. 2011
    ....
  5. ncbi request reprint The binding affinity of double-stranded RNA motifs to HIV-1 Tat protein affects transactivation and the neutralizing capacity of anti-Tat antibodies elicited after intranasal immunization
    Charalambos D Partidos
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, Strasbourg, France
    Eur J Immunol 35:1521-9. 2005
    ....
  6. ncbi request reprint A peptide vaccine administered transcutaneously together with cholera toxin elicits potent neutralising anti-FMDV antibody responses
    Anne Sophie Beignon
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Vet Immunol Immunopathol 104:273-80. 2005
    ..However, experiments in target species will be required to confirm the potential of this simple vaccination procedure in livestock...
  7. ncbi request reprint Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses
    Davide Pantarotto
    Institut de Biologie Moleculaire et Cellulaire, UPR 9021 CNRS, Immunologie et Chimie Thérapeutiques, 15 rue Rene Descartes, 67084 Strasbourg, France
    Chem Biol 10:961-6. 2003
  8. ncbi request reprint Cationic carbon nanotubes bind to CpG oligodeoxynucleotides and enhance their immunostimulatory properties
    Alberto Bianco
    Institut de Biologie Moleculaire et Cellulaire, UPR9021 CNRS, Immunologie et Chimie Thérapeutiques, 67084 Strasbourg, France
    J Am Chem Soc 127:58-9. 2005
    ..Functionalized cationic carbon nanotubes are able to form a stable complex with CpG ODN based on charge interaction and to increase the immunostimulatory activity of CpG motifs...
  9. ncbi request reprint Modulation of immune responses with transcutaneously deliverable adjuvants
    Charalambos D Partidos
    UPR 9021, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, CNRS, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Vaccine 22:2385-90. 2004
    ..In this review we give a brief overview of transcutaneously deliverable adjuvants and we discuss how they modulate immune responses to topically applied antigens...
  10. doi request reprint Immunogenicity and efficacy of chimeric dengue vaccine (DENVax) formulations in interferon-deficient AG129 mice
    Joseph N Brewoo
    Inviragen, Inc, Madison, WI, United States
    Vaccine 30:1513-20. 2012
    ....
  11. ncbi request reprint Carbon nanotubes: on the road to deliver
    Alberto Bianco
    UPR 9021, CNRS, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084, Strasbourg, France
    Curr Drug Deliv 2:253-9. 2005
    ..This opens new therapeutic and preventive opportunities to combat diseases. The scope of this review is to summarize our recent work in this rapidly growing field...
  12. pmc Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model
    Haiyan Chu
    Inviragen, Inc, Madison, WI 53719, USA
    Vaccine 31:3353-60. 2013
    ..Overall, our findings demonstrate the immunogenic potential of the CHIKV/IRES vaccine and highlight the important role that neutralizing antibodies play in protection against an acute CHIKV infection. ..
  13. ncbi request reprint Antigens onto bare skin: a 'painless' paradigm shift in vaccine delivery
    Charalambos D Partidos
    UPR 9021, CNRS, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084, Strasbourg, France
    Expert Opin Biol Ther 3:895-902. 2003
    ..However, despite these successes, there are several challenges ahead to be addressed before vaccines administered with a patch will be available over the counter...
  14. doi request reprint Cross-protective immunity against multiple influenza virus subtypes by a novel modified vaccinia Ankara (MVA) vectored vaccine in mice
    Joseph N Brewoo
    Inviragen, Inc, 6502 Odana Rd, Madison, WI 53719, USA
    Vaccine 31:1848-55. 2013
    ..Our findings highlight MVA as suitable vector to express multiple influenza antigens that could afford broad cross-protective immunity against multiple subtypes of influenza virus...
  15. ncbi request reprint Delivering vaccines into the skin without needles and syringes
    Charalambos D Partidos
    UPR 9021, CNRS, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Expert Rev Vaccines 2:753-61. 2003
    ..This article reviews current attempts to administer vaccines into the skin and discusses some of the scientific issues related to the emerging delivery technologies...
  16. ncbi request reprint Applying peptide antigens onto bare skin: induction of humoral and cellular immune responses and potential for vaccination
    Charalambos D Partidos
    UPR 9021, Institut de Biologie Moleculaire et Cellulaire, CNRS, 15 rue Rene Descartes, F 67084, Strasbourg, France
    J Control Release 85:27-34. 2002
    ..Therefore, they could be the most suitable candidate immunogens for skin immunisation. This review describes our recent observations on the immunogenicity of synthetic peptides applied onto bare skin in relation to vaccination...
  17. pmc Immunization onto bare skin with synthetic peptides: immunomodulation with a CpG-containing oligodeoxynucleotide and effective priming of influenza virus-specific CD4+ T cells
    Anne Sophie Beignon
    Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, F 67084 Strasbourg, France
    Immunology 105:204-12. 2002
    ..Furthermore, with the selection and combination of the appropriate type of adjuvants, immune responses can be modulated towards the desired type of Th phenotype...
  18. doi request reprint Dengue virus-specific CD4+ and CD8+ T lymphocytes target NS1, NS3 and NS5 in infected Indian rhesus macaques
    Katherine M Mladinich
    Microbiology Doctoral Training Program, University of Wisconsin Madison, 1326 Microbial Sciences, 1550 Linden Drive, Madison, WI 53706, USA
    Immunogenetics 64:111-21. 2012
    ....