J T Parissis

Summary

Publications

  1. ncbi request reprint Differences in clinical characteristics, management and short-term outcome between acute heart failure patients chronic obstructive pulmonary disease and those without this co-morbidity
    John T Parissis
    Second Department of Cardiology, Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Clin Res Cardiol 103:733-41. 2014
  2. ncbi request reprint Prognostic value of high sensitivity troponin T in patients with acutely decompensated heart failure and non-detectable conventional troponin T levels
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece Electronic address
    Int J Cardiol 168:3609-12. 2013
  3. ncbi request reprint Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality
    John T Parissis
    Second Cardiology Department, Attikon University Hospital, Athens, Greece
    Int J Cardiol 168:185-9. 2013
  4. doi request reprint Acute heart failure in patients with diabetes mellitus: clinical characteristics and predictors of in-hospital mortality
    John T Parissis
    Heart Failure Clinic and Secondary Cardiology Department, Attikon University Hospital, Athens, Greece
    Int J Cardiol 157:108-13. 2012
  5. ncbi request reprint Effects of levosimendan on markers of left ventricular diastolic function and neurohormonal activation in patients with advanced heart failure
    John T Parissis
    Second Department of Cardiology and Heart Failure Clinic, Attikon University Hospital, Athens, Greece
    Am J Cardiol 96:423-6. 2005
  6. ncbi request reprint Novel biologic mechanisms of levosimendan and its effect on the failing heart
    John T Parissis
    University of Athens and Attikon General Hospital, Heart Failure Clinic and Second Cardiology Department, Navarinou 13, 15122 Maroussi, Athens, Greece
    Expert Opin Investig Drugs 17:1143-50. 2008
  7. ncbi request reprint Classical inotropes and new cardiac enhancers
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Heart Fail Rev 12:149-56. 2007
  8. ncbi request reprint Depression in chronic heart failure: novel pathophysiological mechanisms and therapeutic approaches
    John T Parissis
    Attikon University Hospital Heart Failure Clinic, Aftocratoros Irakliou 17, 15122, Maroussi, Athens, Greece
    Expert Opin Investig Drugs 14:567-77. 2005
  9. ncbi request reprint Anti-cytokine therapies in chronic heart failure: is this concept still alive?
    John T Parissis
    Second Department of Cardiology, Attikon University Hospital, Athens, Greece
    Hellenic J Cardiol 46:101-7. 2005
  10. ncbi request reprint Levosimendan for the treatment of acute heart failure syndromes
    John T Parissis
    Second Cardiology Department, Heart Failure Clinic, Attikon Univesity Hospital, Athens, Greece
    Expert Opin Pharmacother 6:2741-51. 2005

Detail Information

Publications68

  1. ncbi request reprint Differences in clinical characteristics, management and short-term outcome between acute heart failure patients chronic obstructive pulmonary disease and those without this co-morbidity
    John T Parissis
    Second Department of Cardiology, Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Clin Res Cardiol 103:733-41. 2014
    ..Data about respiratory disorders and related medications were available for 4,616 patients with AHF...
  2. ncbi request reprint Prognostic value of high sensitivity troponin T in patients with acutely decompensated heart failure and non-detectable conventional troponin T levels
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece Electronic address
    Int J Cardiol 168:3609-12. 2013
    ..The aim of the present study was to determine the prognostic utility of hs-TnΤ levels in patients admitted to hospital for acutely decompensated heart failure (ADHF) and non-detectable conventional TnΤ levels...
  3. ncbi request reprint Gender-related differences in patients with acute heart failure: management and predictors of in-hospital mortality
    John T Parissis
    Second Cardiology Department, Attikon University Hospital, Athens, Greece
    Int J Cardiol 168:185-9. 2013
    ..The ALARM-HF survey is the first to include a cohort of 4953 patients hospitalized for AHF in 666 hospitals in 6 European countries, Mexico and Australia...
  4. doi request reprint Acute heart failure in patients with diabetes mellitus: clinical characteristics and predictors of in-hospital mortality
    John T Parissis
    Heart Failure Clinic and Secondary Cardiology Department, Attikon University Hospital, Athens, Greece
    Int J Cardiol 157:108-13. 2012
    ....
  5. ncbi request reprint Effects of levosimendan on markers of left ventricular diastolic function and neurohormonal activation in patients with advanced heart failure
    John T Parissis
    Second Department of Cardiology and Heart Failure Clinic, Attikon University Hospital, Athens, Greece
    Am J Cardiol 96:423-6. 2005
    ..Thus, levosimendan seems to be effective in improving left ventricular diastolic function and reducing neurohormonal activation in patients with severe heart failure...
  6. ncbi request reprint Novel biologic mechanisms of levosimendan and its effect on the failing heart
    John T Parissis
    University of Athens and Attikon General Hospital, Heart Failure Clinic and Second Cardiology Department, Navarinou 13, 15122 Maroussi, Athens, Greece
    Expert Opin Investig Drugs 17:1143-50. 2008
    ..Levosimendan, the most well-studied calcium sensitizer in the real clinical practice, produces greater hemodynamic and symptomatic improvement in patients with acute heart failure than traditional inotropes...
  7. ncbi request reprint Classical inotropes and new cardiac enhancers
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Heart Fail Rev 12:149-56. 2007
    ..More data are needed regarding patient selection and the optimum regimen and dosing of levosimendan before this treatment modality become the first line therapy of acutely decompensated chronic heart failure patients...
  8. ncbi request reprint Depression in chronic heart failure: novel pathophysiological mechanisms and therapeutic approaches
    John T Parissis
    Attikon University Hospital Heart Failure Clinic, Aftocratoros Irakliou 17, 15122, Maroussi, Athens, Greece
    Expert Opin Investig Drugs 14:567-77. 2005
    ....
  9. ncbi request reprint Anti-cytokine therapies in chronic heart failure: is this concept still alive?
    John T Parissis
    Second Department of Cardiology, Attikon University Hospital, Athens, Greece
    Hellenic J Cardiol 46:101-7. 2005
  10. ncbi request reprint Levosimendan for the treatment of acute heart failure syndromes
    John T Parissis
    Second Cardiology Department, Heart Failure Clinic, Attikon Univesity Hospital, Athens, Greece
    Expert Opin Pharmacother 6:2741-51. 2005
    ..The most common adverse effects of levosimendan treatment are hypotension and headache. Overall, levosimendan represents an effective and safe option for the treatment of decompensated heart failure patients...
  11. ncbi request reprint Depression in coronary artery disease: novel pathophysiologic mechanisms and therapeutic implications
    John T Parissis
    Second Department of Cardiology, Attikon University Hospital, Aftokratoros Irakliou 17, 15122 Maroussi, Athens, Greece
    Int J Cardiol 116:153-60. 2007
    ....
  12. ncbi request reprint Clinical and prognostic implications of self-rating depression scales and plasma B-type natriuretic peptide in hospitalised patients with chronic heart failure
    J T Parissis
    Heart Failure Clinic, Second Department of Cardiology, Attikon University Hospital, Athens, Greece
    Heart 94:585-9. 2008
    ..Depression is common among patients with chronic heart failure (CHF) and has been independently associated with a poorer prognosis...
  13. pmc Effects of serial levosimendan infusions on left ventricular performance and plasma biomarkers of myocardial injury and neurohormonal and immune activation in patients with advanced heart failure
    J T Parissis
    Second Department of Cardiology and Heart Failure Clinic, Attikon University Hospital, Athens, Greece
    Heart 92:1768-72. 2006
    ..The role, however, of repeated levosimendan infusions in the management of these patients has not yet been properly assessed...
  14. ncbi request reprint Effects of levosimendan on right ventricular function in patients with advanced heart failure
    John T Parissis
    Second Cardiology Department, Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Am J Cardiol 98:1489-92. 2006
    ..05). In conclusion, levosimendan could offer further therapeutic advantages in patients with advanced heart failure by improving systolic and diastolic RV function...
  15. ncbi request reprint Sertraline for the treatment of depression in coronary artery disease and heart failure
    John Parissis
    University of Athens, 17 Aftokratoros, Irakliou St 15122 Maroussi, Athens, Greece
    Expert Opin Pharmacother 8:1529-37. 2007
    ..Intervention with sertraline has the potential to provide depressed patients with cardiac disease relief from their depressive symptoms, improvement in quality of life and a potential benefit in their cardiovascular risk profile...
