Ganiya Oboh

Summary

Publications

  1. Saliu J, Oboh G, Omojokun O, Rocha J, Schetinger M, Guterries J, et al. Effect of dietary supplementation of Padauk (Pterocarpus soyauxii) leaf on high fat diet/streptozotocin induced diabetes in rats' brain and platelets. Biomed Pharmacother. 2016;84:1194-1201 pubmed publisher
    ..This study demonstrated that Padauk leaf exhibited modulatory effects on purinergic and cholinergic enzymes involved in the prevention of platelet abnormality and consequent vascular complications in diabetic state. ..
  2. Oboh G, Ademiluyi A, Faloye Y. Effect of combination on the antioxidant and inhibitory properties of tropical pepper varieties against ?-amylase and ?-glucosidase activities in vitro. J Med Food. 2011;14:1152-8 pubmed publisher
    ..The pepper combination showed additive tendencies of these properties. ..
  3. Oboh G, Agunloye O, Akinyemi A, Ademiluyi A, Adefegha S. Comparative study on the inhibitory effect of caffeic and chlorogenic acids on key enzymes linked to Alzheimer's disease and some pro-oxidant induced oxidative stress in rats' brain-in vitro. Neurochem Res. 2013;38:413-9 pubmed publisher
    ..However, esterification of caffeic acid with quinic acid producing chlorogenic acid affects these neuroprotective properties. ..
  4. Akomolafe S, Oboh G, Akindahunsi A, Afolayan A. Tetracarpidium conophorum (Mull.Arg) Hutch & Dalziel inhibits FeSO4-induced lipid peroxidation in rat's genitals. BMC Complement Altern Med. 2015;15:57 pubmed publisher
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  5. request reprint
    Oboh G, Ademosun A, Ogunsuyi O. Quercetin and Its Role in Chronic Diseases. Adv Exp Med Biol. 2016;929:377-387 pubmed
    ....
  6. Oboh G, Ogunsuyi O, Olonisola O. Does caffeine influence the anticholinesterase and antioxidant properties of donepezil? Evidence from in vitro and in vivo studies. Metab Brain Dis. 2017;32:629-639 pubmed publisher
    ....
  7. request reprint
    Shodehinde S, Adefegha S, Oboh G, Oyeleye S, Olasehinde T, Nwanna E, et al. Phenolic Composition and Evaluation of Methanol and Aqueous Extracts of Bitter Gourd (Momordica charantia L) Leaves on Angiotensin-I-Converting Enzyme and Some Pro-oxidant-Induced Lipid Peroxidation In Vitro. J Evid Based Complementary Altern Med. 2016;21:NP67-NP76 pubmed
    ..Thus, inhibition of angiotensin-I converting enzyme activity and the antioxidant properties of the extracts could be linked to the presence of phenolic phytochemicals. ..
  8. Oboh G, Akomolafe T, Adefegha S, Adetuyi A. Inhibition of cyclophosphamide-induced oxidative stress in rat brain by polar and non-polar extracts of Annatto (Bixa orellana) seeds. Exp Toxicol Pathol. 2011;63:257-62 pubmed publisher
    ..Therefore, dietary inclusion of Annato seed extracts as food colourant could prevent oxidative stress occasioned by cyclophosphamide administration, but the non-polar extract is a better protectant. ..
  9. Oboh G, Rocha J. Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro. J Med Food. 2008;11:349-55 pubmed publisher
    ..However, unripe CAT has the highest protective properties against sodium nitroprusside- and quinolinic acid-induced lipid peroxidation in rat brain...
  10. Oboh G, Henle T. Antioxidant and inhibitory effects of aqueous extracts of Salvia officinalis leaves on pro-oxidant-induced lipid peroxidation in brain and liver in vitro. J Med Food. 2009;12:77-84 pubmed publisher
    ..OH radical scavenging ability. This antioxidant and protective effect of this leaf could be harnessed in the management and prevention of degenerative diseases associated with oxidative stress...

