Functional anatomy of musical perception in musiciansT Ohnishi
Department of Radiology and Psychiatry, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira City, Tokyo 187 8551, Japan
Cereb Cortex 11:754-60. 2001
..We suggest that such activity is associated with absolute pitch ability and the use-dependent functional reorganization produced by the early commencement of long-term training...
Lin4Neuro: a customized Linux distribution ready for neuroimaging analysisKiyotaka Nemoto
Department of Psychiatry, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
BMC Med Imaging 11:3. 2011
..We developed a live USB-bootable Linux package named "Lin4Neuro." This system includes popular neuroimaging analysis tools. The user interface is customized so that even Windows users can use it intuitively...
- Abnormal regional cerebral blood flow in childhood autism
T Ohnishi
Department of Radiology, National Center Hospital of Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira City, Tokyo, Japan
Brain 123:1838-44. 2000
..The perfusion patterns suggest possible locations of abnormalities of brain function underlying abnormal behaviour patterns in autistic individuals...
- The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia
Takashi Ohnishi
Department of Radiology, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira City, Tokyo, Japan
Brain 129:399-410. 2006
..Our findings suggest that the Val158Met polymorphism of the COMT gene might contribute to morphological abnormalities in schizophrenia...
- Navigation ability dependent neural activation in the human brain: an fMRI study
Takashi Ohnishi
Department of Radiology, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawa Higashi, Kodaira City, Tokyo 187 8551, Japan
Neurosci Res 55:361-9. 2006
..Our data suggest that different brain activities related to navigation should reflect navigation skill and strategies...
- The neural network for the mirror system and mentalizing in normally developed children: an fMRI study
Takashi Ohnishi
Department of Radiology, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawa Higashi, Kodaira City, Tokyo 187 8551, Japan
Neuroreport 15:1483-7. 2004
..We suggest that mentalizing might evolve from a capacity to detect the motion of agents and to infer intentions. Further, mentalizing might require self-perspectives...
- Correction for partial-volume effects on brain perfusion SPECT in healthy men
Hiroshi Matsuda
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi, Kodaira, 187 8551 Tokyo, Japan
J Nucl Med 44:1243-52. 2003
..The aim of this study was to determine which brain structures show greater influence of PVEs in SPECT studies on healthy volunteers and to investigate aging effects on SPECT after the PVE correction...
- Gender difference in brain perfusion 99mTc-ECD SPECT in aged healthy volunteers after correction for partial volume effects
Zhi-Jie Li
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan
Nucl Med Commun 25:999-1005. 2004
..The PVE correction of SPECT images revealed gender differences that were consistent with the universal findings of better performance on verbal tasks in women and on visuospatial tasks in men...
- Empathy and judging other's pain: an fMRI study of alexithymia
Yoshiya Moriguchi
Department of Psychosomatic Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira City, Tokyo 187 8553, Japan
Cereb Cortex 17:2223-34. 2007
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- rCBF changes elicited by rTMS over DLPFC in humans
Takashi Ohnishi
Department of Radiology, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4-1-1 Ogawa Higashi, Kodaira City, Tokyo 187-8551, Japan
Suppl Clin Neurophysiol 57:715-20. 2004
..We conclude that the lasting effect on the ventral striatum should reflect modulatory effects of rTMS over the DLPFC on the meso-limbic dopaminergic system that must play critical roles in antidepressant effects...
The human mirror neuron system in a population with deficient self-awareness: an fMRI study in alexithymiaYoshiya Moriguchi
Department of Psychosomatic Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira City, Tokyo, Japan
Hum Brain Mapp 30:2063-76. 2009
..These results suggest that the stronger MNS-related neural response in individuals scoring high on ALEX is associated with their insufficient self-other differentiation...
- Progressive changes of white matter integrity in schizophrenia revealed by diffusion tensor imaging
Takeyuki Mori
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawa Higashi, Kodaira City, Tokyo, 187 8551, Japan
Psychiatry Res 154:133-45. 2007
..Our data confirmed decreased FA in schizophrenics, compared to controls in the widespread WM areas. Such decreased FA values in schizophrenia might be attributable, at least in part, to progressive changes after the onset of the illness...
- The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT
Kentaro Hirao
Department of Radiology, National Center Hospital of Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan
Neuroimage 28:1014-21. 2005
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- Superiority of 3-dimensional stereotactic surface projection analysis over visual inspection in discrimination of patients with very early Alzheimer's disease from controls using brain perfusion SPECT
Etsuko Imabayashi
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan
J Nucl Med 45:1450-7. 2004
..It is clinically useful and reliable to adopt the use of 3D-SSP as an adjunct to visual interpretation...
