Tomoyuki Ozawa

Summary

Publications

  1. pmc Transpedicular hydroxyapatite grafting with indirect reduction for thoracolumbar burst fractures with neurological deficit: A prospective study
    Tomoaki Toyone
    Department of Orthopedic Surgery, Teikyo University Chiba Medical Center, 3426 3 Anesaki, Ichihara City, Chiba 299 0111, Japan
    Indian J Orthop 41:368-73. 2007
  2. doi request reprint Facet joint orientation difference between cephalad and caudad portions: a possible cause of degenerative spondylolisthesis
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Chiba, Japan
    Spine (Phila Pa 1976) 34:2259-62. 2009
  3. doi request reprint Subsequent vertebral fractures following spinal fusion surgery for degenerative lumbar disease: a mean ten-year follow-up
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 35:1915-8. 2010
  4. ncbi request reprint Changes in vertebral wedging rate between supine and standing position and its association with back pain: a prospective study in patients with osteoporotic vertebral compression fractures
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine Ichihara Hospital, 3426 3 Anesaki, Ichihara City, Chiba 299 0111, Japan
    Spine (Phila Pa 1976) 31:2963-6. 2006
  5. ncbi request reprint The treatment of acute thoracolumbar burst fractures with transpedicular intracorporeal hydroxyapatite grafting following indirect reduction and pedicle screw fixation: a prospective study
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine Ichihara Hospital, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 31:E208-14. 2006
  6. ncbi request reprint Patients' expectations and satisfaction in lumbar spine surgery
    Tomoaki Toyone
    Division of Orthopaedic Surgery, Kimitsu Chuo Hospital, Kisarazu City, Chiba, Japan
    Spine (Phila Pa 1976) 30:2689-94. 2005
  7. ncbi request reprint Anatomic changes in lateral spondylolisthesis associated with adult lumbar scoliosis
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine, Ichihara Hospital, Ichihara City, Japan
    Spine (Phila Pa 1976) 30:E671-5. 2005
  8. ncbi request reprint Low-back pain following surgery for lumbar disc herniation. A prospective study
    Tomoaki Toyone
    Division of Orthopaedic Surgery, Kimitsu Chuo Hospital, 1010 Sakurai, Kisarazu City, Chiba 292 8535, Japan
    J Bone Joint Surg Am 86:893-6. 2004
  9. doi request reprint Short-segment fixation without fusion for thoracolumbar burst fractures with neurological deficit can preserve thoracolumbar motion without resulting in post-traumatic disc degeneration: a 10-year follow-up study
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 38:1482-90. 2013
  10. ncbi request reprint Exposure of the nucleus pulposus to the outside of the anulus fibrosus induces nerve injury and regeneration of the afferent fibers innervating the lumbar intervertebral discs in rats
    Gen Inoue
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 31:1433-8. 2006

