Mohammad Perwaiz Iqbal

Summary

Affiliation: The Aga Khan University
Country: Pakistan

Publications

  1. pmc Smokeless tobacco use: a risk factor for hyperhomocysteinemia in a pakistani population
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 8:e83826. 2013
  2. pmc Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population
    Mohsin Yakub
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 7:e33222. 2012
  3. ncbi request reprint Association of alkaline phosphatase with acute myocardial infarction in a population with high prevalence of hypovitaminosis D
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan Electronic address
    Clin Chim Acta 425:192-5. 2013
  4. pmc Association of body iron status with the risk of premature acute myocardial infarction in a Pakistani population
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 8:e67981. 2013
  5. pmc Effects of betel nut on cardiovascular risk factors in a rat model
    Mohammad Perwaiz Iqbal
    Departments of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan
    BMC Cardiovasc Disord 12:94. 2012
  6. ncbi request reprint Lead pollution - a risk factor for cardiovascular disease in Asian developing countries
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    Pak J Pharm Sci 25:289-94. 2012
  7. ncbi request reprint Ascorbic acid contents of Pakistani fruits and vegetables
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Pak J Pharm Sci 19:282-5. 2006
  8. doi request reprint N-acetyl-B-D-glucosaminidase and inflammatory response after cardiopulmonary bypass
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University Hospital, Stadium Road, Karachi
    J Coll Physicians Surg Pak 18:74-7. 2008
  9. doi request reprint Folic acid and vitamin B6 deficiencies related hyperhomocysteinemia in apparently healthy Pakistani adults; is mass micronutrient supplementation indicated in this population?
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi
    J Coll Physicians Surg Pak 19:308-12. 2009
  10. ncbi request reprint Plaque formation reduction with glutathione monoester in mice fed on atherogenic diet
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, P O Box 3500, Karachi
    J Coll Physicians Surg Pak 16:571-5. 2006