- Functional interactions between entorhinal cortex and posterior cingulate cortex at the very early stage of Alzheimer's disease using brain perfusion single-photon emission computed tomography
Kentaro Hirao
Department of Radiology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan
Nucl Med Commun 27:151-6. 2006
..CONCLUSION: These results indicate that rCBF changes in the posterior cingulate cortex may be closely related to those in the entorhinal cortex in patients with Alzheimer's disease, thereby supporting the 'remote effect' hypothesis...
- Effects of partial volume correction on discrimination between very early Alzheimer's dementia and controls using brain perfusion SPECT
Hidekazu Kanetaka
Department of Radiology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Eur J Nucl Med Mol Imaging 31:975-80. 2004
..9% to 83.7% with global mean normalization. The PVC mildly enhanced the accuracy from 73.1% to 76.3% with cerebellar normalization. This result suggests that early diagnosis of AD requires PVC in a SPECT study...
- Impaired self-awareness and theory of mind: an fMRI study of mentalizing in alexithymia
Yoshiya Moriguchi
Department of Psychosomatic Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi Cho, Kodaira City, Tokyo 187-8553, Japan
Neuroimage 32:1472-82. 2006
..Thus, the skills involved in comprehending the self and others are inter-related and play an important role in emotion regulation...
- Apolipoprotein E genotype and early Alzheimer's disease: a longitudinal SPECT study
Shigeki Sakamoto
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi, Kodaira, 187 8551 Tokyo, Japan
J Neuroimaging 13:113-23. 2003
..To determine the association of the apolipoprotein E (APOE) genotype and longitudinal changes of regional cerebral blood flow (rCBF) in Alzheimer's disease (AD). Previous reports have yielded conflicting results concerning this association...
- The Val66Met polymorphism of the brain-derived neurotrophic factor gene affects age-related brain morphology
Kiyotaka Nemoto
Department of Radiology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1, Ogawahigashi, Kodaira, Tokyo 187 8551, Japan
Neurosci Lett 397:25-9. 2006
..Furthermore, we suggest that genotype effects of the BDNF gene on brain morphology might differ in female from in male...
- Differences in cerebral blood flow between missed and generalized seizures with electroconvulsive therapy: a positron emission tomographic study
Harumasa Takano
Department of Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi cho, Kodaira, Tokyo 187 8551, Japan
Epilepsy Res 97:225-8. 2011
..In contrast to missed seizures, rCBF was increased extensively, particularly in the centrencephalic structures in generalized seizures. These results further support the centrencephalic theory of seizure generalization...
- Voxel-based morphometry to discriminate early Alzheimer's disease from controls
Yoko Hirata
Department of Radiology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8551, Japan
Neurosci Lett 382:269-74. 2005
..8%. This result would open up a possibility for early diagnosis of AD using VBM...
- Changes of brain activity in the neural substrates for theory of mind during childhood and adolescence
Yoshiya Moriguchi
Department of Psychosomatic Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Japan
Psychiatry Clin Neurosci 61:355-63. 2007
..The authors consider that the age-related brain activity observed in the present study may be associated with the maturation of the prefrontal cortex and the associated development of cognitive functions...
- Brain SPET abnormalities in Alzheimer's disease before and after atrophy correction
Hiroshi Matsuda
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1, Ogawahigashi, Kodaira, 187 8551, Tokyo, Japan
Eur J Nucl Med Mol Imaging 29:1502-5. 2002
..This correction seems to be essential in order to achieve accurate measurements of rCBF in SPET, which has limited spatial resolution...
- A coil for magnetic stimulation of the macaque monkey brain
Yukio Nonaka
Neurology Division, Nihon Kohden Corporation, Tokyo, Japan
Suppl Clin Neurophysiol 56:75-80. 2003
- Stepping stone sampling for retrieving artifact-free electroencephalogram during functional magnetic resonance imaging
Kimitaka Anami
Department of Psychiatry, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo 187 8551, Japan
Neuroimage 19:281-95. 2003
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- Specific brain activation in Japanese and Caucasian people to fearful faces
Yoshiya Moriguchi
Department of Radiology, National Center Hospital of Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 1 7 3 Kouno dai, Ichikawa, Chiba 272 0827, Japan
Neuroreport 16:133-6. 2005
..The faces widely used as emotional stimuli therefore are not universally perceived, and cultural specificity should be taken into consideration in designing facial tasks...
