Attempting to explain heterogeneous HIV epidemics in sub-Saharan Africa: potential role of historical changes in risk behaviour and male circumcisionKate K Orroth
Epidemiology and Public Heath, London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Infect 87:640-5. 2011
..They also investigate the effects of different prevalence of male circumcision on the HIV epidemics in the four cities...
Understanding the differences between contrasting HIV epidemics in east and west Africa: results from a simulation model of the Four Cities StudyKate K Orroth
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Sex Transm Infect 83:i5-16. 2007
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- Male circumcision for HIV prevention in sub-Saharan Africa: who, what and when?
Richard G White
London School of Hygiene and Tropical Medicine, London, UK
AIDS 22:1841-50. 2008
..We explore how the population-level impact of circumcision varies by target age group, coverage, time-to-scale-up, level of risk compensation and circumcision of HIV infected men...
- Treating curable sexually transmitted infections to prevent HIV in Africa: still an effective control strategy?
Richard G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
J Acquir Immune Defic Syndr 47:346-53. 2008
..We explore whether treating curable STIs remains a cost-effective HIV control strategy in Africa...
- Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/sexually transmitted disease intervention trials?: A modeling study
Richard G White
London School of Hygiene and Tropical Medicine, London, UK
J Acquir Immune Defic Syndr 37:1500-13. 2004
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- Empirical observations underestimate the proportion of human immunodeficiency virus infections attributable to sexually transmitted diseases in the Mwanza and Rakai sexually transmitted disease treatment trials: Simulation results
Kate K Orroth
London School of Hygiene and Tropical Medicine, London, UK
Sex Transm Dis 33:536-44. 2006
..Empirical PAF estimates from the Mwanza and Rakai trials indicated the proportion of HIV infections attributable to STDs was higher in Mwanza than Rakai...
Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan AfricaEsther E Freeman
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK
Vaccine 27:940-6. 2009
..Over 20 years, in most scenarios fewer than 100 vaccinations were required to avert one HIV infection. HSV2 vaccines could have a substantial impact on HIV incidence. Intensified efforts are needed to develop an effective HSV2 vaccine...
- Quantifying HIV-1 transmission due to contaminated injections
Richard G White
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
Proc Natl Acad Sci U S A 104:9794-9. 2007
..This result is likely to be generalizable to many other populations in sub-Saharan Africa...
- Higher risk behaviour and rates of sexually transmitted diseases in Mwanza compared to Uganda may help explain HIV prevention trial outcomes
Kate K Orroth
London School of Hygiene and Tropical Medicine, London, UK
AIDS 17:2653-60. 2003
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- Proportion of new HIV infections attributable to herpes simplex 2 increases over time: simulations of the changing role of sexually transmitted infections in sub-Saharan African HIV epidemics
Esther E Freeman
Harvard Medical School, Francis Weld Peabody Society, 260 Longwood Ave, Boston, MA 02115, USA
Sex Transm Infect 83:i17-24. 2007
..To understand the changing impact of herpes simplex 2 (HSV-2) and other sexually transmitted infections (STIs) on HIV incidence over time in four sub-Saharan African cities, using simulation models...
