Fehmi Odabasoglu

Summary

Publications

  1. ncbi α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations
    Fehmi Odabasoglu
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, 25240 Erzurum, Turkey
    Br J Nutr 105:31-43. 2011
  2. ncbi Antioxidant activity, reducing power and total phenolic content of some lichen species
    F Odabasoglu
    Ataturk University, Faculty of Pharmacy, Department of Biochemistry, 25240 Erzurum, Turkey
    Fitoterapia 76:216-9. 2005
  3. ncbi Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats
    Fehmi Odabasoglu
    Ataturk University, Faculty of Pharmacy, Department of Biochemistry, Erzurum, Turkey
    J Ethnopharmacol 103:59-65. 2006
  4. ncbi The effects of methanol extract of Lobaria pulmonaria, a lichen species, on indometacin-induced gastric mucosal damage, oxidative stress and neutrophil infiltration
    Basak Karakus
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey
    Phytother Res 23:635-9. 2009
  5. ncbi Growth hormone reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
    Murat Yigiter
    Department of Pediatric Surgery, Ataturk University School of Medicine, Erzurum, Turkey
    Eur J Obstet Gynecol Reprod Biol 157:94-100. 2011
  6. ncbi The effects of diabetes and/or polymicrobial sepsis on the status of antioxidant enzymes and pro-inflammatory cytokines on heart, liver, and lung of ovariectomized rats
    Ayse Albayrak
    Department of Infection Disease, Education and Research Hospital, Erzurum, Turkey
    J Surg Res 169:67-75. 2011
  7. ncbi Evaluation of anti-inflammatory and antioxidant activities of Peltigera rufescens lichen species in acute and chronic inflammation models
    Sevil Tanas
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey
    J Nat Med 64:42-9. 2010
  8. ncbi The role of erythropoietin in the protection of gastric mucosa from indometacin-induced gastric injury and its relationship with oxidant and antioxidant parameters in rats
    Fatih Albayrak
    Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Ataturk University, Erzurum, Turkey
    J Pharm Pharmacol 62:85-90. 2010
  9. ncbi Atorvastatin reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
    Elif Cadirci
    Department of Pharmacology, Faculty of Pharmacy, Ataturk University, 25240 Erzurum, Turkey
    Naunyn Schmiedebergs Arch Pharmacol 381:455-66. 2010
  10. ncbi Beneficial effects of vegetable oils (corn, olive and sunflower oils) and alpha-tocopherol on anti-inflammatory and gastrointestinal profiles of indomethacin in rats
    Fehmi Odabasoglu
    Department of Biochemistry, Ataturk University, 25240, Erzurum, Turkey
    Eur J Pharmacol 591:300-6. 2008

