Genotyping of Haemophilus influenzae type b in pre-vaccination eraTaketo Otsuka
Department of Pediatrics, Sado General Hospital, 113 1, Chigusa, Sado, Niigata 952 1209, Japan
J Infect Chemother 18:213-8. 2012
..The ST54 and ST190 strains circulated in Sado Island and were detected in both asymptomatic carriers and patients. We note that surveillance of healthy subjects to identify Hib carriers is important to understand the transmission of Hib...
Influenza vaccination for severely multiply handicapped persons/children in the 2005-2006 seasonTaketo Otsuka
Department of Pediatrics, Niigata National Hospital, 3 52, Akasaka Cho, Kashiwazaki, Niigata 945 8585, Japan
Vaccine 25:4521-4. 2007
..These data suggest that it might be difficult for SMHPs (including potential responders) to achieve the priming effect by the current TIV. Consequently, they cannot obtain a booster effect...
- Influenza vaccination in severely multiply handicapped persons/children
Taketo Otsuka
Department of Pediatrics, Niigata National Hospital, 3 52, Akasaka Cho, Kashiwazaki, Niigata 945 8585, Japan
Vaccine 24:4096-101. 2006
..However, the effectiveness for severely multiply handicapped persons/children (SMHPs) is not yet well established...
- Resistance of nasopharyngeal pathogens and antimicrobial prescription rates for children in an area under controlled antimicrobial use
Taketo Otsuka
Department of Pediatrics, Sado General Hospital, Niigata, Japan
Pediatr Infect Dis J 28:128-30. 2009
..To reduce the spread of drug-resistant pathogens, appropriate use of antimicrobials is an indispensable measure. From January 2002, we undertook campaigns about antimicrobial treatment in Sado Island, Japan...
- Molecular characterization of methicillin-resistant Staphylococcus aureus in hospitals in Niigata, Japan: divergence and transmission
Hassan Zaraket
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Microbiol Immunol 51:171-6. 2007
..The data suggest that MRSA in hospitals in Niigata now mainly includes the New York/Japan clone (undergoing genomic divergence and clonal expansion) and other minor types (e.g. ST8) as well as the community type...
- A rapid screening method for Panton-Valentine leucocidin-positive community-acquired methicillin-resistant Staphylococcus aureus belonging to multilocus sequence type 30 and its related clone using a combination of multiplex PCR and pulsed-field gel elect
Ivan Reva
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata, 951 8510, Japan
J Infect Chemother 15:75-83. 2009
..aureus, or coagulase-negative staphylococci (CNS), including MRCNS. This screening method is more useful than genotyping for routine work in many clinical laboratories...
Novel characteristics of community-acquired methicillin-resistant Staphylococcus aureus strains belonging to multilocus sequence type 59 in TaiwanTomomi Takano
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata, Japan
Antimicrob Agents Chemother 52:837-45. 2008
....
- Key adhesin gene in community-acquired methicillin-resistant Staphylococcus aureus
Taketo Otsuka
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Biochem Biophys Res Commun 346:1234-44. 2006
..Thus, the pandemic type is characterized by the combination of luk(PV) and bbp (and cna) genes. A specific real-time PCR assay for the bbp gene was developed, and dual assay for bbp and luk(PV) in one test tube became possible...
- Prevalence of methicillin-resistant Staphylococcus aureus among children in a region with controlled antimicrobial use
Taketo Otsuka
Department of Pediatrics, Sado General Hospital, Niigata 952 1209, Japan ootsukataketo hotmail com
Jpn J Infect Dis 64:436-8. 2011
..3% versus 28.5%; P < 0.05). In conclusion, prevalence of MRSA in children in our study population could be decreased by eliminating unnecessary antimicrobial drug prescriptions...
- Molecular epidemiology of methicillin-resistant Staphylococcus aureus isolated from children in a community with low antimicrobial pressure in Japan
Taketo Otsuka
Department of Pediatrics, Sado General Hospital, Niigata, Japan ootsukataketo hotmail com
Jpn J Infect Dis 65:483-8. 2012
..In this study, we have shown that multiple MRSA strains can circulate in a community even under low antimicrobial pressure...
- [Colonization and transmission of Haemophilus influenzae type b (Hib)]
Taketo Otsuka
Department of Pediatrics, Sado General Hospital
Kansenshogaku Zasshi 86:103-8. 2012
..2%). These data suggested that each ST strain may be brought into Sado Island by different routes. We note that surveillance of healthy subjects to identify Hib carriers is important to understand their role in transmission of Hib...
- Duplication of chromosome 4q: renal pathology of two siblings
Taketo Otsuka
Department of Pediatrics, Niigata National Hospital, Niigata, Japan
Am J Med Genet A 134:330-3. 2005
..We suggest that renal hypoplasia may be female-prone, and may have a close relationship with duplication of 4q33-q34...
- Molecular nature of methicillin-resistant Staphylococcus aureus derived from explosive nosocomial outbreaks of the 1980s in Japan
Ikue Taneike
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 1-757, Asahimachi-dori, Niigata, Japan
FEBS Lett 580:2323-34. 2006
..aureus ST30, was highly adhesive (carrying cna and bbp genes), highly-toxic (carrying luk(PV) and sea genes) and highly drug-resistant. PVL(+) HA-MRSA was once replaced by other PVL(-) HA-MRSA (e.g., ST5), and is re-emerging as CA-MRSA...
- Pediatric pneumonia death caused by community-acquired methicillin-resistant Staphylococcus aureus, Japan
Takashi Ito
Emerg Infect Dis 14:1312-4. 2008
