Mette Nyegaard

Summary

Publications

  1. pmc Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death
    Mette Nyegaard
    Department of Biomedicine, Aarhus University, DK 8000 Aarhus, Denmark
    Am J Hum Genet 91:703-12. 2012
  2. doi request reprint No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia
    Mette Nyegaard
    Department of Haematology, Aalborg Hospital Science and Innovation Center, Aarhus University Hospital, Aalborg, Denmark
    Psychiatr Genet 22:146-8. 2012
  3. pmc Validation and implementation of a method for microarray gene expression profiling of minor B-cell subpopulations in man
    Kim Steve Bergkvist
    Department of Haematology, Aalborg University Hospital Science and Innovation Center, Sdr Skovvej 15, DK 9000 Aalborg, Denmark
    BMC Immunol 15:3. 2014
  4. ncbi request reprint Exposure time independent summary statistics for assessment of drug dependent cell line growth inhibition
    Steffen Falgreen
    Department of Haematology, Aalborg University Hospital, Aalborg, Denmark
    BMC Bioinformatics 15:168. 2014
  5. doi request reprint The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress
    Jane H Christensen
    Department of Biomedicine, Aarhus University, Denmark
    Eur Neuropsychopharmacol 22:651-6. 2012
  6. doi request reprint Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk
    Ditte Demontis
    Department of Human Genetics, Aarhus University, Aarhus, Denmark
    Am J Med Genet B Neuropsychiatr Genet 156:913-22. 2011
  7. doi request reprint The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case-control sample
    Ditte Demontis
    Department of Human Genetics, Aarhus University, Arhus, Denmark
    Psychiatr Genet 22:62-9. 2012
  8. pmc A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene
    Noomi Gregersen
    Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Aarhus, Denmark
    Eur J Hum Genet 20:84-90. 2012
  9. doi request reprint A major imprinted gene involved in hydatidiform mole is not located in 2q31.2-qter or 5q34-qter
    Helle Lund
    Aarhus University Hospital, Aalborg, Denmark
    Gene 497:280-4. 2012
  10. pmc A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families
    Lisbeth Venø Kruse
    Department of Biomedicine, Aarhus University, Aarhus, Denmark
    Eur J Hum Genet 20:965-72. 2012

Collaborators

Detail Information

Publications16

  1. pmc Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death
    Mette Nyegaard
    Department of Biomedicine, Aarhus University, DK 8000 Aarhus, Denmark
    Am J Hum Genet 91:703-12. 2012
    ....
  2. doi request reprint No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia
    Mette Nyegaard
    Department of Haematology, Aalborg Hospital Science and Innovation Center, Aarhus University Hospital, Aalborg, Denmark
    Psychiatr Genet 22:146-8. 2012
    ..However, one HERV-K18 SNP showed a tendency toward an association with T2D in younger SZ patients, in agreement with previous findings, but due to a very low sample size, this result needs to be further investigated...
  3. pmc Validation and implementation of a method for microarray gene expression profiling of minor B-cell subpopulations in man
    Kim Steve Bergkvist
    Department of Haematology, Aalborg University Hospital Science and Innovation Center, Sdr Skovvej 15, DK 9000 Aalborg, Denmark
    BMC Immunol 15:3. 2014
    ..However, some of the differentiating compartments involve a low number of cells and therefore it is important to optimize and validate each step in the procedure...
  4. ncbi request reprint Exposure time independent summary statistics for assessment of drug dependent cell line growth inhibition
    Steffen Falgreen
    Department of Haematology, Aalborg University Hospital, Aalborg, Denmark
    BMC Bioinformatics 15:168. 2014
    ..This may lead to suboptimal exploitation of data and biased conclusions on the potential of the drug in question. Therefore we set out to improve the dose-response assessments by eliminating the impact of time dependency...
  5. doi request reprint The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress
    Jane H Christensen
    Department of Biomedicine, Aarhus University, Denmark
    Eur Neuropsychopharmacol 22:651-6. 2012
    ....
  6. doi request reprint Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk
    Ditte Demontis
    Department of Human Genetics, Aarhus University, Aarhus, Denmark
    Am J Med Genet B Neuropsychiatr Genet 156:913-22. 2011
    ..0008). The significant associations and interactions were located at the 3' region of GRIN2B suggesting that genetic variation in this part of the gene may be involved in the pathophysiology of schizophrenia...
  7. doi request reprint The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case-control sample
    Ditte Demontis
    Department of Human Genetics, Aarhus University, Arhus, Denmark
    Psychiatr Genet 22:62-9. 2012
    ..Herein we report an association between variations in the MCHR1 gene and schizophrenia, based on analyses of a larger sample and an increased number of single nucleotide polymorphisms (SNPs) than used in the previous study...
  8. pmc A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene
    Noomi Gregersen
    Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Aarhus, Denmark
    Eur J Hum Genet 20:84-90. 2012
    ..This suggests that the possible risk alleles associated in the isolated population are not those involved in the development of PD in a larger outbred population...
  9. doi request reprint A major imprinted gene involved in hydatidiform mole is not located in 2q31.2-qter or 5q34-qter
    Helle Lund
    Aarhus University Hospital, Aalborg, Denmark
    Gene 497:280-4. 2012
    ..However it remains yet to be specified which gene(s) in the molar genome actually causes the molar phenotype when present in a state of "paternal excess" or "maternal deficiency"...
  10. pmc A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families
    Lisbeth Venø Kruse
    Department of Biomedicine, Aarhus University, Aarhus, Denmark
    Eur J Hum Genet 20:965-72. 2012
    ..Likely maternal imprinting was observed at 2q23, and possible maternal imprinting at 3q28...
  11. pmc Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects
    Kaspar R Nielsen
    Department of Clinical Immunology, Aalborg Hospital, Aarhus University Hospital, Reberbansgade, Pobox 561, 9000, Aalborg, Denmark
    Arthritis Res Ther 13:R109. 2011
    ..YKL-40 concentrations are elevated in the serum of patients with RA compared to healthy subjects, and YKL-40 has been suggested to be an auto-antigen and may play a role in development of RA and in inflammation...
  12. doi request reprint Multiparametric flow cytometry for identification and fluorescence activated cell sorting of five distinct B-cell subpopulations in normal tonsil tissue
    Malene Krag Kjeldsen
    Department of Haematology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
    Am J Clin Pathol 136:960-9. 2011
    ..This study has established a detailed and fast procedure for simultaneous sorting of up to 5 distinct maturation-associated B-cell subpopulations from human tonsils...
  13. doi request reprint Clinical impact of leukemic blast heterogeneity at diagnosis in cytogenetic intermediate-risk acute myeloid leukemia
    Marianne Hutchings Hoffmann
    Department of Haematology, Herlev University Hospital, Copenhagen, Denmark
    Cytometry B Clin Cytom 82:123-31. 2012
    ....
  14. ncbi request reprint The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion
    Camilla Gustafsen
    The Lundbeck Foundation Research Center, Mind, Department of Biomedicine, Aarhus University, Vennelyst Boulevard 4, DK 8000 C Aarhus, Denmark
    Cell Metab 19:310-8. 2014
    ..Taken together, our findings establish sortilin as a critical regulator of PCSK9 activity. ..
  15. pmc A model system for assessing and comparing the ability of exon microarray and tag sequencing to detect genes specific for malignant B-cells
    Maria Bro Kloster
    Department of Haematology, Aalborg Hospital, Aarhus University Hospital, Sdr Skovvej 15, 9000 Aalborg, Denmark
    BMC Genomics 13:596. 2012
    ..A model system was established by eight serial dilutions of the malignant B-cell lymphoma cell line, OCI-Ly8, into the embryonic kidney cell line, HEK293, prior to parallel analysis by exon microarrays and tag-seq...
  16. doi request reprint Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3
    Henriette Nørmølle Buttenschøn
    Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark
    Psychiatr Genet 20:93-101. 2010
    ..Linkage and association studies of bipolar affective disorder (BAD) point out chromosome 12q24 as a region of interest...