Lars Ostergaard

Summary

Publications

  1. pmc Risk of human papillomavirus-related cancers among kidney transplant recipients and patients receiving chronic dialysis--an observational cohort study
    Lars Skov Dalgaard
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    BMC Nephrol 14:137. 2013
  2. ncbi request reprint Persistence of antibodies for 42 months following vaccination of adolescents with a meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine (MenACWY-TT)
    Lars Østergaard
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgårdsvej 100, 8200 Aarhus N, Denmark
    Int J Infect Dis 17:e173-6. 2013
  3. doi request reprint A tetravalent meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine is immunogenic and well-tolerated when co-administered with Twinrix(®) in subjects aged 11-17 years: an open, randomised, controlled trial
    Lars Østergaard
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, 8200 Aarhus N, Denmark
    Vaccine 30:774-83. 2012
  4. pmc Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy
    Thomas A Rasmussen
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    BMC Infect Dis 11:267. 2011
  5. pmc Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models
    Martin Tolstrup
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej 100, 8200 Aarhus, Denmark
    BMC Immunol 14:51. 2013
  6. doi request reprint Central nervous system infections among individuals with and without end-stage renal disease
    Jesper D Gunst
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus N, Denmark
    J Infect 67:19-26. 2013
  7. pmc T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication
    Randi K Berg
    Department of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark
    PLoS ONE 9:e84513. 2014
  8. ncbi request reprint Disclosure decisions: HIV-positive persons coping with disease-related stressors
    Lotte Rodkjaer
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    Qual Health Res 21:1249-59. 2011
  9. pmc Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals
    Anne Roslev Bukh
    Department of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark
    PLoS ONE 6:e21275. 2011
  10. doi request reprint Risk and prognosis of hospitalization for pneumonia among individuals with and without functioning renal transplants in Denmark: a population-based study
    Lise H Nielsen
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardvej 100, Aarhus 8200, Denmark
    Clin Infect Dis 55:679-86. 2012

Collaborators

Detail Information

Publications23

  1. pmc Risk of human papillomavirus-related cancers among kidney transplant recipients and patients receiving chronic dialysis--an observational cohort study
    Lars Skov Dalgaard
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    BMC Nephrol 14:137. 2013
    ..Individuals with end-stage renal disease (ESRD) have excess risk of various cancer types. However, the total burden of human papillomavirus-related cancers remains unknown...
  2. ncbi request reprint Persistence of antibodies for 42 months following vaccination of adolescents with a meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine (MenACWY-TT)
    Lars Østergaard
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgårdsvej 100, 8200 Aarhus N, Denmark
    Int J Infect Dis 17:e173-6. 2013
    ..This study assessed antibody persistence at 3.5 years after vaccination with a MenACWY-TT or a tetravalent ACWY polysaccharide vaccine (MenPS, control)...
  3. doi request reprint A tetravalent meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine is immunogenic and well-tolerated when co-administered with Twinrix(®) in subjects aged 11-17 years: an open, randomised, controlled trial
    Lars Østergaard
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, 8200 Aarhus N, Denmark
    Vaccine 30:774-83. 2012
    ..This study suggests that MenACWY-TT vaccine could be co-administered with HepA/B without adversely impacting the immunogenicity, safety and reactogenicity of either of the vaccines...
  4. pmc Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy
    Thomas A Rasmussen
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    BMC Infect Dis 11:267. 2011
    ..Our objective was to evaluate and compare the effect of abacavir on levels of biomarkers associated with cardiovascular risk...
  5. pmc Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models
    Martin Tolstrup
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej 100, 8200 Aarhus, Denmark
    BMC Immunol 14:51. 2013
    ..Here we test the hypothesis that such immunosuppressive peptides may serve as immunomodulatory reagents for treatment of inflammatory disorders...
  6. doi request reprint Central nervous system infections among individuals with and without end-stage renal disease
    Jesper D Gunst
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus N, Denmark
    J Infect 67:19-26. 2013
    ..Individuals with immunodeficiencies are at increased risk of central nervous system (CNS) infections. Data are limited on the risk of CNS infections in patients with end-stage renal disease (ESRD)...
  7. pmc T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication
    Randi K Berg
    Department of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark
    PLoS ONE 9:e84513. 2014
    ..This phenomenon could contribute to the high permissiveness of CD4+ T cells for HIV-1. ..
  8. ncbi request reprint Disclosure decisions: HIV-positive persons coping with disease-related stressors
    Lotte Rodkjaer
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    Qual Health Res 21:1249-59. 2011
    ....
  9. pmc Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals
    Anne Roslev Bukh
    Department of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark
    PLoS ONE 6:e21275. 2011
    ..Microbial translocation may contribute to the immunopathogenesis in HIV infection. We investigated if microbial translocation and inflammation were associated with innate and adaptive immune responses in adults with HIV...
  10. doi request reprint Risk and prognosis of hospitalization for pneumonia among individuals with and without functioning renal transplants in Denmark: a population-based study
    Lise H Nielsen
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardvej 100, Aarhus 8200, Denmark
    Clin Infect Dis 55:679-86. 2012
    ..Pneumonia is commonly diagnosed in immunosuppressed individuals. The risk and attributable morbidity of first hospitalization for pneumonia among renal transplant candidates and recipients were compared to those of population controls...
  11. pmc Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles
    Tea Kirkegaard
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, DK 8200 Aarhus N, Denmark
    Virol J 8:381. 2011
    ..Lastly, we identified stronger IgG2a class switching in the two particle-delivered antigen vaccinations modalities compared to recombinant gp160...
  12. doi request reprint Changes in depression in a cohort of Danish HIV-positive individuals: time for routine screening
    Lotte Rodkjaer
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, DK 8200 Aarhus N, Denmark
    Sex Health 8:214-21. 2011
    ..The aim of this study was to follow a cohort of HIV-positive individuals for 3 years in order to assess changes in depression, adherence, unsafe sex and emotional strains from living with HIV...
  13. ncbi request reprint HIV late presenters in Denmark: need for increased diagnostic awareness among general practitioners
    Peter Derek Christian Leutscher
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    Dan Med Bull 58:A4253. 2011
    ..The study objective was to describe demographic and clinical characteristics among HIV late presenters in a Danish university hospital...
  14. ncbi request reprint Pneumococcal conjugate vaccination in persons with HIV: the effect of highly active antiretroviral therapy
    Ole S Søgaard
    Department of Infectious Diseases, Aarhus University Hospital, Denmark
    AIDS 24:1315-22. 2010
    ..We aimed to determine HAART's impact on seven-valent pneumococcal conjugate (7vPnC) vaccine immunization with or without a Toll-like receptor 9 (TLR9) agonist adjuvant...
  15. pmc HSV-1-induced chemokine expression via IFI16-dependent and IFI16-independent pathways in human monocyte-derived macrophages
    Stine Søby
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej 100, Aarhus N, DK 8200, Denmark
    Herpesviridae 3:6. 2012
    ..abstract:..
  16. pmc Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: a Danish historical cohort study
    Sanne Jespersen
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Brendstrupgaardsvej 100, 8200 Aarhus N, Denmark
    BMC Infect Dis 10:124. 2010
    ..Community-acquired [CAL] and hospital-acquired legionellosis [HAL] may have different presentations and outcome. We aimed to compare clinical characteristics and examine predictors of mortality for CAL and HAL...
  17. ncbi request reprint Hepatitis B and Delta Virus Are Prevalent but Often Subclinical Co-Infections among HIV Infected Patients in Guinea-Bissau, West Africa: A Cross-Sectional Study
    Bo Langhoff Hønge
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark
    PLoS ONE 9:e99971. 2014
    ..Co or super-infection with hepatitis Delta virus (HDV) may worsen the liver disease and complicate treatment possibilities...
  18. ncbi request reprint Performance of 3 rapid tests for discrimination between HIV-1 and HIV-2 in Guinea-Bissau, West Africa
    Bo Langhoff Hønge
    Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau National HIV Programme, Ministry of Health, Bissau, Guinea Bissau National Public Health Laboratory, Bissau, Guinea Bissau GloHAU, Center for Global Health, School of Public Health, Aarhus University, Aarhus, Denmark and Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
    J Acquir Immune Defic Syndr 65:87-90. 2014
    ..8%), followed by Immunoflow HIV1-HIV2 (agreement 90.9%) and SD Bioline HIV-1/2 3.0 (agreement 84.5%). Our results underscore the need for evaluation of tests in relevant populations before implementation...
  19. doi request reprint Reproductive patterns and fertility wishes among HIV-infected patients: survey from six outpatient clinics in Denmark
    Tinne Laursen
    Department of Infectious Diseases, Aarhus University Hospital, Brendstrupgaardsvej, Skejby, 8200 Aarhus N, Denmark
    Int J Infect Dis 17:e851-6. 2013
    ..Reproductive patterns among HIV patients in Denmark have not previously been described. We aimed to uncover the fertility wishes among Danish HIV-infected persons...
  20. pmc Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA
    Randi K Berg
    Department of Infectious Diseases, Aarhus University Hospital Skejby, Aarhus, Denmark
    PLoS ONE 7:e29291. 2012
    ..However, knowledge on specific HIV PAMPs and cellular PRRs responsible for inducing innate immune responses remains sparse...
  21. doi request reprint Transmission of HIV-1 drug-resistant variants: prevalence and effect on treatment outcome
    Martin R Jakobsen
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    Clin Infect Dis 50:566-73. 2010
    ....
  22. doi request reprint Combined assay for two-hour identification of Streptococcus pneumoniae and Neisseria meningitidis and concomitant detection of 16S ribosomal DNA in cerebrospinal fluid by real-time PCR
    Susanna Deutch
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    Scand J Infect Dis 40:607-14. 2008
    ..1%) patients, respectively. In conclusion, the combined real-time PCR strategy is superior to microscopy and a valuable supplement to routine culture to establish the aetiology of bacterial meningitis...
  23. doi request reprint Immunogenicity, reactogenicity and persistence of meningococcal A, C, W-135 and Y-tetanus toxoid candidate conjugate (MenACWY-TT) vaccine formulations in adolescents aged 15-25 years
    Lars Ostergaard
    Department of Infectious Diseases, Aarhus University Hospital, Denmark
    Vaccine 27:161-8. 2009
    ..Our results present five investigational MenACWY-TT conjugate vaccine formulations which are well tolerated and highly immunogenic in adolescents...