Collaborators

Detail Information

Publications25

  1. ncbi α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations
    Fehmi Odabasoglu
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, 25240 Erzurum, Turkey
    Br J Nutr 105:31-43. 2011
    ..In conclusion, these results suggest that the anti-inflammatory properties of ALA, which has a strong anti-oxidative potency, could be related to its positive effects on the antioxidant system in a variety of tissues in rats...
  2. ncbi Antioxidant activity, reducing power and total phenolic content of some lichen species
    F Odabasoglu
    Ataturk University, Faculty of Pharmacy, Department of Biochemistry, 25240 Erzurum, Turkey
    Fitoterapia 76:216-9. 2005
    ..In contrast, there was a strong correlation between reducing power and total antioxidant activity of the extracts. The highest reducing power was determined for the methanol extract of P. rufescens...
  3. ncbi Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in rats
    Fehmi Odabasoglu
    Ataturk University, Faculty of Pharmacy, Department of Biochemistry, Erzurum, Turkey
    J Ethnopharmacol 103:59-65. 2006
    ..These results suggest that the gastroprotective effect of UA can be attributed to its reducing effect on the oxidative damage and neutrophil infiltration in tissues...
  4. ncbi The effects of methanol extract of Lobaria pulmonaria, a lichen species, on indometacin-induced gastric mucosal damage, oxidative stress and neutrophil infiltration
    Basak Karakus
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey
    Phytother Res 23:635-9. 2009
    ..The present results suggested that Lobaria pulmonaria has a gastroprotective effect, probably due to reducing oxidative stress and neutrophil infiltration...
  5. ncbi Growth hormone reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
    Murat Yigiter
    Department of Pediatric Surgery, Ataturk University School of Medicine, Erzurum, Turkey
    Eur J Obstet Gynecol Reprod Biol 157:94-100. 2011
    ..To evaluate the effects of growth hormone (GH) as an antioxidant and tissue-protective agent and analyse the biochemical and histopathological changes in rat ovaries due to experimental ischemia and ischemia/reperfusion injury...
  6. ncbi The effects of diabetes and/or polymicrobial sepsis on the status of antioxidant enzymes and pro-inflammatory cytokines on heart, liver, and lung of ovariectomized rats
    Ayse Albayrak
    Department of Infection Disease, Education and Research Hospital, Erzurum, Turkey
    J Surg Res 169:67-75. 2011
    ..The rat sepsis model in the present study was used to understand the role of sustained hyperglycemia and ovariectomy, either separately or together, on the response of pro-inflammatory mediators and oxidative response...
  7. ncbi Evaluation of anti-inflammatory and antioxidant activities of Peltigera rufescens lichen species in acute and chronic inflammation models
    Sevil Tanas
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkey
    J Nat Med 64:42-9. 2010
    ..The anti-inflammatory effect of MEPR could be attributed to its reducing effect on the neutrophil-derived free radicals and its ameliorating effect on the antioxidant defense systems...
  8. ncbi The role of erythropoietin in the protection of gastric mucosa from indometacin-induced gastric injury and its relationship with oxidant and antioxidant parameters in rats
    Fatih Albayrak
    Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Ataturk University, Erzurum, Turkey
    J Pharm Pharmacol 62:85-90. 2010
    ..Erythropoietin has anti-oxidative and anti-inflammatory activity. We wanted to evaluate its activity in preventing damage to the gastric mucosa...
  9. ncbi Atorvastatin reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
    Elif Cadirci
    Department of Pharmacology, Faculty of Pharmacy, Ataturk University, 25240 Erzurum, Turkey
    Naunyn Schmiedebergs Arch Pharmacol 381:455-66. 2010
    ..Administration of atorvastatin is effective in reversing tissue damage induced by ischemia and/or I/R in ovaries...
  10. ncbi Beneficial effects of vegetable oils (corn, olive and sunflower oils) and alpha-tocopherol on anti-inflammatory and gastrointestinal profiles of indomethacin in rats
    Fehmi Odabasoglu
    Department of Biochemistry, Ataturk University, 25240, Erzurum, Turkey
    Eur J Pharmacol 591:300-6. 2008
    ..These results suggest that indomethacin as well as other NSAIDs do not have any adverse effect on the gastrointestinal tract when they are used together with vegetable oils and vitamin E or as the preparations of the oils...
  11. ncbi Alpha-lipoic acid as a potential target for the treatment of lung injury caused by cecal ligation and puncture-induced sepsis model in rats
    Elif Cadirci
    Department of Pharmacology, Ataturk University Faculty of Medicine, Erzurum, Turkey
    Shock 33:479-84. 2010
    ..We can suggest that ALA showed beneficial effects by decreasing nuclear factor kappaB activation in lung tissues, resulting in decreased serum levels of TNF-alpha and IL-6, and also increasing the antioxidant capacity of the lungs...
  12. ncbi Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism
    Hulya Uzkeser
    Department of Physical Medicine and Rehabilitation, Erzurum Regional Training and Research Hospital, 25240 Erzurum, Turkey
    Mediators Inflamm 2012:438912. 2012
    ..These findings presented here may also shed light on the roles of β-2 adrenergic receptors in inflammatory and hyperalgesic conditions...
  13. ncbi Relationship between oxidative stress and cardiomyopathic changes in ovariectomized rats
