Effect of cigarette smoking on platelet aggregationBurak Pamukcu
Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, Istanbul, Turkey
Clin Appl Thromb Hemost 17:E175-80. 2011
..Cigarette smoking may increase platelet aggregation and cause atherothrombotic cardiovascular events. We aimed to investigate the impact of cigarette smoking on platelet function in patients with ischemic coronary heart disease (CHD)...
Metastatic Ewing's sarcoma involving the right ventricleBurak Pamukcu
Department of Cardiology, Istanbul Medicine Faculty of Istanbul University, Istanbul, Turkey
Turk Kardiyol Dern Ars 36:546-8. 2008
..The mass showed partial contrast enhancement, suggesting a malignant metastatic mass. Surgical resection was not considered due to accompanying lung metastasis and potentially poor outcome of the operation...
- [The relationship between aspirin resistance and endothelial dysfunction in patients with stable coronary artery disease]
Burak Pamukcu
Department of Cardiology, Istanbul Medical Faculty of Istanbul University, Istanbul, Turkey
Turk Kardiyol Dern Ars 36:103-7. 2008
..We investigated the relationship between aspirin-resistant platelet aggregation and endothelial dysfunction in patients with stable coronary artery disease...
- Relationship between the serum sCD40L level and aspirin-resistant platelet aggregation in patients with stable coronary artery disease
Burak Pamukcu
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Circ J 72:61-6. 2008
..Increased serum sCD40L may trigger platelet activation, so the aim of the present study was to determine the relation between sCD40L levels and aspirin-resistant platelet aggregation in patients with coronary atherosclerosis...
- Aspirin-resistant platelet aggregation in a cohort of patients with coronary heart disease
Burak Pamukcu
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Blood Coagul Fibrinolysis 18:461-5. 2007
..Monitoring of platelet function in patients with coronary heart disease may support the optimization of antiplatelet therapy with additional and/or alternative agents...
- The role of aspirin resistance on outcome in patients with acute coronary syndrome and the effect of clopidogrel therapy in the prevention of major cardiovascular events
Burak Pamukcu
Istanbul Faculty of Medicine, Department of Cardiology, Istanbul University, Hasan Halife Mahallesi Oksuzler Sokak No 9 K 2 D 4 Fatih, Istanbul, Turkey 34080
J Thromb Thrombolysis 22:103-10. 2006
..Aspirin resistance may increase up to more then threefold the risk of major cardiovascular events (MACE) in patients with stable coronary artery disease...
- Clinical relevance of aspirin resistance in patients with stable coronary artery disease: a prospective follow-up study (PROSPECTAR)
Burak Pamukcu
Istanbul Faculty of Medicine, Department of Cardiology, Istanbul University, Istanbul, Turkey
Blood Coagul Fibrinolysis 18:187-92. 2007
..The MACE prevalence increased during follow-up, however, just after cessation of clopidogrel therapy...
- Impact of genetic polymorphisms on platelet function and aspirin resistance
Burak Pamukcu
Istanbul University, Istanbul Faculty of Medicine, Department of Cardiology, Turkey
Blood Coagul Fibrinolysis 21:53-6. 2010
....
- Coronary flow reserve after L-thyroxine therapy in Hashimoto's thyroiditis patients with subclinical and overt hypothyroidism
Huseyin Oflaz
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Arpaemini M Tatlipinar C, No 64 D 5, Fatih, Istanbul, Turkey
Endocrine 32:264-70. 2007
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- Assessment of longitudinal left ventricular systolic function by different echocardiographic modalities in patients with newly diagnosed mild-to-moderate hypertension
Dursun Atilgan
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Anadolu Kardiyol Derg 10:247-52. 2010
..Therefore we evaluated longitudinal left ventricular myocardial function by tissue Doppler echocardiography; strain (S), strain rate (SR), tissue Doppler velocity (TDV) in newly diagnosed mild to moderate hypertensive patients...
- The role of exercise on platelet aggregation in patients with stable coronary artery disease: exercise induces aspirin resistant platelet activation
Burak Pamukcu
Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
J Thromb Thrombolysis 20:17-22. 2005
..The aim of our study was to determine the relation between exercise stress test and aspirin resistance in patients with stable coronary artery disease...
- Nebivolol prevents remodeling in a rat myocardial infarction model: an echocardiographic study
Guldem Olguner Mercanoglu
Department of Pharmacology, Faculty of Pharmacy, Yeditepe University, Istanbul, Turkey
Anadolu Kardiyol Derg 10:18-27. 2010
..We aimed to investigate the role of nebivolol treatment on VR after a MI in a rat ischemia-reperfusion model...
- Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease
Ebru Tirnaksiz
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, 34093, Turkey
J Thromb Thrombolysis 27:24-8. 2009
..Current evidence supports the preventive role of statins on platelet aggregation in patients with coronary heart disease...
