H H Berendsen

Summary

Affiliation: Organon Laboratories Ltd

Publications

  1. ncbi request reprint Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 133:275-82. 1997
  2. ncbi request reprint Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, Netherlands
    Eur Neuropsychopharmacol 9:345-9. 1999
  3. ncbi request reprint Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine
    C L Broekkamp
    Department CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Naunyn Schmiedebergs Arch Pharmacol 338:191-5. 1988
  4. ncbi request reprint Mirtazapine enhances the effect of haloperidol on apomorphine-induced climbing behaviour in mice and attenuates haloperidol-induced catalepsy in rats
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 135:284-9. 1998
  5. ncbi request reprint A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats
    H H Berendsen
    Department of CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Eur J Pharmacol 194:201-8. 1991
  6. ncbi request reprint The role of serotonin in hot flushes
    H H Berendsen
    Pharmacology Department, N V Organon, POB 20, 5340 BH, Oss, Netherlands
    Maturitas 36:155-64. 2000

Collaborators

  • C L Broekkamp
  • A M Van Delft
  • S K Oosterloo

Detail Information

Publications6

  1. ncbi request reprint Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 133:275-82. 1997
    ..1-1.0 mg/kg). On the basis of these results, it can be concluded that mirtazapine has indirect 5-HT1A receptor agonistic properties which may play an important role in the therapeutic effect of this compound...
  2. ncbi request reprint Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, Netherlands
    Eur Neuropsychopharmacol 9:345-9. 1999
    ..The results also indicate that the conditioned taste aversion paradigm can be used to test for antagonism of stimulus properties of compounds...
  3. ncbi request reprint Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine
    C L Broekkamp
    Department CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Naunyn Schmiedebergs Arch Pharmacol 338:191-5. 1988
    ..The antagonistic effect of 8-OHDPAT suggests a secondary, modulating role for 5-HT1A receptor mediated events in both types of catalepsy...
  4. ncbi request reprint Mirtazapine enhances the effect of haloperidol on apomorphine-induced climbing behaviour in mice and attenuates haloperidol-induced catalepsy in rats
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 135:284-9. 1998
    ..The results obtained in these experiments suggest that co-treatment with mirtazapine may enhance the antipsychotic effect of haloperidol and reduce its extrapyramidal side effects, thereby widening its therapeutic window...
  5. ncbi request reprint A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats
    H H Berendsen
    Department of CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Eur J Pharmacol 194:201-8. 1991
    ..Hindlimb scratching was not induced by i.c.v. injection of 5-MeOT.(ABSTRACT TRUNCATED AT 250 WORDS)..
  6. ncbi request reprint The role of serotonin in hot flushes
    H H Berendsen
    Pharmacology Department, N V Organon, POB 20, 5340 BH, Oss, Netherlands
    Maturitas 36:155-64. 2000
    ..Especially the 5-HT(2A) receptor subtype may play a key role in the occurrence of hot flushes. A number of arguments that support this hypothesis are discussed...