- Mechanisms of unilateral STN-DBS in patients with Parkinson's disease : a PET study
Noritoshi Arai
Dept of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
J Neurol 255:1236-43. 2008
..These results suggest the mechanisms for bilateral improvement achieved by unilateral DBS...
- Abnormal cerebral glucose metabolism in alternating hemiplegia of childhood
Masayuki Sasaki
Department of Child Neurology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, 4 1 1 Ogawahigashi cho, Kodaira, Tokyo 187 8551, Japan
Brain Dev 31:20-6. 2009
..AHC might therefore result from focal abnormal glucose metabolism in the brain occurring progressively or permanently, particularly in the frontal lobes and the cerebellum...
- Neural mechanism of propofol anesthesia in severe depression: a positron emission tomographic study
Kenichi Ogawa
National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Anesthesiology 98:1101-11. 2003
..The authors examined the acute effects of propofol on regional cerebral blood flow (rCBF) using positron emission tomography in patients with severe depression...
- Effects of W-CDMA 1950 MHz EMF emitted by mobile phones on regional cerebral blood flow in humans
Yoko Mizuno
Department of Neurology, University of Tokyo, Tokyo, Japan
Bioelectromagnetics 30:536-44. 2009
..The subtraction analysis revealed no significant rCBF changes caused by the EMF conditions compared with the sham exposure, suggesting that EMF emitted by a third generation mobile phone does not affect rCBF in humans...
- Visual activation positron emission tomography for presurgical evaluation of occipital lobe epilepsy--case report
Hideyuki Nakama
Department of Neurosurgery, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo
Neurol Med Chir (Tokyo) 42:356-60. 2002
..Preoperative evaluation of the visual function in the epileptogenic occipital cortex by activation studies using PET or functional magnetic resonance imaging is the key to the successful surgical treatment of occipital lobe epilepsy...
- Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease
Hiroshi Matsuda
Department of Radiology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan
J Nucl Med 43:304-11. 2002
..The aim of this study was to determine the initial abnormality and the longitudinal changes in both morphologic and functional measurements for the same individuals with AD...
- Cerebral glucose metabolism associated with a fear network in panic disorder
Yojiro Sakai
Department of Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655
Neuroreport 16:927-31. 2005
..These results provided the first functional neuroimaging support in human patients for the neuroanatomical hypothesis of panic disorder focusing on the amygdala-based fear network...
- Effect of benzodiazepine hypnotic triazolam on relationship of blood pressure and Paco2 to cerebral blood flow during human non-rapid eye movement sleep
Masahiko Hiroki
Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan
J Neurophysiol 95:2293-303. 2006
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- Neural correlates for learning to read Roman numerals
Nobuo Masataka
Kyoto University, Inuyama, Aichi, Japan
Brain Lang 100:276-82. 2007
..Implications of these findings are argued with regard to the prevalent neuronal model for the implementation of elementary numerical abilities...
- Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling
Ryota Hashimoto
Osaka Hamamatsu Joint Research Center for Child Mental Development, Osaka University Graduate School of Medicine, D3, 2 2 Yamadaoka, 4 1 1 Suita, Osaka 565 0871, Japan
Hum Mol Genet 15:3024-33. 2006
..A possible biological mechanism of MDD might be implicated by these convergent data that Cys704 DISC1 is associated with the lower biological activity on ERK signaling, reduced brain gray matter volume and an increased risk for MDD...
- Changes in cerebral glucose utilization in patients with panic disorder treated with cognitive-behavioral therapy
Yojiro Sakai
Department of Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Tokyo 113 8655, Japan
Neuroimage 33:218-26. 2006
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- Effects of 1-Hz repetitive transcranial magnetic stimulation on acute pain induced by capsaicin
Yohei Tamura
Department of Neurology, Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo 105 8461, Japan
Pain 107:107-15. 2004
..We conclude that rTMS over M1 should have beneficial effects on acute pain, and its effects must be caused by functional changes of MPFC and caudal ACC...
- Neural correlates for numerical processing in the manual mode
Nobuo Masataka
Primate Research Institute, Kyoto University, Inuyama, Aichi 484 8506, Japan
J Deaf Stud Deaf Educ 11:144-52. 2006
..The similar neural network of brain regions responsible for numerical processing exists on a nonlinguistical basis and works to retrieve arithmetic facts from presented linguistic material regardless of the mode of the language...