Collaborators

Detail Information

Publications33

  1. pmc Smokeless tobacco use: a risk factor for hyperhomocysteinemia in a pakistani population
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 8:e83826. 2013
    ..The objective of this study was to evaluate the relationship of ST use with hyperhomocysteinemia in an urban Pakistani population...
  2. pmc Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population
    Mohsin Yakub
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 7:e33222. 2012
    ....
  3. ncbi request reprint Association of alkaline phosphatase with acute myocardial infarction in a population with high prevalence of hypovitaminosis D
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan Electronic address
    Clin Chim Acta 425:192-5. 2013
    ....
  4. pmc Association of body iron status with the risk of premature acute myocardial infarction in a Pakistani population
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 8:e67981. 2013
    ..In order to investigate whether increased body iron status has any relationship with the risk of premature AMI in Pakistani population, a case-control study was carried out...
  5. pmc Effects of betel nut on cardiovascular risk factors in a rat model
    Mohammad Perwaiz Iqbal
    Departments of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan
    BMC Cardiovasc Disord 12:94. 2012
    ....
  6. ncbi request reprint Lead pollution - a risk factor for cardiovascular disease in Asian developing countries
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    Pak J Pharm Sci 25:289-94. 2012
    ....
  7. ncbi request reprint Ascorbic acid contents of Pakistani fruits and vegetables
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Pak J Pharm Sci 19:282-5. 2006
    ..Since subclinical deficiency of vitamin C appears to be quite common in developing countries like Pakistan, there is a need to develop awareness among masses to consume fresh fruits and vegetables with high contents of vitamin C...
  8. doi request reprint N-acetyl-B-D-glucosaminidase and inflammatory response after cardiopulmonary bypass
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University Hospital, Stadium Road, Karachi
    J Coll Physicians Surg Pak 18:74-7. 2008
    ....
  9. doi request reprint Folic acid and vitamin B6 deficiencies related hyperhomocysteinemia in apparently healthy Pakistani adults; is mass micronutrient supplementation indicated in this population?
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi
    J Coll Physicians Surg Pak 19:308-12. 2009
    ..To determine the plasma/serum levels of homocysteine, and vitamins folate, B6 and B12, in Pakistani healthy adults...
  10. ncbi request reprint Plaque formation reduction with glutathione monoester in mice fed on atherogenic diet
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, P O Box 3500, Karachi
    J Coll Physicians Surg Pak 16:571-5. 2006
    ..To determine the role of glutathione monoester on reducing the development of plaque formation in an animal model...
  11. ncbi request reprint Additive effect of indomethacin and methotrexate on suppression of growth in rats
    M P Iqbal
    Department of Biochemistry, The Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
    Biopharm Drug Dispos 20:389-95. 1999
    ....
  12. ncbi request reprint N-acetyl-beta-D-glucosaminidase--a marker of reperfusion and a prognostic indicator in patients with acute myocardial infarction
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan
    Acta Cardiol 60:509-13. 2005
    ..The aim of this study is to investigate whether NAG could be used as an additional biochemical marker to predict myocardial reperfusion and to find out if its release following thrombolysis has a prognostic value as well...
  13. ncbi request reprint Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: interim analysis
    M P Iqbal
    Department of Biochemistry, The Aga Khan University, Karachi, Pakistan
    Exp Mol Med 32:84-7. 2000
    ..Results of this study indicate that colony stimulating factors (G-CSF and GM-CSF) induce white cell proliferation by increasing the levels of multiple forms of DHFR...
  14. ncbi request reprint Folinic acid protects against suppression of growth by methotrexate in mice
    M P Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
    Biopharm Drug Dispos 22:169-78. 2001
    ....
  15. ncbi request reprint Effect of methotrexate and folinic acid on accumulation of iron in mice
    M P Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan
    Med Hypotheses 61:444-5. 2003
    ..Decreased levels of iron in plasma in mice treated with MTX alone suggest decreased availability of iron to other tissues for their normal growth and development...
  16. ncbi request reprint N-acetyl-beta-D-glucosaminidase in acute myocardial infarction
    M Perwaiz Iqbal
    Department of Biological Sciences, The Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Exp Mol Med 35:275-8. 2003
    ..0001. No statistically significant differences in NAG activity were observed in patients in terms of gender, age, location of infarct, time from onset of chest pain to blood sampling in the hospital and size of the infarct...
  17. ncbi request reprint Effect of methotrexate and folinic acid on skeletal growth in mice
    M P Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan
    Acta Paediatr 92:1438-44. 2003
    ..To investigate whether chronic administration of medium doses of methotrexate (MTX) causes suppression of skeletal growth in young mice and to determine whether folinic acid supplementation could reverse this effect...
  18. ncbi request reprint Myoglobin--a marker of reperfusion and a prognostic indicator in patients with acute myocardial infarction
