Erum Khan

Summary

Affiliation: The Aga Khan University
Country: Pakistan

Publications

  1. ncbi request reprint Emergence of CTX-M Group 1-ESBL producing Klebsiella pneumonia from a tertiary care centre in Karachi, Pakistan
    Erum Khan
    Department of Pathology Microbiolog, Aga Khan University Hospital, Karachi, Pakistan
    J Infect Dev Ctries 4:472-6. 2010
  2. ncbi request reprint Emergence of vancomycin-resistant Enterococcus faecium at a tertiary care hospital in Karachi, Pakistan
    E Khan
    Dept of Pathology, The Aga Khan University Hospital, Karachi, Pakistan
    J Hosp Infect 52:292-6. 2002
  3. ncbi request reprint Trends in antimicrobial resistance in Shigella species in Karachi, Pakistan
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi 74800, Sindh, Pakistan
    J Infect Dev Ctries 3:798-802. 2009
  4. pmc Demographic and clinical features of dengue fever in Pakistan from 2003-2007: a retrospective cross-sectional study
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    PLoS ONE 5:e12505. 2010
  5. doi request reprint Co-circulations of two genotypes of dengue virus in 2006 out-break of dengue hemorrhagic fever in Karachi, Pakistan
    E Khan
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Stadium Road, P O Box 3500, Karachi 74800, Pakistan
    J Clin Virol 43:176-9. 2008
  6. ncbi request reprint Dengue outbreak in Karachi, Pakistan, 2006: experience at a tertiary care center
    E Khan
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Stadium Road, Karachi 74800, Pakistan
    Trans R Soc Trop Med Hyg 101:1114-9. 2007
  7. ncbi request reprint Clonal dissemination of vanA positive Enterococcus species in tertiary care hospitals in Karachi, Pakistan
    Naima Fasih
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 60:805-9. 2010
  8. pmc Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan
    Kauser Jabeen
    Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan
    BMC Infect Dis 10:101. 2010
  9. ncbi request reprint Evaluation of two ELISA assay kits against RT-PCR for diagnosis of dengue virus infection in a hospital setting in Karachi, Pakistan
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan
    J Pak Med Assoc 59:390-4. 2009
  10. ncbi request reprint Increased isolation of ESBL producing Klebsiella pneumoniae with emergence of carbapenem resistant isolates in Pakistan: report from a tertiary care hospital
    Erum Khan
    Department of Pathology Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan
    J Pak Med Assoc 60:186-90. 2010