  16. ncbi request reprint Effects of levosimendan on flow-mediated vasodilation and soluble adhesion molecules in patients with advanced chronic heart failure
    John T Parissis
    Second Department of Cardiology, Attikon University Hospital, Rimini 1, 12461 Chaidari, Athens, Greece
    Atherosclerosis 197:278-82. 2008
    ..We sought to investigate whether the calcium sensitizer levosimendan affects beneficially endothelial function and attenuates the deleterious effects of soluble adhesion molecules in patients with advanced CHF...
  17. ncbi request reprint Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy
    John T Parissis
    Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Centre Athens, Greece
    Eur J Cardiovasc Prev Rehabil 12:164-8. 2005
    ....
  18. doi request reprint Clinical and prognostic value of Duke's Activity Status Index along with plasma B-type natriuretic peptide levels in chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    John T Parissis
    Heart Failure Clinic and Second Department of Cardiology, Attikon University Hospital, Athens, Greece
    Am J Cardiol 103:73-5. 2009
    ..0001). In conclusion, functional status assessment by the DASI bears prognostic value, and its combination with plasma BNP may provide quite specific risk stratification in patients with chronic HF...
  19. ncbi request reprint Levosimendan: from basic science to clinical practice
    John T Parissis
    Heart Failure Clinic and Second Cardiology Department, Attikon University Hospital, Maroussi, Athens, Greece
    Heart Fail Rev 14:265-75. 2009
    ....
  20. doi request reprint Clinical characteristics and predictors of in-hospital mortality in acute heart failure with preserved left ventricular ejection fraction
    John T Parissis
    Heart Failure Clinic and Secondary Cardiology Department, Attikon University Hospital, Athens, Greece
    Am J Cardiol 107:79-84. 2011
    ....
  21. ncbi request reprint Elevated plasma amylase levels in advanced chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy: correlation with circulating interleukin-6 activity
    John T Parissis
    First Department of Cardiology, Amalia Fleming Hospital, Athens, Greece
    J Interferon Cytokine Res 23:329-33. 2003
    ..However, the lack of association between plasma IL-6 and amylase levels in mild heart failure patients indicates an independent correlation of each variable with the functional status of the disease...
  22. ncbi request reprint Inotropes in cardiac patients: update 2011
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Curr Opin Crit Care 16:432-41. 2010
    ..This review summarizes all the current knowledge about the use of conventional and new inotropic agents in various clinical entities of critically ill patients...
  23. ncbi request reprint Plasma profiles of peripheral monocyte-related inflammatory markers in patients with arterial hypertension. Correlations with plasma endothelin-1
    John T Parissis
    Department of Cardiology, Athens Euroclinic, Greece
    Int J Cardiol 83:13-21. 2002
    ....
  24. ncbi request reprint Plasma profiles of circulating granulocyte-macrophage colony-stimulating factor and soluble cellular adhesion molecules in acute myocardial infarction. Contribution to post-infarction left ventricular dysfunction
    John T Parissis
    First Department of Cardiology, Amalia Fleming Hospital, Athens Greece
    Eur Cytokine Netw 15:139-44. 2004
    ..These monocyte-related inflammatory mediators may actively contribute to the pathophysiology of the disease and post-infarction cardiac dysfunction...
  25. ncbi request reprint Serum profiles of C-C chemokines in acute myocardial infarction: possible implication in postinfarction left ventricular remodeling
    John T Parissis
    First Department of Cardiology, Amalia Fleming Hospital, Athens, Greece
    J Interferon Cytokine Res 22:223-9. 2002
    ..The elevation of these chemotactic inflammatory factors may actively contribute to the pathophysiology of the disease and the subsequent left ventricular remodeling...
