Manjunath P Pai

Summary

Publications

  1. ncbi request reprint Aminoglycoside dosing in patients by kidney function and area under the curve: the Sawchuk-Zaske dosing method revisited in the era of obesity
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, NY, USA Electronic address
    Diagn Microbiol Infect Dis 78:178-87. 2014
  2. pmc Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, New York, USA
    Antimicrob Agents Chemother 57:716-22. 2013
  3. ncbi request reprint Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults
    Manjunath P Pai
    Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, New York 12186, USA
    Pharmacotherapy 32:856-68. 2012
  4. pmc Clinical pharmacokinetics of oral controlled-release 5-fluorocytosine
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, 106 New Scotland Ave, O Brien 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 54:1237-41. 2010
  5. pmc Oseltamivir and oseltamivir carboxylate pharmacokinetics in obese adults: dose modification for weight is not necessary
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, New York 12208, USA
    Antimicrob Agents Chemother 55:5640-5. 2011
  6. pmc Simplified estimation of aminoglycoside pharmacokinetics in underweight and obese adult patients
    Manjunath P Pai
    Albany College of Pharmacy, 106 New Scotland Ave, O Brien Room 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:4006-11. 2011
  7. ncbi request reprint Estimating the glomerular filtration rate in obese adult patients for drug dosing
    Manjunath P Pai
    Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, NY 12208, USA
    Adv Chronic Kidney Dis 17:e53-62. 2010
  8. pmc Steady-state plasma pharmacokinetics of oral voriconazole in obese adults
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, 106 New Scotland Ave, O Brien 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:2601-5. 2011
  9. ncbi request reprint Pharmacokinetics and pharmacodynamics of extended-infusion piperacillin/tazobactam in adult patients with cystic fibrosis-related acute pulmonary exacerbations
    Jill M Butterfield
    Albany College of Pharmacy and Health Sciences, Albany, NY, USA
    J Antimicrob Chemother 69:176-9. 2014
  10. ncbi request reprint Vancomycin dosing in children and young adults: back to the drawing board
    Lauren Camaione
    Albany Medical Center, Albany, New York
    Pharmacotherapy 33:1278-87. 2013

Collaborators

  • Thomas P Lodise
  • Shaker A Mousa
  • Anne N Nafziger
  • Joseph S Bertino
  • Jill M Butterfield
  • Nimish Patel
  • Evan Zasowski
  • Scott Beegle
  • Joshua Farkas
  • Jonathan Rosen
  • Lauren Camaione
  • Ben Lomaestro
  • George L Drusano
  • Leon Cosler
  • Joseph Gottwald
  • Jason Cohen
  • Louise Ann McNutt
  • Wen Zhen Chen
  • Amy Mitchell-Van Steele
  • Kimberly Elliott
  • Keith A Rodvold
  • Thomas G Rosano