Collaborators

Detail Information

Publications34

  1. pmc Transpedicular hydroxyapatite grafting with indirect reduction for thoracolumbar burst fractures with neurological deficit: A prospective study
    Tomoaki Toyone
    Department of Orthopedic Surgery, Teikyo University Chiba Medical Center, 3426 3 Anesaki, Ichihara City, Chiba 299 0111, Japan
    Indian J Orthop 41:368-73. 2007
    ..We conducted a prospective consecutive series to evaluate the outcome of the management of acute thoracolumbar burst fractures by transpedicular hydroxyapatite (HA) grafting following indirect reduction and pedicle screw fixation...
  2. doi request reprint Facet joint orientation difference between cephalad and caudad portions: a possible cause of degenerative spondylolisthesis
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Chiba, Japan
    Spine (Phila Pa 1976) 34:2259-62. 2009
    ..OBJECTIVE.: To measure the orientation of the facet joints at both cephalad and caudad portions and to compare them between patients with degenerative spondylolisthesis (DS) and patients with lumbar spinal stenosis (LSS, controls)...
  3. doi request reprint Subsequent vertebral fractures following spinal fusion surgery for degenerative lumbar disease: a mean ten-year follow-up
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 35:1915-8. 2010
    ..Case-control study...
  4. ncbi request reprint Changes in vertebral wedging rate between supine and standing position and its association with back pain: a prospective study in patients with osteoporotic vertebral compression fractures
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine Ichihara Hospital, 3426 3 Anesaki, Ichihara City, Chiba 299 0111, Japan
    Spine (Phila Pa 1976) 31:2963-6. 2006
    ..Prospective consecutive series...
  5. ncbi request reprint The treatment of acute thoracolumbar burst fractures with transpedicular intracorporeal hydroxyapatite grafting following indirect reduction and pedicle screw fixation: a prospective study
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine Ichihara Hospital, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 31:E208-14. 2006
    ..Prospective consecutive series...
  6. ncbi request reprint Patients' expectations and satisfaction in lumbar spine surgery
    Tomoaki Toyone
    Division of Orthopaedic Surgery, Kimitsu Chuo Hospital, Kisarazu City, Chiba, Japan
    Spine (Phila Pa 1976) 30:2689-94. 2005
    ..Prospective consecutive series...
  7. ncbi request reprint Anatomic changes in lateral spondylolisthesis associated with adult lumbar scoliosis
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University School of Medicine, Ichihara Hospital, Ichihara City, Japan
    Spine (Phila Pa 1976) 30:E671-5. 2005
    ..Prospective consecutive series...
  8. ncbi request reprint Low-back pain following surgery for lumbar disc herniation. A prospective study
    Tomoaki Toyone
    Division of Orthopaedic Surgery, Kimitsu Chuo Hospital, 1010 Sakurai, Kisarazu City, Chiba 292 8535, Japan
    J Bone Joint Surg Am 86:893-6. 2004
    ..The purpose of the present prospective study was to assess the efficacy of discectomy in the treatment of low-back pain associated with lumbar disc herniation...
  9. doi request reprint Short-segment fixation without fusion for thoracolumbar burst fractures with neurological deficit can preserve thoracolumbar motion without resulting in post-traumatic disc degeneration: a 10-year follow-up study
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Ichihara City, Chiba, Japan
    Spine (Phila Pa 1976) 38:1482-90. 2013
    ..Prospective consecutive series...
  10. ncbi request reprint Exposure of the nucleus pulposus to the outside of the anulus fibrosus induces nerve injury and regeneration of the afferent fibers innervating the lumbar intervertebral discs in rats
    Gen Inoue
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 31:1433-8. 2006
    ....
  11. ncbi request reprint ISSLS prize winner: disc dynamic compression in rats produces long-lasting increases in inflammatory mediators in discs and induces long-lasting nerve injury and regeneration of the afferent fibers innervating discs: a pathomechanism for chronic discogeni
    Masayuki Miyagi
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 37:1810-8. 2012
    ..Animal model of intravertebral disc (IVD) degeneration...
  12. ncbi request reprint Vertebral compression exacerbates osteoporotic pain in an ovariectomy-induced osteoporosis rat model