- Relationship between left ventricular hypertrophy, hypertensive retinopathy, microalbuminuria and echocardiographic modalities in newly diagnosed hypertensive patients
Ahmet Kaya Bilge
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, 34390, Capa, Istanbul, Turkey
Int J Cardiovasc Imaging 26:405-12. 2010
..In hypertensive patients, LMF established by the measurement of S and SR, might be impaired and also related with end organ damage while global circumferential function is preserved...
- Influences of genetic variants in interleukin-15 gene and serum interleukin-15 levels on coronary heart disease
Cahide Gokkusu
Department of Biochemistry, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
Cytokine 49:58-63. 2010
..In conclusion, our study supports the hypothesis that genetic variation in IL-15 gene and IL-15 levels influence the risk of CHD. Further studies are needed to confirm our hypothesis...
- Endothelial function in patients with obstructive sleep apnea syndrome but without hypertension
Huseyin Oflaz
Department of Cardiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey
Respiration 73:751-6. 2006
..Obstructive sleep apnea syndrome (OSAS) influences endothelial function and causes hypertension...
- Coronary flow reserve is impaired in patients with adult growth hormone (GH) deficiency
Huseyin Oflaz
Deaprtment of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Clin Endocrinol (Oxf) 66:524-9. 2007
..We have used TTDE to evaluate endothelial function and coronary microvascular function in AGHD...
- The role of platelet glycoprotein IIIa polymorphism in the high prevalence of in vitro aspirin resistance in patients with intracoronary stent restenosis
Burak Pamukcu
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Am Heart J 149:675-80. 2005
..The aim of our study was to determine the relation between platelet glycoprotein IIIa (Pl A ) polymorphism and aspirin resistance in patients with intracoronary stent restenosis...
- Non-invasive evaluation of endothelial function in hypertensive elderly patients
Bulent Saka
Department of Internal Medicine, Istanbul Medical School, Istanbul University, 34270 Capa, Istanbul, Turkey
Arch Gerontol Geriatr 40:61-71. 2005
..Positive correlations with age and hypertension, and significant inverse correlation with FMD, makes carotid artery IMT a possible indicator of endothelial function...
- Changes in endothelial function before and after renal transplantation
Huseyin Oflaz
Department of Cardiology, Istanbul Faculty of Medicine, Istanbul University, Turkey
Transpl Int 19:333-7. 2006
..001). Our results also showed that RTx has provided improvement in endothelial function by eliminating the uremic environment although not in the early post-RTx period...
- A review of aspirin resistance; definition, possible mechanisms, detection with platelet function tests, and its clinical outcomes
Burak Pamukcu
Department of Cardiology, Istanbul University, Hasan Halife Mahallesi Oksuzler Sokak No 9 K 2 D 4 Fatih, Istanbul 34080, Turkey
J Thromb Thrombolysis 23:213-22. 2007
..The intent of this paper is to review the literature discussing possible mechanisms, determination techniques, and clinical effects of aspirin resistance...
- Biventricular diastolic dysfunction in patients with autosomal-dominant polycystic kidney disease
Huseyin Oflaz
Department of Cardiology, Istanbul School of Medicine, Istanbul University, Turkey
Kidney Int 68:2244-9. 2005
..CONCLUSION: Both hypertensive and normotensive patients with ADPKD show significant biventricular diastolic dysfunction, suggesting cardiac involvement very early in the course of ADPKD...
- Atrial and ventricular arryhthmogenic potential in Turner Syndrome
Ahmet B Sozen
Department of Cardiology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
Pacing Clin Electrophysiol 31:1140-5. 2008
..The aim of this study is to investigate the cardiac arrhythmogenic potential in patients with TS...
- The effects of nebivolol on apoptosis in a rat infarct model
Guldem Mercanoglu
Department of Pharmacology, Faculty of Pharmacy, Yeditepe University, Kayisdagi, Istanbul, Turkey
Circ J 72:660-70. 2008
..In the present study, nitric oxide (NO) was investigated to see if it mediated effects of nebivolol on apoptosis in the rat myocardial infarction (MI) model...
- Association of genetic variants in Methylenetetrahydrofolate Reductase and Paraoxonase-1 genes with homocysteine, folate and vitamin B12 in coronary artery disease
Makbule Aydin
Department of Neuroscience, The Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey
Mol Cell Biochem 325:199-208. 2009
....
- Association of metabolic syndrome with impaired heart rate recovery and low exercise capacity in young male adults
Ferhat Deniz
Department of Endocrinology and Metabolism, Etimesgut Military Hospital, Ankara, Turkey
Clin Endocrinol (Oxf) 66:218-23. 2007
..Impaired heart rate recovery (HRR) is a powerful predictor of overall mortality...