Detail Information

Publications15

  1. ncbi request reprint Aminoglycoside dosing in patients by kidney function and area under the curve: the Sawchuk-Zaske dosing method revisited in the era of obesity
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, NY, USA Electronic address
    Diagn Microbiol Infect Dis 78:178-87. 2014
    ..The purpose of this review is to provide healthcare providers a historical perspective of aminoglycoside therapeutic drug monitoring followed by an updated approach to improve dosing of these agents in obese adult patients. ..
  2. pmc Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, New York, USA
    Antimicrob Agents Chemother 57:716-22. 2013
    ..This preclinical model has the potential to aid with dose extrapolation for body size and improve assessment of the toxicology potential of antimicrobials in development...
  3. ncbi request reprint Drug dosing based on weight and body surface area: mathematical assumptions and limitations in obese adults
    Manjunath P Pai
    Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, New York 12186, USA
    Pharmacotherapy 32:856-68. 2012
    ....
  4. pmc Clinical pharmacokinetics of oral controlled-release 5-fluorocytosine
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, 106 New Scotland Ave, O Brien 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 54:1237-41. 2010
    ..The gastric absorption profile of 5FC-CR was well predicted by in vitro dissolution. Future exploration of a gastroretentive 5FC-CR formulation could overcome the marked lack of bioequivalence observed in the present study...
  5. pmc Oseltamivir and oseltamivir carboxylate pharmacokinetics in obese adults: dose modification for weight is not necessary
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, New York 12208, USA
    Antimicrob Agents Chemother 55:5640-5. 2011
    ..Since the systemic exposure of oseltamivir carboxylate is not reduced in class III obese adults with standard doses, a dose increment of oseltamivir is likely to be unnecessary...
  6. pmc Simplified estimation of aminoglycoside pharmacokinetics in underweight and obese adult patients
    Manjunath P Pai
    Albany College of Pharmacy, 106 New Scotland Ave, O Brien Room 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:4006-11. 2011
    ..45 liter/kg. Aminoglycoside dosing can be simplified across all weight strata with the use of lean body weight. The CKD-EPI equation best predicts aminoglycoside clearance...
  7. ncbi request reprint Estimating the glomerular filtration rate in obese adult patients for drug dosing
    Manjunath P Pai
    Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, NY 12208, USA
    Adv Chronic Kidney Dis 17:e53-62. 2010
    ..The role of the alternate body size descriptor, lean body weight to estimate CLcr in obese patients is reviewed...
  8. pmc Steady-state plasma pharmacokinetics of oral voriconazole in obese adults
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, 106 New Scotland Ave, O Brien 204, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:2601-5. 2011
    ..96) was identified between C(min) values and AUC(0-τ) values. Adjustment of voriconazole doses in individuals with class II obesity or greater does not appear to be necessary on the basis of body weight...
  9. ncbi request reprint Pharmacokinetics and pharmacodynamics of extended-infusion piperacillin/tazobactam in adult patients with cystic fibrosis-related acute pulmonary exacerbations
    Jill M Butterfield
    Albany College of Pharmacy and Health Sciences, Albany, NY, USA
    J Antimicrob Chemother 69:176-9. 2014
    ..The objectives of this study were to characterize the pharmacokinetics and pharmacodynamics of extended-infusion piperacillin/tazobactam in adult patients with CF and derive optimized piperacillin/tazobactam dosing recommendations...
  10. ncbi request reprint Vancomycin dosing in children and young adults: back to the drawing board
    Lauren Camaione
    Albany Medical Center, Albany, New York
    Pharmacotherapy 33:1278-87. 2013
    ....
  11. pmc Refining vancomycin protein binding estimates: identification of clinical factors that influence protein binding
    Jill M Butterfield
    Albany College of Pharmacy and Health Sciences, 106 New Scotland Avenue, Albany, NY 12208, USA
    Antimicrob Agents Chemother 55:4277-82. 2011
    ....
  12. ncbi request reprint Serum and urine pharmacokinetics of tigecycline in obese class III and normal weight adults
    Manjunath P Pai
    Albany College of Pharmacy and Health Sciences, Albany, NY, USA
    J Antimicrob Chemother 69:190-9. 2014
    ..To compare the serum and urine pharmacokinetics (PK) of intravenous tigecycline in obese class III (obese-C3) adults with those in normal weight (NW) adults...
  13. pmc Relationship between Time to Clinical Response and Outcomes among Pneumonia Outcomes Research Team (PORT) Risk Class III and IV Hospitalized Patients with Community-Acquired Pneumonia Who Received Ceftriaxone and Azithromycin
    Evan Zasowski
    Albany College of Pharmacy and Health Sciences, Albany, New York, USA
    Antimicrob Agents Chemother 58:3804-13. 2014
    ....
  14. pmc Pharmacokinetics and pharmacodynamics of once-daily administration of intravenous tobramycin in adult patients with cystic fibrosis hospitalized for an acute pulmonary exacerbation
    Jill M Butterfield
    Albany College of Pharmacy and Health Sciences, Albany, New York, USA
    Antimicrob Agents Chemother 57:5175-7. 2013
    ..Empirical tobramycin regimens of ≥15 mg/kg of body weight administered i.v. once daily should be evaluated for adult patients with CF to optimize outcomes. ..
  15. doi request reprint Vancomycin: we can't get there from here
    Nimish Patel
    Albany College of Pharmacy and Health Sciences, Albany, New York 12208, USA
    Clin Infect Dis 52:969-74. 2011
    ..We sought to characterize the pharmacodynamic profile of the more intensive vancomycin dosing regimens currently used in response to the recent vancomycin guidelines...