    Miyako Suzuki
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Ichihara, Japan Department of Orthopaedic Surgery, Toho University Sakura Medical Center, Sakura, Japan Department of Orthopaedic Surgery, Wakayama Medical University Kihoku Hospital, Wakayama, Japan and Department of Orthopaedic Surgery, Kitasato University School of Medicine, Kanagawa, Japan
    Spine (Phila Pa 1976) 38:2085-91. 2013
    ..Basic pain study using osteoporotic rodent models...
  13. pmc Conservative and surgical treatment improves pain and ankle-brachial index in patients with lumbar spinal stenosis
    Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Yonsei Med J 54:999-1005. 2013
    ..The purpose of the study was to examine whether these treatments can improve ABI...
  14. ncbi request reprint Asymmetrical pedicle subtraction osteotomy for rigid degenerative lumbar kyphoscoliosis
    Tomoaki Toyone
    Department of Orthopaedic Surgery, Teikyo University Chiba Medical Center, Chiba, Japan
    Spine (Phila Pa 1976) 37:1847-52. 2012
    ..A prospectively study...
  15. pmc Up-regulation of TNFalpha in DRG satellite cells following lumbar facet joint injury in rats
    Masayuki Miyagi
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, 260 8670 Chiba, Japan
    Eur Spine J 15:953-8. 2006
    ..These data suggest that up-regulation of glial TNFalpha may be involved in the pathogenesis of facet joint pain...
  16. ncbi request reprint Glial phosphorylated p38 MAP kinase mediates pain in a rat model of lumbar disc herniation and induces motor dysfunction in a rat model of lumbar spinal canal stenosis
    Toshinori Ito
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 32:159-67. 2007
    ..Immunohistochemical and behavioral study using rat models of lumbar disc herniation and cauda equina syndrome...
  17. pmc L5 spinal nerve injury caused by misplacement of outwardly-inserted S1 pedicle screws
    Masahiro Inoue
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Eur Spine J 22:S461-5. 2013
    ..Despite this risk, to our knowledge this type of injury has never been reported as a case series...
  18. pmc Postoperative lumbar spinal stenosis after intertransverse fusion with granules of hydroxyapatite: a case report
    Gen Inoue
    Department of Orthopaedic Surgery, Kitasato University, School of Medicine, Minami Ku, Sagamihara, Kanagawa, Japan
    Diagn Pathol 7:153. 2012
    ..No tartrate-resistant acid phosphate (TRAP) -positive osteoclasts could be seen in the new bone, suggesting that the activity of osteoclasts in the new bone decreased during the seven years after the primary surgery...
  19. ncbi request reprint The degenerated lumbar intervertebral disc is innervated primarily by peptide-containing sensory nerve fibers in humans
    Tomoyuki Ozawa
    From the Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 31:2418-22. 2006
    ..Immunohistochemical study of the sensory innervation of the human lumbar intervertebral disc...
  20. ncbi request reprint Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back Pain and Modic Type 1 or Type 2 changes on MRI
    Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 31:1026-31. 2006
    ..Immunohistochemistry for tumor necrosis factor (TNF) and protein gene product (PGP) 9.5 in vertebral endplates of patients with discogenic low back pain and Modic Type 1 or Type 2 endplate changes on MRI...
  21. ncbi request reprint Incidence of Nocturnal Leg Cramps in Patients with Lumbar Spinal Stenosis before and after Conservative and Surgical Treatment
    Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Yonsei Med J 55:779-84. 2014
    ..However, there have been few reports on the relationship between nocturnal leg cramps and LSS, and it remains unknown whether conservative or surgical intervention has an impact on leg cramps in patients with LSS...
  22. doi request reprint In-vivo transfection of the proopiomelanocortin gene, precursor of endogenous endorphin, by use of radial shock waves alleviates neuropathic pain
    Tetsuhiro Ishikawa
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    J Orthop Sci 18:636-45. 2013
    ..The purpose of this study was to investigate the efficacy of proopiomelanocortin (POMC, a precursor of the endogenous opioid peptide β-endorphin) gene transfer by use of radial shock waves (RSWs) in a rat neuropathic pain model...
  23. ncbi request reprint Platelet-rich plasma combined with hydroxyapatite for lumbar interbody fusion promoted bone formation and decreased an inflammatory pain neuropeptide in rats