  26. doi request reprint Plasma B-type natriuretic peptide and anti-inflammatory cytokine interleukin-10 levels predict adverse clinical outcome in chronic heart failure patients with depressive symptoms: a 1-year follow-up study
    John T Parissis
    Second Department of Cardiology, Heart Failure Clinic, Attikon University Hospital, 15122 Maroussi, Athens, Greece
    Eur J Heart Fail 11:967-72. 2009
    ..To assess the prognostic value of a wide spectrum of neurohormonal and inflammatory markers along with functional status and exercise capacity, in hospitalized chronic heart failure (CHF) patients with depressive symptoms...
  27. ncbi request reprint Comparison of circulating proinflammatory cytokines and soluble apoptosis mediators in patients with chronic heart failure with versus without symptoms of depression
    John T Parissis
    Heart Failure Clinic, Amalia Fleming Hospital, Athens, Greece
    Am J Cardiol 94:1326-8. 2004
    ..A disregulated cytokine network and activated apoptosis signaling molecules may be actively implicated in the pathophysiology of chronic emotional distress and depressive symptoms in patients with heart failure...
  28. pmc Self-assessment of health status is associated with inflammatory activation and predicts long-term outcomes in chronic heart failure
    John T Parissis
    Heart Failure Clinic, Second Department of Cardiology, Attikon University Hospital, Navarinou 13, Maroussi, 15122 Athens, Greece
    Eur J Heart Fail 11:163-9. 2009
    ..We investigated the correlation between health status and inflammation burden as well as its long-term prognostic value in CHF outpatients...
  29. doi request reprint Acute pulmonary oedema: clinical characteristics, prognostic factors, and in-hospital management
    John T Parissis
    Heart Failure Clinic and Second Cardiology Department, Attikon University Hospital, University of Athens, Athens, Greece
    Eur J Heart Fail 12:1193-202. 2010
    ..This subanalysis examines the clinical profile, prognostic factors, and management of APE patients (n = 1820, 36.7%) included in the Acute Heart Failure Global Survey of Standard Treatment (ALARM-HF)...
  30. ncbi request reprint Effects of levosimendan versus dobutamine on inflammatory and apoptotic pathways in acutely decompensated chronic heart failure
    Stamatis Adamopoulos
    Second Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Cardiol 98:102-6. 2006
    ..05). In conclusion, the superiority of levosimendan over dobutamine in improving central hemodynamics and left ventricular performance in decompensated HF seems to be related to its anti-inflammatory and antiapoptotic effects...
  31. ncbi request reprint Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure
    Kallirrhoe Kourea
    Second Department of Cardiology and Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Atherosclerosis 199:215-21. 2008
    ..044). In conclusion, darbepoetin-alpha reduces circulating pro-inflammatory cytokine IL-6 and apoptotic mediator soluble Fas ligand in CHF patients with anemia, with a parallel improvement of cardiac performance and exercise capacity...
  32. ncbi request reprint A glossary of circulating cytokines in chronic heart failure
    S Adamopoulos
    Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Center, Zinonos 9, Halandri, 15234, Athens, Greece
    Eur J Heart Fail 3:517-26. 2001
    ....
  33. ncbi request reprint Growth hormone administration reduces circulating proinflammatory cytokines and soluble Fas/soluble Fas ligand system in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy
    Stamatis Adamopoulos
    Second Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    Am Heart J 144:359-64. 2002
    ....
  34. ncbi request reprint Carvedilol improves left atrial and left ventricular function and reserve in dilated cardiomyopathy after 1 year of treatment
    Ioannis Paraskevaidis
    Second Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    J Card Fail 13:108-13. 2007
    ..The aim of this study was to evaluate the effects of carvedilol therapy on left atrial (LA) function in patients with heart failure from nonischemic dilated cardiomyopathy...
  35. ncbi request reprint Effects of levosimendan on coronary artery flow and cardiac performance in patients with advanced heart failure
    Ignatios Ikonomidis
    Second Cardiology Department and Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Eur J Heart Fail 9:1172-7. 2007
    ..Levosimendan has inotropic and vasodilatory effects. We investigated the effects of levosimendan on coronary flow and associated changes in neurohormonal activation and cardiac performance in patients with advanced heart failure...
