Switching, cycling, and antidepressant-induced effects on cycle frequency and course of illness in adult bipolar disorder: a brief review and commentaryDemitri F Papolos
Albert Einstein College of Medicine, Bronx, New York, USA
J Child Adolesc Psychopharmacol 13:165-71. 2003
..This brief review of the adult literature addresses some of these key issues with the aim of encouraging further research in this area of clinical psychopharmacology...
Fear of harm, a possible phenotype of pediatric bipolar disorder: a dimensional approach to diagnosis for genotyping psychiatric syndromesDemitri Papolos
Juvenile Bipolar Research Foundation, 22 Crescent Road, Westport, CT 06880, USA
J Affect Disord 118:28-38. 2009
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- A strategy for identifying phenotypic subtypes: concordance of symptom dimensions between sibling pairs who met screening criteria for a genetic linkage study of childhood-onset bipolar disorder using the Child Bipolar Questionnaire
Demitri Papolos
The Juvenile Bipolar Research Foundation, Research Department, 550 Ridgewood Road, Maplewood, NJ 07040, USA
J Affect Disord 99:27-36. 2007
..This report presents data on the potential usefulness of these dimensions in genotyping...
- The child bipolar questionnaire: a dimensional approach to screening for pediatric bipolar disorder
Demitri Papolos
The Juvenile Bipolar Research Foundation, USA
J Affect Disord 95:149-58. 2006
..This report provides preliminary data on the reliability and validity of the CBQ...
- Obsessive fears about harm to self or others and overt aggressive behaviors in youth diagnosed with juvenile-onset bipolar disorder
Demitri Papolos
Juvenile Bipolar Research Foundation, 550 Ridgewood Rd, Maplewood, NJ 07040, United States
J Affect Disord 89:99-105. 2005
..Obsessive fear-of-harm, either fear of doing harm or fear of harm coming to self, may be closely associated with aggressive behaviors in juvenile-onset bipolar disorder...
- Neuropsychological factors differentiating treated children with pediatric bipolar disorder from those with attention-deficit/hyperactivity disorder
STEVEN MATTIS
Department of Neurology, Weill Cornell Medical Center, New York, NY, USA
J Clin Exp Neuropsychol 33:74-84. 2011
..The findings support the contention that processing speed, intraindividual variability, and slower and more variable reaction time as interstimulus interval lengthens are likely specific endophenotypes of PBD...
- Factors associated with parent-reported suicide threats by children and adolescents with community-diagnosed bipolar disorder
Demitri Papolos
The Juvenile Bipolar Research Foundation, 550 Ridgewood Road, Maplewood, NJ 07040, USA
J Affect Disord 86:267-75. 2005
..This may have implications for treatment with antidepressant medication when the diagnosis of bipolar disorder may be present...
- Screening of PIP5K2A promoter region for mutations in bipolar disorder and schizophrenia
Pavla Stopkova
Department of Psychiatry and Behavioral Sciences, Division of Psychiatry Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Psychiatr Genet 15:223-7. 2005
..To analyze the promoter region of PIP5K2A, a phosphatidylinositol 4-phosphate 5-kinase that maps to 10p in a region linked to both bipolar disorder and schizophrenia...
- Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia
Pavla Stopkova
Psychiatric Clinic, First Medical Faculty, Charles University, Prague, Czech Republic
Biol Psychiatry 55:981-8. 2004
..One is PIK3C3, a member of the phosphatidylinositide 3-kinase family that maps closely to markers on 18q linked to both BD and SZ in a few studies...
- Increase in GSK3beta gene copy number variation in bipolar disorder
Herbert M Lachman
Department of Psychiatry and Behavioral Sciences, Division of Basic Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Am J Med Genet B Neuropsychiatr Genet 144:259-65. 2007
..002). The finding suggests that GSK3beta may be involved in BD susceptibility in some individuals and that CNVs in this and other candidate genes for psychiatric disorders should be analyzed as causative functional genetic variants...
- Polymorphism screening of PIP5K2A: a candidate gene for chromosome 10p-linked psychiatric disorders
Pavla Stopkova
Department of Psychiatry and Behavioral Sciences, Division of Psychiatry Research, Albert Einstein College of Medicine, New York 10461, USA
Am J Med Genet B Neuropsychiatr Genet 123:50-8. 2003
..These data suggest that the imperfect CT repeat in PIP5K2A intron 9 should be further investigated as a possible candidate allele for 10p12-linked psychiatric disorders...
- Analysis of synapsin III-196 promoter mutation in schizophrenia and bipolar disorder
Herbert M Lachman
Department of Psychiatry and Behavioral Sciences, Division of Psychiatry Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Neuropsychobiology 53:57-62. 2006
..The -196A allele results in a 6/8 base match to the core recognition octamer sequence for Oct-1, a member of the POU family of transcription factors...