    Hiroto Kamoda
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 37:1727-33. 2012
    ..A prospective interventional trial, using a rat model of lumbar interbody fusion...
  24. ncbi request reprint Severe lumbar retrospondylolisthesis associated with hemodialysis in a patient with chronic renal failure: a case report
    Gen Arai
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chuo Ku, Japan
    J Orthop Sci 10:418-21. 2005
  25. doi request reprint Teriparatide accelerates lumbar posterolateral fusion in women with postmenopausal osteoporosis: prospective study
    Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, Japan
    Spine (Phila Pa 1976) 37:E1464-8. 2012
    ..Prospective trial...
  26. doi request reprint Evaluation of low back pain using the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire for lumbar spinal disease in a multicenter study: differences in scores based on age, sex, and type of disease
    Seiji Ohtori
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo Ku, Chiba, Japan
    J Orthop Sci 15:86-91. 2010
    ....
  27. ncbi request reprint Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents
    Yasuchika Aoki
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 30:1496-500. 2005
    ..The expression of vanilloid receptor 1 (VR1), calcitonin gene-related peptide (CGRP), and isolectin B4 (IB4)-binding glycoprotein in dorsal root ganglion (DRG) neurons innervating the lumbar disc and the plantar skin was investigated...
  28. ncbi request reprint Insertional torque of the lumbar pedicle screw during surgery
    Tomoyuki Ozawa
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba, 260 8677, Japan
    J Orthop Sci 10:133-6. 2005
    ..This study demonstrated that intraoperative insertional torque is not an objective predictor of screw loosening or clinical results...
  29. pmc Characteristics of sensory DRG neurons innervating the lumbar facet joints in rats
    Tetsuhiro Ishikawa
    Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Eur Spine J 14:559-64. 2005
    ..Most neurons transmitting pain are CGRP-IR peptide-containing neurons. They may have a more significant role in pain sensation in the facets via peptidergic DRG neurons...
  30. ncbi request reprint Disc inflammation potentially promotes axonal regeneration of dorsal root ganglion neurons innervating lumbar intervertebral disc in rats
    Yasuchika Aoki
    Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
    Spine (Phila Pa 1976) 29:2621-6. 2004
    ....
  31. ncbi request reprint Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats
    Makoto Otsuka
    Faculty of Pharmacy, Research Institute of Pharmaceutical Sciences, Musashino University, Shinmachi 1 1 20, Nishi Tokyo 202 8585, Japan
    J Pharm Sci 97:421-32. 2008
    ..Results indicate that the new injectable CaP formulations are effective in improving bone properties of OVX rats and may be useful in osteoporosis therapy...
  32. ncbi request reprint Effect of controlled zinc release on bone mineral density from injectable Zn-containing beta-tricalcium phosphate suspension in zinc-deficient diseased rats
    Makoto Otsuka
    Kobe Pharmaceutical University, Department of Pharmaceutical Technology, Motoyama Kitamachi 4 19 1, Higashi Nada, Kobe 658 8558, Japan
    J Biomed Mater Res A 69:552-60. 2004
    ..The results of this study suggest that the local effect on BMD was more pronounced than the effect on the whole body...
  33. ncbi request reprint Effect of particle size on zinc release from zinc containing tricalcium phosphate (ZnTCP) in Zn-deficient osteoporosis rats
    Makoto Otsuka
    Kobe Pharmaceutical University, Motoyama Kitamachi, Higashi Nada, Kobe 658 8558, Japan
    Biomed Mater Eng 13:103-13. 2003
    ..In contrast, the AIP for the control decreased after 2 days. The area under the curve of the AIP (AIP-AUC) for 6 days of S-ZnTCP was significantly higher than that of other groups...
  34. ncbi request reprint Therapeutic effect of in vivo sustained estradiol release from poly (lactide-co-glycolide) microspheres on bone mineral density of osteoporosis rats
    Makoto Otsuka
    Department of Pharmaceutical Technology, Kobe Pharmaceutical University, Motoyama Kitamachi 4 19 1, Higashi Nada, Kobe 658 8558, Japan
    Biomed Mater Eng 12:157-67. 2002
    ..This suggested that all estradiol microspheres administration induced bone generation in osteoporosis rats...