H H Berendsen

Summary

Affiliation: Organon Laboratories Ltd

Publications

  1. ncbi request reprint Mirtazapine enhances the effect of haloperidol on apomorphine-induced climbing behaviour in mice and attenuates haloperidol-induced catalepsy in rats
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 135:284-9. 1998
  2. ncbi request reprint Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, Netherlands
    Eur Neuropsychopharmacol 9:345-9. 1999
  3. ncbi request reprint The role of serotonin in hot flushes
    H H Berendsen
    Pharmacology Department, N V Organon, POB 20, 5340 BH, Oss, Netherlands
    Maturitas 36:155-64. 2000
  4. ncbi request reprint Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats
    H H Berendsen
    Pharmacology Department, NV Organon, P O Box 20, 5340 BH, Oss, Netherlands
    Eur J Pharmacol 419:47-54. 2001
  5. ncbi request reprint Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 133:275-82. 1997
  6. ncbi request reprint Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine
    C L Broekkamp
    Department CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Naunyn Schmiedebergs Arch Pharmacol 338:191-5. 1988
  7. ncbi request reprint A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats
    H H Berendsen
    Department of CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Eur J Pharmacol 194:201-8. 1991

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Mirtazapine enhances the effect of haloperidol on apomorphine-induced climbing behaviour in mice and attenuates haloperidol-induced catalepsy in rats
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 135:284-9. 1998
    ..The results obtained in these experiments suggest that co-treatment with mirtazapine may enhance the antipsychotic effect of haloperidol and reduce its extrapyramidal side effects, thereby widening its therapeutic window...
  2. ncbi request reprint Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, Netherlands
    Eur Neuropsychopharmacol 9:345-9. 1999
    ..The results also indicate that the conditioned taste aversion paradigm can be used to test for antagonism of stimulus properties of compounds...
  3. ncbi request reprint The role of serotonin in hot flushes
    H H Berendsen
    Pharmacology Department, N V Organon, POB 20, 5340 BH, Oss, Netherlands
    Maturitas 36:155-64. 2000
    ..Especially the 5-HT(2A) receptor subtype may play a key role in the occurrence of hot flushes. A number of arguments that support this hypothesis are discussed...
  4. ncbi request reprint Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats
    H H Berendsen
    Pharmacology Department, NV Organon, P O Box 20, 5340 BH, Oss, Netherlands
    Eur J Pharmacol 419:47-54. 2001
    ..This method of measuring tail temperature free of stress in ovariectomised rats may serve as a useful procedure for selecting compounds that are of potential use in the treatment of hot flushes...
  5. ncbi request reprint Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine
    H H Berendsen
    Department of Neuropharmacology, N V Organon, Oss, The Netherlands
    Psychopharmacology (Berl) 133:275-82. 1997
    ..1-1.0 mg/kg). On the basis of these results, it can be concluded that mirtazapine has indirect 5-HT1A receptor agonistic properties which may play an important role in the therapeutic effect of this compound...
  6. ncbi request reprint Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine
    C L Broekkamp
    Department CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Naunyn Schmiedebergs Arch Pharmacol 338:191-5. 1988
    ..The antagonistic effect of 8-OHDPAT suggests a secondary, modulating role for 5-HT1A receptor mediated events in both types of catalepsy...
  7. ncbi request reprint A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats
    H H Berendsen
    Department of CNS Pharmacology, Organon International B V, Oss, The Netherlands
    Eur J Pharmacol 194:201-8. 1991
    ..Hindlimb scratching was not induced by i.c.v. injection of 5-MeOT.(ABSTRACT TRUNCATED AT 250 WORDS)..