  36. doi request reprint Functional electrical stimulation is more effective in severe symptomatic heart failure patients and improves their adherence to rehabilitation programs
    Apostolos Karavidas
    Cardiology Department, General Hospital G Genimmatas, Athens, Greece
    J Card Fail 16:244-9. 2010
    ..This study compares the effectiveness of FES on exercise capacity, endothelial function, neurohormonal status, and emotional stress in New York Heart Association (NYHA) III-IV versus NYHA II patients...
  37. ncbi request reprint Usefulness of dobutamine-induced changes of the two-dimensional longitudinal deformation predict clinical and neurohumoral improvement in men after levosimendan treatment in acutely decompensated chronic heart failure
    Ioannis A Paraskevaidis
    Heart Failure Unit and Second Cardiology Department, Attikon University Hospital, Athens, Greece
    Am J Cardiol 102:1225-9. 2008
    ..In conclusion, dobutamine-induced changes in longitudinal systolic strain rate are associated with clinical and neurohumoral improvement after levosimendan treatment in patients with ADCHF...
  38. ncbi request reprint Prognostic value of tissue Doppler right ventricular systolic and diastolic function indexes combined with plasma B-type natriuretic Peptide in patients with advanced heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    Vasiliki Bistola
    Second Department of Cardiology and Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Am J Cardiol 105:249-54. 2010
    ..01) and increased BNP (p <0.05) predicted the combined end point. In conclusion, RV TDI indexes combined with increased plasma BNP additively predict adverse cardiac outcomes in advanced CHF...
  39. ncbi request reprint Effects of growth hormone on circulating cytokine network, and left ventricular contractile performance and geometry in patients with idiopathic dilated cardiomyopathy
    Stamatis Adamopoulos
    Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Center, Athens, Greece
    Eur Heart J 24:2186-96. 2003
    ....
  40. ncbi request reprint Levosimendan reduces plasma B-type natriuretic peptide and interleukin 6, and improves central hemodynamics in severe heart failure patients
    Stamos Kyrzopoulos
    Second Department of Cardiovascular Medicine and Laboratory of Molecular Immunology and Histocompatibility, Onassis Cardiac Surgery Center, Maroussi, Athens 15122, Greece
    Int J Cardiol 99:409-13. 2005
    ..This study investigates whether levosimendan-induced hemodynamic improvement of CHF patients is related to the respective changes of NT-proBNP and IL-6 levels...
  41. ncbi request reprint Prolonged activation of tumor necrosis factor (TNF)-alpha and its soluble receptors in chronic heart failure patients both in the compensated and decompensated state. Interplay between their levels and metalloproteinase-3
    Dimitrios Tziakas
    Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece
    Eur Cytokine Netw 15:231-9. 2004
    ..The second goal of this study was to determine if a relationship exists between serum MMPs profiles (MMP-1, MMP-2, MMP-3) and circulating TNF-alpha or its soluble receptors...
  42. doi request reprint Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    John T Parissis
    Second Department of Cardiology and Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Am Heart J 155:751.e1-7. 2008
    ..We sought to investigate the effects of recombinant human erythropoietin analogue darbepoetin alpha on left (LV) and right ventricular (RV) function and neurohormonal activation in patients with CHF and anemia...
  43. ncbi request reprint Current drugs and medical treatment algorithms in the management of acute decompensated heart failure
    Filippos Triposkiadis
    Department of Cardiology, University of Thessaly Medical School, Larissa University Hospital, Larissa, Greece
    Expert Opin Investig Drugs 18:695-707. 2009
    ..New agents and strategies are under investigation in order to effectively reduce the mortality and morbidity in these patients...
  44. ncbi request reprint Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure
    John T Parissis
    Second Department of Cardiology, Amalia Fleming Hospital, Athens, Greece
    Am J Cardiol 93:1309-12. 2004
    ..These immunomodulatory effects may lead to improvement of symptoms and echocardiographic markers of cardiac contractile performance in these patients...
  45. ncbi request reprint Anti-inflammatory cytokine profile in acute coronary syndromes: behavior of interleukin-10 in association with serum metalloproteinases and proinflammatory cytokines
    Dimitrios N Tziakas
    Department of Cardiology, University of Thrace, Leoforos Dimokratias 116, Alexandroupolis 68100, Greece
    Int J Cardiol 92:169-75. 2003
    ....
