Rachel M Ostroff
- Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance toolRachel M Ostroff
Clinical Research, SomaLogic Inc, Boulder, Colorado, United States of America
PLoS ONE 7:e46091. 2012..To improve surveillance and detection of MM in the high-risk population, we completed a series of clinical studies to develop a noninvasive test for early detection...
- Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancerRachel M Ostroff
SomaLogic, Boulder, Colorado, United States of America
PLoS ONE 5:e15003. 2010..Here we present a comprehensive clinical biomarker study of lung cancer and the first large-scale clinical application of a new aptamer-based proteomic technology to discover blood protein biomarkers in disease...
- Protein signature of lung cancer tissuesMichael R Mehan
SomaLogic, Inc, Boulder, Colorado, United States of America
PLoS ONE 7:e35157. 2012..The combined results from tissue and serum present the most extensive view to date of the complex changes in NSCLC protein expression and provide important implications for diagnosis and treatment...
- Aptamer-based multiplexed proteomic technology for biomarker discoveryLarry Gold
SomaLogic, Boulder, Colorado, USA
PLoS ONE 5:e15004. 2010..The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine...