Prospects for pneumococcal vaccination in African childrenS K Obaro
Medical Research Council Laboratories, PO Box 273, Fajara, Gambia
Acta Trop 75:141-53. 2000
..Establishing disease surveillance systems in such countries now will greatly facilitate the introduction of the vaccines...
- Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants
S K Obaro
Medical Research Council Laboratories, Fajara, The Gambia
Pediatr Infect Dis J 19:463-9. 2000
..Unrelenting high morbidity and mortality have mandated that immunogenic vaccines be used to combat pneumococcal disease in infants...
- Confronting the pneumococcus: a target shift or bullet change?
S K Obaro
Medical Research Council Laboratories, P O Box 273, Fajara, Gambia
Vaccine 19:1211-7. 2000
..As currently available diagnostic methods are poorly sensitive, the true burden of pneumococcal disease may not be revealed until there is a highly efficacious vaccine in widespread use...
- A glycoprotein pneumococcal conjugate vaccine primes for antibody responses to a pneumococcal polysaccharide vaccine in Gambian children
S K Obaro
Medical Research Council Laboratories, Fajara, The Gambia
Pediatr Infect Dis J 16:1135-40. 1997
..Pneumococcal polysaccharide vaccines are poorly immunogenic in this highly vulnerable group, but protein polysaccharide conjugate vaccines are likely to be more effective...
- Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial
F T Cutts
Medical Research Council Laboratories, Banjul, The Gambia
Lancet 365:1139-46. 2005
..Pneumococcal conjugate vaccines should be made available to African infants...
- Electrolyte derangement in cerebral malaria: a case for a more aggressive approach to the management of hyponatraemia
G C Enwere
Medical Research Council Laboratories, Fajara, Banjul, The Gambia
Ann Trop Med Parasitol 94:541-7. 2000
..In addition, children admitted with cerebral malaria should have their electrolyte status monitored to identify new or ongoing hyponatraemia. When hyponatraemia is discovered, it should be quickly and actively corrected...
- The host response in malaria and depression of defence against tuberculosis
G C Enwere
Medical Research Council Laboratories, Fajara, The Gambia
Ann Trop Med Parasitol 93:669-78. 1999
..Could malarial infection be one of the reasons for the persistence of tuberculosis in malaria-endemic regions?..
- Diagnosis of childhood pneumonia in the tropics
R A Adegbola
Pneumonia Research Programme, Medical Research Council Laboratories, Fajara, Banjul
Ann Trop Med Parasitol 94:197-207. 2000
..There is, however, considerable scope to improve the use of the cheaper techniques, and so facilitate the development and implementation of effective control measures...
