Association between ABCB1 polymorphism and response to sodium valproate treatment in Malaysian epilepsy patientsBatoul Sadat Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Epileptic Disord 13:65-75. 2011
..Our data suggest that C1236T, G2677T/A, and C3435T polymorphisms in the ABCB1 gene do not contribute to the response to VPA in patients with epilepsy...
SCN1A IVS5N+5 polymorphism and response to sodium valproate: a multicenter studyBatoul Sadat Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, University of Malaya, Kuala Lumpur, Malaysia
Pharmacogenomics 13:1477-85. 2012
..The purpose of this study was to examine this hypothesis in a cohort study of Malaysian and Hong Kong Chinese epilepsy patients on sodium valproate (VPA) monotherapy and in a meta-analysis...
GABRG2 rs211037 polymorphism and epilepsy: a systematic review and meta-analysisBatoul Sadat Haerian
Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Seizure 22:53-8. 2013
..We therefore performed a systematic review and meta-analysis to examine whether this polymorphism is associated with FS or IGE...
ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysisB S Haerian
Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Seizure 19:339-46. 2010
..To assess the role of C3435T polymorphism in drug-resistance in epilepsy, a systematic review and meta-analysis was conducted...
Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsyB S Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Seizure 20:387-94. 2011
..Our data showed that these polymorphisms may not contribute to the response to CBZ or VPA monotherapy treatment in epilepsy...
Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysisBatoul Sadat Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Pharmacogenomics 12:713-25. 2011
..Here, we performed the first haplotype meta-analysis to examine the association of haplotypes of ABCB1 common variants with the response to treatment in epilepsy...
Lack of association between synapsin II (SYN2) gene polymorphism and susceptibility epilepsy: a case-control study and meta-analysisBatoul Sadat Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Synapse 65:1073-9. 2011
..The aim of this study was to investigate the association between the SYN2 rs3773364 A>G polymorphism and susceptibility against epilepsy in a case-control study and a meta-analysis...
Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsyB S Haerian
Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Seizure 20:546-53. 2011
..Our findings suggest that the ABCB1 rs3789243 C>T, C1236T, G2677T/A, rs6949448 C>T, and C3435T haplotypes do not contribute to response to AED treatment in epilepsy...