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Emergence of CTX-M Group 1-ESBL producing Klebsiella pneumonia from a tertiary care centre in Karachi, Pakistan
    Erum Khan
    Department of Pathology Microbiolog, Aga Khan University Hospital, Karachi, Pakistan
    J Infect Dev Ctries 4:472-6. 2010
    ..Hence the aim of the study was first to characterise the genotypic content of these beta-lactamases and secondly to assess the clonal relationship of these isolates...
  2. ncbi request reprint Emergence of vancomycin-resistant Enterococcus faecium at a tertiary care hospital in Karachi, Pakistan
    E Khan
    Dept of Pathology, The Aga Khan University Hospital, Karachi, Pakistan
    J Hosp Infect 52:292-6. 2002
    ..Use of vancomycin and prolonged hospitalization were common features in all cases investigated...
  3. ncbi request reprint Trends in antimicrobial resistance in Shigella species in Karachi, Pakistan
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi 74800, Sindh, Pakistan
    J Infect Dev Ctries 3:798-802. 2009
    ..The disease is treated with antibiotics. Surveillance of antimicrobial resistance trends is essential owing to the global emergence of antimicrobial resistance...
  4. pmc Demographic and clinical features of dengue fever in Pakistan from 2003-2007: a retrospective cross-sectional study
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    PLoS ONE 5:e12505. 2010
    ..However, there is scarcity of data looking at the overall trend of dengue virus infection in the country. In this study, we examined annual trends, seasonality, and clinical features of dengue fever in the Pakistani population...
  5. doi request reprint Co-circulations of two genotypes of dengue virus in 2006 out-break of dengue hemorrhagic fever in Karachi, Pakistan
    E Khan
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Stadium Road, P O Box 3500, Karachi 74800, Pakistan
    J Clin Virol 43:176-9. 2008
    ..The status of dengue genotypes involved in the recent epidemic out-breaks in Pakistan is not well defined...
  6. ncbi request reprint Dengue outbreak in Karachi, Pakistan, 2006: experience at a tertiary care center
    E Khan
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Stadium Road, Karachi 74800, Pakistan
    Trans R Soc Trop Med Hyg 101:1114-9. 2007
    ..These findings may play an important role in the case definitions of future studies from this part of the world...
  7. ncbi request reprint Clonal dissemination of vanA positive Enterococcus species in tertiary care hospitals in Karachi, Pakistan
    Naima Fasih
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 60:805-9. 2010
    ..VRE) strains endemic in various hospitals of Karachi, to characterize the mechanism of glycopeptide resistance and assess the genetic relatedness, for understanding its transmission locally...
  8. pmc Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan
    Kauser Jabeen
    Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan
    BMC Infect Dis 10:101. 2010
    ..Resistance to quinolone and 3rd generation cephalosporin amongst non typhoidal Salmonellae (NTS) from Pakistan has been reported in this study...
  9. ncbi request reprint Evaluation of two ELISA assay kits against RT-PCR for diagnosis of dengue virus infection in a hospital setting in Karachi, Pakistan
    Erum Khan
    Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan
    J Pak Med Assoc 59:390-4. 2009
    ..To evaluate two commercially available ELISA-based kits against RT-PCR for the diagnosis of dengue virus infection in a Tertiary Care center in Karachi...
  10. ncbi request reprint Increased isolation of ESBL producing Klebsiella pneumoniae with emergence of carbapenem resistant isolates in Pakistan: report from a tertiary care hospital
    Erum Khan
    Department of Pathology Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan
    J Pak Med Assoc 60:186-90. 2010
    ..To report trends of extended spectrum beta lactamase (ESBL), multidrug resistant (MDR) ESBL and emergence of carbapenem resistant ESBL producing isolates of K. pneumoniae from Pakistan...
  11. ncbi request reprint Emergence of quinolone-resistant Neisseria gonorrhoeae in Pakistan
    Kauser Jabeen
    Pathology Microbiology Department, Aga Khan University, Karachi, Pakistan
    Int J STD AIDS 17:30-3. 2006
    ..We strongly urge the need of detection and documentation of the resistant gonococcal isolates, as in vitro resistance is associated with clinical failure...
  12. ncbi request reprint Inducible clindamycin resistance due to expression of erm genes in Staphylococcus aureus: report from a tertiary care Hospital Karachi, Pakistan
    Naima Fasih
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 60:750-3. 2010
    ..To assess the frequency of phenotypic expression of inducible resistance of clindamycin due to expression of erm genes, in clinical isolates of Staphylococcus aureus (S. aureus), by double disk diffusion test (D-test)...
  13. doi request reprint In vitro activity of tigecycline and other tetracyclines against carbapenem-resistant Acinetobacter species: report from a tertiary care centre in Karachi, Pakistan
    Sadia Shakoor
    Department of Clinical Microbiology, Aga Khan University Hospital, Karachi, Pakistan sadia shakkoor aku edu
    Chemotherapy 56:184-9. 2010
    ..Tigecycline minimum inhibitory concentration (MIC) was correlated with that of other tetracyclines to assess their predictive potential...
  14. ncbi request reprint Mixed Salmonella infection: a report of two cases from the Aga Khan University Hospital, Karachi
    Binish Arif Sultan
    Department of Pathology Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 63:524-6. 2013
    ..In highly endemic area, one must be aware of mixed Salmonella infections as inappropriate diagnosis of such infections may lead to treatment failure...
  15. ncbi request reprint Antibiotic susceptibility of pathogens isolated from patients with community-acquired respiratory tract infections in Pakistan--the active study
    Afia Zafar