    Enbiya Aksakal
    Department of Cardiology, Ataturk University Medical School, Erzurum, Turkey drenbiya yahoo com
    Cardiology 119:235-41. 2011
    ..Menopause has a negative effect on cardiovascular functions. However, very little is known of the overall effect of menopause on the cardiac ultrastructure or the pathophysiological basis of this...
  14. ncbi Antiulcerative effect of dexmedetomidine on indomethacin-induced gastric ulcer in rats
    Beyzagul Polat
    Department of Pharmacology, Faculty of Medicine, Ataturk University, 25240 Erzurum, Turkey
    Pharmacol Rep 63:518-26. 2011
    ..Conversely, aside from myeloperoxidase (MPO), all oxidant parameters decreased. Therefore, oxidant/antioxidant parameters play a role in the antiulcer mechanism of dexmedetomidine...
  15. ncbi Amiodarone has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced paw edema
    Zekai Halici
    Faculty of Medicine, Department of Pharmacology, Ataturk University, 25240, Erzurum, Turkey
    Eur J Pharmacol 566:215-21. 2007
    ..These results suggest that the anti-inflammatory effect of amiodarone on carrageenan-induced acute inflammation can be attributed to its ameliorating effect on the oxidative damage...
  16. ncbi The effects of testosterone on intestinal ischemia/reperfusion in rats
    Yavuz Albayrak
    Department of Surgery, Education and Research Hospital, Yildizkent, Erzurum, Turkey
    J Invest Surg 24:283-91. 2011
    ....
  17. ncbi Comparison of antioxidant activity and phenolic content of three lichen species
    Fehmi Odabasoglu
    Ataturk University, Faculty of Pharmacy, Department of Biochemistry 25240-Campus, Erzurum, Turkey
    Phytother Res 18:938-41. 2004
    ..On the other hand, there was a strong correlation between the reducing powers and the total phenolic contents of the extracts. The highest reducing power was determined for the methanol extract of L. pulmonaria...
  18. ncbi Protective effects of montelukast on ischemia-reperfusion injury in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
    Akgun Oral
    Department of Pediatric Surgery, School of Medicine, Ataturk University, Erzurum, Turkey
    Fertil Steril 95:1360-6. 2011
    ..To reveal the effects of montelukast as an antioxidant and tissue protective agent and study the biochemical and histopathologic changes in experimental ischemia and ischemia-reperfusion (I/R) injury in rat ovaries...
  19. ncbi Protective effects of amlodipine on ischemia-reperfusion injury of rat ovary: biochemical and histopathologic evaluation
    Zekai Halici
    Department of Pharmacology, Ataturk University School of Medicine, Erzurum, Turkey
    Fertil Steril 90:2408-15. 2008
    ..To evaluate the effects of amlodipine as an antioxidant and analyze the histopathologic changes in experimental ischemic and ischemic-reperfusion (I/R) injury in rat ovaries...
  20. ncbi Alpha-lipoic acid protects against indomethacin-induced gastric oxidative toxicity by modulating antioxidant system
    Kursat Ali Kaplan
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, 25240 Erzurum, Turkey
    J Food Sci 77:H224-30. 2012
    ..In conclusion, the gastroprotective effect of ALA could be attributed to its ameliorating effect on the antioxidant defense systems...
  21. ncbi The effects of polymicrobial sepsis with diabetes mellitus on kidney tissues in ovariectomized rats
    Abdullah Uyanik
    Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey
    Ren Fail 32:592-602. 2010
    ..The rats were divided into five groups: sham control (group 1), ovariectomy (group 2), ovariectomy + sepsis (group 3), ovariectomy + diabetes (group 4), and ovariectomy + diabetic + sepsis (group 5)...
  22. ncbi Effects of water extract of Usnea longissima on antioxidant enzyme activity and mucosal damage caused by indomethacin in rats
    M Halici
    Department of Biochemistry, Faculty of Pharmacy Eczacilik Fakultesi, 25240 Campus, Ataturk University, Erzurum, Turkey
    Phytomedicine 12:656-62. 2005
    ..longissima and ranitidine. The present results indicate that the water extract of U. longissima has a protective effect in indomethacin-induced ulcers, which can be attributed to its antioxidant potential...
  23. ncbi Anti-inflammatory and antiulcerogenic effects of the aqueous extract of Lobaria pulmonaria (L.) Hoffm
    H Suleyman
    Ataturk University, Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey
    Phytomedicine 10:552-7. 2003
    ..The carrageenan-induced paw edema, cotton pellet granuloma and indomethacin-induced gastric damage models were used to determine these effects. The extract exhibited moderate anti-inflammatory and strong antiulcerogenic activities...
  24. ncbi The inhibition of gastric mucosal lesion, oxidative stress and neutrophil-infiltration in rats by the lichen constituent diffractaic acid
    Y Bayir
    Department of Biochemistry, Faculty of Pharmacy, Ataturk University, 25240, Campus, Erzurum, Turkey
    Phytomedicine 13:584-90. 2006
    ..These results suggest that the gastroprotective effect of DA can be attributed to its enhancing effects on antioxidant defense systems as well as reducing effects of neutrophil infiltration...
  25. ncbi Gastroprotective and antioxidant effects of montelukast on indomethacin-induced gastric ulcer in rats
    Gunnur Ozbakis Dengiz
    Department of Pharmacology, Faculty of Medicine, Karaelmas University, Turkey
    J Pharmacol Sci 105:94-102. 2007
    ..These results suggest that the gastroprotective effects of montelukast on indomethacin-induced ulcerations can be attributed to its ameliorating effect on oxidative damage and MPO activity...