  46. doi request reprint Plasma B-type natriuretic peptide reduction predicts long-term response to levosimendan therapy in acutely decompensated chronic heart failure
    Dimitrios Farmakis
    Second Department of Cardiology and Heart Failure Unit, Attiko University Hospital, Athens, Greece
    Int J Cardiol 139:75-9. 2010
    ..We sought to identify predictors of long-term response to levosimendan therapy among patients' baseline features and treatment-induced changes in acutely decompensated chronic heart failure (ADHF)...
  47. ncbi request reprint The predictive value of inflammatory and oxidative markers following the successful cardioversion of persistent lone atrial fibrillation
    Dionyssios I Leftheriotis
    ATTIKON University Hospital of Athens, Department of Cardiology, Athens, Greece
    Int J Cardiol 135:361-9. 2009
    ..The aim of this study is to evaluate these markers as predictors of sinus rhythm (SR) maintenance, in patients with persistent lone AF...
  48. doi request reprint Effects of darbepoetin-alpha on quality of life and emotional stress in anemic patients with chronic heart failure
    Kallirrhoe Kourea
    Second Department of Cardiology and Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Eur J Cardiovasc Prev Rehabil 15:365-9. 2008
    ..This study investigates the effects of recombinant human erythropoietin analog darbepoetin-alpha on quality of life and emotional stress, evaluated by relevant questionnaires in patients with CHF and anemia...
  49. ncbi request reprint Effects of levosimendan on quality of life and emotional stress in advanced heart failure patients
    John T Parissis
    Second Cardiology Department and Heart Failure Unit, University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Cardiovasc Drugs Ther 21:263-8. 2007
    ..However, its effects on quality of life, emotional stress and functional capacity of patients with advanced CHF have not been properly investigated...
  50. ncbi request reprint Effect of levosimendan on ventricular arrhythmias and prognostic autonomic indexes in patients with decompensated advanced heart failure secondary to ischemic or dilated cardiomyopathy
    Panayota Flevari
    Second Department of Cardiology, Attikon University Hospital, Athens, Greece
    Am J Cardiol 98:1641-5. 2006
    ..At the same time, it is associated with improvements in cardiac function and neurohormonal response. These findings may have important clinical and prognostic implications...
  51. ncbi request reprint Effects of Levosimendan on circulating markers of oxidative and nitrosative stress in patients with advanced heart failure
    John T Parissis
    Heart Failure Unit, Attikon University Hospital, Athens, Greece
    Atherosclerosis 195:e210-5. 2007
    ..We sought to investigate if the calcium sensitizer levosimendan beneficially modulates circulating markers of oxidative and nitrosative stress thus lessening their deleterious effects in patients with advanced CHF...
  52. ncbi request reprint Functional electrical stimulation improves endothelial function and reduces peripheral immune responses in patients with chronic heart failure
    Apostolos I Karavidas
    Department of Cardiology, General National Hospital, Athens, Greece
    Eur J Cardiovasc Prev Rehabil 13:592-7. 2006
    ..This study evaluates the impact of FES on endothelial function and peripheral markers of immune activation in patients with moderate to severe heart failure...
  53. ncbi request reprint Anti-inflammatory and anti-apoptotic effects of levosimendan in decompensated heart failure: a novel mechanism of drug-induced improvement in contractile performance of the failing heart
    Ioannis A Paraskevaidis
    2nd Department of Cardiology, Attikon University Hospital, Athens, Greece
    Curr Med Chem Cardiovasc Hematol Agents 3:243-7. 2005
    ....
  54. ncbi request reprint New aspects for the role of physical training in the management of patients with chronic heart failure
    Stamatis Adamopoulos
    Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Center, Athens, Greece
    Int J Cardiol 90:1-14. 2003
    ....
  55. doi request reprint Effects of Darbepoetin Alfa on plasma mediators of oxidative and nitrosative stress in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    John T Parissis
    Heart Failure Clinic, Attikon University Hospital, University of Athens, Greece
    Am J Cardiol 103:1134-8. 2009
    ..63, p <0.05). In conclusion, darbepoetin alfa attenuated deleterious effects of oxidative and nitrosative stress into the cardiovascular system of anemic patients with CHF, improving also cardiac function and exercise capacity...
