Claudia Zuany Amorim
Affiliation: Novartis Institutes for BioMedical Research
- Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cellsClaudia Zuany-Amorim
Novartis Horsham Research Centre, Novartis Pharmaceutical Ltd Wimblehurst Road, Horsham, UK
Nat Med 8:625-9. 2002..Thus, regulatory T cells generated by mycobacteria treatment may have an essential role in restoring the balance of the immune system to prevent and treat allergic diseases...
- Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammationClaudia Zuany-Amorim
Novartis Horsham Research Center, Novartis Pharmaceutical Ltd, Horsham, United Kingdom
J Immunol 169:1492-9. 2002....
- Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720Elzbieta Sawicka
Novartis Horsham Research Centre, Horsham, U K
J Immunol 171:6206-14. 2003....
- Induction of TNF-alpha autoantibody production by AutoVac TNF106: a novel therapeutic approach for the treatment of allergic diseasesClaudia Zuany-Amorim
Novartis Horsham Research Centre, Novartis Pharmaceutical Ltd, Horsham, UK
Int Arch Allergy Immunol 133:154-63. 2004..The present work describes a simple and effective method to induce the production of therapeutic anti-cytokine autoantibodies by active immunization against a modified endogenous cytokine...
- Toll-like receptors as potential therapeutic targets for multiple diseasesClaudia Zuany-Amorim
Novartis Horsham Research Centre, Novartis Pharmaceutical Ltd, Wimblehurst Road, Horsham, West Sussex RH12 5AB, UK
Nat Rev Drug Discov 1:797-807. 2002..In this review, we discuss the current and future use of TLR agonists or antagonists in chronic inflammatory diseases and highlight potential problems that are associated with such approaches...
- Inhibition of interleukin-1beta reduces mouse lung inflammation induced by exposure to cigarette smokePaulo Castro
Departamento de Bioquimica Medica, ICB, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941 590, Brazil
Eur J Pharmacol 498:279-86. 2004....