    Department of Pathology and Microbiology, The Aga Khan University, Karachi, Pakistan
    J Ayub Med Coll Abbottabad 20:7-9. 2008
    ..This survey involved 9 countries. In this study we present the results from Pakistan where SP and HI only were tested...
  16. doi request reprint Prevalent genotypes of meticillin-resistant Staphylococcus aureus: report from Pakistan
    A Zafar
    Aga Khan University Hospital, Karachi, Pakistan
    J Med Microbiol 60:56-62. 2011
    ..These results suggest that an increase in genetic diversity occurred over the period 1997-2007 as a result of either microevolution or the importation of strains from surrounding areas...
  17. ncbi request reprint Wortmannin inhibits platelet aggregation produced by interaction of gamma-aminobutyric acid and the calcium tonophore, A23187
    S A Saeed
    Department of Physiology and Pharmacology, The Aga Khan University, Karachi, Pakistan
    Res Commun Mol Pathol Pharmacol 109:87-93. 2001
    ..These results suggest that the GABA effect is not mediated by traditional neuronal GABA receptors. We propose that wortmannin inhibits aggregation at a nexus downstream from membrane mechanisms triggered by the GABA-A23187 interaction...
  18. ncbi request reprint Macrolide and fluoroquinolone resistance in Helicobacter pylori isolates: an experience at a tertiary care centre in Pakistan
    Sana Rajper
    Department of Pathology Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 62:1140-4. 2012
    ..To assess fluoroquinolone and clarithromycin susceptibility pattern along with the types of genomic mutations involved in the resistance of Helicobacter pylori isolates...
  19. ncbi request reprint Line probe assay for detection of rifampicin and isoniazid resistant tuberculosis in Pakistan
    Joveria Qais Farooqi
    Department of Pathology Microbiology, Aga Khan University Hospital, Karachi
    J Pak Med Assoc 62:767-72. 2012
    ..To assess the efficacy of a line-probe assay delta (LiPA) as rapid diagnostic test for early detection of drug-resistant tuberculosis compared to conventional susceptibility methods in Pakistan...
  20. ncbi request reprint In vitro susceptibility of typhoidal Salmonellae against newer antimicrobial agents: a search for alternate treatment options
    Saba Qaiser
    Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan
    J Pak Med Assoc 61:462-5. 2011
    ..To determine the minimum inhibitory concentrations (MICs) of ceftriaxone, azithromycin, pefloxacin, cefipime and imipenem for Salmonella Typhi (S. Typhi) and Paratyphi...
  21. pmc Increasing Trend of Resistance to Penicillin, Tetracycline, and Fluoroquinolone Resistance in Neisseria gonorrhoeae from Pakistan (1992-2009)
    Kauser Jabeen
    Department of Pathology and Microbiology, Aga Khan University, Karachi 74800, Pakistan
    J Trop Med 2011:960501. 2011
    ..Ceftriaxone and cefixime should be the first line therapy; however periodic MICs should be determined to identify emergence of strains with reduced susceptibility...
  22. ncbi request reprint COMPARISON OF DIFFERENT PHENOTYPIC METHODS OF DETECTION OF METHICILLIN RESISTANCE IN Staphylococcus aureus WITH THE MOLECULAR DETECTION OF mec-A GENE
    Mohammad Zeeshan
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan
    J Coll Physicians Surg Pak 17:666-70. 2007
    ..However, Cefoxitin disc can be preferred especially for small laboratories because it is easy to perform, do not require special technique and media preparation is consequently more cost-effective...
  23. ncbi request reprint Changing trends of hepatitis B seromarkers amongst Pakistani population: a laboratory-based review
    Afia Zafar
    Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan
    J Pak Med Assoc 63:826-30. 2013
    ..To study the changing trends of hepatitis B markers tested at Aga Khan University Hospital clinical laboratory according to the internationally recognised classification of hepatitis B profile...
  24. doi request reprint Pulmonary nocardiosis: a comparative analysis of Nocardia asteroides and non-asteroides species
    Assad Amin
    Aga Khan University Hospital, PO Box 3500, Karachi 74800, Pakistan
    Trop Doct 42:94-6. 2012
    ..asteroides and non-asteroides species. Immunocompromised patients are more likely to have unfavorable outcomes...
  25. doi request reprint Rhinocladiella mackenziei as an emerging cause of cerebral phaeohyphomycosis in Pakistan: a case series
    Kauser Jabeen
    Department of Pathology Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan
    Clin Infect Dis 52:213-7. 2011
    ..Diabetes, head trauma, immunosuppressive treatment, and postpartum state were present in 4 cases. Two survivals and 3 fatalities occurred, with 1 patient lost to follow-up...
  26. ncbi request reprint Diagnosis of typhoid fever by Dot enzyme immunoassay in an endemic region
    E Khan
    Departments of Pathology and Community Health Sciences, Aga Khan University Hospital, Karachi
    J Pak Med Assoc 52:415-7. 2002
    ..To compare the results of Dot Enzyme Immunoassay (EIA) and concomitantly performed blood culture for the diagnosis of typhoid fever...
  27. ncbi request reprint DNA ploidy analyses in 218 consecutive Pakistani breast cancer patients: does it add anything?
    E Khan
    The Aga Khan University Medical Centre, Department of Pathology, Karachi, Pakistan
    Pathol Oncol Res 7:125-8. 2001
    ..The mean value of S-phase fraction for the aneuploids and the diploids was also insignificantly different. In conclusion DNA ploidy alone did not add much to predict tumor behaviour in terms of known pathologic variables...
  28. ncbi request reprint Impact of antibiotic usage on resistance in microorganisms; urinary tract infections with E-coli as a case in point
    N Sabir
    Department of Pathology, The Aga Khan University, Karachi
    J Pak Med Assoc 54:472-5. 2004
    ..coli in the urinary specimens. Data of all urinary samples, received at Aga Khan University Hospital between January 1995 and December 2002, was retrieved and analyzed. Specimens yielding E-coli as an isolate were included in this study...