Abdelmalik Slassi

Summary

Affiliation: NPS Pharmaceuticals

Publications

  1. ncbi request reprint 3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT(1B/1D) ligands
    Ian Egle
    NPS Pharmaceuticals Inc, 6850 Goreway Dr, Mississauga, Ontario, Canada L4V 1V7
    Bioorg Med Chem Lett 14:727-9. 2004
  2. ncbi request reprint Recent advances in 5-HT1B/1D receptor antagonists and agonists and their potential therapeutic applications
    Abdelmalik Slassi
    Medicinal Chemistry Department, NPS Pharmaceuticals, 6850 Goreway Drive, Mississauga, Ontario, L4V 1V7, Canada
    Curr Top Med Chem 2:559-74. 2002
  3. ncbi request reprint Recent advances in non-competitive mGlu5 receptor antagonists and their potential therapeutic applications
    Abdelmalik Slassi
    NPS Pharmaceuticals Inc 6850 Goreway Drive, Mississauga, ON, Canada, L4V 1V7
    Curr Top Med Chem 5:897-911. 2005
  4. ncbi request reprint (R)-3-(N-methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity h5-HT1B/1D ligands
    Ian Egle
    NPS Pharmaceuticals Inc, 6850 Goreway Dr, Mississauga, Ontario, Canada L4V 1V7
    Bioorg Med Chem Lett 13:3419-21. 2003
  5. ncbi request reprint 1-(Bicyclopiperazinyl)ethylindoles and 1-(homopiperazinyl)ethyl-indoles as highly selective and potent 5-HT(7) receptor ligands
    Methvin B Isaac
    NPS Pharmaceuticals Inc, Mississauga, ON, Canada
    Bioorg Med Chem Lett 12:2451-4. 2002
  6. ncbi request reprint 2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands
    Thomas Prisinzano
    Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA
    Bioorg Med Chem Lett 14:4697-9. 2004

Collaborators

Detail Information

Publications6

  1. ncbi request reprint 3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT(1B/1D) ligands
    Ian Egle
    NPS Pharmaceuticals Inc, 6850 Goreway Dr, Mississauga, Ontario, Canada L4V 1V7
    Bioorg Med Chem Lett 14:727-9. 2004
    ..High affinity human 5-HT(1B/1D) (h5-HT(1B/1D)) ligands have been identified...
  2. ncbi request reprint Recent advances in 5-HT1B/1D receptor antagonists and agonists and their potential therapeutic applications
    Abdelmalik Slassi
    Medicinal Chemistry Department, NPS Pharmaceuticals, 6850 Goreway Drive, Mississauga, Ontario, L4V 1V7, Canada
    Curr Top Med Chem 2:559-74. 2002
    ..By no means has any attempt been made to exhaustively review the literature but rather, primary references along with citations to recent literature reviews have been included in each section...
  3. ncbi request reprint Recent advances in non-competitive mGlu5 receptor antagonists and their potential therapeutic applications
    Abdelmalik Slassi
    NPS Pharmaceuticals Inc 6850 Goreway Drive, Mississauga, ON, Canada, L4V 1V7
    Curr Top Med Chem 5:897-911. 2005
    ..Emphasis is also given to recent advances in the potential therapeutic applications of non-competitive mGlu5 receptor antagonists...
  4. ncbi request reprint (R)-3-(N-methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity h5-HT1B/1D ligands
    Ian Egle
    NPS Pharmaceuticals Inc, 6850 Goreway Dr, Mississauga, Ontario, Canada L4V 1V7
    Bioorg Med Chem Lett 13:3419-21. 2003
    ..High affinity human 5-HT(1B/1D) (h5-HT(1B/1D)) ligands have been identified...
  5. ncbi request reprint 1-(Bicyclopiperazinyl)ethylindoles and 1-(homopiperazinyl)ethyl-indoles as highly selective and potent 5-HT(7) receptor ligands
    Methvin B Isaac
    NPS Pharmaceuticals Inc, Mississauga, ON, Canada
    Bioorg Med Chem Lett 12:2451-4. 2002
    ..A novel series of 1-(bicyclopiperazinyl)ethylindole and 1-(homopiperazinyl)ethyl-indole derivatives was synthesized and found to be potent and selective 5-HT(7) receptor ligands...
  6. ncbi request reprint 2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands
    Thomas Prisinzano
    Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA
    Bioorg Med Chem Lett 14:4697-9. 2004
    ..Pharmacokinetic and functional data were obtained for selected 2-(benzyl)imidazoline derivatives...