Emily C Walsh

Summary

Affiliation: Novartis Institutes for BioMedical Research

Publications

  1. ncbi request reprint Searching for signals of evolutionary selection in 168 genes related to immune function
    Emily C Walsh
    Novartis Institutes for BioMedical Research, 250 Mass Ave, Cambridge, MA 02139, USA
    Hum Genet 119:92-102. 2006
  2. pmc A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
    Paul I W de Bakker
    Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Seven Cambridge Center, Cambridge, Massachusetts 02142, USA
    Nat Genet 38:1166-72. 2006
  3. ncbi request reprint Genetic analysis of multiple sclerosis
    Emily C Walsh
    Whitehead Institute for Biomedical Research, Center for Genome Research, One Kendall Square, Cambridge, MA 02141, USA
    J Autoimmun 21:111-6. 2003
  4. pmc An integrated haplotype map of the human major histocompatibility complex
    Emily C Walsh
    Center for Genome Research, Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA
    Am J Hum Genet 73:580-90. 2003
  5. pmc Identification of two independent risk factors for lupus within the MHC in United Kingdom families
    Michelle M A Fernando
    Section of Molecular Genetics and Rheumatology, Imperial College London, London, United Kingdom
    PLoS Genet 3:e192. 2007
  6. ncbi request reprint Erythroid-lineage-specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation
    Paul M Armistead
    Department of Medical Oncology, M D Anderson Cancer Center, Houston, TX, USA
    Exp Hematol 36:1205-15. 2008
  7. pmc Early myocardial function affects endocardial cushion development in zebrafish
    Thomas Bartman
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, USA
    PLoS Biol 2:E129. 2004
  8. pmc A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms
    Marcos M Miretti
    Wellcome Trust Sanger Institute, Hinxton, United Kingdom
    Am J Hum Genet 76:634-46. 2005
  9. pmc Defining the role of the MHC in autoimmunity: a review and pooled analysis
    Michelle M A Fernando
    Section of Molecular Genetics and Rheumatology, Faculty of Medicine, Imperial College London, London, United Kingdom
    PLoS Genet 4:e1000024. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Searching for signals of evolutionary selection in 168 genes related to immune function
    Emily C Walsh
    Novartis Institutes for BioMedical Research, 250 Mass Ave, Cambridge, MA 02139, USA
    Hum Genet 119:92-102. 2006
    ....
  2. pmc A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
    Paul I W de Bakker
    Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Seven Cambridge Center, Cambridge, Massachusetts 02142, USA
    Nat Genet 38:1166-72. 2006
    ....
  3. ncbi request reprint Genetic analysis of multiple sclerosis
    Emily C Walsh
    Whitehead Institute for Biomedical Research, Center for Genome Research, One Kendall Square, Cambridge, MA 02141, USA
    J Autoimmun 21:111-6. 2003
    ..Lastly, we review recent important advances in our understanding of the patterns of genetic variation in the human genome and speculate about how these advances will aid in future studies of the genetic causes of MS...
  4. pmc An integrated haplotype map of the human major histocompatibility complex
    Emily C Walsh
    Center for Genome Research, Whitehead Institute for Biomedical Research, Cambridge, MA 02139, USA
    Am J Hum Genet 73:580-90. 2003
    ..Furthermore, these data show that multi-SNP haplotypes will likely be a valuable means for refining association signals in this region...
  5. pmc Identification of two independent risk factors for lupus within the MHC in United Kingdom families
    Michelle M A Fernando
    Section of Molecular Genetics and Rheumatology, Imperial College London, London, United Kingdom
    PLoS Genet 3:e192. 2007
    ..Our class III signal importantly excludes independent association at the TNF promoter polymorphism, TNF-308G/A, in our SLE cohort and provides a potentially novel locus for future genetic and functional studies...
  6. ncbi request reprint Erythroid-lineage-specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation
    Paul M Armistead
    Department of Medical Oncology, M D Anderson Cancer Center, Houston, TX, USA
    Exp Hematol 36:1205-15. 2008
    ..We aimed to create a molecular assay to monitor erythroid (red blood cell [RBC]) engraftment in any patient following allogeneic hematopoietic stem cell transplantation, independent of disease-specific mutations...
  7. pmc Early myocardial function affects endocardial cushion development in zebrafish
    Thomas Bartman
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, USA
    PLoS Biol 2:E129. 2004
    ....
  8. pmc A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms
    Marcos M Miretti
    Wellcome Trust Sanger Institute, Hinxton, United Kingdom
    Am J Hum Genet 76:634-46. 2005
    ..This LD map allowed us to give coordinates for the extremely variable LD structure underlying the MHC...
  9. pmc Defining the role of the MHC in autoimmunity: a review and pooled analysis
    Michelle M A Fernando
    Section of Molecular Genetics and Rheumatology, Faculty of Medicine, Imperial College London, London, United Kingdom
    PLoS Genet 4:e1000024. 2008
    ..Furthermore, we find a number of interesting commonalities and differences across diseases that implicate both general and disease-specific pathogenetic mechanisms in autoimmunity...