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan
    Clin Cardiol 27:144-50. 2004
    ..Although angiographic assessment remains the ideal procedure for determining patency, it is expensive, invasive, not within the reach of most patients in developing countries, and the long-term follow-up data are still sparse...
  19. ncbi request reprint Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction
    M Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Faculty of Health Sciences, The Aga Khan University, Karachi 74800, Pakistan
    Exp Mol Med 36:110-5. 2004
    ..52) or with serum levels of folate (P = 0.299). The results indicate that ACE G2350A polymorphism is not associated with risk of myocardial infarction in the Pakistani population investigated here...
  20. ncbi request reprint Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction
    M P Iqbal
    Department of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, PO Box 3500, Karachi 74800, Pakistan
    Nutr Metab Cardiovasc Dis 15:100-8. 2005
    ..A case-control study was carried out involving 224 AMI patients (age 30-70 years; 55 females and 169 males) and 126 normal healthy subjects (age 31-70 years; 35 females and 91 males)...
  21. pmc Association of blood lead (Pb) and plasma homocysteine: a cross sectional survey in Karachi, Pakistan
    Mohsin Yakub
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    PLoS ONE 5:e11706. 2010
    ..The objective of the present study was to assess the relationship of blood Pb to the risk of hyperhomocysteinemia in a low income urban population of Karachi, Pakistan...
  22. ncbi request reprint Low doses of colony-stimulating factors lead to resolution of neutropenia in cancer patients through increased levels of dihydrofolate reductase
    Mohammad Perwaiz Iqbal
    Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, Pakistan
    Pak J Pharm Sci 27:245-8. 2014
    ..Along with an increase in TLC, the levels of DHFR increased even at low doses of CSF suggesting that this might be one of the mechanisms for CSF-induced proliferation of leukocytes in neutropenic cancer patients...
  23. pmc Relationship between vitamin B12, folate and homocysteine levels and H. pylori infection in patients with functional dyspepsia: a cross-section study
    Shahid Rasool
    Section of Gastroenterology, Department of Medicine, Aga Khan University, Karachi 74800, Pakistan
    BMC Res Notes 5:206. 2012
    ..pylori infection. The aim of this study was to determine the impact of H. pylori infection on serum levels of vitamin B(12), folate and homocysteine in patients with functional dyspepsia (FD)...
  24. ncbi request reprint Admission creatine kinase as a prognostic marker in acute myocardial infarction
    Khawar Abbas Kazmi
    Department of Medicine, Aga Khan University, Karachi, Pakistan
    J Pak Med Assoc 59:819-22. 2009
    ....
  25. ncbi request reprint Polymorphism of HLA-DR and HLA-DQ in rheumatoid arthritis patients and clinical response to methotrexate--a hospital-based study
    Azra Arif I Ali
    Department of Biological and Biomedical Sciences3, Aga Khan University, Karachi
    J Pak Med Assoc 56:452-6. 2006
    ....
  26. ncbi request reprint Admission troponin T as a prognostic marker and it relationship to streptokinase treatment patients with acute myocardial infarction
    Khawar A Kazmi
    Department of Medicine, The Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Trop Doct 33:18-22. 2003
    ..The data suggest that the admission TnT level can be of value in risk stratification of patients with AMI...
  27. doi request reprint Dietary patterns are associated with hyperhomocysteinemia in an urban Pakistani population
    Mohsin Yakub
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan
    J Nutr 140:1261-6. 2010
    ..16; P < 0.001). A diet rich in fruits and uncooked vegetables decreased the risk of hyperhomocysteinemia, whereas diets rich in red meat, chicken, and tea with milk were positively associated with hyperhomocysteinemia...
  28. ncbi request reprint Does vitamin E have a role in treatment and prevention of anemia?
    Tanveer Jilani
    Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, P O Box 3500, Karachi, Pakistan
    Pak J Pharm Sci 24:237-42. 2011
    ....
  29. doi request reprint Vitamin E supplementation enhances hemoglobin and erythropoietin levels in mildly anemic adults
    Tanveer Jilani
    Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan
    Acta Haematol 119:45-7. 2008
  30. ncbi request reprint Anti-inflammatory role of methotrexate in adjuvant arthritis: effect on substance p and calcitonin gene-related Peptide in thymus and spleen
    Jawed Altaf Baig
    Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi
    J Coll Physicians Surg Pak 17:490-4. 2007
    ..Suppression of pro-inflammatory neuropeptides, such as CGRP and probably SP could be another mechanism by which MTX produces its anti-inflammatory effect in adjuvant arthritis...
  31. ncbi request reprint A simple micro method for determination of plasma levels of alpha tocopherol (Vitamin E) in Pakistani normal adults
    Naseema Mehbooali
    Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    Pak J Pharm Sci 21:361-5. 2008
    ..The method is rapid, convenient, reproduciable and relatively less hazardous compared to methods using xylene for the extraction of vitamin E. It can be routinely used to analyze as many as 20 plasma samples in about 2 hours time...
  32. ncbi request reprint Homocysteine levels in Pakistanis with myocardial infarction and normal healthy subjects
    Mohammad Perwaiz Iqbal
    J Coll Physicians Surg Pak 16:311; author reply 311. 2006