J P O'Beirne

Summary

Publications

  1. ncbi The role of the immune system in the control of hepatocellular carcinoma
    James P O'Beirne
    Department of Liver Studies and Transplantation, King s College, London, UK
    Eur J Gastroenterol Hepatol 16:1257-60. 2004
  2. ncbi Progression of collagenous colitis to Crohn's disease
    J P O'Beirne
    Digestive Disease Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK
    Eur J Gastroenterol Hepatol 17:573-5. 2005
  3. ncbi Frequency and nature of cytokine gene polymorphisms in hepatocellular carcinoma in Hong Kong Chinese
    Michael A Heneghan
    Institute of Liver Studies, King s College Hospital, London, SE5 9RS, UK
    Int J Gastrointest Cancer 34:19-26. 2003
  4. doi Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening
    Andrew D Yeoman
    Institute of Liver Studies, King s College Hospital National Health Service NHS Foundation Trust, Denmark Hill, London, UK
    Hepatology 48:863-70. 2008
  5. ncbi The increasing prevalence of hepatitis delta virus (HDV) infection in South London
    Timothy J S Cross
    Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    J Med Virol 80:277-82. 2008
  6. doi Inhibition of major histocompatibility complex Class I antigen presentation by hepatitis C virus core protein in myeloid dendritic cells
    James O'Beirne
    Department of Liver Studies and Transplantation, Kings College London, Denmark Hill Campus, London SE59PJ, UK
    Virology 389:1-7. 2009
  7. pmc Generation of functional CD8+ T cells by human dendritic cells expressing glypican-3 epitopes
    James O'Beirne
    Department of Liver Studies and Transplantation, Kings College London, Denmark Hill Campus, Bessemer Road, London, UK
    J Exp Clin Cancer Res 29:48. 2010

Collaborators

Detail Information

Publications7

  1. ncbi The role of the immune system in the control of hepatocellular carcinoma
    James P O'Beirne
    Department of Liver Studies and Transplantation, King s College, London, UK
    Eur J Gastroenterol Hepatol 16:1257-60. 2004
    ..The use of dendritic-cell vaccination raises exciting possibilities of preventing the formation of HCC in high-risk individuals such as those with cirrhosis...
  2. ncbi Progression of collagenous colitis to Crohn's disease
    J P O'Beirne
    Digestive Disease Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK
    Eur J Gastroenterol Hepatol 17:573-5. 2005
    ..We describe a case of diarrhoea presenting in infancy subsequently proved to be collagenous colitis that progressed to the typical features of Crohn's disease...
  3. ncbi Frequency and nature of cytokine gene polymorphisms in hepatocellular carcinoma in Hong Kong Chinese
    Michael A Heneghan
    Institute of Liver Studies, King s College Hospital, London, SE5 9RS, UK
    Int J Gastrointest Cancer 34:19-26. 2003
    ..The genetic basis of susceptibility to hepatocellular carcinoma (HCC) is poorly understood. Genomic DNA was available from 98 patients with HCC, 77 familial controls, 97 controls from Hong Kong and 96 Northern European controls (NECs)...
  4. doi Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening
    Andrew D Yeoman
    Institute of Liver Studies, King s College Hospital National Health Service NHS Foundation Trust, Denmark Hill, London, UK
    Hepatology 48:863-70. 2008
    ..5 months, range 12-195 months. Median survival in patients whose HCC was diagnosed on surveillance was 19 months (range 6-36 months) compared with 2 months (range 0-14 months) for patients presenting symptomatically (P = 0.042)...
  5. ncbi The increasing prevalence of hepatitis delta virus (HDV) infection in South London
    Timothy J S Cross
    Institute of Liver Studies, King s College Hospital, Denmark Hill, London, UK
    J Med Virol 80:277-82. 2008
    ..HDV co-infection is associated with increased morbidity and patients with HBV should be tested for HDV infection...
  6. doi Inhibition of major histocompatibility complex Class I antigen presentation by hepatitis C virus core protein in myeloid dendritic cells
    James O'Beirne
    Department of Liver Studies and Transplantation, Kings College London, Denmark Hill Campus, London SE59PJ, UK
    Virology 389:1-7. 2009
    ..Exploitation of the MHC class I antigen-processing pathway by HCVcore(191) impairs the ability of DC to stimulate CD8+ T cells and may contribute to the persistence of HCV infection...
  7. pmc Generation of functional CD8+ T cells by human dendritic cells expressing glypican-3 epitopes
    James O'Beirne
    Department of Liver Studies and Transplantation, Kings College London, Denmark Hill Campus, Bessemer Road, London, UK
    J Exp Clin Cancer Res 29:48. 2010
    ..Since it is a potential target for T cell immunotherapy, we investigated the generation of functional, GPC-3 specific T cells from peripheral blood mononuclear cells (PBMC)...