  56. ncbi request reprint Selective serotonin re-uptake inhibitors for the treatment of depression in coronary artery disease and chronic heart failure: evidence for pleiotropic effects
    Ioannis Paraskevaidis
    Second Department of Cardiology and Heart Failure Clinic, University of Athens, Greece
    Cardiovasc Hematol Agents Med Chem 4:361-7. 2006
    ..These bio-modulatory properties of SSRIs may be translated into improvement of patient clinical outcomes beyond their anti-depressant action...
  57. ncbi request reprint New insight into "heart-hand" syndromes: a newly discovered chromosomal abnormality in a family with "heart-hand" syndrome
    Stamatis Adamopoulos
    Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Center, Riga Ferreou Str 18 20, Maroussi 15122, Athens, Greece
    Int J Cardiol 97:129-32. 2004
    ..This newly discovered chromosomal abnormality confirms once more the genetic heterogeneity of the syndrome...
  58. ncbi request reprint Severe anaemia and subcapital femur fracture in a patient with Left Ventricular Assist Device Heart Mate II: the cardiologist's management of this rare patient
    Bill D Gogas
    Second Department of Cardiology, Heart Failure Unit, Attikon University Hospital, 1 Rimini Street, Athens, Greece
    Eur J Heart Fail 11:806-8. 2009
    ..The patient was managed successfully by a team approach, which included a cardiologist, anaesthesiologist, orthopaedic surgeon, and LVAD technician...
  59. ncbi request reprint Anticoagulants, antiplatelets, and statins in heart failure
    Dimitrios Farmakis
    University of Athens Medical School, Attikon University Hospital, Athens, Greece
    Cardiol Clin 26:49-58, vi. 2008
    ..This article outlines the current knowledge regarding the use of antiplatelet and anticoagulant agents and statins in patients who have heart failure...
  60. ncbi request reprint Levosimendan therapy in decompensated chronic heart failure: favourable haemodynamic and neurohormonal effects but for how long?
    John T Parissis
    Eur J Heart Fail 8:215; author reply 218. 2006
  61. ncbi request reprint Anti-inflammatory effects of levosimendan in decompensated heart failure: impact on weight loss and anemia
    John T Parissis
    Am J Cardiol 95:923-4. 2005
  62. doi request reprint Overview of emerging pharmacologic agents for acute heart failure syndromes
    Leonardo De Luca
    Department of Cardiovascular Sciences, European Hospital, Rome, Italy
    Eur J Heart Fail 10:201-13. 2008
    ..There is, therefore, an unmet need for new pharmacologic agents for the early management of AHFS that may improve both short- and long-term outcomes...
  63. ncbi request reprint Levosimendan for the treatment of acute heart failure syndromes: time to identify subpopulations of responding patients
    John T Parissis
    Am J Cardiol 99:146-7. 2007
  64. ncbi request reprint Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration
    Dimitrios N Tziakas
    Cardiology Department, University of Thrace, Leoforos Dimokratias 116, GR 68100 Alexandroupolis, Greece
    Int J Cardiol 94:269-77. 2004
    ..The reduction of these factors by short-term atorvastatin administration may provide a new insight into the pleiotropic effects of statins on unstable coronary artery disease...
  65. ncbi request reprint Giant unruptured aneurysm of right valsalva sinus detected by magnetic resonance imaging
    John T Parissis
    Int J Cardiol 96:299-301. 2004
    ....
  66. ncbi request reprint An atypical left atrial myxoma causing intracavitary pressure gradient and typical diastolic transmitral flow of severe mitral stenosis
    John T Parissis
    Int J Cardiol 102:165-7. 2005
  67. ncbi request reprint Estrogen administration in patients with chronic heart failure: not ready for prime time
    Gerasimos Filippatos
    Eur J Heart Fail 5:113-6. 2003
  68. ncbi request reprint A rare case of large mediastinal germ cell tumor detected by echocardiography
    Spilios M Karas
    Int J Cardiol 101:159-61. 2005
    ..CT scanning and histological findings after tumor resection confirmed diagnosis. This case demonstrates the clinical importance of echocardiography in diagnosis of extra-cardiac masses...