Locale

Detail Information

Publications15

  1. Saliu J, Oboh G, Omojokun O, Rocha J, Schetinger M, Guterries J, et al. Effect of dietary supplementation of Padauk (Pterocarpus soyauxii) leaf on high fat diet/streptozotocin induced diabetes in rats' brain and platelets. Biomed Pharmacother. 2016;84:1194-1201 pubmed publisher
    ..This study demonstrated that Padauk leaf exhibited modulatory effects on purinergic and cholinergic enzymes involved in the prevention of platelet abnormality and consequent vascular complications in diabetic state. ..
  2. Oboh G, Ademiluyi A, Faloye Y. Effect of combination on the antioxidant and inhibitory properties of tropical pepper varieties against ?-amylase and ?-glucosidase activities in vitro. J Med Food. 2011;14:1152-8 pubmed publisher
    ..The pepper combination showed additive tendencies of these properties. ..
  3. Oboh G, Agunloye O, Akinyemi A, Ademiluyi A, Adefegha S. Comparative study on the inhibitory effect of caffeic and chlorogenic acids on key enzymes linked to Alzheimer's disease and some pro-oxidant induced oxidative stress in rats' brain-in vitro. Neurochem Res. 2013;38:413-9 pubmed publisher
    ..However, esterification of caffeic acid with quinic acid producing chlorogenic acid affects these neuroprotective properties. ..
  4. Akomolafe S, Oboh G, Akindahunsi A, Afolayan A. Tetracarpidium conophorum (Mull.Arg) Hutch & Dalziel inhibits FeSO4-induced lipid peroxidation in rat's genitals. BMC Complement Altern Med. 2015;15:57 pubmed publisher
    ....
  5. request reprint
    Oboh G, Ademosun A, Ogunsuyi O. Quercetin and Its Role in Chronic Diseases. Adv Exp Med Biol. 2016;929:377-387 pubmed
    ....
  6. Oboh G, Ogunsuyi O, Olonisola O. Does caffeine influence the anticholinesterase and antioxidant properties of donepezil? Evidence from in vitro and in vivo studies. Metab Brain Dis. 2017;32:629-639 pubmed publisher
    ....
  7. request reprint
    Shodehinde S, Adefegha S, Oboh G, Oyeleye S, Olasehinde T, Nwanna E, et al. Phenolic Composition and Evaluation of Methanol and Aqueous Extracts of Bitter Gourd (Momordica charantia L) Leaves on Angiotensin-I-Converting Enzyme and Some Pro-oxidant-Induced Lipid Peroxidation In Vitro. J Evid Based Complementary Altern Med. 2016;21:NP67-NP76 pubmed
    ..Thus, inhibition of angiotensin-I converting enzyme activity and the antioxidant properties of the extracts could be linked to the presence of phenolic phytochemicals. ..
  8. Oboh G, Akomolafe T, Adefegha S, Adetuyi A. Inhibition of cyclophosphamide-induced oxidative stress in rat brain by polar and non-polar extracts of Annatto (Bixa orellana) seeds. Exp Toxicol Pathol. 2011;63:257-62 pubmed publisher
    ..Therefore, dietary inclusion of Annato seed extracts as food colourant could prevent oxidative stress occasioned by cyclophosphamide administration, but the non-polar extract is a better protectant. ..
  9. Oboh G, Rocha J. Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro. J Med Food. 2008;11:349-55 pubmed publisher
    ..However, unripe CAT has the highest protective properties against sodium nitroprusside- and quinolinic acid-induced lipid peroxidation in rat brain...
  10. Oboh G, Henle T. Antioxidant and inhibitory effects of aqueous extracts of Salvia officinalis leaves on pro-oxidant-induced lipid peroxidation in brain and liver in vitro. J Med Food. 2009;12:77-84 pubmed publisher
    ..OH radical scavenging ability. This antioxidant and protective effect of this leaf could be harnessed in the management and prevention of degenerative diseases associated with oxidative stress...
  11. Oboh G, Raddatz H, Henle T. Characterization of the antioxidant properties of hydrophilic and lipophilic extracts of Jute (Corchorus olitorius) leaf. Int J Food Sci Nutr. 2009;60 Suppl 2:124-34 pubmed publisher
    ..5 mg/100 g). Therefore, the additive/synergistic antioxidant activities of the hydrophilic and lipophilic constituents may contribute to the medicinal properties of C. olitorius leaf...
  12. Oboh G, Akinyemi A, Ademiluyi A. Antioxidant and inhibitory effect of red ginger (Zingiber officinale var. Rubra) and white ginger (Zingiber officinale Roscoe) on Fe(2+) induced lipid peroxidation in rat brain in vitro. Exp Toxicol Pathol. 2012;64:31-6 pubmed publisher
    ..Therefore, oxidative stress in the brain could be potentially managed/prevented by dietary intake of ginger varieties (red ginger and white ginger rhizomes)...
  13. Oboh G, Ademiluyi A, Akinyemi A. Inhibition of acetylcholinesterase activities and some pro-oxidant induced lipid peroxidation in rat brain by two varieties of ginger (Zingiber officinale). Exp Toxicol Pathol. 2012;64:315-9 pubmed publisher
    ..Therefore, some possible mechanism by which ginger extracts exert anti-Alzheimer properties could be through the inhibition of acetylcholinesterase activities and prevention of lipid peroxidation in the brain...
  14. Oboh G, Bello F, Ademosun A. Hypocholesterolemic properties of grapefruit (Citrus paradisii) and shaddock (Citrus maxima) juices and inhibition of angiotensin-1-converting enzyme activity. J Food Drug Anal. 2014;22:477-484 pubmed publisher
    ..The inhibition of ACE activity in vitro and in vivo hypocholesterolemic effect of the juices could explain the use of the juices in the management of cardiovascular diseases. ..
  15. Oboh G, Ogunsuyi O, Ogunbadejo M, Adefegha S. Influence of gallic acid on ?-amylase and ?-glucosidase inhibitory properties of acarbose. J Food Drug Anal. 2016;24:627-634 pubmed publisher
    ..Therefore, combinations of GA with acarbose could be employed as antidiabetic therapy, with a possible reduction of side effects of acarbose; nevertheless, the combination of 50% acarbose and 50% GA seems the best. ..